• Biomolecules & Therapeutics
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• 제13권2호
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• pp.84-89
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• 2005

The purpose of this study was to characterize the putative anxiolytic-like effects of the aqueous extract of the root of Polygala tenuifolia ( AEPT) using an elevated plus maze (EPM) and hole-board apparatus in mice. The AFPT was orally administered at 50, 100, 200 or 400 mg/kg to ICR mice, 1 h before the behavioral evaluation in the EPM respectively. Control mice were treated with an equal volume of saline, and positive control mice with buspirone (2 mg/kg). Single treatments of the AEPT significantly increased the percentage of time spent and arm entries into the open arms of the EPM vedrsus saline controls (P<0.05). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with the saline controls. In the hole-board test,single treatments of the AEPT (200 and 400 mg/kg) significantly increased the number of headdips versus saline controls (P<0.05). In addition, the anxiolytic-like effects of the AEPT were blocked by WAY 100635(0.3mg/kg, I.p), a5-$HT_{1A}$ receptor antagonist not by flumazenil, a $GABA_{A}$ antagonist. These results indicate that P. tenuifolia is an effective anxiolytic agent, andsuggest that the anxiolytic-like effects of P. tenuifolia is mediated via the serotonergic nervous system.

• 한국가스학회지
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• 제25권6호
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• pp.22-28
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• 2021

발전용 가스터빈에 사용되는 이중 콘형 예혼합 연소기의 성능 개선 및 검증을 위하여 기존 노즐에서 연료 분사 특성을 개선한 노즐(분사구 직경 증가, 분사구 수 감소, 총 분사면적 유지)을 이용하여 고압 및 다중화염 조건에서 실험 연구를 수행하였으며 배기가스 특성을 기존 노즐과 비교하였다. 실험 결과로는 노즐의 연료 직경을 크게 한 경우 연소용 공기로 연료의 침투 거리가 증가하기 때문에 콘 내부에서 연료와 공기의 혼합특성이 개선되어 상압뿐만 아니라 압력 상승 시 NOx 배출 농도는 감소하며 다중 화염의 경우 화염간 연소영역의 중첩이 감소하게 되어 NOx 배출은 감소하지만 화염 안정성은 저하된다. 연료 분사구를 개선한 노즐의 발전 플랜트 실증 결과는 실험 결과와 같이 기존 노즐에 비하여 NOx 농도가 낮게 배출되었다.

• 설비공학논문집
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• 제16권6호
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• pp.589-598
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• 2004

Flow condensation heat transfer coefficients (HTCs) of R22 and R134a were measured on a horizontal 9 hole aluminum multi-channel tube. The main test section in the refrigerant loop was made of a flat multi-channel aluminum tube of 1.4 mm hydraulic diameter and 0.53 m length. Refrigerant was cooled by passing cold water through an annulus surrounding the test section. Data were obtained in the vapor qualities of 0.1∼0.9 at mass flux of 200∼400 kg/$m^2$s and heat flux of 7.3∼7.7 ㎾/$m^2$ at the saturation temperature of 4$0^{\circ}C$. All popular correlations in single-phase subcooled liquid and flow condensation originally developed for large single tubes predicted the present data of the flat tube within 20% deviation when effective heat transfer area is used in determining experimental data. This suggests that there is little change in flow characteristics and patterns when the tube diameter is reduced down to 1.4 mm diameter range. Thermal insulation for the outer tube section surrounding the test tube for the transport of heat transfer fluid is very important in fluid heat-ing or cooling type heat transfer experimental apparatus.

• 대한기계학회논문집B
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• 제23권8호
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• pp.1048-1062
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• 1999

A numerical method and experiments for the aerodynamic design of high performance two-stage axial flow fans was carried out. A vortex ring element method used for the aerodynamic analysis of the propellers was extended to the fan-duct system. Fan Performance and velocity profiles at the fan inlet and outlet are compared with experimental data for the validations of numerical method. Performance test was done based on KS B 6311(testing methods for turbo-fans and blowers). The velocity profile was obtained using a 5-hole pitot tube by the non-nulling method. The two stage axial flow fan configurations for the optimal operation conditions were set by using the experimental results for the single rotating axial flow fan and the single stage axial flow fan. The single rotating axial flow fan showed relatively low efficiency due to the swirl velocities behind rotor exit which produced pressure losses. In contrast, the single stage and the two-stage axial flow fans showed performance improvements due to the swirl velocity reduction by the stator. The peak efficiency of the two stage axial flow fan was improved by 21% and 6%, compared to the single rotating axial flow fan and the single stage axial flow fan, respectively.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2001년도 제22회 KOSCI SYMPOSIUM 논문집
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• pp.67-74
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• 2001

The annular-reverse combustor was designed for APU combustor and a three dimensional analysis for reactive flow in the combustor was performed. At the same time, the experimental work was performed in KARl combustor test facility. In this study we found out that tangential swirl type combustor is good for flame holding than single vortex type combustor. The flame tube main hole size and relative position are very important parameters for combustor general performance. The ignition characteristics are strongly depend on the air fuel ratio with combustor inlet volume flow ratio.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.211-216
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• 2001

The components with the circular cross section have the symmetric combination parts for rotating balance and the crack emanates from the symmetric combination parts. The symmetric cracks from symmetric combination parts make a decrease in the component fatigue life more than single crack. In this study, to estimate the behavior of symmetric cracks, the fatigue test was performed using rotary bending tester on the specimen with a symmetric defects in circular cross section. The material used in this study is Ni-Cr-Mo steel alloy. Under the same stress, the result from the rotary bending fatigue test turned out that the symmetric cracks made a decrease in the fatigue life by 35% more than single crack and the relation between log a and cycle ratio $N/N_f$ obtained linearly.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2002년도 학술대회지
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• pp.619-622
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• 2002

It has been recognized that the flow in the blade passage of an axial turbomachinery rotor is very complex and is influenced by various flow phenomena, of which the tip leakage flow passing through the gap between rotor blade tip and casing plays a significant role. The losses produced due to the existence of the clearance have been known to be a large contributor of the rotor overall losses. Despite several experimental studies on non-rotating blade in the cascade configuration, and on actual rotating blades, the detailed nature of the complex flow phenomena associated with tip leakage, however, remains largely unresolved. Thus, a single-stage compressor test rig was built and measurements were taken at upstream and downstream of the rotor of this compressor at the aerodynamics laboratory of University of New South Wales. A five-hole probe and a hot-wire probe were used to measure mean and fluctuating flow parameters. The results show that tip leakage losses rise rapidly beyond tip gap of 0.01 Furthermore, the present project also identifies the regions in the wake behind the rotor of the axial compressor where such losses are concentrated. These results should be useful in the better design of rotors for improved performance of axial compressor.

• International Journal of Precision Engineering and Manufacturing
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• 제5권4호
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• pp.36-42
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• 2004

The shaft with the circular cross section has symmetric structural combination parts to keep the rotating balance. Hence the crack usually initiates from symmetric combination parts due to the stress concentration of these parts. In this study to estimate the fatigue behavior of symmetric cracks, the fatigue test was performed by using a rotary bending tester and the specimen with symmetric defects in circular cross section. The characteristics of crack initiation and propagation on the symmetric surface cracks in circular cross section were examined. We also observed the internal crack using the oxidation coloring method and investigated the fatigue behavior using the relationship between the surface crack and the internal crack. As a result, the fatigue life of symmetric cracks was reduced by 35% compared to that of a single crack. We examined the characteristics of fatigue behavior of elements with symmetric cracks using internal crack propagation rate and maximum stress intensity factor range that were obtained from an approximation method.

• 지질공학
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• 제10권1호
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• pp.13-25
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• 2000

단열암반의 수리전도도 텐서를 계산하고 이방성에 대한 정량적인 평가를 수행하기 위해서 단열의 수리적, 기하학적 통계 특성에 근거하여 3차원 단열연결망 모델을 구성하였다. 현장에서 수행된 단정주입시험의 수치모델링을 통해 계산된 수리전도도는 현장시험 결과와 비교적 잘 일치하였다. 따라서 구성된 3차원 단열 연결망 모델이 해석대상 암반의 수리 특성을 구현할 수 있음을 확인하였다. 대상암반의 대표요소체적 규모에서 계산된 블록 수리전도도는 단정주입시험에서 구한 수리전도도의 산술과 조화 평균 사이의 값이며, 2차원 수평단면상에서 남-북 방향의 수리전도도는 동-서 방향에 비해서 약 1.4 배로써 이방성은 크지 않았다. 블록 수리전도도와 단정 주입시험 모델링을 통해 구한 수리전도도의 상관성은 낮게 나타났다. 이는 단정 주입시험 모델링을 통한 암반의 수리전도도는 시추공의 패커구간과 교차하는 단열의 수와 투수량계수에 큰 영향을 받기 때문인 것으로 분석된다.

• Journal of Korean Neurosurgical Society
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• 제37권2호
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• pp.96-100
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• 2005

Objective: The brain computed tomography(CT) is an important tool throughout the clinical course of chronic subdural hematoma(CSDH). In CT findings, the density of CSDH is different in each case. We analyze management options and results according to the density of CSDH. Methods: Seventy one patients with CSDH, who had been managed in our institute from August 2001 to December 2003, were reviewed retrospectively. The authors divided the patients into six groups according to the density of hematoma; Group A-hypodense rather than the brain parenchyma, group B-isodense, group C-hyperdense, group D-mixed with hypodense and hyperdense, group E-mixed with isodense and hypodense and group F-mixed with isodense and hypersdense. In each group, the operation method, the duration of the indwelling catheter and prognosis were analyzed. Results: The patients who showed mixed density were 39 and, those who showed single density were 32. All the patients underwent burr hole drainage for the primary choice. There was only two cases that needed additional craniotomy. The average duration of indwelling catheter was $5.40{\pm}1.91$ days. Statistically the duration was not different in each group(p-value<0.05, $x^2$ test). Three cases recurred, one in group C, another in group D, and the last in group E. It had no statistical significance due to low incidence of recurrence. Conclusion: We conclude that burr hole drainage is an acceptable primary treatment option for CSDH even though the density of hematoma is different in every single case.