• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 1998년도 춘계종합학술대회
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• pp.365-370
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• 1998

The portable two way radio telephone amongst GMDSS equipment in the vessel is very important portable wireless one for search and rescue in distress situation. Although the portable two way radio telephone must be equipped with in the vessel by IMO RR, other kinds of wireless tranceivers are widely used to communicate with crew members who are separately appointed at bridge forecastle and poop in leaving or arriving at the port, passing through a narrow canal or voyaging in the foggy weather. Most of those wireless tranceivers except portable two way radio telephone are allocated at 27MHz band with PTT simplex system that makes crew members difficult to work effectively in the vessel. In this research 900MHz band FDD(frequency duplex division) tranceiver system is studied to help crew members in the vessel to communicate with themselves freely and to work easily meanwhile with simple operation. 900MHz band FDD tranceiver system uses one chip FM frontend IC to realize the miniaturization and downsizing of tranceiver and small size head set attached to helmet. The credibility of this research's result is highly evaluated by circuit analysis with computer aided simulation. and partly modified 900MHz band cordless phone circuit.

• 한국소음진동공학회논문집
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• 제12권12호
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• pp.935-942
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• 2002

When designing fluid mounts, design parameters can be varied in order to obtain a desired notch frequency and notch depth. The notch frequency is a function of the mount parameters and is typically selected by the designer to occur at the vibration disturbance frequency. Since the process of choosing these parameters can involve some trial and error, it seems to be a great application for obtaining optimal performance of the mount. Many combinations of parameters are possible to give us the desired notch frequency, but the question is which combination provides the lowest depth. Therefore. an automatic optimal technique is needed to optimize the performance of the fluid mount. In this study. the enhanced genetic algorithm (EGA) is applied to minimizing transmissibility of a fluid mount at the desired notch frequency, and at the notch and resonant frequencies. The EGA is modified genetic algorithm to search global and local optimal solutions of multi-modal function optimization. Furthermore. to reduce the searching time as compare to conventional genetic algorithm and Increase the precision of the solutions, the modified simplex method is combined with the algorithm. The results show that the performance of the optimized mount by using the hybrid algorithm is better than that of the conventional fluid mount.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 춘계학술대회논문집
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• pp.164-170
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• 2006

본 연구는 유전 알고리듬, 타부탐색법 그리고 반응표면법등 최근 많이 사용하고 있는 프로그램들의 장점들을 결합한 새로운 조합 유전 알고리듬을 제안한다. 본 알고리듬은 반응표면법 및 심플렉스법을 사용하여 유전알고리듬의 약점으로 여겨지는 수렴속도를 항상시키도록 하였다. 또한 유전 알고리듬에서 램덤한 다양성을 제공하지만, 본 연구에서는 타부리스트를 이용하여 체계적인 다양성을 추구하도록 하였다. 그리고 전통적인 시험함수에 본 알고리듬을 적용함으로써 본 방법의 효율성을 입증하였고 그 결과를 유전 알고리듬의 결과와 비교하였다. 또한 새롭게 제안된 알고리듬을 선미부에 위치한 청수탱크의 중량최적화에 적용한 길과 전역최적해를 효율적으로 찾는 것을 입증하였다. 또한 반응표면법을 사용한 새로운 유전알고리듬의 경우 실제 추가적인 목적함수를 평가하기 위한 계산이 필요 없으므로 수렴속도가 일반 유전 알고리듬보다 향상 되었음을 알 수 있었다. 마지막으로 제안된 조합 유전 알고리듬은 전역탐색능력과 수렴속도 측면에서 매우 강력한 전역 최적화 알고리듬임을 알 수 있었다.

• 한국소음진동공학회논문집
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• 제16권6호
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• pp.665-673
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• 2006

이 연구는 유전 알고리듬, 타부탐색법 그리고 반응표면법등 최근 많이 사용하고 있는 프로그램들의 장점들을 결합한 새로운 조합 유전 알고리듬을 제안한다. 이 알고리듬은 반응표면법 및 심플렉스법을 사용하여 유전알고리듬의 약점으로 여겨지는 수렴속도를 항상 시키도록 하였다. 또한 유전 알고리듬에서 램덤 한 다양성을 제공하지만, 이 연구에서는 타부리스트를 이용하여 체계적인 다양성을 추구하도록 하였다. 그리고 전통적인 시함함수에 본 알고리듬을 적용함으로써 이 방법의 효율성을 입증하였고 그 결과를 유전 알고리듬의 결과와 비교하였다. 또한 새롭게 제안된 알고리듬을 선미부에 위치한 청수탱크의 중량최적화에 적용한 결과 전역 최적해를 효율적으로 찾는 것을 입증하였다. 또한 반응표면법을 사용한 새로운 유전알고리듬의 경우 실제 추가적인 목적함수를 평가하기 위한 계산이 필요 없으므로 수렴속도가 일반 유전 알고리듬보다 향상되었음을 알 수 있었다. 마지막으로 제안된 조합 유전 알고리듬은 전역탐색능력과 수렴속도 측면에서 매우 강력한 전역 최적화 알고리듬임을 알 수 있었다.

• 품질경영학회지
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• 제48권2호
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• pp.269-282
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• 2020

Purpose: The practical design for experiments with mixtures of q components is consisted in the four types of design points, vertex, center of edge, axial, and center points in a (q-1)-dimensional simplex space. We propose a sequential method for the successful construction of the design space in Quality by Design (QbD) by allowing the different number of replicates at the four types of design points in the practical design when the quadratic canonical polynomial model is assumed. Methods: To compare the mixture designs efficiency, fraction of design space (FDS) plot is used. We search for the practical mixture designs whose the minimal half-width of the tolerance interval per a standard deviation, which is denoted as d₂, is less than 4.5 at 0.8 fraction of the design space. They are found by adding the different number of replicates at the four types of the design points in the practical design. Results: The practical efficient mixture designs for the number of components between three and five are listed. The sequential method to establish a design space is illustrated with the two examples based on the simulated data. Conclusion: The designs with the center of edge points replications are more efficient than those with the vertex points replication. We propose the sample size of at least 23 for three components, 28 for four components, and 33 for the five components based on the list of efficient mixture designs.

• IMMUNE NETWORK
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• 제5권2호
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• pp.89-98
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• 2005

Background: DNA vaccination represents an anticipated approach for the control of numerous infectious diseases. Used alone, however, DNA vaccine is weak immunogen inferior to viral vectors. In recent, heterologous prime-boost vaccination leads DNA vaccines to practical reality. Methods: We assessed prime-boost immunization strategies with a DNA vaccine (minigene, $gB_{498-505}$ DNA) and recombinant vaccinia virus $(vvgB_{498-505})$ expressing epitope $gB_{498-505}$ (SSIEF ARL) of CD8+ T cells specific for glycoprotein B (gB) of herpes simplex virus (HSV). Animals were immunized primarily with $gB_{498-505}$ epitope-expressing DNA vaccine/recombinant vaccinia virus and boosted with alternative vaccine type expressing entire Ag. Results: In prime-boost protocols using vvgBw (recombinant vaccinia virus expressing entire Ag) and $vvgB_{498-505}$, CD8+ T cell-mediated immunity was induced maximally at both acute and memory stages if primed with vvgBw and boosted with $vvgB_{498-505}$ as evaluated by CTL activity, intracellular IFN-staining, and MHC class I tetramer staining. Similarly $gB_{498-505}$ DNA prime-gBw DNA (DNA vaccine expressing entire Ag) boost immunization elicited the strongest CD8+ T cell responses in protocols based on DNA vaccine. However, the level of CD8+ T cell-mediated immunity induced with prime-boost vaccination using DNA vaccine expressing epitope or entire Ag was inferior to those based on vvgBw and $vvgB_{498-505}$. Of particular interest CD8+ T cell-mediated immunity was optimally induced when $vvgB_{498-505}$ was used to prime and gB DNA was used as alternative boost. Especially CD7+ T cell responses induced by such protocol was longer lasted than other protocols. Conclusion: These facts direct to search for the effective strategy to induce optimal CD8+ T cell-mediated immunity against cancer and viral infection.