• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.17 no.4
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• pp.410-414
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• 2004

High throughput analysis using a DNA chip microarray is powerful tool in the post genome era. Less labor-intensive and lower cost-performance is required. Thus, this paper aims to develop the multi-channel type label-free DNA chip and detect SNP (Single nucleotide polymorphisms). At first, we fabricated a high integrated type DNA chip array by lithography technology. Various probe DNAs were immobilized on the microelectrode array. We succeeded to discriminate of DNA hybridization between target DNA and mismatched DNA on microarray after immobilization of a various probe DNA and hybridization of label-free target DNA on the electrodes simultaneously. This method is based on redox of an electrochemical ligand.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2006.06a
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• pp.410-411
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• 2006

High throughput analysis using a DNA chip microarray is powerful tool in the post genome era. Less labor-intensive and lower cost-performance is required. Thus, this paper aims to develop the multi-channel type label-free DNA chip and detect SNP (Single nucleotide polymorphisms). At first, we fabricated a high integrated type DNA chip array by lithography technology. Various probe DNAs were immobilized on the microelectrode array. We succeeded to discriminate of DNA hybridization between target DNA and mismatched DNA on microarray after immobilization of a various probe DNA and hybridization of label-free target DNA on. the electrodes simultaneously. This method is based on redox of an electrochemical ligand.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.07b
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• pp.845-848
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• 2004

High throughput analysis using a DNA chip microarray is powerful tool in the post genome era. Less labor-intensive and lower cost-performance is required. Thus, this paper aims to develop the multi-channel type label-free DNA chip and detect SNP (Single nucleotide polymorphisms). At first, we fabricated a high integrated type DNA chip array by lithography technology. Various probe DNAs were immobilized on the microelectrode array. We succeeded to discriminate of DNA hybridization between target DNA and mismatched DNA on microarray after immobilization of a various probe DNA and hybridization of label-free target DNA on the electrodes simultaneously. This method is based on redox of an electrochemical ligand.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.549-549
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• 2012

Early detection of cancer biomarkers in the blood is of vital importance for reducing the mortality and morbidity in a number of cancers. From this point of view, immunosensors based on nanowire (NW) and carbon nanotube (CNT) field-effect transistors (FETs) that allow the ultra-sensitive, highly specific, and label-free electrical detection of biomarkers received much attention. Nevertheless 1D nano-FET biosensors showed high performance, several challenges remain to be resolved for the uncomplicated, reproducible, low-cost and high-throughput nanofabrication. Recently, two-dimensional (2D) graphene and reduced GO (RGO) nanosheets or films find widespread applications such as clean energy storage and conversion devices, optical detector, field-effect transistors, electromechanical resonators, and chemical & biological sensors. In particular, the graphene- and RGO-FETs devices are very promising for sensing applications because of advantages including large detection area, low noise level in solution, ease of fabrication, and the high sensitivity to ions and biomolecules comparable to 1D nano-FETs. Even though a limited number of biosensor applications including chemical vapor deposition (CVD) grown graphene film for DNA detection, single-layer graphene for protein detection and single-layer graphene or solution-processed RGO film for cell monitoring have been reported, development of facile fabrication methods and full understanding of sensing mechanism are still lacking. Furthermore, there have been no reports on demonstration of ultrasensitive electrical detection of a cancer biomarker using the graphene- or RGO-FET. Here we describe scalable and facile fabrication of reduced graphene oxide FET (RGO-FET) with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}$ 1-antichymotrypsin (PSA-ACT) complex, in which the ultrathin RGO channel was formed by a uniform self-assembly of two-dimensional RGO nanosheets, and also we will discuss about the immunosensing mechanism.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.7C
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• pp.652-657
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• 2007

Optical subcarrier-multiplexed (OSCM) labels in optical label switching networks have been detected using interleavers composed of fiber-optic Mach-Zehnder interferometer. 10-GHz optical single-/double-sideband signals generated from dual-electrode Mach-Zehnder intensity modulator have been used as the OSCM labels. In the case of single-sideband signals, the upper-sideband was observed to be suppressed about 16.8 dB compared with the lower-sideband from the optical spectrum measured at the label extraction output. For the case of double-sideband signals, both sidebands appeared with small insertion loss at the interleaver output. Since we used the phase-shift method to generate single-sideband signals, the power level of the single-sideband was higher by 3 dB than that of the double-sidebands.

• Journal of the Korean Society for information Management
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• v.35 no.2
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• pp.37-62
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• 2018

This study examined the factors affecting the performance of automatic classification based on machine learning for domestic journal articles in the field of LIS. In particular, In view of the classification performance that assigning automatically the class labels to the articles in "Journal of the Korean Society for Information Management", I investigated the characteristics of the key factors(weighting schemes, training set size, classification algorithms, label assigning methods) through the diversified experiments. Consequently, It is effective to apply each element appropriately according to the classification environment and the characteristics of the document set, and a fairly good performance can be obtained by using a simpler model. In addition, the classification of domestic journals can be considered as a multi-label classification that assigns more than one category to a specific article. Therefore, I proposed an optimal classification model using simple and fast classification algorithm and small learning set considering this environment.

• Journal of the Korean Society for information Management
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• v.33 no.2
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• pp.33-59
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• 2016

This study examined the factors affecting the performance of automatic classification for the domestic conference papers based on machine learning techniques. In particular, In view of the classification performance that assigning automatically the class labels to the papers in Proceedings of the Conference of Korean Society for Information Management using Rocchio algorithm, I investigated the characteristics of the key factors (classifier formation methods, training set size, weighting schemes, label assigning methods) through the diversified experiments. Consequently, It is more effective that apply proper parameters (${\beta}$, ${\lambda}$) and training set size (more than 5 years) according to the classification environments and properties of the document set. and If the performance is equivalent, I discovered that the use of the more simple methods (single weighting schemes) is very efficient. Also, because the classification of domestic papers is corresponding with multi-label classification which assigning more than one label to an article, it is necessary to develop the optimum classification model based on the characteristics of the key factors in consideration of this environment.

• Information Systems Review
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• v.22 no.3
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• pp.81-97
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• 2020

Recent trends in sentiment analysis have been focused on applying single label classification approaches. However, when considering the fact that a review comment by one person is usually composed of several topics or aspects, it would be better to classify sentiments for those aspects respectively. This paper has two purposes. First, based on the fact that there are various aspects in one sentence, aspect mining is performed to classify the emotions by each aspect. Second, we apply the multiple label classification method to analyze two or more dependent variables (output values) at once. To prove our proposed approach's validity, online review comments about musical performances were garnered from domestic online platform, and the multi-label classification approach was applied to the dataset. Results were promising, and potentials of our proposed approach were discussed.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2003.11a
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• pp.224-226
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• 2003

In this paper, we succeeded SNP discrimination of DNA hybridization on microarray using new electrochemical system. Using the electrochemical method with a label-free DNA has Performed DNA chip microarray. This method is based on redox of an electrochemical ligand. We developed scanning system with high performance.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.3
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• pp.191-198
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• 2016

Traceability is essential in modern automotive manufacturing. Among existing technologies, RFID is the most promising choice for this purpose. However, due to the harsh conditions of production lines, especially in the paint shop, automobile OEMs would require expensive dedicated RFID tags and readers, which are incompatible with standard RFID technologies. Unlike the manufacturing industry, the logistics industry uses UHF label tags for track and trace, which provides high performance and a low price. Recently, this technology has improved to the extent that it can be used in harsh conditions such as on metal parts or in liquid. Herein, we assess the technical, operational, and economic feasibility of UHF label-tag technology for seamless end-toend traceability. Based on prototyping, lab/field tests, and cost-benefit analysis, we have proven that the single disposable UHF tags can successfully replace the problematic and expensive tags used in most domestic automobile OEMs today.