• Journal of Pharmaceutical Investigation
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• v.36 no.2
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• pp.97-102
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• 2006

The aim of this study was to investigate the feasibility and optimize permeability of slim patch type as a transdermal delivery system of caffein. Slim patch type was formulated and tested in modified Franz diffusion cell across cellulose membrane and hairless mouse skin in pH 5.8 phosphate buffer solution (PBS). The effect of $Pharmsolv^{\circledR}$ and drug concentration on permeation at four model, 1,2% $Pharmsolv^{\circledR}$ with $0.12\;mg/cm^2$ caffein and 0.12, $1.2\;mg/cm^2$ caffein with 2% $Pharmsolv^{\circledR}$ through hairless mouse skin was studied in vitro. The release of caffein from slim patch with various loading was fitted by the Higuchi's diffusion equation. The result showed that chemical $Pharmsolv^{\circledR}$ produced a large and significant increase of permeation. The effect of 2% $Pharmsolv^{\circledR}$ on permeation of caffein was greater about 10-fold greater than 1% $Pharmsolv^{\circledR}$ in first 60 minutes. The effect of drug concentration, however, was lower than that produced by chemical $Pharmsolv^{\circledR}$. Within the tested system, the most efficient combination for caffein slim patch type was $0.12\;mg/cm^2$ caffein with 2% $Pharmsolv^{\circledR},$ although $1.2\;mg/cm^2$ caffein with 2% $Pharmsolv^{\circledR}$ showed highest amounts permeation, because permeated percentages were significantly lower about $1/4{\sim}1/5$ times.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.14 no.8
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• pp.855-862
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• 2003

This paper suggests the PIFA structure modified antenna in which short-circuit plate is located between planar element and ground plane, in order to solve the problem of narrow band of existing internal antenna, PIFA. It is also suggested that internal antenna has the perturbation in the patch to broaden the frequency bandwidth. It is possible that the antenna is installed into the mobile telephone with a low profile condition(h=0.015 λ) to use internally, and acquired desired bandwidth(5.2 %) through double resonance structure, remodeling the PIFA that is already well-known as an internal antenna. This paper investigated how characteristic is affected by the feeding point(Yf, Zf), short strip plate(Zs), short strip width(Ws), perturbation width(w), length(d), short plate height(h), dielectric($\varepsilon$$\_$r/) to be slim type antenna. It is compared with existing PIFA bandwidth, and is suggested pattern as the H.E plane. It is simulated using the Microwave Studio of the CST Inc. based on FIM(Finite Integration Method) method and analyzed antenna characteristic following the variation each parameters. The result proved the practical use of PIFA antenna by comparing the measured and simulated data of the antenna.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.9
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• pp.978-984
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• 2008

In this paper, we propose a RFID metal tag antenna with a minimum by size of a metal surface to attach. This proposed tag antenna is a patch antenna which is able to stick on metal surface and designed for very slim structure ($119{\times}30{\times}1.6$ mm) antenna that is matched to a chip impedance. This has a loop coupling feeding and consists of a inner radiator and a outer radiator. The outer radiator activates the current to concentrate on the inner radiator regardless of metal size to attach. Also the tag antenna is designed by CST microwave tool and the performance is measured in the anechoic chamber. The optimum antenna has 3.77 % of the matching bandwidth($S_{11}<-10$ dB). The readable range of the tag antenna is about 2.9 m on metal(max. size $700{\times}700$ mm) and 5.5 m in free space according to the measurement results.