• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.2
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• pp.94-98
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• 2004

A female sixty years old visited the Dept. of Oriental Medical Ophthalmology & Otolaryngology & Dermatology Hospital, Dong-eui University with contact dermatitis. she was suffering from the topical itching, empalement, ruler, edema and vesicle etc in skin of the face and two dorsum manus. We treated a patient with only Oriental Medicine.(internal and external use of the herbal medicine and acupuncture) After two weeks or so, the symptom of the skin disease recovered remarkably, we think that this is good case to treat with Oriental Medicine.

• The Journal of Internal Korean Medicine
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• v.24 no.2
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• pp.402-408
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• 2003

Exfoliative dermatitis is a name of a group of symptoms which is characterized by red rash, itching and scale in almost whole body. The patients are suffered from hypoalbuminemia, general weakness and fever sign in addition to characteristic skin lesions. So in the treatment of this disease, adequate symptomatic treatment is important with adequate topical skin management. We experienced a 67 year old Korean male patient diagnosed as exfoliative dermatitis based on clinical symptoms. We concluded that the symptoms of this patient are Sun-symptoms(癬症) and gave him Sunpunghwangi-san(宣風換肌散) and Chungdae-san(靑黛散). After taking herbal medicine, clinical improvement was noticed. Based on this experience, both internal and external use of oriental medicine have a good effect on exfoliative dermatitis.

• IMMUNE NETWORK
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• v.22 no.2
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• pp.20.1-20.9
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• 2022

Despite the high prevalence of chronic dermatitis and the accompanied intractable itch, therapeutics that specifically target itching have low efficacy. Increasing evidence suggests that TLRs contribute to immune activation and neural sensitization; however, their roles in chronic itch remain elusive. Here, we show that the RBL-2H3 mast cell line expresses TLR4 and that treatment with a TLR4 antagonist opposes the LPS dependent increase in mRNA levels of Th2 and innate cytokines. The pathological role of TLR4 activation in itching was studied in neonate rats that developed chronic itch due to neuronal damage after receiving subcutaneous capsaicin injections. Treatment with a TLR4 antagonist protected these rats with chronic itch against scratching behavior and chronic dermatitis. TLR4 antagonist treatment also restored the density of cutaneous nerve fibers and inhibited the histopathological changes that are associated with mast cell activation after capsaicin injection. Additionally, the expression of IL-1β, IL-4, IL-5, IL-10, and IL-13 mRNA in the lesional skin decreased after TLR4 antagonist treatment. Based on these data, we propose that inhibiting TLR4 alleviated itch in a rat model of chronic relapsing itch, and the reduction in the itch was associated with TLR4 signaling in mast cells and nerve fibers.

• Journal of Korean Medical Ki-Gong Academy
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• v.18 no.1
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• pp.113-145
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• 2018

Objective : The purpose of this study is to report about a mid-40's female patient with Prurigo Nodularis, whose symptoms were relieved after Korean medicine treatment alone with Whidam's Su-Gi Therapy. Methods : the patient in this study received only Korean medicine treatment such as herbal medication, acupuncture treatment, cupping therapy and specially Whidam's Su-Gi therapy. Results : After the treatment, the symptoms of Prurigo Nodularis were relieved. Contact Itching Index fell from 10 to 5, and Non-Contact Itching Index fell from 10 to 4. On the whole the Body Heat has risen and skin condition has improved visually. The significance of Meridian Function Check(based on HRV) and skin syndrome is remarkable., Conclusions : This study showed that Whidam's Su-Gi therapy added with Korean Medicine treatment can be an effective choice for Prurigo Nodularis. So, wasting disease, especially immune-reduced syndrome such as Prurigo Nodularis, may also be treated with Korean Medicine alone without side effects.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.230-242
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• 2014

Objective : The purpose of this study is to report the Korean medicine treatment on Pustulosis Palmaris et Plataris with Extra-Palmoplantar lesions. Method : We adopted herbal medicine(Seungchung-tang-1, Eunjin-1), acupuncture and vapor treatment to treat Pustulosis Palmaris et Plantaris with Extra-Palmoplantar lesions. Steroids were administered for preventing aggravation. We observed patient's hot sensation, itching and pain of both hands and patient's itching and pain of both feet with the Visual Analogue scale(VAS). Also photographs were taken for judging inflammatory skin. Result : After the treatment, the grade of VAS was decreased from 10 to 0 and clinical symptoms were resolved. By judging photographs patient's inflammatory skin was cured. Administered steroid were also reduced from 15 mg per day to 0. Conclusion : This study shows that the Korean medicine treatment was effective to treat Pustulosis Palmaris et Plataris with Extra-Palmoplantar lesions and enable to stop steroid therapy.

• The Korea Journal of Herbology
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• v.32 no.3
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• pp.89-95
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• 2017

Objectives : Seborrheic dermatitis is common abnormal skin condition characterized by flaking and itch. In seborrheic dermatitis, the flakes are greasy and yellowish. Inflammation is also observed. Through this paper we can understand the process of seborrheic dermatitis of the scalp and confirm the scalp changes in the treatment process. The purpose of this study was to report the clinical effects of herbal medicine on Seborrheic dermatitis Methods : We employed oriental medical treatments; herbal-medication (Hyeongbangpaedoksangamibang), infant acupuncture, moxibustion and blood therapy. We treated her three times a week. She took medicine three times a day after a meal. During taking medicine, we let her avoid fatty food, flour based food. Her father took a picture the patient's head parts and we compared the symptom with previous symptom. With the picture, we evaluated the patient's scalp condition. Results : After taking treatment, the scalp condition of the patient was much improved. At first, yellowish to reddish scaly pimples appear along the hairline and itching was severe. There were thick and black crusts on the scalp, red, greasy skin covered with flaky white or yellow scales. After that the crusts were fell off and the itching was disappeared during the treatment period. And then the hair loss was occurred. After a year of treatment, scalp condition and hair were back to normal. Conclusion : Herbal medicine (Hyeongbangpaedoksangamibang) with oriental medical treatments was effective in the treatment of seborrheic dermatitis of the scalp and it helped to improve regenerating the scalp condition.

• The Journal of Internal Korean Medicine
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• v.23 no.2
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• pp.268-273
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• 2002

Anticonvulsant hypersensitivity syndrome includes fever, skin eruptions, lymphadenopathy, hematologic abnormality and hepatitis, but its mechanism remains unknown. Anticonvulsants including phenytoin, carbamazepine can cause hypersensitivity reaction. We treated a patient who had severe itching sensation and insomnia: he had undergone an operation for cerebral hemorrhage and was administered anti-convulsant agents to prevent convulsions. We administered the anti-convulsant, Dangkwieumja(Dangguiyinzi). After the treatment, clinical symptoms caused by hypersensitivity were improved.

• The Korean Journal of Nuclear Medicine
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• v.14 no.2
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• pp.35-40
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• 1980

In order to compare the therapeutic effect as well as side effects between antithyroid therapy and radioiodine therapy in hyperthyroidism, the author evaluated 111 cases of hyperthyroidism which were composed of 57 patients with antithyroid treatment, 23 patients with combined treatment comprising of antithyroid and radioactive iodine ($^{131}I$) and 31 patients with treatment of $^{131}I$ alone. The $^{131}I$ treatment was limited to older age, above 20 years of age, and not employed in patients with pregnancy and lactation. The patients treated with antithyroid belonged to relatively younger age, and also milder in symptoms and thyroid function tests. The remission rate of antithyroid therapy group was 97.8% within 16 months. Among them the early remission rate occured within 4 months was found to be 21.7%. The combined therapy group, having prescribed more severe cases, showed the remission rate to be 75% within 16 months. The remission rate of $^{131}I$ therapy group revealed 90.9% within 16 months. Among them the early remission rate taking place within 4 months disclosed 16.7%. The side effects of antithyroid drug, propylthiouracil, were noted as follows: itching (2.7%) skin rashes (1.3%), and adverse enlargement of goiter (10.7%). The side effects $^{131}I$ therapy were transient hypothyroidism(3.9%) permanent hypothyroidism (7.8%) and itching (2.0%).

• Journal of Acupuncture Research
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• v.20 no.1
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• pp.244-253
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• 2003

Objective : Interferon-alpha and Rivabirin are much used at the same time to treat Chronical C viral hepatitis. But interferon caused lots of unexpected side effects, Acupuncture Treatment for them will be an alternative plan. Methods : We first posed questions to a 4 year-old man who ha skin flare, fatigue, itching, insomnia, pronounced a diagnosis based on overall of symptoms and signs and then treated Acupuncture, Moxibustion and Electroacupuncture. We acupunctured a BL17, BL18, BL20 and removed it at once. We electroacupunctured at GV20, Yin tang(Ex-HN3) form 20 minutes, acupunctured at Bi yi(鼻翼, Extra-point), S36, P6. Pizhengge(脾定格) was acupunctured for 10 minutes. Results : The symptoms of fatigue, insomnia, itching are reduced after acupuncture treatments and they made a person keep interferon treatment on. Conclusions : We confirmed that acupuncture treatments make a patient of chronic C viral hepatitis reduce and improve side effects of interferon treatment. We should keep on studying the various and efficient method of acupuncture treatment to improve living quality and treatment efficiency of patients.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.9 no.1
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• pp.114-128
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• 1996

"Chimumchang" seems to be a kind eczema. The cause and symptom of eczema is similar to that of chimumchang. so, I investigated the literatures of oriental medicin and recent medicine. The results are summarized as follows. 1. Chimumchang seems to be a kind of eczema. Allergic contact dermatitis, atopic dermatitis, seborrheic dermatits, neurodermatitis, nummular dermatitis, xerotic eczema and so on are similar to chimumchang on cause & symptom. 2. The cause of chimumchang are summer vital energy excess(夏脈太過), sehwa excess(歲火太過), herat meridian wind-heat(心經風熱), heart fire(心火), wind taken spleen dampnees(脾濕受風), and so on. The cause of eczema are contact of external agent, immunological problem, heridity, infection, abnormalities of sebaceous glands, neurologic dysfuction, and so on. 3. The symptoms of chimumchang have been described to the three pattern on literature of oriental medicine until now. 1) scratching slightly, It has exudation, and combination. 2) Vital energy on skin is irritable by psychological problem. At the acute stage the patient is complain of itching & pain, and gradually the exudation expands in whole body. 3) early peorid it's size is very small, and at first the patient is complain of itching, later complain of pain. The exudation change to ulcer and expands in the whole body. 4. In the investigation of prescription(Total: 34, Oral medicine: 4, Ointment: 30), the most frequently used oral medicine is sungmatang(4 times), and the most frequently used ointment are kohosan, korvunsan and kegwanhyuldobang.