• 제목/요약/키워드: Skeletal

검색결과 3,092건 처리시간 0.026초

Elevated SR $Ca^{2+}$ Channel Activity in Diabetic Skeletal Muscles

  • Kim, Won-Tae;Kim, Hae-Won;Kim, Young-Kee
    • 한국생물물리학회:학술대회논문집
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    • 한국생물물리학회 1997년도 학술발표회
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    • pp.30-30
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    • 1997
  • Dysfunctions of skeletal muscles have been frequently reported in chronic diabetic mellitus (DM). In order to investigate the molecular mechanisms of abnormal function, the junctional sarcoplasmic reticulum (HSR) vesicles of skeletal muscles were prepared from the control and the streptozotocin-induced diabetic rats.(omitted)

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근육에 대한 역학적 스트레스의 영향 (Review of Effect of the Mechanical Stress on Muscle)

  • 강종호;김진상
    • PNF and Movement
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    • 제6권2호
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    • pp.51-57
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    • 2008
  • Purpose : Mechanical stress activates signaling cascades and leading to a specific response of a network of signaling pathways. The purpose of this study is to review the effect of mechanical stress-induced adaptation in skeletal muscle involves a biological mechanisms. Methods : This is literature study with Pubmed, Medline and books. Results : Skeletal muscle tissue demonstrates a malleability and may adjust its metabilic response, vascularization and neuromuscular characteristic makeup in response to alteration in functional demands. The adaptation in skeletal muscle involoves a multitude of signalling mechanisms related with insuline-like growth factor, vascular endothelial growth factor, neurotrophins. Conclusions : The identification of the basic relationships underlying the malleability of skeletal muscle tissue is likely to be of relevance for our understanding with PNF technique.

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골격근의 노화에 대한 고찰 (A Review of Journals on the Aging Skeletal Muscle)

  • 권오봉;송윤경;임형호
    • 대한추나의학회지
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    • 제4권1호
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    • pp.55-65
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    • 2003
  • The purpose of this article was to contribute to the knowledge of physiological and pathological changes of aging skeletal muscles, and of therapic method. By aging there were changes of distribution of muscle fibers, the loss of muscle mass, the loss of the number of muscle fibers, the loss of glycolysis capacity, the decrease of the oxidative enzymes and muscle vascularization in the skeletal muscles. And as a pathological change, the exhaustive maximal exercise increased oxidative stress that led to oxidative damage which were shown to be implicated in promoting aging. The property of intensity and duration exercise is important not only in keeping human health and physical fitness from oxidative stress, but also for the maintenance of well-being and quality of life.

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골격성 III급 부정교합 환자 자매의 치험례 (Two treatment approach to skeletal class III : A case report on sisters)

  • 이유현
    • 대한치과교정학회지
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    • 제29권3호
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    • pp.327-337
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    • 1999
  • 골격성 III급 부정교합으로 진단된 자매들로서 이상적인 치료 계획은 둘 다 악교정 수술을 동반한 교정 치료였으나 언니의 경우만 술전 교정 후 양측성 하악지 시상 분할 골절단술로 치료하고 동생의 경우는 상악 제2소구치와 하악 제1소구치 발치를 통한 절충 치료를 시행하였다. 이에 본 증례 보고에서는 악교정 수술을 한 경우와 절충 치료를 한 경우를 비교하여 고찰해 보았다.

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Interrelationship of Runx2 and estrogen pathway in skeletal tissues

  • Jeong, Jae-Hwan;Choi, Je-Yong
    • BMB Reports
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    • 제44권10호
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    • pp.613-618
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    • 2011
  • Two key molecules in skeletal tissues are bone formation master transcription factor Runx2 and the steroid hormone estrogen. It is well known that these two molecules play pivotal roles in bone homeostasis; however, the functional interaction between Runx2 and estrogen synthesis in skeletal tissues is largely unknown. Recent studies have indicated that there is a positive relationship between Runx2 and the estrogen biosynthesis pathway. In this review, a possible functional link between Runx2 and estrogen synthesis pathway in skeletal tissues will be discusses as well as the biological significance of this interaction.

The effects of neuromuscular electrical stimulation on skeletal muscle architecture and qualitative properties in vivo

  • Lee, Jeong-Woo;Yoon, Se-Won
    • International Journal of Contents
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    • 제5권4호
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    • pp.35-39
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    • 2009
  • The purpose of this study was to evaluate the changes in skeletal muscle architecture and qualitative properties by muscle contraction force when neuromuscular electrical stimulation (NMES) of 50% MVIC was applied. Sixteen subjects (8 male, 8 female) without neuromuscular disease volunteered to participate in the study. All subjects were divided into two subgroups: control (no electrical stimulation) group and 50% maximal voluntary isometric contraction (MVIC) group. NMES training program was performed in the calf muscle three times a week for 10 weeks. Before and after the experiments, the MVIC of ankle plantar flexor was measured by the use of dynamometer, and the ultrasonography in the gastrocnemius medialis muscle was measured. The following results were obtained; MVIC was significantly increased in the electrical stimulation groups. Pennation angle, muscle density, and white area index also considerably changed in the electrical stimulation groups. In conclusion, the NMES training of 50% MVIC, comparative low level, improved the skeletal muscle architecture and the qualitative properties as well as the muscle contraction force.

자동차 유리제조사의 근골격계 질환 유해요인 조사 (An Ergonomic Research on Injurious Factirs Causing Musculoskeletal Disorders at an Automotive Glass Manufacturing Company)

  • 양성환;조문선;박범
    • 대한안전경영과학회:학술대회논문집
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    • 대한안전경영과학회 2005년도 춘계학술대회
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    • pp.251-257
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    • 2005
  • The purpose of this study is to execute the investigation of injurious factors causing muscle-skeletal diseases at an automotive glass manufacturing company and, on the basis of the results, to enhance productivity by the improvement of working environment. By using an survey and an ergonomic evaluation method, symptoms of muscle-skeletal diseases of workers and working postures at each process were analyzed, and quantitative evaluation of muscle-skeletal disease risk against each process was performed. Based on the result of the evaluation, to enhance the working environment, improvement of worktable, working space, tools, and outfit was suggested, and induction of mechanical system was also suggested. Suggested improvement plan was applied to the workplace step by step and it is confirmed that improvement plan not only removes the injurious factors of muscle-skeletal diseases but also is effective to enhance productivity.

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전치부 개방교합의 골격요소간 상호연관성에 관한 연구 (A STUDY OF CORRELATION ON THE SKELETAL FACTORS OF THE ANTERIOR OPEN BITE)

  • 김형일
    • 대한치과교정학회지
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    • 제15권2호
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    • pp.249-259
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    • 1985
  • To analyze the skeletal characteristics of the open bite, the faces of normal occlusion and open bite were measured using a cephalogram. The factors which were greatly different from normal occlusion were selected. The effects of these factors on the incisal overbite and correlation on these factors were studied. The following results were obtained: 1. The 13 factors which comprised the characteristics of the open bite were obtained. (Table 5) 2. The cause and amount of the open bite were dependent on the skeletal angulation than skeletal length. 3. For determining the incisal overbite, most highly correlated single factor was the interincisal angle. 4. The correlation on the selected 13 factors which comprised the characteristics of the open bite was obtained. (Table 6) 5. The open bite was due to combination of various factors than due to single factor. (Table 3,4).

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골격근의 구조와 생역학에 관한 고찰 (A Review of Structure and Biomechanics of the Skeletal Muscle)

  • 공원태
    • 대한정형도수물리치료학회지
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    • 제13권1호
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    • pp.58-66
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    • 2007
  • The purpose of this study is to understand the structure and biomechanics of the skeletal muscle. The skeletal muscle takes 40 to 45% of the whole body. Stable posture requires a balance of muscle. However, when the muscle strength is unbalanced, movement initiates. The power generated by the muscle is a primary means to adjust the equilibrium of posture and movement. The structural unit of the skeletal muscle is a long cylindrical type muscle fiber which contains hundreds of nucleus. The thickness of muscle fiber is about $10-100{\mu}m$, and its length is about 1-50cm. Muscle fiber is composed of myofibril that is covered with plasma membrane which is called sarcolemma. In understanding the movement of human body, it is important to comprehend the movement of bone and joint and the tension of muscle. Understanding the structure and biomechanics of muscle also provides basic information on clinical treatment of patients.

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선 자세에서의 인체 관절의 지각 불편도 측정 (Measurement on Perceived Human Body Joints Discomfort in the Standing Posture)

  • 기도형
    • 산업공학
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    • 제10권3호
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    • pp.197-208
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    • 1997
  • In workplace design, an ergonomic solution should ensure low postural stress in the operator during his/her work. Stress caused by awkward working postures of the trunk, shoulders and legs can result in fatigue, discomfort, musculo-skeletal disorders and nerve entrapment syndromes. Since discomfort and musculo-skeletal disorders are both related to exposure to biomechanical load on the musculo-skeletal system, minimization of discomfort will contribute to reduction of the risk for musculo-skeletal disorders as well. Therefore, in this study, perceived discomfort on the human body joints was measured in the standing postures using the magnitude estimation in order to have a standardized numerical scale for joint discomfort. Nine healthy graduate students participated voluntarily in the laboratory study. The results revealed that perceived discomfort of all the joints increased as the joints deviated from neutral position. Especially, it showed drastic increment on perceived discomfort when deviation from neutral position in each human body joint increased from 75% to 100%. in terms of relative range of motion(R0M). On the basis of these experimental results, a preliminary ranking for assessment of stressfulness of non-neutral postures around the human body joints was suggested.

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