• 한국한의학연구원논문집
• /
• 제16권3호
• /
• pp.107-113
• /
• 2010

Objective : Active treatment for a skin condition has produced a substantial change in the history of allergic contact or wound induced dermatitis. The frequency of opportunistic contacts and allergen-related dermatitis has increased, though new skin treatments have developed. Especially, there has been a interest in the korean herbal bathing. This study was performed to investigate the effects of the korean herbal bathing candidates on skin lesions in mice model. These candidates are Korea's representative herbs on skin lesions. Method : ICR mice were divided into five groups : naive, control, experimental group A and B and C. Control and experimental groups induced skin lesions by DNFB and TMA. Each experimental group was pasted with corresponding korean herbal bathing candidates on skin lesions. Result : Significant improvements in skin wound index, epidermal thickness associated with skin lesions were seen with the korean herbal bathing candidates. Conclusion : These results suggest that the korean herbal bathing candidates could be at least as effective as steroid, anti-histamine for the treatment of skin lesions.

• 한국응용과학기술학회지
• /
• 제26권2호
• /
• pp.103-109
• /
• 2009

Chemicals for cosmetics, including skin, the skin absorbs some of the research in the field of science or pharmacy recently, about the environment and the health of the heightened interest in skin absorption. Many other human attributes and absorption evaluation studies are underway in various areas. This study were used rats and carried out to find out the effects of commercial permanent wave products to skin which are composed with thioglycolic acid and bases. Results were as follows. Permanent wave penetrated to 3 hours later with steady state in skins and was not significant changeable after 20hr later. In case of neutralizer with thioglycolic acid lag time and permeability coefficient in healthy skin were 3.32hr and $0.101{\mu}g/cm^2/hr$, in old skin were 3.08hr and $0.117{\mu}g/cm^2/hr$, and in wounded skin were 3.02hr and $0.166{\mu}g/cm^2/hr$. In conclusion, lag time and permeability coefficient in old skin and wounded skin were faster than healthy skin. In vivo, We were studied to general time and method of permanent wave. We found out that fine wrinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.258-267
• /
• 2003

Recently inside nano liposome particles or nano-emulsions which contain tough-melting physiology activity materials or the coefficient of low organism utilization promote the coefficient of organism utilization, so this part has been studied a lot because they can absorb selectly cosmetics, specially physiology activity materials, into the skin. Also, in particle size, cells interstitial lipid interval are 30~50nm, so nano-emulsions that the size is similar to 30~50 nm are made to study for absorbing quickly into the skin. And transparent skin which contains oils in common skin lotion dosage form has become the center of public interest. The used nano-emulsions in this study were unsaturated lecithin/co-surfactant! ethanol/ oil / water. And polysorbate 20/ polysorbate 80/ Dicetyl phosphate/hydrogenated .caster oil/ isoceteth-20/SLS were used in co-surfactant. The used oils were cyclomethicone and caprylic/capric triglyceride. The manufacturing process was that microfluidizer was fixed in 1000bar and transit times were changed from 1 to 10 times. From transparency and particle size, the transparency sequence was SLS> polysorbate 20= polysorbate 80> isoceteth-20> dicetyl phosphate >hydrogenated caster oil and the particle size was small. Specially cyclomethicone nano-emulsions, when we made unsaturated lecithin /SLS /ethanol/water/cyclomethicone, cyclomethicone 5％ was good for transparency. And 20％ of this was used for making transparent skin toner in common skin dosage form.

• Journal of Microbiology and Biotechnology
• /
• 제31권5호
• /
• pp.637-644
• /
• 2021

Malassezia is the most abundant genus in the fungal microflora found on human skin, and it is associated with various skin diseases. Among the 18 different species of Malassezia that have been identified to date, M. restricta and M. globosa are the most predominant fungal species found on human skin. Several studies have suggested a possible link between Malassezia and skin disorders. However, our knowledge on the physiology and pathogenesis of Malassezia in human body is still limited. Malassezia is unable to synthesize fatty acids; hence, it uptakes external fatty acids as a nutrient source for survival, a characteristic compensated by the secretion of lipases and degradation of sebum to produce and uptake external fatty acids. Although it has been reported that the activity of secreted lipases may contribute to pathogenesis of Malassezia, majority of the data were indirect evidences; therefore, enzymes' role in the pathogenesis of Malassezia infections is still largely unknown. This review focuses on the recent advances on Malassezia in the context of an emerging interest for lipases and summarizes the existing knowledge on Malassezia, diseases associated with the fungus, and the role of the reported lipases in its physiology and pathogenesis.

• 한국의류학회지
• /
• 제39권4호
• /
• pp.505-516
• /
• 2015

This study investigated difference of product interest and its relation to consumers' innate innovativeness according to gender as well as compared the perceptive construct of products between male and female consumers. A survey involving male and female college students was conducted in the Daegu and Gyeongbuk areas in December 2013. Subsequently, 400 responses were analyzed using descriptive statistics, correlations, independent sample t-test, reliability analysis, ANCOVA, and multidimensional scaling. Among 45 products, male respondents showed a significantly high degree of interest over 12 categories such as watches, desktop computers, cars, sports products, and video games compared to females. The female sample showed a significantly high degree of interest for 29 product categories such as clothing, movies, skin care shops, cosmetics, eating-out, teeth whitening, coffee, cameras, and performances compared to males. Innovative male consumers were interested in traveling, movies, clothing, eating-out, running shoes, and wallets; however, female consumers' innovativeness was significantly related to previously determined items of interest. Two dimensions explaining the male consumers' products perception construct were 'hard versus soft' and 'usual versus special'. Instead, female consumers' were 'special versus usual' and 'expressive versus functional'.

• 대한화장품학회지
• /
• 제22권2호
• /
• pp.141-152
• /
• 1996

Many eastern females concern themselves about the condition and the color of their skin. The purpose of the present study is to classify the skin trouble and the change of the facial color due to hormonal cycle in female. We examined the actual cricumstances by questionnaires, and made patch tests of methyl nicotinate, representing rubefacient, to estimate the epidermal penetratin rate, and measured the facial color change during the menstrual cycle period to invest the correlation factors between skin trouble due to cosmetics and facial color change. Fifty-two percent of subjects had skin trouble relating to cosmetics. One second of subjects with skin trouble due to cosmetic complained the change of sysptom by menstrual cycle. The changes of systptom were related on premenstrual period. The skin trouble developed mainly on the first trimester of the pregnancy. In patch test of methyl nicotinate, most cases showed decreased threshold of the reaction on minstruation, and other cases showed increased reactivity of the skin of menstruation. In facial color measurements, it proves in the appearance of red spot, darkness, increasing the value and turning the hue to yellowish, Also it demonstrates that premenstruation hue turn red and value level decrease. During the period, facial color turns pale and hue progress to yellow. This fact coincides with the questionnaire. We have quqntified through questionnaire, which demonstrates it has good correlation with done to the subjects among the internal environment factors hormonal cycle influences the facial color change and the skin trouble due to cosmetics. Through this paper the development of an more fragmented make-up and skin care products is required to increase the interest to females, to make true the creation of beauty.

• 한국패션뷰티학회지
• /
• 제2권3호
• /
• pp.1-10
• /
• 2004

The purpose of this study is to find out the operant factors, or types of skin care, and, more importantly, to propose the intervention for more effective skin care and marketing strategies in this business. That is the main reason that the study employes Q methodology which measures human subjectivity objectively and scientifically. This study finally revealed three distinctive factors : Type I, The Passive Follower, Type II, The Active Needs, and Type III, The Independent Judgment. The first type includes people who show passive recognition. They want to be put in charge of experts in the skin care center and to buy cosmetics recommended by experts, and are deep interest in the reaction of other people. The second type contains people who desire things actively. To live delightfully and fashionably, they think of the necessity of skin and body care as an important thing, and feel that it is necessary to take care of the skin beauty actively and regularly for the aging resistance. The third type includes people who judge independently. In general, they recognize and desire the necessity of the skin care, but they think of the skin care as a part of the health care more widely rather than a special thing. These three types are not fixed, but continuously changed in the accordance with the condition and interaction with the circumstance, the results will be utilized as basic materials for the skin and health care through the application according to the characteristic of each type they belong.

• 한국산학기술학회논문지
• /
• 제21권12호
• /
• pp.672-678
• /
• 2020

최근 들어 초고속의 영상 촬영이 가능한 저가이며 성능이 우수한 카메라가 등장함에 따라서 물체의 미세한 움직임까지 정확하게 묘사한 초고속의 영상들이 보편화되고 있는 실정이다. 본 논문에서는 빠른 속도로 입력되는 초고속의 영상으로부터 예기치 않게 포함된 잡음을 제거한 다음, 잡음이 제거된 영상으로부터 피부 영역과 같이 개인 정보를 대표할 수 있는 관심 영역을 추출하는 방법을 제안한다. 본 논문에서는 먼저 입력받은 초고속의 영상으로부터 비정상적인 전기 신호로 인해 발생한 잡음을 양방향의 필터를 적용하여 제거한다. 그런 다음, 사전 학습을 통해 생성한 색상 분포 모델을 사용하여 영상 내에 포함된 개인 정보를 대표하는 관심 영역인 피부 영역을 정확하게 추출한다. 실험 결과에서는 본 연구에서 소개된 알고리즘이 여러 가지의 초고속 영상으로부터 잡음을 제거한 다음 관심 영역을 강인하게 추출한다는 것을 보여준다. 본 논문에서 제시된 접근 방법은 영상 전처리, 잡음 제거, 목표 영역의 추적 및 감시 등과 같은 컴퓨터 비전 및 패턴인식과 관련된 여러 가지의 응용 분야에서 유용하게 사용될 것으로 예상된다.

• 전기학회논문지
• /
• 제63권1호
• /
• pp.173-178
• /
• 2014

In this study, the new color image processing algorithms with an android-based mobile device are developed to detect the abnormal color densities in a skin image and interpret them as the vitiligo lesions. Our proposed method is firstly based on transforming RGB data into HSI domain and segmenting the imag into the vitiligo-skin candidates by applying Otsu's threshold algorithm. The structure elements for morphological image processing are suggested to delete the spurious regions in vitiligo regions and the image blob labeling algorithm is applied to compare RGB color densities of the abnormal skin region with them of a region of interest. Our suggested color image processing algorithms are implemented with an android-platform smartphone and thus a mobile device can be utilized to diagnose or monitor the patient's skin conditions under the environments of pervasive healthcare services.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.352-373
• /
• 2003

Rhamnose-rich (RROP-s) and fucose-rich (FROP-s) oligo-and polysaccharides were prepared and extensively characterised by physical and chemical procedures [1,2] and compared to L-fucose. Their biological properties were then studied on human skin fibroblast cell cultures, human skin explant cultures and on hairless rat skin, using a variety of cell-biological, biochemical and computerised morphometrical procedures. Among the most important properties we could establish, the following are of particular interest for the tretment and prevention of age-dependent modifications of human skin (loss of skin-tissue, cells and matrix, wrinkle formation and others) : stimulation of cell proliferation (by $^3$[H]-thymidine incorporation and the MTT test), scavenging of reactive oxygen species (ROS) using several different procedures, and protease (MMP-2 and MMP-9) down-regulation. A topical preparation, using RROP-s and FROP-s, and/or L-fucose, was shown to increase cell proliferation, dermal matrix synthesis, efficient scavenging of ROS-s and to increase also the thickness of dermal tissue when applied for 4 weeks on hairless rat skin, accompanied by the densification of collagen bundles as well as by an increase of elastin synthesis. Using fluorescent labeled FROPs, it could be shown that these oligosaccharides react with cell-membrane receptors and especially with the elastin-laminin-receptor and the fucose-mannose receptor, but they penetrate also in the cell nucleus, suggesting the possibility of a direct action on the regulation of gene expression. When applied to the human skin of a team of voluntary women encompassing all age-groups, the efficiency of FROP-containing preparation could be confirmed using indentometry and computerised evaluation of skin micro-relief, as well as evaluation of periorbital wrinkles. It appears therefore that these preparations correspond to all the requirements of active anti-aging principles.