• Biomolecules & Therapeutics
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• v.13 no.2
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• pp.84-89
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• 2005

The purpose of this study was to characterize the putative anxiolytic-like effects of the aqueous extract of the root of Polygala tenuifolia ( AEPT) using an elevated plus maze (EPM) and hole-board apparatus in mice. The AFPT was orally administered at 50, 100, 200 or 400 mg/kg to ICR mice, 1 h before the behavioral evaluation in the EPM respectively. Control mice were treated with an equal volume of saline, and positive control mice with buspirone (2 mg/kg). Single treatments of the AEPT significantly increased the percentage of time spent and arm entries into the open arms of the EPM vedrsus saline controls (P<0.05). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with the saline controls. In the hole-board test,single treatments of the AEPT (200 and 400 mg/kg) significantly increased the number of headdips versus saline controls (P<0.05). In addition, the anxiolytic-like effects of the AEPT were blocked by WAY 100635(0.3mg/kg, I.p), a5-$HT_{1A}$ receptor antagonist not by flumazenil, a $GABA_{A}$ antagonist. These results indicate that P. tenuifolia is an effective anxiolytic agent, andsuggest that the anxiolytic-like effects of P. tenuifolia is mediated via the serotonergic nervous system.

• Journal of the Korean Institute of Gas
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• v.25 no.6
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• pp.22-28
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• 2021

Combustion characteristics were examined experimentally for a swirl-stabilized double cone premixed burner nozzle used for industrial gas turbines for power generation. An original model and a variant with a different fuel injection pattern are tested to compare their combustion characteristics such as NOx, CO and stability in pressurized conditions with single burner-flame and in an ambient multi-flame conditions with multi-burners. Test results show that NOx emissions are smaller for the variant, whose number of fuel holes is reduced with the same total area of fuel holes, in ambient and pressurized single-flame conditions with single burner, which results from enhanced fuel/air mixing due to a higher penetration of fuel into the air stream. The multi-burnerflame test results show that NOx emissions are smaller for the variant due to reduced flame interactions, which, on the contrary, slightly reduces the stability margin. On-site test results fromin an actual power plants also show that NOx emissions are reduced for the variant, compared with the original one, which is in agreement with the lab test results stated above.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.16 no.6
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• pp.589-598
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• 2004

Flow condensation heat transfer coefficients (HTCs) of R22 and R134a were measured on a horizontal 9 hole aluminum multi-channel tube. The main test section in the refrigerant loop was made of a flat multi-channel aluminum tube of 1.4 mm hydraulic diameter and 0.53 m length. Refrigerant was cooled by passing cold water through an annulus surrounding the test section. Data were obtained in the vapor qualities of 0.1∼0.9 at mass flux of 200∼400 kg/$m^2$s and heat flux of 7.3∼7.7 ㎾/$m^2$ at the saturation temperature of 4$0^{\circ}C$. All popular correlations in single-phase subcooled liquid and flow condensation originally developed for large single tubes predicted the present data of the flat tube within 20% deviation when effective heat transfer area is used in determining experimental data. This suggests that there is little change in flow characteristics and patterns when the tube diameter is reduced down to 1.4 mm diameter range. Thermal insulation for the outer tube section surrounding the test tube for the transport of heat transfer fluid is very important in fluid heat-ing or cooling type heat transfer experimental apparatus.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.23 no.8
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• pp.1048-1062
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• 1999

A numerical method and experiments for the aerodynamic design of high performance two-stage axial flow fans was carried out. A vortex ring element method used for the aerodynamic analysis of the propellers was extended to the fan-duct system. Fan Performance and velocity profiles at the fan inlet and outlet are compared with experimental data for the validations of numerical method. Performance test was done based on KS B 6311(testing methods for turbo-fans and blowers). The velocity profile was obtained using a 5-hole pitot tube by the non-nulling method. The two stage axial flow fan configurations for the optimal operation conditions were set by using the experimental results for the single rotating axial flow fan and the single stage axial flow fan. The single rotating axial flow fan showed relatively low efficiency due to the swirl velocities behind rotor exit which produced pressure losses. In contrast, the single stage and the two-stage axial flow fans showed performance improvements due to the swirl velocity reduction by the stator. The peak efficiency of the two stage axial flow fan was improved by 21% and 6%, compared to the single rotating axial flow fan and the single stage axial flow fan, respectively.

• 한국연소학회:학술대회논문집
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• 2001.06a
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• pp.67-74
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• 2001

The annular-reverse combustor was designed for APU combustor and a three dimensional analysis for reactive flow in the combustor was performed. At the same time, the experimental work was performed in KARl combustor test facility. In this study we found out that tangential swirl type combustor is good for flame holding than single vortex type combustor. The flame tube main hole size and relative position are very important parameters for combustor general performance. The ignition characteristics are strongly depend on the air fuel ratio with combustor inlet volume flow ratio.

• Proceedings of the KSME Conference
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• 2001.06a
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• pp.211-216
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• 2001

The components with the circular cross section have the symmetric combination parts for rotating balance and the crack emanates from the symmetric combination parts. The symmetric cracks from symmetric combination parts make a decrease in the component fatigue life more than single crack. In this study, to estimate the behavior of symmetric cracks, the fatigue test was performed using rotary bending tester on the specimen with a symmetric defects in circular cross section. The material used in this study is Ni-Cr-Mo steel alloy. Under the same stress, the result from the rotary bending fatigue test turned out that the symmetric cracks made a decrease in the fatigue life by 35% more than single crack and the relation between log a and cycle ratio $N/N_f$ obtained linearly.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.619-622
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• 2002

It has been recognized that the flow in the blade passage of an axial turbomachinery rotor is very complex and is influenced by various flow phenomena, of which the tip leakage flow passing through the gap between rotor blade tip and casing plays a significant role. The losses produced due to the existence of the clearance have been known to be a large contributor of the rotor overall losses. Despite several experimental studies on non-rotating blade in the cascade configuration, and on actual rotating blades, the detailed nature of the complex flow phenomena associated with tip leakage, however, remains largely unresolved. Thus, a single-stage compressor test rig was built and measurements were taken at upstream and downstream of the rotor of this compressor at the aerodynamics laboratory of University of New South Wales. A five-hole probe and a hot-wire probe were used to measure mean and fluctuating flow parameters. The results show that tip leakage losses rise rapidly beyond tip gap of 0.01 Furthermore, the present project also identifies the regions in the wake behind the rotor of the axial compressor where such losses are concentrated. These results should be useful in the better design of rotors for improved performance of axial compressor.

• International Journal of Precision Engineering and Manufacturing
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• v.5 no.4
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• pp.36-42
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• 2004

The shaft with the circular cross section has symmetric structural combination parts to keep the rotating balance. Hence the crack usually initiates from symmetric combination parts due to the stress concentration of these parts. In this study to estimate the fatigue behavior of symmetric cracks, the fatigue test was performed by using a rotary bending tester and the specimen with symmetric defects in circular cross section. The characteristics of crack initiation and propagation on the symmetric surface cracks in circular cross section were examined. We also observed the internal crack using the oxidation coloring method and investigated the fatigue behavior using the relationship between the surface crack and the internal crack. As a result, the fatigue life of symmetric cracks was reduced by 35% compared to that of a single crack. We examined the characteristics of fatigue behavior of elements with symmetric cracks using internal crack propagation rate and maximum stress intensity factor range that were obtained from an approximation method.

• The Journal of Engineering Geology
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• v.10 no.1
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• pp.13-25
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• 2000

A three-dimensional discrete fracture network model based on probabilistic characteristics of fracture geometry and transmissivity was designed to calculate the conductivity tensor and to estimate theanisotropy of conductivity. The conductivities, $K_p$, obtained from the numerical simulation of single-holepacker test corresponded well to those from the field tests. From this, it can be concluded that thefracture network model designed in this study can represent hydraulic characteristics of in-situ fractured rock mass. Block-scale conductivities, $K_b$, estimated from the modelling of steady-state flow through the REV-scale block were ranged between the arithmetic mean and harmonic mean of theconductivity estimates from packer tests. The conductivity along north-south direction was 1.4 timesgreater than that along the east-west direction. It was concluded that the anisotropy of conductivitywas insignificant. It was also found that there was a little correlation between $K_b$ and $K_p$. This would be to that the conductivities from the packer test simulation was strongly dependent on thetransmissivity and the number of fractures within the packer test intervals.

• Journal of Korean Neurosurgical Society
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• v.37 no.2
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• pp.96-100
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• 2005

Objective: The brain computed tomography(CT) is an important tool throughout the clinical course of chronic subdural hematoma(CSDH). In CT findings, the density of CSDH is different in each case. We analyze management options and results according to the density of CSDH. Methods: Seventy one patients with CSDH, who had been managed in our institute from August 2001 to December 2003, were reviewed retrospectively. The authors divided the patients into six groups according to the density of hematoma; Group A-hypodense rather than the brain parenchyma, group B-isodense, group C-hyperdense, group D-mixed with hypodense and hyperdense, group E-mixed with isodense and hypodense and group F-mixed with isodense and hypersdense. In each group, the operation method, the duration of the indwelling catheter and prognosis were analyzed. Results: The patients who showed mixed density were 39 and, those who showed single density were 32. All the patients underwent burr hole drainage for the primary choice. There was only two cases that needed additional craniotomy. The average duration of indwelling catheter was $5.40{\pm}1.91$ days. Statistically the duration was not different in each group(p-value<0.05, $x^2$ test). Three cases recurred, one in group C, another in group D, and the last in group E. It had no statistical significance due to low incidence of recurrence. Conclusion: We conclude that burr hole drainage is an acceptable primary treatment option for CSDH even though the density of hematoma is different in every single case.