• Maxillofacial Plastic and Reconstructive Surgery
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• v.18 no.4
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• pp.718-725
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• 1996

Histiocytosis X is the abnormal proliferation of histiocytes and usually a massive aggregation of eosinophilic leukocytes. The clinical features and prognosises of subclasses of histiocytosis X depend on the severity and extent of the organ involvement. The subclasses include Letterer-Siwe disease(Acute disseminated histiocytosis X), eosinophilic granuloma, Hand-Schuller-Christian disease. Letterer-Siwe disease(acute, subacute form) refers to the form of disease that is most often fatal because of the widespread skeletal, extraskeletal lesion ; this usually affects infants and children less than 3 years of age. Eosinophilic granuloma(histiocytosis X, localized) refers to a chronic form of disease with skeletal lesion ; It usually affects children and young adult. Hand-Schuller-Christian disease(chronic form) refers to a chronic form of disease with skeletal, extraskeletal lesions. It usually affects children over the age of 3 years. In our hospital, 8 year old female patient visited complaining of hard swelling of mandibule body, left side and 6 year old female patient visited complaining of painful swelling of mandibular angle, right side. We diagnosed eosinophilic granuloma and curetted the lesiones and refered to Dept. pediatrics for chemotherapy. We present 2 cases to you with literatures.

• The korean journal of orthodontics
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• v.22 no.3 s.38
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• pp.627-646
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• 1992

The purpose of this study was to investigate the relationship among the activity of the craniofacial muscle and craniofacial form and occlusal state. In this study, subjects were consisted of 23 male adults with skeletal Class III malocclusion and 30 male adults with normal occlusion. The measurements in oral exam, lateral ceghalogram, and E.M.G. recordings of anterior temporal, masseter, and upper lip muscles at rest position, clenching in centric occlusion, chewing of gum, swallowing of juice, were analyzed with SPSS system. The results were as follows: 1. At rest position upper lip muscle activity of skeletal Class III group was significantly higher than that of normal group. 2. Both clenching and chewing masseter and temporal muscle activity of normal group were significantly higher than that of skeletal Class III group. 3. During swallowing of juice, upper lip muscle activity of skeletal Class III group were significantly higher than that of normal group. 4. The activities of masseter and anterior temporal muscle during clenching and chewing were significantly correlated with hypodivergent facial form and number of occluded teeth. 5. The activity of upper lip during swallowing had positive correlation with mandibular prognathism.

• Biomedical Science Letters
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• v.10 no.1
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• pp.23-29
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• 2004

Nebulin is a (Mr 600∼900 kDa) large actin-binding protein specific to skeletal muscle and thought to act as a molecular template that regulates the length of thin filaments. Cardiac muscles of higher vertebrates have been shown earlier to lack nebulin. Recently, full-length nebulin mRNA transcripts have been detected in heart muscle, but at lower levels than in skeletal muscle. Nebulin expression also was detected in the kidney, eye, and otic canal, suggesting that nebulin isoforms may also be expressed in these organs. We have searched for nebulin isoforms in brain of human using PCR and Northern blot. Here, we provide evidence that nebulin mRNA transcripts are expressed in brain. Seven nebulin isoforms (B, C, D, E, F, G and H form) are obtained in human skeletal muscle and four isoforms (B, C, G and H form) in human brain cDNA library. We cloned the 1.3 kb of nebulin fragment from human adult brain library by PCR. The identity of the PCR product was confirmed by sequence analysis. The partial brain nebulin sequence was 99% identical to the skeletal muscle cDNA as determined by Blast alignment. It contains two simple-repeats HR1, HR2 and linker-repeats exon l35∼143 except exon 140. It was different from skeletal muscle B form, which contain HR1 and HR8. These data suggest that nebulin isoform diversity occurs even more extensively than previously known, likely contributing to the distinct thin filament architecture of different striated muscles.

• The Korean Journal of Zoology
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• v.34 no.1
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• pp.31-43
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• 1991

In the present study, the localization of myosin and the pathway of myofibrilogenesis of skeletal muscle cells in culture were investigated by immunocytochemical methods including immunoelectron microscopy and hybridoma formation. There were manly free ribosomes in the cytosol of the myoblast. At 48 hr of the culture, the myofilaments started to form and at 72 hr began to assemble to form myoabrils. At this time the Z band appeared, but the sarcomeres did not link together. Aker 96 hr of culture, adjacent sarcomeres linked together and shotved the typical striation of the skeletal muscle fiber. Myosin was synthesized in free ribosomes at 24 hr of culture and localized at many myofilaments at 48 hr and assembled mvoabrils at 72 hr and at 120 hr of the culture, myosin was localized at thick filaments of the A band.

• Animal cells and systems
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• v.11 no.1
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• pp.55-60
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• 2007

Four new species, Semitaspongia jejuensis, Scalarispongia regularis, S. nigra and Dysidea violata are described from Jejudo, Korea. They were collected from 15 m depth by SCUBA diving and from intertidal area by hand. Semitaspongia jejuensis n. sp. is easily distinguished from other Semitaspongia species in growth form, conules, colour, skeletal structure, diameter of fibre and habitat. Scalarispongia regularis n. sp. is very close to S. scalaris (Schmidt, 1862) in skeletal structure, but S. scalaris has longer conules, larger meshes, longer distance between primary fibres, and highly developed subdermal canal system. Scalarispongia nigra n. sp. is very close to S. regularis in skeletal structure but can be easily distinguished by its black colour of external surface and growth form. Dysidea violata n. sp. is similar with D. ethria (Laubenfels, 1936) in sponge appearance, but D. etheria is clearly defined by its blue colour and thickness of fibre.

• The Journal of the Korean dental association
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• v.57 no.6
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• pp.344-351
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• 2019

Skeletal Class III malocclusion is a relatively common form of malocclusion in Korea. In borderline cases where only mild skeletal discrepancy exists and if worsening of the facial profile is expected as a result of premolar extraction, mandibular full arch distalization with miniscrews is the treatment of choice. The purpose of this study was to investigate the pattern of tooth movement and evaluate the stability of mandibular full arch distalization and to identify correlation between stability and factors such as initial skeletal pattern, dental changes during treatment and alveolar bone in symphysis region using lateral cephalograms.

• Earthquakes and Structures
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• v.10 no.1
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• pp.25-51
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• 2016

In this study, graph product rules are applied to the dynamic analysis of regular skeletal structures. Graph product rules have recently been utilized in structural mechanics as a powerful tool for eigensolution of symmetric and regular skeletal structures. A structure is called regular if its model is a graph product. In the first part of this paper, the formulation of time history dynamic analysis of regular structures under seismic excitation is derived using graph product rules. This formulation can generally be utilized for efficient linear elastic dynamic analysis using vibration modes. The second part comprises of random vibration analysis of regular skeletal structures via canonical forms and closed-form eigensolution of matrices containing special patterns for symmetric structures. In this part, the formulations are developed for dynamic analysis of structures subjected to random seismic excitation in frequency domain. In all the proposed methods, eigensolution of the problems is achieved with less computational effort due to incorporating graph product rules and canonical forms for symmetric and cyclically symmetric structures.

• Journal of Biomedical Engineering Research
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• v.38 no.6
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• pp.308-312
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• 2017

Skeletal muscle function plays a very important role in quality of life. However, skeletal muscle causes functional decline under aging or some diseases. Exercise and muscle training are good solutions to delay sarcopenia, but there are limitations to those who are uncomfortable in exercise. For this reason, alternative interventions for muscle sarcopenia are required, and many studies proved the increase of skeletal muscle mass by electrical stimulation. In conventional studies, however, mouse skeletal muscle cells have been mostly used in experiments to identify electrical stimulation conditions while human derived cells have not been frequently utilized in these studies. Stimulation used for rehabilitation has been uniformly treated without the consideration of aging. In addition, many studies have been used with conventional petri dish usually requiring many numbers of cells, which is not appropriate for rare. Moreover, they are not usually condition uniformity of electrical field. In this study, we have developed an electrical stimulation device which consumes a small amount of cells and can form a uniform electrical field. With the system, we analyzed the skeletal muscle differentiation and Myotube thickness depending on the electrical stimulation condition.

• Journal of the korean academy of Pediatric Dentistry
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• v.26 no.3
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• pp.473-478
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• 1999

Osteopetrosis is an uncommon hereditary bone condition characterized by a generalized symmetric increase in skeletal density and abnormalities of bone resorption remodeling. In 1904, the first case of generalized sclerosis of the skeleton was reported by $Albers-Sch\ddot{o}nberg$. Osteopetrosis is generally divided into two main type. The infantile(malignant, congenita) type is the most severe form of the disease; It is characterized by skeletal and hematologic abnormalities. The adult(benign, tarda) type which is usually diagnosed in the third or fourth decade of life is limited predominantly to skeletal anomalies and it carries a more favorable prognosis. The recently recognized intermediate form with its mild and variable clinical recessive trait. There is no reported gender or racial predilection. The characteristic feature of osteopetrosis which is an abscence of physiologic bone resorption results in accumulation of bone mass and mainfests skeletal disturbance. Dental finding of osteopetrosis includes delayed eruption, congenitally absent teeth, unerupted and malformed teeth, and enamel hypoplasia. Our report involves a patient with a chief complaint of tooth mobility and delayed eruption. After clinical and radiologic examination, this patient was referred to dept. of pediatrics under the suspicion of osteopetrosis and it was confirmed.

• Journal of the Korea Safety Management & Science
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• v.12 no.1
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• pp.59-62
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• 2010

At the present time, Musculo-Skeletal Disorders breaks out and it is increased in a high speed. It is a serious problem for the labors and managements. People becoming greatly interested in it. It is caused by the labor intensity which is according to the work form, hours of labor, and the labors and the labor unions have a correct understanding in it, and the labor powers becoming older, and the change of divisional social environment which is latent. Before working do the simple preparation gymnastics or operate insensitive exercise remedy without scientific verification only in the present circumstances. Although operate the Work-related Musculo-Skeletal Disorders exercise remedy, it can not get a sufficient effectiveness. So the study develop one type of exercise remedy which are divided the upper limbs exercise remedy, the trunk exercise remedy, the lower limbs exercise remedy. It can be done without using any exercise equipments and regardless places. We should also enable the exercise remedy to be easily applied to workers who are in different circumstances. To use EMG to measure the burden of exercise remedy. By doing so, employees can easily do exercises and it will help to prevent and even can treat MSD. It is just the objective of the research.