• Title/Summary/Keyword: Skin Diagnosis

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Identification of Fungus from Dog and Diagnosis using PCR (개에서 분리한 진균의 동정과 PCR을 이용한 진단)

  • 장화석;문영찬;이상원;김휘율;김태종
    • Journal of Veterinary Clinics
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    • v.21 no.1
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    • pp.35-44
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    • 2004
  • This study was performed to examine the mycological features of canine skin. A total of 50 dogs with skin lesions were examined for dermatology from October, 2000 to April, 2001. The isolation rates of dermatophytes, yeast, filamentous fungi and superficial fungi were 36.4%, 13.5%, 35.3% and 13.6%. The dermatophytes isolated in dogs were Microsporum canins and Trichophyton mentagrophytes were 75% and 25%. The yeast and superficial fungi isolated in dogs were Candida albicans, Rhodntorula minnata, Candida ceferrii and Malassezia spp. were 16.7%. 16.7%, 16.7% and 50%. The filamentous fungi by Aspergillus funigatus, Aspergillus niger, Penicillum spp., Alternaria spp. were 12.5%, 12.5%, 50%, and 25%. In determine if polymerase chain reaction (PCR) could be applied for diagnosis of dermatophytes, yeast and filamentous fungi, control and clinical samples were tested. The size of specific PCR product in agarose gel was 340 bp for dermatophytes and 210 bp for yeast and filamentous fungi, respectively.

Development of Pulse Wave Analysis Model with Skin Effect (손목의 피부특성을 고려한 맥상파 해석모델 개발)

  • Shin, Sang-Hoon
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.15 no.2
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    • pp.159-168
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    • 2011
  • Objectives: The purpose of this study is to develop the pulse wave analysis model with the palpation pressure and the skin effect. Methods: The position of pulse diagnosis was modeled with elastic string system. The skin was modeled with the elastic string, the palpation pressure with tension in the string, and the blood vessel pressure with external force on the string. Using the wave equation in the physics, the simplified pulse model was transformed to the mathematical model. Results: To the verification of the model, the effects of the palpation pressure and the skin effect were tested. Conclusions: There was optimal palpation pressure, describing the exact vessel pressure pattern and maximizing the amplitude of the skin displacement. For the optimal condition, the increased palpation pressure was needed with the increased skin thickness. Therefore, the developed pulse wave analysis model showed the good results.

Cutaneous asthenia associated with Ehlers-Danlos syndrome in a Yorkshire terrier

  • Cho, Sung-Jin;Kim, Okjin
    • Korean Journal of Veterinary Research
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    • v.47 no.1
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    • pp.91-94
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    • 2007
  • tisue disease of dog and cat, resembling Ehlers-Danlos syndrome (EDS) in man. EDS is characterizedby loose, hyperextensible and, fragile skin, it is attributed to mutations in connective tisue gene. Thesemutations cause defects in type I or II collagen synthesis and as a result lack of strength or elasticityto skin, joint, ligament and vessels. EDS-affected animals often experience subcutaneous hematomas thathave long bleeding times. The 4-years old male Yorkshire terrier was evaluated because of subcutaneoushematoma after stifle surgery. Clinical examination revealed a thin and hyperextensible skin and jointlaxity. The degree of skin extensibility index was 23.4%, marked skin stretchy. Clinical diagnosis wasconfirmed by histophathological examination of a skin biopsy revealing reduced packing density ofcollagen fiber of skin.

When Are Circular Lesions Square? A National Clinical Education Skin Lesion Audit and Study

  • Miranda, Benjamin H.;Herman, Katie A.;Malahias, Marco;Juma, Ali
    • Archives of Plastic Surgery
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    • v.41 no.5
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    • pp.500-504
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    • 2014
  • Background Skin cancer is the most prevalent cancer by organ type and referral accuracy is vital for diagnosis and management. The British Association of Dermatologists (BAD) and literature highlight the importance of accurate skin lesion examination, diagnosis and educationally-relevant studies. Methods We undertook a review of the relevant literature, a national audit of skin lesion description standards and a study of speciality training influences on these descriptions. Questionnaires (n=200), with pictures of a circular and an oval lesion, were distributed to UK dermatology/plastic surgery consultants and speciality trainees (ST), general practitioners (GP), and medical students (MS). The following variables were analysed against a pre-defined 95% inclusion accuracy standard: site, shape, size, skin/colour, and presence of associated scars. Results There were 250 lesion descriptions provided by 125 consultants, STs, GPs, and MSs. Inclusion accuracy was greatest for consultants over STs (80% vs. 68%; P<0.001), GPs (57%) and MSs (46%) (P<0.0001), for STs over GPs (P<0.010) and MSs (P<0.0001) and for GPs over MSs (P<0.010), all falling below audit standard. Size description accuracy sub-analysis according to circular/oval dimensions was as follows: consultants (94%), GPs (80%), STs (73%), MSs (37%), with the most common error implying a quadrilateral shape (66%). Addressing BAD guidelines and published requirements for more empirical performance data to improve teaching methods, we performed a national audit and studied skin lesion descriptions. To improve diagnostic and referral accuracy for patients, healthcare professionals must strive towards accuracy (a circle is not a square). Conclusions We provide supportive evidence that increased speciality training improves this process and propose that greater focus is placed on such training early on during medical training, and maintained throughout clinical practice.

Differences Between Facial Skin Temperature of the Paralyzed Side and Those of the Normal Side in Bell's Palsy Patients (Bell's Palsy 환자의 건측-환측 안면부 피부온도차이에 관한 연구)

  • Nam, Dong-Hyun;Koh, Hyung-Kyun;Park, Young-Bae
    • The Journal of Korean Medicine
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    • v.28 no.1 s.69
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    • pp.126-136
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    • 2007
  • Objectives : Bell's palsy in an acute peripheral facial nerve paralysis that usually affects only one side of the face. The seventh cranial nerve carries predominantly motor fibers, but also supplies some autonomic innervation, sensation to park of the ear, and taste to the anterior two thirds of the tongue. The aim of this study is to provide evidence of differences between facial skin temperature of the paralyzed side and normal side in Bell's palsy patients. Methods : the author studied 68 patients with Bell's palsy whose facial nerve function had been documented by the House-Brackmann grading system. We measured skin temperature of the forehead, zygoma, lower lip, temple and lower jaw area of the paralyzed side and those of the normal side. Results : there were significant facial skin temperature differences between the forehead area of paralyzed side and that of normal side of GrII(P<0.05) and III(P<0.05). The result also showed that the facial skin temperature difference according to the aflection period vanished when air temperature was calibrated (F=1.700, P=0.178). Conclusions : Thermography is a useful diagnostic tool in Bell's palsy if the air temperature is low enough to cool the facial skin temperature and the forehead area is evaluated as the sampling zone.

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Imperceptible On-Skin Sensor Devices for Musculoskeletal Monitoring and Rehabilitation (상시 근골격 모니터링과 재활을 위한 온스킨 센서 디바이스 기술)

  • Park, C.W.;Koo, J.B.;Jin, H.;Kim, Y.;Lim, C.;Hong, C.H.;Kim, H.J.
    • Electronics and Telecommunications Trends
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    • v.37 no.2
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    • pp.30-41
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    • 2022
  • As the society is superaging, the number of patients with movement disabilities due to musculoskeletal or nervous system illness is rapidly increasing. To improve public health and reduce medical expenses, it is essential to develop rehabilitation systems that allow patients to resume their daily-life activities. However, the existing musculoskeletal illness diagnosis and rehabilitation method is limited in terms of precision and efficiency because it is based on an empirical diagnosis and prescription without regard for individual characteristics. To overcome these limits, it is critical to design a novel concept of routine rehabilitation therapy device that is capable of inducing musculoskeletal balance by the precise analysis of musculoskeletal usage patterns via the motion and the muscle activity tracking of linked muscles. This study introduces the trend of on-skin sensor device technology for routine musculoskeletal monitoring and therapy. For on-skin rehabilitation systems, skin-adhesive and stretchable motion/posture, electromyography, pressure sensors, small-size and low-power wireless sensor interfaces, and user-friendly rehabilitation contents based on new algorithms are combined.

A Study on the Direction of Evaluation Indicators for Personalized Beauty Self-care

  • Lee, Yoo-jeong;Choi, Ji-woo;Shin, Sae-young
    • Journal of Fashion Business
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    • v.24 no.6
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    • pp.120-134
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    • 2020
  • Recently, the beauty industry has implemented personalized services based on skin big data. To increase competitiveness in the beauty industry, systematic data measurement and evaluation indicators are necessary to select data and obtain necessary knowledge. In response, this study sought to stably enhance the accuracy of skin diagnosis based on satisfaction and reliability. To this end, the research was conducted through focus group interviews (FGI), a case study of brands, and analysis of prior research results. In particular, as a result of analyzing keywords that classify skin types by brand, common survey items for skin types were oiliness and using moisturizer, cosmetic use and vascular of skin, external stimulus and blemish & freckles, facial wrinkle, outside activities, self-consciousness, and smoke. In additioin to the common questions of the preceding study and the brand survey items, the questions concerning complex skin types, seasonal change, facial color, wrinkles and elasticity were added, and the questions were presented in a total of 40 items. In particular, it suggested that skin measurement could be conducted by focusing on elasticity and pigmentation items by reflecting the results of prior research and the opinions of FGI, and based on this, a customized service with high satisfaction and high accuracy of beauty care based on this could be proposed. We hope that this study will facilitate active self-care by providing more satisfying skin stones and personalized cosmetics proposals, thus laying the foundation for the further development of the cosmetics industry.

A Comparative Study according to Diagnostic Time on Meningitis (무균성 뇌막염에서 증상발현부터 진단까지 걸린 시간에 따른 시기별 유병기간의 검토)

  • Kim, Tag Soo;Hur, Ji Yeon;Park, Young Hee;Jung, Min Goo;Kim, Sung Won
    • Pediatric Infection and Vaccine
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    • v.3 no.2
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    • pp.168-174
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    • 1996
  • Purpose : Aseptic meningitis is relatively frequent in children and caused mostly by enterovirus. The aim of the present study was to determine the effect of early diagnosis (spinal tapping) on symptom duration of childhood aseptic meningitis. Methods : One hundred fifty-three children who were hospitalized due to aseptic menigitis in the Department of Pediatrics St. Benedict Hospital from July 1996 through October 1996 were included in this study. Patients were divided to two groups according to the duration from first symptom onset to diagnosis. Early diagnosis group is diagnosed within 3 days from first symptom onset. Later diagnosis group is diagnosed after 4 days from first symptom onset. Results : 1) The average age of these patients was 4.3 years old in early diagnosis group and 4.1 years old in later diagnosis group. The sex ratio(male: female) was 2.04:1 in early diagnosis group and 2.5:1 in later diagnosis group. 2) The mean duration of diagnosis of this study was 2.04 day in early diagnosis group and 5.12 day in later diagnosis group. 3) The percentage of symptom and sign of the early diagnosis group were fever(100%), headache(88.4%), vomiting(86.9%), abdominal pain(39%), neck stiffness(36.2%), skin rash(18.8%), diarrhea(16.9%) and that of later diagosis group were fever(100%), headache(83.3), vomiting(80.9%), abdominal pain(47.6%), neck stiffness(41.6%), skin rash(29.7%), diarrhea(16.6%). 4) Initial CSF findings revealed leukocyte $146.8{\pm}386.3/mm^3$ with PMNL 38%, protein 32.47mg/dl, sugar 66.23mg/dl in early diagnosis group and leukocyte $458.1{\pm}663.2/mm^3$, protein 31.22mg/dl, sugar 64.21 mg/dl in later diagnosis group. 5) There was no statistically significant differance in the peripheral blood findings between early diagnosis group and later diagnosis group. 6) The duration of disappearance of symptom after spinal tap were 2.3 days in early diagnosis group and 2.24 days in later diagnosis group. Total symptom duration was 4.34 days in early diagnosis group and 7.36 days in later diagnosis group. Conclusions : Our results demonstrate that early diagnosis(early spinal tap) shortened duration of clinical symptoms.

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Clinical Experience of Pyoderma Gangrenosum with Extensive Soft Tissue Necrosis (광범위 연조직 괴사를 동반한 괴저농피증의 치험례)

  • Lim, Sung Yoon;Park, Dong Ha;Pae, Nam Suk;Park, Myong Chul
    • Archives of Plastic Surgery
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    • v.35 no.5
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    • pp.615-618
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    • 2008
  • Purpose: Pyoderma gangrenosum is a rare cutaneous ulcerative disease. First described in 1930, the condition is characterized by progressive ulceration with deeply undermined purple-red edge. The lower extremities are most commonly affected but other parts of the skin and mucous membranes may also be involved. Although medical treatments with topical wound therapy are commonly used, surgical intervention is still controversial. In this paper, we report an atypical case of pyoderma gangrenosum which was characterized by extensive soft tissue breakdown. Methods: A 27-year-old male patient was referred to our institution with a $7{\times}8cm$ sized deeply undermined ulceration with pus-like discharge and fever. Incision and drainage was performed at another clinic 3 days prior to admission to our institution. After a thorough physical examination and the MRI review, a diagnosis of necrotizing faciitis was made. Accordingly, fasciotomy and debridement was performed. However, the wound enlarged progressively and the patient remained highly febrile for 9 days after the treatment. Septic screening did not reveal any occult infection. After a secondary review of the case, the initial diagnosis of necrotizing fasciitis was rejected and changed to pyoderma gangrenosum. With the use of dexamethasone intravenously, the wound improved dramatically and the fever was eliminated. Steroid mediation was tapered with duration of 1 month. The wound was stabilized and subsequently covered with split-thickness skin graft. Results: Split-thickness skin grafting with 1 : 1.5 mesh was successfully taken. Conclusion: Initial clinical features of pyoderma gangrenosum are very similar to that of necrotizing fasciitis. High fever and progressive ulceration with severe pain could invite earlier surgical approach. The advancing wound margins (the well defined violaceous, undermined border and necrotic ulcer base) and lack of isolation of pathogenic organism was used to make the correct diagnosis of pyoderma gangrenosum. We achieved a good result with proper medication and split-thickness skin graft.

A Diagnosis Method of Basal Cell Carcinoma by Raman Spectra of Skin Tissue using NMF Algorithm (피부 조직의 라만 스펙트럼에서 NMF 알고리즘을 통한 기저 세포암 진단 방법)

  • Park, Aaron;Baek, Sung-June
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.8
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    • pp.196-202
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    • 2013
  • Basal cell carcinoma (BCC) is the most common skin cancer and its incidence is increasing rapidly. In this paper, we propose a diagnosis method of basal cell carcinoma by Raman spectra of skin tissue using the NMF(non-negative matrix factorization) algorithm. After preprocessing steps, measured Raman spectra is used classification experiments. The weight and the basis can be obtained in a simple matrix operation and a column vector of the matrix decompsed by the NMF. Linear combination of bases and weights, it is possible to approximate the average of Raman spectra. The classification method is to select the class which to minimize the root mean square of the difference of the linear combination and the objective spectrum. According to the experimental results, the proposed method shows the promising results to diagnosis BCC. In addition, it confirmed that the proposed method compared with the previous research result could be effectively applied in the analysis of the Raman spectra.