• Korean Journal of Radiology
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• v.24 no.4
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• pp.284-293
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• 2023

Objective: To validate a simplified ordinal scoring method, referred to as modified length-based grading, for assessing coronary artery calcium (CAC) severity on non-electrocardiogram (ECG)-gated chest computed tomography (CT). Materials and Methods: This retrospective study enrolled 120 patients (mean age ± standard deviation [SD], 63.1 ± 14.5 years; male, 64) who underwent both non-ECG-gated chest CT and ECG-gated cardiac CT between January 2011 and December 2021. Six radiologists independently assessed CAC severity on chest CT using two scoring methods (visual assessment and modified length-based grading) and categorized the results as none, mild, moderate, or severe. The CAC category on cardiac CT assessed using the Agatston score was used as the reference standard. Agreement among the six observers for CAC category classification was assessed using Fleiss kappa statistics. Agreement between CAC categories on chest CT obtained using either method and the Agatston score categories on cardiac CT was assessed using Cohen's kappa. The time taken to evaluate CAC grading was compared between the observers and two grading methods. Results: For differentiation of the four CAC categories, interobserver agreement was moderate for visual assessment (Fleiss kappa, 0.553 [95% confidence interval {CI}: 0.496-0.610]) and good for modified length-based grading (Fleiss kappa, 0.695 [95% CI: 0.636-0.754]). The modified length-based grading demonstrated better agreement with the reference standard categorization with cardiac CT than visual assessment (Cohen's kappa, 0.565 [95% CI: 0.511-0.619 for visual assessment vs. 0.695 [95% CI: 0.638-0.752] for modified length-based grading). The overall time for evaluating CAC grading was slightly shorter in visual assessment (mean ± SD, 41.8 ± 38.9 s) than in modified length-based grading (43.5 ± 33.2 s) (P < 0.001). Conclusion: The modified length-based grading worked well for evaluating CAC on non-ECG-gated chest CT with better interobserver agreement and agreement with cardiac CT than visual assessment.

• Journal of the Korean Society of Marine Environment & Safety
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• v.19 no.3
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• pp.290-301
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• 2013

The docking analysis of a global ship structure is requested to evaluate its structural safety against the reaction forces at supports during docking works inside a dry dock. That problem becomes more important recently as the size of ships is getting larger and larger. The docking supports are appropriately arranged in a dock to avoid their excessive reaction forces which primarily cause the structural damages in docking a ship and, up to now, the structural safety has been assessed against the support arrangement by the finite element analysis (FEA) of a global ship structure. However, it is complicated to establish the finite element model of the ship in the current structural design environment of a shipyard and it takes over a month to finish the work. This paper investigates a simple and fast approach to carry out a ship docking analysis by a simplified grillage model and to assign the docking supports position on the model. The grillage analysis was considered from the motivation that only the reaction forces at supports are sufficient to assess their arrangement. Since the simplified grillage model of the ship cannot guarantee its accuracy quantitatively, modeling strategies are proposed to improve the accuracy. In this paper, comparisons between the proposed approach and three-dimensional FEA for typical types of ships show that the results from the present grillage model have reasonably good agreement with the FEA model. Finally, an integrated program developed for docking supports planning and its evaluation by the proposed approach is briefly described.

• Structural Engineering and Mechanics
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• v.74 no.6
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• pp.821-832
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• 2020

The fundamental period is an important parameter for seismic design and seismic risk assessment of building structures. In this paper, a simplified theoretical method to predict the fundamental period of masonry infilled reinforced concrete (RC) frame is developed based on the basic theory of engineering mechanics. The different configurations of the RC frame as well as masonry walls were taken into account in the developed method. The fundamental period of the infilled structure is calculated according to the integration of the lateral stiffness of the RC frame and masonry walls along the height. A correction coefficient is considered to control the error for the period estimation, and it is determined according to the multiple linear regression analysis. The corrected formula is verified by shaking table tests on two masonry infilled RC frame models, and the errors between the estimated and test period are 2.3% and 23.2%. Finally, a probability-based method is proposed for the corrected formula, and it allows the structural engineers to select an appropriate fundamental period with a certain safety redundancy. The proposed method can be quickly and flexibly used for prediction, and it can be hand-calculated and easily understood. Thus it would be a good choice in determining the fundamental period of RC frames infilled with masonry wall structures in engineering practice instead of the existing methods.

• Journal of the Korean Solar Energy Society
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• v.32 no.2
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• pp.19-27
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• 2012

This paper describes an experimental study on efficiency of solar collector in solar water heating system connected to hourly water heating load. In general, the functional form of solar efficiency is expressed as a function of fluid temperature entering solar collector, ambient temperature, and solar irradiance. When energy saving from solar heating of water heating system is analyzed on along-term basis such as one year with given solar irradiance data, simplified analysis is more convenient han detailed system simulation for quick assessment. However, the functional form of the efficiency is not convenient for approximately simplified energy analysis because the inlet temperature can be obtained through a detailed system simulation. In the study, solar collector efficiency is obtained with various daily water heating load sand daily solar irradiance using experimental tests. The study also considers large residential buildings such as apartment buildings for application of solar water heating systems. From test results, it is found that daily solar collector efficiency is proportional to daily water heating loads and daily solar irradiance. The data obtained from the study can be utilized to find a functional relation between daily solar irradiance and daily heating load in stead of collector inlet temperature for application of solar collector efficiency to long-term approximated energy analysis of solar heating system.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.2B
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• pp.147-154
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• 2011

Physical habitat assessment models based on Instream Flow Incremental Methodology have been developed as a decision making tool to estimate appropriate discharge for environmental flow and water use management. These models, however, require extensive knowledge on various academic disciplines, complicated input data, and empirical data. We propose a Simplified Habitat (SIMHAB) simulation model for the estimation of physical structure of fish habitat and environmental flow at the planning stage. SIMHAB is applied to a river system for which physical and ecological data are available, and its applicability is investigated. Simulated results appeared to be similar to field survey data and those of such models as PHABSIM and River2D. However, SIMHAB requires much less input data. As such, the proposed model, SIMHAB can easily be applicable to river restoration projects including designing of physical habitat, estimation of environmental flow, and water resource management.

• Ocean and Polar Research
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• v.29 no.4
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• pp.391-400
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• 2007

To identify the spatial distribution pattern of water quality in Masan Bay, Pearson's correlation as a common statistic method and Moran's I as a spatial autocorrelation statistics were applied to the hydrological data seasonally collected from Masan Bay for two years ($2004{\sim}2005$). Spatial distribution of salinity, DO and silicate among the hydrological parameters clustered strongly while chlorophyll a distribution displayed a weak clustering. When the similarity matrix of Moran's I was compared with correlation matrix of Pearson's r, only the relationships of temperature vs. salinity, temperature vs. silicate and silicate vs. total inorganic nitrogen showed significant correlation and similarity of spatial clustered pattern. Considering Pearson's correlation and the spatial autocorrelation results, water quality distribution patterns of Masan Bay were conceptually simplified into four types. Based on the simplified types, Moran's I and Pearson's r were compared respectively with spatial distribution maps on salinity and silicate with a strong clustered pattern, and with chlorophyll a having no clustered pattern. According to these test results, spatial distribution of the water quality in Masan Bay could be summed up in four patterns. This summation should be developed as spatial index to be linked with pollutant and ecological indicators for coastal health assessment.

• Acute and Critical Care
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• v.33 no.4
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• pp.216-221
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• 2018

Background: In this study, we analyze the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II, APACHE IV, Simplified Acute Physiology Score (SAPS) 3, and Mortality Probability Model $(MPM)_0$ III in order to determine which system best implements data related to the severity of medical intensive care unit (ICU) patients. Methods: The present study was a retrospective investigation analyzing the discrimination and calibration of APACHE II, APACHE IV, SAPS 3, and $MPM_0$ III when used to evaluate medical ICU patients. Data were collected for 788 patients admitted to the ICU from January 1, 2015 to December 31, 2015. All patients were aged 18 years or older with ICU stays of at least 24 hours. The discrimination abilities of the three systems were evaluated using c-statistics, while calibration was evaluated by the Hosmer-Lemeshow test. A severity correction model was created using logistics regression analysis. Results: For the APACHE IV, SAPS 3, $MPM_0$ III, and APACHE II systems, the area under the receiver operating characteristic curves was 0.745 for APACHE IV, resulting in the highest discrimination among all four scoring systems. The value was 0.729 for APACHE II, 0.700 for SAP 3, and 0.670 for $MPM_0$ III. All severity scoring systems showed good calibrations: APACHE II (chi-square, 12.540; P=0.129), APACHE IV (chi-square, 6.959; P=0.541), SAPS 3 (chi-square, 9.290; P=0.318), and $MPM_0$ III (chi-square, 11.128; P=0.133). Conclusions: APACHE IV provided the best discrimination and calibration abilities and was useful for quality assessment and predicting mortality in medical ICU patients.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.270-272
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• 2022

Safety is one of the factors that prevent clinical drugs from being distributed on the market. In the case of neurotoxicity, which is the main cause of safety problems caused by drug side effects, risk assessment of drugs and compounds is required in advance. Currently, experiments for testing drug safety are based on animal experimetns, which have the disadvantage of being time-consuming and expensive. Therefore in order to solve the above problem, a neurotoxic prediction model through an in silico experiment was suggested. In this study, the category of neurotoxicity was expanded using a unified medical language system and various related compound data were obtained based on an integrated database. The SMILES (Simplified Molecular Input Line Entry System) of the obtained compounds were converted into fingerprints and it is used as input of machine learning. The model finally predicts the presence or absence of neurotoxicity. The experiment proposed in this study can reduce the time and cost required for the in vivo experiment. Furthermore, it is expected to shorten the research period for new drug development and reduce the burden of suspension of development.

• Journal of the Korea Concrete Institute
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• v.26 no.3
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• pp.351-360
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• 2014

The purpose of this research is to introduce the simplified equivalent frame model for the equivalent lateral force procedure, the response spectrum procedure and nonlinear procedure according to ASCE7-10 in order to reduce the time of performance and reasonably evaluate the effect of applying the damping system with the various conditions for the analysis and the variable. In this research, the seismic performance assessment and the design of the damping system were conducted through the nonlinear time history analysis based on the performance based seismic design in ASCE7-10 in regard to applying the damping system to apartment buildings which is lately issued. The optimal design based on the 75% of seismic base shear was performed for an apartment building. The seismic performance assessment were conducted to check the safety of the building, and the economic evaluation was performed by comparing the amount of resource for the optimal designed building with the amount of resource for the original building. In addition, hysteresis dampers was applied to the apartment building, and the suggested equivalent frame model was performed using the damping system design in ASCE7-10, then its control effects were proved in the full scale model of the apartment building which was used in this research.

• Journal of Korea Water Resources Association
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• v.56 no.10
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• pp.667-678
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• 2023

In this study, quasi-3D inundation flow simulations were conducted for a simplified subway station configuration. The effects of variations in rainwater inflow locations and discharge were investigated, analyzing the resulting inundation flow patterns and flood risk. The inundation simulation results calculated the incipient velocities for slipping and toppling accidents to assess pedestrian safety. The results indicated that velocities exceeding the incipient velocity for slipping accidents mainly occurred on the flooded staircase. Meanwhile, velocities surpassing the incipient toppling accidents were observed around the staircase and the corridor near the staircase leading to B2F. This observation is consistent with the results from the specific force distribution analysis. To provide detailed flood risk assessments, the Flood Hazard Degree (FD) was applied with four levels of criteria, along with the Flood Intensity Factor (FIF). The results demonstrated that FD identified a broader area at risk of flood-induced consequences compared to FIF. When comparing the different inundation risk assessment methods, the specific force method tended to overestimate the risk area, whereas FIF tended to underestimate it. Furthermore, among all assessment methods, the influence of rainwater discharge was found to have a more dominant effect on flood risk assessment compared to the number of rainwater inflow locations. Additionally, the direction of inundation flow influenced the assessed risk, with collision-induced flow patterns leading to higher flood risk than those with identical flow directions.