• Molecules and Cells
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• v.28 no.6
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• pp.565-573
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• 2009

The pig could be a useful model to characterize molecular aspects determining several delicate phenotypes because they have been bred for those characteristics. The Korean native pig (KNP) is a regional breed in Korea that was characterized by relatively high intramuscular fat content and reddish meat color compared to other western breeds such as Yorkshire (YS). YS grew faster and contained more lean muscle than KNP. We compared the KNP to Yorksire to find molecular clues determining muscle characteristics. The comparison of skeletal gene expression profiles between these two breeds showed molecular differences in muscle. We found 82 differentially expressed genes (DEGs) defined by fold change (more than 1.5 fold difference) and statistical significance (within 5% of false discovery rate). Functional analyses of these DEGs indicated up-regulation of most genes involved in cell cycle arrest, down-regulation of most genes involved in cellular differentiation and its inhibition, down-regulation of most genes encoding component of muscular-structural system, and up-regulation of most genes involved in diverse metabolism in KNP. Especially, DEGs in above-mentioned categories included a large number of genes encoding proteins directly or indirectly involved in p53 pathway. Our results indicated a possible role of p53 to determine muscle characteristics between these two breeds.

• The korean journal of orthodontics
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• v.28 no.2 s.67
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• pp.189-201
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• 1998

The purpose of this study was to evaluate the characteristics of craniofacial skeleton on orthognathic surgical cases with skeletal Class III malocclusion. For this study, 74 students at the dental college of Chosun University volunteered as a normal occlusion group. They had well-balanced faces and good occlusions with acceptable Class I molar relationship. They had not received orthodontic treatment and had no signs or symptoms of temporomandibular joint dysfunction. 45 malocclusion patients enrolled for orthognathic surgical treatment with skeletal Class III malocclusion at the Department of Orthodontics, College of Dentistry, Chosun University. On the basis of this study. the results of this study were as follows: 1. Skeletal Class III malocclusion was largely due to the overgrowth of mandible in man and the undergrowth of maxilla in woman. 2. The mandible was antero-inferiorly overgrown by large MP-HP angle and large genial angle in orthognathic surgical cases with skeletal Class III malocclusion. And also, upper incisors were severely labioversioned, but on the other hand lower incisors were linguoversioned. 3. In female, lower-third facial height was characteristically shortened in comparison with middle-third facial height and also, lower facial throat angle was small in male.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.8
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• pp.3552-3560
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• 2012

This study was conducted to find out the complaint rate of musculo-skeletal disorder and its related factors from male manufacturing workers at a nonferrous manufacturing industry. As for the research subjects, 302 workers selected from a nonferrous manufacturer located in Daejeon City, and as for the collection of data, a standardized anonymous questionnaire survey were conducted from May 1, 2011 to June 30, 2011. As a results, the complaint rate of musculo-skeletal disorders by each body part, the symptom of shoulders was 42.7%, the highest rate, followed by the waist, 36.8%, the neck and the hand/wrist/finger, 30.5% respectively, the leg and foot, 30.1% and arm/elbow, 20.9%. The complaint rate of musculo-skeletal disorder for the sociodemographic characteristics was significantly high as survey participants' age and BMI were low and in the group having low subjective health condition. The complaint rate of musculo-skeletal disorder for the health-related behavior characteristics was significantly high in the group having been absent from work due for diseases, in the group having received outpatient services, in the group having been hospitalized for treatment, in the group not having a regular exercise and in the group having insufficient sleeping hours. Finally, the complaint rate of musculo-skeletal disorder for the job-related characteristics was significantly high in the group suffering from the physical burden of their work, in the group working while bending at the waist and in the group carrying out repetitive tasks.

• Journal of the korean academy of Pediatric Dentistry
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• v.23 no.3
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• pp.624-630
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• 1996

Anterior openbite is defined as the lack of contacts between the functional occluding teeth on vertical line at centric occlusion and classified into functional and skeletal anterior openbite based on its causes and characteristics. Anterior openbite causes masticatory, speech, and esthetic problems in the growing children and difficulties in diagnosis, treatment, and the prediction of its prognosis. We are reporting on the treatment of anterior openbite in the growing children and the results follow as : 1. In the growing children with anterior openbite, the overbite could be increased by the treatment according to its causes and characteristics. 2. The prognosis is not determined by the presence or severity of oral habit but the skeletal tendency of the patient.

• The korean journal of orthodontics
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• v.31 no.4 s.87
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• pp.439-445
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• 2001

The Purpose of this study was to compare the dento-skeletal characteristics between functional and skeletal anterior cross-bite patients. Twenty-eight functional anterior cross-bite patients and thirty-one skeletal anterior cross-bite patients were selected as a test and a control group. Mean ages of the test and the control group were $9.6{\pm}1.8$ and $9.9{\pm}1.9$, respectively. Lateral cephalograms were taken. Forty-nine cephalometric variables were measured and statistical analysis was performed to find the morphological differences between the groups. Statistically significant differences were found in the cephalometric variables of cranial deflection, maxillary depth, ANB, convexity, NPo-AB, APDI, Mx 1-SN, Mx 1-NA angle, Mx 1-NA, Md 1-NB angle and Md 1-NB. The test group showed more Class III growth potential, more protruded maxilla, lesser maxillo-mandibular difference, more uprighted and retruded maxillary central incisor, more labially tipped and protruded mandibular central incisor.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6681-6684
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• 2015

Background: Metastatic cancer with invasion of skin, soft tissue and skeletal muscle is not common. Examples presenting as soft tissue masses could sometimes lead to misdiagnosis with delayed or inappropriate management. The purpose of current study was to investigate clinical characteristics in the involvement of metastatic cancer. Materials and Methods: A total of 1,097 patients complaining of skin or soft tissue masses and/or lesions were retrospectively reviewed from January 2012 to June 2013. Tumors involving skin, soft tissue and skeletal muscle of head and neck, chest wall, abdominal wall, pelvic region, back, upper and lower extremities were included in the study. Results: Fifty-seven (5.2%) patients were recognized as having malignancies on histopathological examination. The most common involvement of malignancy was basal cell carcinoma, followed by cutaneous squamous cell carcinoma, sarcoma and melanoma. The most common anatomical location in skin and soft tissue malignancies was head and neck (52.6% of the malignancies). Four (0.36%) of the malignant group were identified as metastatic cancer with the primary cancer source from lung, liver and tonsil and the most common site was upper extremities. One of them unexpectedly expired during the operation of metastatic tumor excision at the scalp. Conclusions: Discrimination between benign and malignant soft tissue tumors is crucial. Performance of imaging study could assist in the differential diagnosis and the pre-operative risk evaluation of metastatic tumors involving skin, soft tissue and skeletal muscle.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.3
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• pp.204-210
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• 2007

This study was intended to compare the cranial base morphology between the mandibular prognathism and maxillary retrognathism in skeletal class III patients. The subject of the present study was composed of 88 patients divided into two groups; Group 1 (Skeletal Class III with mandibular prognathism. SNA within normal range, SNB over normal range, n=54) and Group 2(Skeletal Class III with maxillary retrognathism. SNA below normal range, SNB within normal range, n=34). Lateral cephalogram were taken immediate before surgery and 18 landmarks were used to analyze the characteristics of cranial base and maxillomandibular skeleton. The result revealed that cranial base angle is significantly smaller in Group 1 than Group 2, which implies the influence of the cranial base angulation on the mandibular position. However the posterior cranial base length did not influence the mandibular horizontal position and anterior cranial base length did not influence the maxillary horizontal position. As the anterior cranial base length was closely related with ramal height, it is recommendable to investigate the regulatory mechanism of chondrogenesis of cranial base and condyle cartilage in the future research.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.4
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• pp.514-514
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• 2022

• Journal of the Korean Society of Physical Medicine
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• v.18 no.3
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• pp.21-30
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• 2023

PURPOSE: The present study evaluated the occurrence, somatometric, biochemical, and behavioral characteristics of young Korean sarcopenic males aged between 30 to 39 years. METHODS: The study involved a total of 1,546 participants. These individuals were divided into two distinct groups based on their skeletal muscle mass index. Of these, 49 participants were categorized into the sarcopenia group, while the remaining 1,497 individuals were placed in the normal group. The researchers analyzed the occurrence of sarcopenia, somatometric, biochemical, and behavioral characteristics such as height, weight, body mass index (BMI), waist circumference (WC), skeletal muscle mass index, fasting glucose (FG), triglyceride and total cholesterol (TC) levels, systolic (SBP) and diastolic blood pressure (DBP), and the drinking and smoking status. A complex sampling data analysis was performed. RESULTS: The weighted occurrence of sarcopenia was found to be 3.24%, (95% confidence interval (CI) of 2.39% to 4.36%). The somatometric contributing factors were height, BMI, and WC (p < .05). Triglyceride and TC levels exhibited statistically significant differences in the biochemical variables (p < .05). The behavioral characteristics, including the drinking and smoking status, had no statistical significance (p > .05). CONCLUSION: This study identified specific occurrences of sarcopenia and contributing factors in young Korean men.

• The korean journal of orthodontics
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• v.34 no.1 s.102
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• pp.93-107
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• 2004

Enlow's counterpart analysis explains the complex with anatomic and developmental characteristics where craniofacial aspect of Individuals has been developed. Counterpart analysis does not compare individual measurement with the normal value from the average of majority but analyzes by comparison of values that each individual has. In this study we examined surgical changes in skeletal Class III malocclusion patients(male 40, female 40) and compared them with normal occlusion patients using counterpart analysis. The results indicated that : 1. Skeletal anterior-posterior discrepancy was relieved by shortening of the ramus width(B3). 2. The ramus alignment(R3, R4) was displaced posteriorly and the occlusal plane angle(R5) was rotated clockwise. 3. Skeletal Class III pattern was relieved in the post-operative group, but differences in the level of the cranium(R1, R2) was remaining compared to the normal occlusion patients. 4. In the comparison of surgery methods, the two-jaw surgery group presented changes In the maxillary length(A4), ramus alignment(R3, R4) and occlusal plane angle(R5) compared to the one-jaw surgery group, but the differences were not significant. In the past study about Korean skeletal Class m patients, the skeletal characteristics are upward backward rotation of the cranial base, posterior displacement of the maxilla, forward inclination of the ramus and lengthening of the mandibular body, but in this study, skeletal Class m pattern was relieved by shortening of the ramus width and maxillary advancement by orthognathic surgery, because orthognathic surgery is usually performed on limited areas in the maxilla and the mandible.