• 대한의생명과학회지
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• 제26권2호
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• pp.101-108
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• 2020

There has been a lot of interest in medicinal effects for hyperlipidemia from the natural product since the therapy of atherosclerosis has emerged as social concern. Rats were acclimated to the feeding environment for one week and induced to obesity with high fat diet during 4 weeks until their body weight were more than 30% of normal range. To evaluate the effect of hyperlipidemia of mulberry leaf of Morus alba and yacon tuber of Smallanthus sonchifolia extracts (MLYT), 1%, 3%, 5% of MLYT were treated to Sprague-Dawley rats. Aspartate transaminase (AST) was significantly increased 26.2% in high fat diet group (G2) compared to normal diet group (G1) (P<0.05). But AST were significantly decreased in high fat diet with 0.5% hydroxycitric acid diet group (G3) and all the MLYT treated groups compared to G2. Total cholesterol, low-density lipoprotein (LDL), triglycerides and phospholipids were observed significant improvements in the MLYT-treated groups (P<0.05). These improvements in liver and feces were further supported by the lipid content. MLYT remarkably suppressed the level of lipid peroxidation caused by high-fat diet in rats. The level of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase activity. As a result, the proper combination of mulberry leaves and yacon tuber extract will have a synergistic effect on hyperlipidemia. These results indicate that MLYT could be a candidate for the improvement of hyperlipidemia.

• 대한의생명과학회지
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• 제26권2호
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• pp.75-84
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• 2020

We evaluated the effect of anti-obesitic activity of MYE (mulberry leaf + Yacon tuber) extracted from Morus alba as muberry leaf and Smallanthus sonchifolia as yacon. 1%, 3%, or 5% of MYE were treated to Sprague-Dawley rats exposed to a high-fat diet. MYE treated rats were suppressed weight during four weeks, and they lost weight significantly after six weeks. Common blood chemistry panels related to liver function revealed significant improvement in the MYE-treated groups. The expression of leptin as indicators for obesity was decreased in perirenal fat. Such results indicate that MYE could be a promising candidate for the improvement of obesity. In addition, MYE effected on deceased glucose metabolism, reducing the activities of glucose-6-phosphate dehydrogenase (G-6-PDH) and glucokinase related to glycogen synthesis. The fatty liver was observed in high-fat diet-treated rats, resulting from increased number of adipose cells and Ito cells. However, this pathologic change was significantly improved by administration of MYE. MYE have significant effects on antioxdative function and glycometabolism against high fat diet. Thereby, it seems that MYE prevent fatty liver by high-fat diet. Thus it is suggested that MYE would be worth being developed as an biofunctional food to prevent undesirable effects caused by obesity.

• 한국조리학회지
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• 제20권3호
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• pp.100-112
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• 2014

야콘을 첨가한 쿠키를 제조하여 특성을 조사하였다. 야콘 가루 첨가 쿠키는 밀도간에 영향을 미치지 않았으며 pH는 야콘 가루 첨가량이 증가할수록 감소하였다 야콘 가루 12% 첨가군이 가장 높은 수분함량을 보였다. 대조군보다 야콘 가루 첨가군의 퍼짐성이 더 높았으며 손실률과 팽창률은 대조군이 높았으며 전반적으로 야콘 가루를 첨가할수록 퍼짐성은 증가하고 손실률과 팽창률은 감소하는 경향을 보였다. 야콘 가루를 첨가할수록 쿠키의 색도는 명도 L값과 황색도 b값은 낮아지고 적색도 a값은 증가하는 경향을 보였다. 야콘 가루 3%와 6% 첨가군은 대조군과 유의적인 차이가 없었으나 야콘 가루 9%와 12% 첨가군은 대조군보다 낮은 경도 값을 보였다. 이는 야콘 가루를 첨가할수록 수분함량이 높았으므로 수분함량 차이로 인해 경도가 낮아진 것으로 사료된다. 야콘 가루 첨가 쿠키의 DPPH 라디칼 소거능에 대한 결과는 야콘 가루 첨가량이 많을수록 DPPH 라디칼 소거능이 증가하여 12% 첨가군이 가장 높았다. 외관의 기호도는 대조군과 야콘 가루 3%, 6% 첨가군을 선호하였으며 야콘 6% 첨가군이 가장 높은 기호도를 보여 시료간의 유의적인 차이가 있었다. 맛의 기호도는 야콘 가루 6% 첨가군, 3% 첨가군 순으로 높게 나타났으며, 전반적인 기호도에서 6% 첨가군이 높은 기호도를 보였다. 이상의 결과에서 가루에 야콘 분말을 첨가하면 쿠키의 물성이나 기호도 등에서 좋은 영향을 주는 것으로 나타나 항산화성과 관능적 평가에서 6% 정도 첨가하는 것이 가장 좋을 것으로 사료 된다. 이와 같이 본 실험을 통하여 야콘 쿠키의 건강 기능성 측면을 고려한 상품으로서의 소비자의 만족도와 제품개발 가능성을 확인 하였다.