• Reproductive and Developmental Biology
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• v.33 no.4
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• pp.217-222
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• 2009

The purpose of this study is to evaluate the effects of alcohol or cigarette smoking on seminal parameters in a large group of mice model. Nine groups (n=20/group) of mice were treated intensive noxious materials that abdominal injection of 21% (v/v) of ethanol, cigarette smoke (10, 20, 30 minutes/day), and combination of ethanol and 30 minutes of smoking. In addition, vitamin C and selenium were also treated to mice exposed to combination of alcohol and smoking to identify the recovering effect. Sperm viability and motility were significantly decreased in either alcohol consumption or smoking exposed group, and combination of both materials have additive detrimental effects on seminal parameters. Mice groups that exposed to alcohol and smoking showed statistically significant decrease in motility and increase of static spermatozoa. Moreover, combination of both treatments showed cumulative effect in increase of static spermatozoa. Treatments of either vitamin C or selenium dramatically recovered detrimental effects of alcohol and smoking on seminal quality, although combination of both antioxidant molecules did not show any additive effect. In conclusion, detrimental effects of alcohol and cigarette consumption on sperm quality and motility were identified in mice model, and these detrimental effects can be compensated to uptake of anti-oxidant molecules.

• Journal of Korean Public Health Nursing
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• v.21 no.1
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• pp.37-45
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• 2007

Purpose: A diverse range of measurement methods to evaluate the effect of smoking is more powerful than using a single measure. The objectives of this study were to examine the relationships among smoking pack year, self-reported smoking dependence, and urinary cotinine levels, and to investigate the psychological variables in working men. Method: In this cross-sectional study, we surveyed men working in an electronic company who participated in a smoking cessation program. Among 57 men who completed questionnaires, 25 participate in a test for cotinine levels. Results: Smoking pack year was significantly and positively correlated with the FTND-K (Korean version of Fagerstrom test for nicotine dependence) sum scores (r=0.631, p=0.000) and with the levels of urine cotinine (r=0.463, p=0.023). The relationship between FTND-K sum scores and urinary cotinine levels was also significantly positive (r=0.639, p=0.001). Those with higher social support, especially family support, tended to perceive a higher self-efficacy to smoking cessation. Conclusion: These findings suggest that self-reported smoking pack year and nicotine dependence in working men may be a valid way to evaluate the effect of smoking. A supportive family may influence smoking cessation in working men as it increases self-efficacy to avoid smoking.

• Journal of Nutrition and Health
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• v.33 no.2
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• pp.167-178
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• 2000

The effect of oral vitamin e (800IU/day) and C (500mg/day) supplementation for 10 days and/or smoking cessation for 5 days on oxidative damage to the red blood cells (RBC) of male smokers (22.2$\pm$0.2 years old) was studied. RBC were tested for their ability to protect against smoking-induced oxidative damage by measuring heme proteins (carboxyhemoglobin, hemoglobin, methemoglobin, oxyhemoglobin), hemolysis and thiobarbiturinc acid reactive substances (TBARS). Plasma levels of vitamin c, A, E, $\beta$-catotene, total cholesterol, glutamic pyruvic transaminase(GPT) and glutamic oxaloacetic transaminase(GOT) were also analyzed. In experiment one, a comparison was made of heme proteins and lipid damage to RBC, plasma antioxidant status (indexed by plasma levels of vitamin C, E, A and $\beta$-carotene) between smokers(n=56) and non-smokers (n=16). No differences were found in plasma antioxidant status, heme protein damage and TBARS concentration of RBC. In experiment two, 46 fasting male smokers from experiment one were divided into 4 groups. The groups were smoking with placebo group(SP, n=14), smoking cessation with vitamins supplementatin group (SV, n=13), smoking cessation with placebo group (NSP, n=9) and smoking cessation with vitamins supplementation group (NSV, n=10). After supplementing antioxidant vitamins, significant increases were seen in plasma vitamins supplementation group (NSV, n=10). After supplementing antioxidant vitamins, significant increases were seen plasma vitamin C (p<0.05) and vitamin E levels (p<0.05). The plasma vitamin E level was highest in the NSV group. Vitmain E and C supplementation provided some protection against heme proteins and lipid damage by lowering methemoglobin, hemolysis and TBARS concentration of RBC. Smoking cessation significantly decreased TBARS of RBC and plasma total cholesterol concentration. Supplementing vitamin E and C with smoking cessation considerably lowered plasma total cholesterol. These results point to a special association among smoking, oxidative damage and plasma antioxidant vitamin status. They indicate that increases in plasma antioxidant status can be detected after the supplementation of vitamin C and E and that smoking cessation had an additional effect on plasma vitamin E level. The present data suggest that improved antioxidant status induced by antioxidant supplementation or smoking cessation may help prevent oxidative damage in smokers.

• The Journal of Korean Society for School & Community Health Education
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• v.18 no.2
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• pp.27-42
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• 2017

Objectives: The purpose of this study was to investigate the characteristics of smoking prevention programs and their effectiveness for Korean school-aged children and adolescents by using systematic review and meta-analysis. Methods: Electronic searches were performed in RISS, NAL, DBPia, KISS using keywords according to inclusion criteria. 21 studies published from 2003 to the first half of 2017 that dealt with effects of smoking prevention programs for school-aged children and adolescents were selected for systematic review. Results: All 21 studies were quasi-experimental research designs. More than half of the programs(66.7%) were conducted for male and female. Most of the programs were conducted more than once a week(71.4%). 14 studies(66.7%) did not report using a theoretical model. Five dependent variables(knowledge of smoking, attitude toward smoking, non-smoking intention, self-assertiveness, and self-efficacy) were selected to measure the effectiveness of the smoking prevention programs. Knowledge of smoking was the most effective at hedge's g=0.673. Self-efficacy and self-assertiveness variables were statistically significant at hedge's g=0.461 and hedge's g=0.279, respectively. Effect sizes of attitude toward smoking and non-smoking intention were not statistically significant compared to the control group. As a result of the moderator effect analysis on the knowledge of smoking variable, the statistically significant variables were 'gender of participants'(p<0.01) and 'duration of the program'(p<0.001). Conclusions: The results of this study using systematic review and meta-analysis will be evidence-based data for researchers conducting smoking prevention programs in school-aged children and adolescents.

• Journal of the Korean Society of School Health
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• v.20 no.1
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• pp.1-9
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• 2007

Purpose: The purpose of this study was to examine the effect of school-based preventive education on smoking-related knowledge, attitude and practice of health behaviors among elementary school children at a rural province in Korea. Methods: The subjects were 134 among the 4th -6th graders (exp. = 67, control = 67) from two schools at J province. Education program was conducted in 5-sessions for experimental group. And study instrument for smoking-related knowledge was developed 2-point 15-items (a = .82), for attitude was 3-point 15-items (a = .79), and for practice of health behavior was also 3-point 30-items (a = .86). Data were collected by interview from May 28th to July 10th 2003 and analyzed with the frequency, percentage, x2-test and t-test using SPSS-PC program, Results: The group of having smoking experiences was 14.2% and 52.2% of the subject had smoking family members. The first motive of smoking was curiosity in 78.9% and 36.8% of them started smoking before the third grade. School-based preventive education of smoking were affirmatively effective in smoking-related knowledge (t = 4.14, p = .001), smoking-related attitude (t = 3.654, p = .001), practice of health behavior, on the other hand, was not changed significantly by the education. Conclusion: Based on these findings, the authors recommend that school-based smoking prevention education should be started from lower graders in regular curricular basis and health promotion program for primary school children should be emphasized to lead healthy behavior in collaboration with public and private health sectors in community.

• Journal of Korean Academy of Nursing
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• v.29 no.6
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• pp.1192-1207
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• 1999

The purpose of this study was to clarify the dynamic relationships among risk factors of arteriosclerosis and to develop and examine a model which could explain this relationship clearly. Data were collected from medical records of 400 male clients who visited a university hospital located in Inchon for physical examinations, from May 1996 to December 1996. Data were analyzed using the LISREL (Linear Structural Relationship) 8 program. To test the fitness of the hypothesized model, chi-square, RMSR (root mean square residual), GFI (goodness of fit index), CN (critical number) and Q-plot were used. Most of the fitness measurements, except the chi-square showed that the hypothesized model complimented the real data. According to the results, there were trends that obesity and hyperlipidemia were prevalent in heavier smokers, higher alcohol intakers, and groups who excercised less. Also, hypertension was more prevalent in older age, higher alcohol intaker, and higher serum lipid level groups. In contrast to the hypothesis, alcohol intake did not significantly affect serum lipid levels. This might be due to the serum lipid measurements (total cholesterol and trigryceride) used in this study to estimate hyperlipidemia. The direct effect of smoking on hypertension was not significant. However, the total effect of smoking on the hypertension was significant since indirect effects of smoking on hypertension, such as obesity and hyperlipidemia, were significant. The total effect of obesity on hypertension was significant since the indirect effect of obesity on hypertension via hyperlipidemia was significant, although the direct effect of smoking on hypertension was not significant. The degree of explaining hyperlipidemia with smoking, exercise, and obesity was high (60%), however, the degree of explaining obesity with age, smoking, alcohol intake, and exercise was very low (7%). On the basis of these results, high risk factors of arteriosclerosis such as hypertension, hyperlipidemia, or obesity are either directly or indirectly correlated each other. Therefore, it is difficult to predict outcomes for increasing or decreasing the risk factors by simply modulating a factor. Smoking, alcohol, and exercise both directly and indirectly affected major risk factors of arteriosclerosis. Therefore, correcting these variables is required to decrease risk factors. Finally, the relationship among other risk factors which have been known to be related with arteriosclerosis (diet, stress or hereditary) should be clarified in further studies.

• Korean Journal of Adult Nursing
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• v.18 no.5
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• pp.781-789
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• 2006

Purpose: This study is to examine the effect of auricular acupressure therapy on smoking cessation for male adult in rural areas. Method: Research design was nonequivalent control pretest-posttest design. The samples were 90 male adults(Experimental: 40, Control: 40) in a community. Measures were the number of cigarette smoking per day, dependency on nicotine, and need for smoking. Auricular acupressure therapy, experimental treatment was applied for 2 weeks, 2 times/week, 3 day/time. Data were collected from June 2005 to December 2005. Data were analyzed using SPSS PC+ 12 version. Descriptive statistics, independent t-test, ${\chi}^2-test$, were used for each aim of this study. Results: The number of cigarette smoking per day (t= 13.230, p=.000), dependency on nicotine (t=-29.743, p=.000), and need for smoking (t=-19.799, p=.000) were significantly decreased in the experimental group by application of the auricular acupressure therapy. Conclusion: Auricular Acupressure Therapy can be a better effective primary nursing intervention on smoking cessation for male adults in rural areas through reverification by a study of repetition.

• Journal of Preventive Medicine and Public Health
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• v.52 no.4
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• pp.234-241
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• 2019

Objectives: To identify simultaneous behavioral changes in alcohol consumption, smoking, and weight using a fixed-effect model and to characterize their associations with disease status. Methods: This study included 7 000 529 individuals who participated in the national biennial health-screening program every 2 years from 2009 to 2016 and were aged 40 or more. We reconstructed the data into an individual-level panel dataset with 4 waves. We used a fixed-effect model for smoking, heavy alcohol drinking, and overweight. The independent variables were sex, age, lifestyle factors, insurance contribution, employment status, and disease status. Results: Becoming a high-risk drinker and losing weight were associated with initiation or resumption of smoking. Initiation or resumption of smoking and weight gain were associated with non-high-risk drinkers becoming high-risk drinkers. Smoking cessation and becoming a high-risk drinker were associated with normal-weight participants becoming overweight. Participants with newly acquired diabetes mellitus, ischemic heart disease, stroke, and cancer tended to stop smoking, discontinue high-risk drinking, and return to a normal weight. Conclusions: These results obtained using a large-scale population-based database documented interactions among lifestyle factors over time.

• Korean Journal of Health Education and Promotion
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• v.28 no.1
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• pp.49-56
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• 2011

Objectives: This study focuses on the effectiveness of a five-day target youth smoking cessation program in terms of smoking behavior, psychological characteristics, physiological changes, and 1-month maintenance of non-smoking. Methods: The participants in this one-group pre-posttest study were 91 youth smokers registered to a smoking cessation school at a hospital in Seoul. Data analyses performed include descriptive statistics, x2-test, paired t-test, and ANOVA. Results: A five-day smoking cessation program significantly decreased expired carbon monoxide level, stress, and depression. In post-intervention urine test, urine cotinine was detected in 14 of 91 participants(15.4%). In a one-month follow-up telephone survey 80.2% responded maintaining non-smoking. Conclusion: This study demonstrated the effect of a five-day smoking cessation program for adolescent smokers.

• Korean Journal of Health Education and Promotion
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• v.20 no.4
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• pp.111-127
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• 2003

The government of Korea enacted the National Health Promotion Act in 1995, and set aside funds for national health promotion, endeavoring to reduce the smoking rate of its citizens. Consequently, smoking rates in all age groups of both sexes were lowered during the period of 1999-2003 when legal backing and financial support for no-smoking policies from the national health promotion funds were provided. The decrease in the smoking rate is attributed to the combined effort of the fact that enactment of related acts, their implementation, financial support, and education and publicity 'campaigns on no smoking. However, at the current pace of decreasing the smoking rates, it will be difficult to achieve the Health and Welfare Ministry's smoking rate goal of30％ among adult males by 2013. Thus, related acts should be reshaped, corresponding support should be increased, and financial support should also be provided to implement comprehensive no-smoking policies. Also, budgets should also be alloted to establish a system of providing feedback on the monitoring and evaluation of both short-term and long-term no-smoking business planning and implementation.