• 수면정신생리
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• 제28권2호
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• pp.70-77
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• 2021

목 적 : 본 연구의 목적은 불면증 환자의 주관적 수면인식과 관련 있는 임상적, 객관적 요인들을 알아보고 임상에서 불면증 환자의 이해와 평가 및 치료에 도움을 주기 위함이다. 방 법 : 109명의 불면증 환자들을 대상으로, 수면다원검사 결과와 자가보고 설문지를 후향적으로 분석하였다. 주관적 수면인식은 아침자가보고 설문지의 주관적 총 수면시간(subjective total sleep time, subjective TST), 입면 잠복시간(subjective sleep onset time; subjective SOL), 각성횟수, 아침 개운함 정도로 측정하였으며, 주관적-객관적 수면차이를 계산하였다. 임상적 특징은 Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory (BDI), Epworth Sleepiness Scale (ESS)를 측정하였다. 변수들 사이의 관련성을 알아보기 위하여 상관분석을 시행하였다. 결 과 : 109명의 불면증 대상자(남성 = 72명, 나이 43.49 ± 15.32세)를 분석한 결과, 주관적 총 수면시간(subjective TST)은 수면다원검사에서의 입면 후 각성시간(wake after sleep onset, WASO) (p < 0.001), N1 수면(p = 0.039), PSQI (p < 0.001), BDI (p = 0.014)와 유의한 음의 상관관계를 보였다. 수면차이는 PSQI (p = 0.018)와 유의한 음의 상관관계가 있었다. 아침 개운함 정도는 PSQI (p = 0.019), BDI (p < 0.001)와 유의한 음의 상관관계가 있었다. 결 론 : 불면증 환자에서 주관적 수면인식은 수면다원검사의 입면 후 각성시간(WASO), N1 수면과 관련성이 있었으며, 우울감과 평소 수면의 질과 관련성이 있었다. 불면증 환자에서 다양한 객관적 수면변수, 평소 수면의 질 및 우울감이 주관적 수면인식에 영향을 미치므로, 이를 고려하여 환자를 평가 및 치료해야 하겠다.

• 성인간호학회지
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• 제20권3호
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• pp.365-374
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• 2008

Purpose: This study was conducted to evaluate quality of sleep and to assess the factors that influence quality of sleep in surgical ICU. Methods: The subject of the study were consisted 109 adult patients who admitted to surgical ICU. The data were collected from May 20 to December 10, 2007 by structured questionnaires. The data were analyzed with descriptive analysis, paired t-test, Pearson correlation coefficient and stepwise multiple regression. Results: The score of quality of sleep was 4.57 point. The main sleep disturbance factors related to quality of sleep in surgical ICU inpatient were sleep time, machinery alarm and noise(adjusted $R^2$=33.2). Conclusion: Based on the finding of this study, it is needed to develop a nursing intervention program that including to promote quality of sleep and to decrease machinery alarm and noise in surgical ICU.

• 한국멀티미디어학회논문지
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• 제22권12호
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• pp.1491-1499
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• 2019

Insufficient sleep time and bad sleep quality causes many illnesses and it's research became more and more important. The most common method for measuring sleep quality is the polysomnography(PSG). The PSG is a test used to diagnose sleep disorders. The most common PSG data is obtained from the examiner, which attaches several sensors on a body and takes sleep overnight. However, most of the sleep stage classification in PSG are low accuracy of the classification. In this paper, we have studied algorithm for sleep level classification based on machine learning which can replace PSG. EEG, EOG, and EMG channel signals are studied and tested by using CNN algorithm. In order to compensate the performance, a mixed model using both CNN and DNN models is designed and tested for performance.

• International Journal of Advanced Culture Technology
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• 제10권3호
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• pp.47-56
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• 2022

The purpose of this study is investigate the effects of quality of life and occupational performance on quality of sleep in college students. Data had been collected from Sep. 1 to Sep. 30, 2021. The subjects of this study were students majoring in occupational therapy at C College situated in C region. For analysis, 103 copies of questionnaire were used. As study instruments, a structured questionnaire incorporating questions about general characteristics, and measurement scales for quality of life, quality of sleep, and occupational performance evaluation were applied. Subjective sleep quality and sleep latency of study participants had lower scores than other components. According to the analysis on different quality of sleep depending on general characteristics, women had more sleep disturbances as they didn't have any part-time job. In terms of the correlation between quality of sleep and quality of life, physical health and total score (quality of life) had correlations with daytime dysfunction. With regard to influential factors on quality of sleep, rest & sleep as a domain of occupational performance and work affected quality of sleep. Students' quality of sleep will be improved if they keep regular habits of living, have rest appropriately for alleviating their stress, and do their jobs with interest and successfully according to a procedure. It is expected that the results of this study will be helpful to care for the health of would-be experts in charge of national health care.

• 수면정신생리
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• 제29권2호
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• pp.40-44
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• 2022

Bipolar disorders are a group of mood disorders characterised by relapsing mood episodes throughout the course of illness. Patients with bipolar disorders commonly present with various sleep problems. Patients in a manic episode generally show decreased need of sleep and those in a depressed episode frequently complain about hypersomnia. Current literature even points to evidence that patients with bipolar disorder in euthymic state may still show signs of sleep disturbances when compared to the general population. Clinicians may also note intricate interactions between changes of circadian rhythm and evolution of mood episodes in patients with bipolar disorder. Also, commonly prescribed medications which plays a crucial role in treatment of bipolar disorders including mood stabilisers and antipsychotic medications often cause significant weight gain over time. Being a risk factor of sleep apnoea, weight gain can predispose the patient to develop sleep apnoea. In this narrative review, we summarised current evidence and literature regarding characteristics of circadian rhythm and comorbid sleep apnoea in patients with bipolar disorder. We also present literature regarding implications of circadian disturbance and comorbid sleep apnoea in managing patients with bipolar disorder.

• Natural Product Sciences
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• 제15권4호
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• pp.213-221
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• 2009

Longanae Arillus (the rind of fruits of Dimocarpus longan) has been consumed for the treatment of insomnia and anxiety in Asia. To provide further scientific basis to traditional uses of this fruit on insomnia, we evaluated the effects of methanol extract of Longanae Arillus (MELA) on the alteration of sleep architecture and electroencephalogram (EEG) power spectra in acutely and chronically restraint-stressed rats. Following postsurgical recovery, Polygraphic signs of sleep-wake activities were recorded for 24 h after MELA administration in rats. Rats in the acute stress and chronic stress were administered with MELA for 10 days. On the $8^{th},\;9^{th}\;and\;10^{th}$ day of MELA administration, the rats were stressed for 3 h once per day. On the $10^{th}$ day and 1 h after MELA administration, the rats were stressed once for 22 h in the chronic stress group. Acute and chronic stress induced alternations in cortex EEG recordings during non-rapid eye movement (NREM), rapid eye movement (REM) sleep and wakefulness. MELA shortened the total and REM sleep and increased the wakefulness in night time recording without changing daytime recordings. Chronic stress increased wakefulness and REM sleep, decreased total and NREM sleep in the daytime recording, and increased REM and decreased NREM sleep without changing total sleep and wakefulness in night time recording. These findings suggest that MELA ameliorated the alterations in REM and NREM sleep of acutely and chronically stressed rats via modulation of cortical ${\alpha}-$, ${\theta}-$ and ${\delta}-$ wave activity.

• 대한의용생체공학회:의공학회지
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• 제36권5호
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• pp.204-210
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• 2015

Although many studies have analyzed the relationship between electrodermal activity (EDA) and sleep stages, a practical method for detecting sleep stage using EDA has not been suggested. The aim of this study was to develop an algorithm for real-time automatic detection of deep sleep using the EDA signal. Simultaneously with overnight polysomnography (PSG), continuous measurement of skin conductance on the fingers was performed for ten subjects. The morphometric characteristics in the fluctuations of EDA signal were employed to establish the quantitative criteria for determining deep sleep. The 30-sec epoch-by-epoch comparison between the deep sleep detected by our method and that reported from PSG exhibited an average sensitivity of 74.6%, an average specificity of 98.0%, and an average accuracy of 96.1%. This study may address the growing need for a reliable and simple measure for identifying sleep stage without a PSG.

• Biomolecules & Therapeutics
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• 제25권2호
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• pp.105-111
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• 2017

It has been known that RA, one of major constituents of Perilla frutescens which has been used as a traditional folk remedy for sedation in oriental countries, shows the anxiolytic-like and sedative effects. This study was performed to know whether RA may enhance pentobarbital-induced sleep through ${\gamma}-aminobutyric$ acid $(GABA)_A-ergic$ systems in rodents. RA (0.5, 1.0 and 2.0 mg/kg, p.o.) reduced the locomotor activity in mice. RA decreased sleep latency and increased the total sleep time in pentobarbital (42 mg/kg, i.p.)-induced sleeping mice. RA also increased sleeping time and number of falling sleep mice after treatment with sub-hypnotic pentobarbital (28 mg/kg, i.p.). In electroencephalogram (EEG) recording, RA (2.0 mg/kg) not only decreased the counts of sleep/wake cycles and REM sleep, but also increased the total and NREM sleep in rats. The power density of NREM sleep showed the increase in ${\delta}-waves$ and the decrease in ${\alpha}-waves$. On the other hand, RA (0.1, 1.0 and $10{\mu}g/ml$) increased intracellular $Cl^-$ influx in the primary cultured hypothalamic cells of rats. RA (p.o.) increased the protein expression of glutamic acid decarboxylase ($GAD_{65/67}$) and $GABA_A$ receptors subunits except ${\beta}1$ subunit. In conclusion, RA augmented pentobarbital-induced sleeping behaviors through $GABA_A-ergic$ transmission. Thus, it is suggested that RA may be useful for the treatment of insomnia.

• 기본간호학회지
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• 제6권2호
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• pp.198-210
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• 1999

This study is to investigate sleep patterns of rheumatoid arthritis patients through a survey research. The subjects for this study were 97 patients registered in Hanyang University Hospital Rheumatoid Arthritis Center, and the period of data collection was from July 15, 1998 to August 30, 1998. The research instruments used in this study were the measures of sleep, pain, and fatigue, and SPSSWIN 8.0 Program was used for data analysis. The research results are as follows ; The patients went to bed between 11 and 12 p.m., but many of them found difficulty in falling asleep within 5 minutes. They woke up quite early at around 4 to 6 o'clock in the morning and remained in bed about 1 hour. Only 39 percent of the subjects reported satisfaction with their sleep. Fifty six percent of the subjects took a nap, generally did in the afternoon and 22.7 percent of them napped for half an hour. They suffered sleep disturbance, but their sleep environments were calm and comfortable, and they turn off the light when they went to sleep. As for the quality of sleep, over 50 percent of the subjects reported not being able to sleep deeply, 30 percent of the subjects woke up frequently during sleep, 60 percent experienced frequent arousal after sleep onset. Over 90 subjects slept for 6 to 8 hours. This shows that even though they had rheumatoid arthritis, the patients remained in bed for a sufficient period of time. They also reported waking up or turning frequently during sleep. The sense of fatigue from sleep disturbance scored a relatively high 35.84 points on average against the possible score of 64 points. Behavior for sleep promotion was very active. Sleep disturbance occurred in proportion to the sense of fatigue and pain, and was negatively correlated with quality of sleep. The pain had positive correlations with the illness duration, sleep disturbance and had a negative correlation with the quality of sleep.

• Child Health Nursing Research
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• 제5권3호
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• pp.281-291
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• 1999

The purpose of this study was to compare the sleep characteristics between the prone and the supine position in healthy newborns. The 48 newborns were observed in the prone position and the supine position respectively on the 2nd day after birth. The data were collected from January to May, 1999. The state of a newborn was classified and categorized to 6 states (deep sleep. light sleep, drowsy, quiet alert, active alert, crying) by Barnard. The movements of eyes, face and extremities, pulse and arterial oxygen were observed and recorded continuously from the start of sleep after feeding until the time of being woken for the next feeding by a trained nurse The data was analyzed by using paired t-test. The results of this study were as follows; 1. There was no significant difference in the length of sleeping time between the prone and the supine position. 2. There was no significant difference in the length and frequencies of each states(deep sleep, light sleep, drowsy, quiet alert, active alert, crying) between the prone and the supine position But the frequency of light sleep in the supine position was significantly higher than that of the prone position. 3 There was no significant difference In the numbers or eyes movements between the prone and the supine sleep position. But the amount of facial and extremity movement in the supine position was significantly higher than those in the prone position 4. There was no significant difference in the arterial oxygen content between the prone and the supine sleep position. 5. There was no significant difference in the heart rates between the prone and the supine sleep position. The above results indicated that the newborns in the prone Position moved less and slept deeper than those in the supine position. though there was no difference in the length of sleep or arterial oxygen content between the prone and the supine sleep Position. But. Nurses and mothers should consider the relationship between the sleep Position and SIDS suggested by previous researches. The infant's 'awakening' during sleep is a normal process and rather valuable because it can provide an opportunity to promote a stronger relationship between mother and baby. So, It is suggested that the supine sleep position is better than the prone sleep position for infants.