• 대한의용생체공학회:의공학회지
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• 제36권5호
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• pp.204-210
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• 2015

Although many studies have analyzed the relationship between electrodermal activity (EDA) and sleep stages, a practical method for detecting sleep stage using EDA has not been suggested. The aim of this study was to develop an algorithm for real-time automatic detection of deep sleep using the EDA signal. Simultaneously with overnight polysomnography (PSG), continuous measurement of skin conductance on the fingers was performed for ten subjects. The morphometric characteristics in the fluctuations of EDA signal were employed to establish the quantitative criteria for determining deep sleep. The 30-sec epoch-by-epoch comparison between the deep sleep detected by our method and that reported from PSG exhibited an average sensitivity of 74.6%, an average specificity of 98.0%, and an average accuracy of 96.1%. This study may address the growing need for a reliable and simple measure for identifying sleep stage without a PSG.

• 대한의용생체공학회:의공학회지
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• 제34권2호
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• pp.97-103
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• 2013

This paper proposes a new algorithm for sleep apnea detection based on stroke volume. It is very important to detect sleep apnea since it is a common and serious sleep-disordered breathing (SDB). In the previous studies, methods for sleep apnea detection using heart rate variability, airflow and blood oxygen saturation, tracheal sound have been proposed, but a method using stroke volume has not been studied. The proposed algorithm consists of detection of characteristic points in continuous blood pressure signal, estimation of stroke volume and detection of sleep apnea. To evaluate the performance of algorithm, the MIT-BIH Polysomnographic Database provided by Phsio- Net was used. As a result, the sensitivity of 85.99%, the specificity of 72.69%, and the accuracy of 84.34%, on the average were obtained. The proposed method showed comparable or higher performance compared with previous methods.

• 대한의용생체공학회:의공학회지
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• 제34권3호
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• pp.105-110
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• 2013

Respiratory signal is one of the important physiological information indicating the status and function of the body. Recent studies have provided the possibility of being able to estimate the respiratory signal by using a change of PWV(pulse width variability), PRV(pulse rate variability) and PAV(pulse amplitude variability) in the PPG (photoplethysmography) signal during daily life. But, it is not clear whether the respiratory monitoring is possible even during sleep. Therefore, in this paper, we estimated the respiration from PWV, PRV and PAV of PPG signals during sleep. In addition, respiration rates of the estimated respiration signal were calculated through a time-frequency analysis, and errors between respiration rates calculated from each parameter and from reference signal were evaluated in terms of 1 sec, 10 sec and 1 min. As a result, it showed the errors in PWV(1s: $36.38{\pm}37.69$ mHz, 10s: $36.53{\pm}38.16$ mHz, 60s: $30.35{\pm}38.72$ mHz), in PRV(1s: $1.45{\pm}1.38$ mHz, 10s: $1.44{\pm}1.37$ mHz, 60s: $0.45{\pm}0.56$ mHz), and in PAV(1s: $1.05{\pm}0.81$ mHz, 10s: $1.05{\pm}0.79$ mHz, 60s: $0.56{\pm}0.93$ mHz). The errors in PRV and PAV are lower than that of PWV. Finally, we concluded that PRV and PAV are more effective than PWV in monitoring the respiration in daily life as well as during sleep.

• 한국멀티미디어학회논문지
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• 제21권12호
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• pp.1370-1378
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• 2018

There is a problem to measure neutral bio-signals during sleep because of inconvenience of attaching lots of sensors. In this study, we measured single electrocardiogram(ECG) signal and analyzed the correlation with sleep. After R-peak detection from ECG signal, we extracted 9 features from time and frequency domain of heart rate variability(HRV). Mean of HRV, RR intervals differing more than 50ms(NN50), and divided by the total number of all RR intervals(pNN50) have significant differences in each sleep stage. Specially, the mean HRV has an average of 87.8% accuracy in classifying sleep and awake status. In the future, the measurement ECG signal minimizes inconvenience of attaching sensors during sleep. Also, it can be substituted for the standard sleep measurement method.

• 대한의용생체공학회:의공학회지
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• 제36권5호
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• pp.143-149
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• 2015

In this paper, we proposed a novel method for automatic detection for snoring and heart beat using a single piezoelectric sensor. For this study multi-rate signal processing technique was applied to detect snoring and heart beat from the single source signal. The sound event duration and intensity features were used to snore detection and heart beat was found by autocorrelation. The performance of the proposed method was evaluated on clinical database, which is the nocturnal piezoelectric snoring data of 30 patients that suffered obstructive sleep apnea. The method achieved sensitivity of 88.6%, specificity of 96.1% with accuracy of 95.6% for snoring and sensitivity of 94.1% and positive predictive value of 87.6% for heart beat, respectively. These results suggest that the proposed method can be a useful tool in sleep monitoring and sleep disordered breathing diagnosis.

• 대한의용생체공학회:의공학회지
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• 제38권4호
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• pp.153-162
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• 2017

The present study proposes a system that can detect sleep-disordered breathing automatically using an air mattress and oxygen saturation. A thin air mattress was fabricated to reduce discomfort during sleep, and respiration signals were acquired. The system was configured to be synchronized with a polysomnography to receive signals simultaneously with other bio-signals. The present study has been conducted with nine adult male and female patients with sleep-disordered breathing, and sleep-disordered breathing events have been detected by applying the signals acquired from the subjects to the rule-based detection algorithm. The sensitivity and positive predictive values were found to evaluate the performance of the system, which are 91.4% and 89.7% for all events, respectively. The comparison of apnea hypopnea index(AHI) between the polysomnography and the proposed method showed squared R-value of 0.9. This study presents the possibility of detecting sleep-disordered breathing at hospitals or homes using the proposed system.

• 한국멀티미디어학회논문지
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• 제21권5호
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• pp.609-616
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• 2018

In this paper, we designed a multimodal bio-signal measurement system to observe changes in the brain nervous system and vascular system during sleep. Changes in the nervous system and the cerebral blood flow system in the brain during sleep induce a unique correlation between the changes in the nervous system and the blood flow system. Therefore, it is necessary to simultaneously observe changes in the brain nervous system and changes in the blood flow system to observe the sleep state. To measure the change of the nervous system, EEG, EOG and EMG signal used for the sleep stage analysis were designed. We designed a system for measuring cerebral blood flow changes using functional near-infrared spectroscopy. Among the various imaging methods to measure blood flow and metabolism, it is easy to measure simultaneously with EEG signal and it can be easily designed for miniaturization of equipment. The sleep stage was analyzed by the measured data, and the change of the cerebral blood flow was confirmed by the change of the sleep stage.

• 대한의용생체공학회:의공학회지
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• 제38권5호
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• pp.264-270
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• 2017

A Doppler radar sensor was applied to detect respirations and heartbeats of persons who were lying on a bed. This study is preliminary study aiming at non-contact and non-intrusive respiration and heart rate monitoring during sleep in daily life. For the experiments, 10GHz Doppler radar with patch-type antenna was used and installed on the upper right and the distance between the body and the antenna was 1 m. The results show that each signal of respiration and heartbeat is observed in each frequency band however the frequency band and the waveform vary according to the subjects and the posture. The results show that the heartbeats can be detected with the peak detection in some frequency band. This study shows the feasibility of applying the Doppler radar to detection of heartbeat and respiration during sleep and further studies about heartbeat detection algorithm are required.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2008년도 하계종합학술대회
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• pp.1101-1102
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• 2008

In this paper, we have developed PPG pillow system for unconstrained respiration monitoring during sleep. The system employs a pillow containing a PPG sensor and a simple respiration extraction algorithm. The results showed that the extracted respiratory rhythm was found to have close relations with the reference signal. The system has an advantage of processing simplicity. A follow-up study should be performed to evaluate the system in terms of breath intake.

• 융합신호처리학회논문지
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• 제20권2호
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• pp.105-110
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• 2019

사람들은 일생동안 1/3을 잠을 자며 그들의 잠자는 시간은 나이에 따라 변하게 된다. 일반적으로 어른들은 하루에 8시간의 잠을 잔다. 그러나 항상 좋은 잠자리를 기대할 수는 없다. 실제로 50대 이상의 많은 사람들은 수면 문제를 가지고 있다. 이는 코골이, 수면 무호흡과 같은 수면 장애요소들 때문에 발생하는 것이다. 이 논문에서는 수면 장애요소 중 하나인 코골이를 검출하는 스마트 베개에 대해서 조사하였다. 스마트 베개는 베개의 오른쪽과 왼쪽 부분에 위치한 두 개의 마이크로폰으로 구성되어져 있다. 쉽게 코골이는 검출하기 위하여 피크 검출회로를 사용하여 코골이 신호를 펄스신호로 변형시켰으며, 펄스폭을 사용하여 코골이 이벤트 발생을 판단하였다. 측정된 코골이 검출 정확도는 약 98.6%이었다. 본 연구에서 얻은 연구 결과들이 스마트 베개가 수면 중 코골이를 검출할 수 있음을 보여 주었다.