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Nitric Oxide Inhibitory Constituents from Fruits of Opuntia humifusa

  • Kang, You-Jeng;Kim, Hae-Young;Lee, Chul;Park, So-Young
    • Natural Product Sciences
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    • v.20 no.3
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    • pp.211-215
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    • 2014

  • Opuntia humifusa, also called as Cheonnyuncho, is a cactus widely cultivated in southern regions of Korea. It has been known to have diverse biological activities, but most of the studies were performed with the MeOH extracts or solvent-partitioned fractions. Furthermore, the efforts to identify the responsible compounds for the biological activities are very limited. In this study, we tested the inhibitory effect of extracts and solvent-partitioned fractions of O. humifusa against LPS-induced nitric oxide (NO) production in Raw264.7 cells. The butanol fractions of O. humifusa efficiently inhibited the production of NO in Raw264.7 cells, but it was not due to the reduction of cell viability. Bioassay-guided isolation of butanol fractions of O. humifusa allowed the isolation of three flavonoids isorhamnetin 3-O-${\beta}$-$\small{D}$-galactosyl-4'-O-${\beta}$-$\small{D}$-glucoside (1), isorhamnetin 3,4'-di-O-${\beta}$-$\small{D}$-glucoside (2) and isorhamnetin 3-O-${\beta}$-$\small{D}$-(6-O-${\alpha}$-$\small{L}$-rhamnosyl)glucoside (3), and one lignan syringaresinol O-${\beta}$-$\small{D}$-glucopyranoside (4). Among them, isorhamnetin 3-O-${\beta}$-$\small{D}$-galactosyl-4'-O-${\beta}$-$\small{D}$-glucoside (1) and isorhamnetin 3,4'-di-O-${\beta}$-$\small{D}$-glucoside (2) exhibited the moderate inhibitory effects against LPS-induced NO production. This is the first time to report anti-inflammatory effects of these compounds.

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A study on the sled test methods for IIHS small overlap performance development (IIHS small overlap 성능개발을 위한 대차 시험 방법 연구)

  • Oh, Hyungjooon;Kim, Seungki;Kim, Sungwon;Lim, Kyungho
    • Journal of Auto-vehicle Safety Association
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    • v.5 no.1
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    • pp.11-15
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    • 2013

  • Small overlap crash caused fatal injury in real-world crash. IIHS(Insurance Institute for Highway Safety) proposed the small overlap test. The objective of this study is to analyze dummy injury criteria and dummy excursion on the sled reinforced body angle. Result of the comparisons of dummy injury criteria of a head, neck, and chest was best correlation between sled and vehicle test on base $angle+3^{\circ}$. However, lower extremity was not correlation because sled test could not copy of intrusion. There were a correlation between dummy movement and sled reinforced body angle. Sled reinforced body angle affects the lateral direction of excursion more than longitudinal excursion.

  • https://doi.org/10.22680/kasa.2013.5.1.011 인용 PDF

Status and Prospects of Farm Mechanization in China

  • Guozhu, Hua
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1993.10a
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    • pp.87-97
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    • 1993

  • China has a big population(22% of the world) and small cultivated land( only 7% of the world). Agriculture is very important and it has solved the problem of people's eating and wearing, and now it is creating favourable conditions for the state modernization and people's comparatively well-off. Farm mechanization plays an role in agriculture and has primarily developed. But the development is complicated since the big rural labour force and the small per capita cultivated land. The development and features of farm mechanization in China was summarized and the future task and its countermeasure was discussed in this paper.

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