• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.23 no.1
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• pp.224-252
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• 2010

Objective : The purpose of this study is to investigate tinnitus of Plain Questions $\ll$素問$\gg$ and Miraculous Pivot $\ll$靈樞$\gg$. Methods : We conducted a study on the original text paragraphs of Internal Classic $\ll$內經$\gg$ containing the tinnitus and analysis of Yang, Ma, Zhang, Wang etc. We drew a parallel between tinnitus from Internal Classic $\ll$內經$\gg$ and matching diagnoses from western medicine. Results : The results were as follows. 1. Tinnitus in Plain Questions $\ll$素問$\gg$Tong Pyeong Heo Sil Ron <通評虛實論> was similar to the symptoms of diabetes mellitus complication and schizophreniform disorder in western medicine. 2. Liver fire tinnitus in Plain Questions $\ll$素問$\gg$ Yuk Won Jeong Gi Dae Ron <六元正紀大論> was similar to the symptoms of psychological distress in western medicine. 3. Phlegm fire tinnitus in Plain Questions $\ll$素問$\gg$ Ji Jin Yo Dae Ron <至眞要大論> was similar to the symptoms of meniere's disease and malfunction of autonomic nervous system in western medicine. 4. Blood deficiency tinnitus in Miraculous Pivot $\ll$靈樞$\gg$ Sa Gi Jang Bu Byeong Hyeong <邪氣藏府病形> was similar to the symptoms of anemia in western medicine. 5. Tinnitus in Miraculous Pivot $\ll$靈樞$\gg$ Gyeong Geun <經筋> was similar to the myofacial pain syndrome of the sternocleidomastoid muscle and the masseter muscle in western medicine. 6. Gallbladder deficiency tinnitus in Miraculous Pivot $\ll$靈樞$\gg$ Gwol Hyeong <厥病> was similar to the symptoms of otitis media and labyrinthitis in western medicine. 7. Kidney deficiency tinnitus in Miraculous Pivot $\ll$靈樞$\gg$ Gyeol Gi <決氣> and Hai Ron <海論> was similar to the symptoms of degenerative auditory organ in western medicine. 8. Tinnitus in Internal Classic $\ll$內經$\gg$ showed close relations with the symptoms of the wind character. Conclusion : We analyzed the original text paragraphs of Internal Classic $\ll$內經$\gg$ and explanations about tinnitus. Further studies are needed to compare oriental medicine and western medicine diagnoses to develop better treatments for tinnitus.

• Journal of The Korean Association For Science Education
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• v.26 no.3
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• pp.356-366
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• 2006

The purpose of this study was to investigate the effects of offering similar experiences for hypothesis-generation based on abduction. Two hundred and seventy eight students in Seoul(8th and 10th grades) were requested to propose causal questions and generate hypotheses after observing an unfamiliar situation. Then, after having been presented numerous similar experimental situations to initial situation, the students were asked to regenerate a hypothesis. When the $X^2$ analysis was done to determine differences in hypothesis generation before and after offering the similar experimental situations, a meaningful difference appeared(p<.001). This study proposes that offering similar experimental situations ease hypothesis-generation based on abductive reasoning. Additionally, the second meaningful difference was discovered when the $X^2$ analysis was carried out to find differences in causal question proposal and hypothesis generation among students who had varied cognitive levels(p<.05) Considering the findings of the study, a progressive stage offering similar scenarios may further abductive reasoning while implementing lessons related to hypothesis generation in middle and high school.

• Journal of Haehwa Medicine
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• v.16 no.1
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• pp.115-126
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• 2007

Objectives : The purpose of this study is to find out relationship between Trigger points and Acupoints. Methods : We have researched some of oriental and western medical books about Trigger points and Acupoints from head to trunk. Conclusions : 1. In the head, there are 46 trigger points Among them, 19 trigger points correspond to Acupoints and 25 trigger points are similar to them 2. In the thorax, there are 33 trigger points Among them, 17 trigger points correspond to Acupoints and 20 trigger points are similar to them 3. In the upperimb, there are 20 trigger points Among them, 9 trigger points correspond to Acupoints and 13 trigger points are similar to them. 4 In the trunk, there are 11 trigger points. Among them, 5 trigger points correspond to Acupoints and 11 trigger points are similar to them.

• Journal of Periodontal and Implant Science
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• v.39 no.3
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• pp.359-365
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• 2009

Purpose: The purpose of this study was to investigate the ability of Mineral trioxide aggregate(MTA) to support osteoclastic differentiation from fetal rat calvarial cell. Methods: In this study, response of IL-6, RANKL, and OPG in fetal rat calvarial cells stimulated with IL-$1{\beta}$ on MTA was evaluated by ELISA and RT-PCR. Results: The results were as follows; there was no significant difference between glass and MTA at 5days. In ELISA analysis, Glass group and MTA group showed similar IL-6 expression, Glass+IL-$1{\beta}$ group and MTA+IL-$1{\beta}$ group showed similar IL-6 expression. In RT-PCR analysis, Glass group and MTA group showed similar IL-6, RANKL, OPG mRNA expression, MTA+IL-$1{\beta}$ group and Glass+IL-$1{\beta}$ group showed 3 fold increase of IL-6 and RNAKL mRNA expression when compared with MTA group. All groups showed similar OPG mRNA expression. Conclusions: MTA does not suppress cell proliferation and increase the proinflammatory cytokine that induce osteoclastogenesis. Thus, MTA is biocompatible material that could be used in various clinical conditions.

• Bioinformatics and Biosystems
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• v.1 no.1
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• pp.46-50
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• 2006

According to the advancement of experimental techniques in molecular biology, genomic and protein sequence databases are increasing in size exponentially, and mean sequence lengths are also increasing. Because the sizes of these databases become larger, it is difficult to search similar sequences in biological databases with significant homologies to a query sequence. In this paper, we present the N-gram indexing method to retrieve similar sequences fast, precisely and comparably. This method regards a protein sequence as a text written in language of 20 amino acid codes, adapts N-gram tokens of fixed-length as its indexing scheme for sequence strings. After such tokens are indexed for all the sequences in the database, sequences can be searched with information retrieval algorithms. Using this new method, we have developed a protein sequence search system named as ProSeS (PROtein Sequence Search). ProSeS is a protein sequence analysis system which provides overall analysis results such as similar sequences with significant homologies, predicted subcellular locations of the query sequence, and major keywords extracted from annotations of similar sequences. We show experimentally that the N-gram indexing approach saves the retrieval time significantly, and that it is as accurate as current popular search tool BLAST.

• Toxicological Research
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• v.17
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• pp.105-108
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• 2001

Several marine toxins with macrolide structure have been found to act on actin. One of these toxins is mycalolide B isolated from the genus Mycale. This compound belongs to macrolide antibiotics and consists of tris-oxazole with strong cytotoxic activity ($IC_{50}$: 10-50 nM for growth of L1210 murine leukemia cells). This compound was found to be an actin-depolymerizing agent with the mode of action distinct from that of the known actin inhibitor, cytochalasin D. Tolytoxin, a macrolide isolated from cyano-bacteria with similar chemical structure to mycalolide B, seems to have similar effect. Another macrolide compound, aplyronine A, showed the effects similar to those of mycalolide B. Although bistheonellide A, a dimeric macrolide, did not show a severing effect, it de polymerized F-actin and sequestered G-actin by forming 1 : 2 complex with G-actins. Swinholide A has a structure and effects similar to those of bistheonel-lide A. In conclusion, mycalolide B, tolytoxin, aplyronine A, bistheonellide A and swinholide A are the members of "actin de polymerizing macrolide" the mechanism of which is different from that of cytochalasin D.halasin D.

• Journal of Korean Institute of Industrial Engineers
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• v.41 no.2
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• pp.150-161
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• 2015

This paper proposes a new approach to technology valuation, the market-replacement cost approach which integrates the cost-based approach and market-based approach. The proposed approach estimates the market-replacement cost of a target technology using R&D costs of similar R&D projects previously conducted. Similar R&D projects are extracted from project database based on document similarity between project proposals and technology description of the target technology. R&D costs of similar R&D projects are adjusted by mirroring the rate of technological obsolescence and inflation. Market-replacement cost of the technology is then derived by calculating the weighted average of adjusted costs and similarity values of similar R&D projects. A case of "Prevention method and system for the diffusion of mobile malicious code" is presented to illustrate the proposed approach.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.3
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• pp.537-542
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• 2015

SNOMED CT, which is a standard clinical terminology, imposes an ambiguity problem of terminology selections caused by its huge expressive power and structural complexity. It is very difficult to distinguish similar terms and to select an appropriate term among them within short consultation hours. This paper analyzes the ambiguity problem and proposes a novel scheme for comparative search of similar terms. The proposed scheme provides a differential view of similar terms by defining a "is-not-a" relationship based on the hierarchical structure of the concepts. The result of this work improves the utilization of SNOMED CT such that medical officers can efficiently select an appropriate term among similar terms which represents patient's status adequately.

• The Journal of the Korea Contents Association
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• v.14 no.3
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• pp.40-51
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• 2014

Owing to importance of document copyright the need to detect document duplication and plagiarism is increasing. Many studies have sought to meet such need, but there are difficulties in document duplication detection due to technological limitations with the processing of natural language. This thesis designs and implements a discriminator of similar documents with natural language processing technique. This system discriminates similar documents using morphological analysis, syntactic analysis, and weight on low frequency and idiom. To evaluate the system, we analyze the correlation between human discrimination and term-based discrimination, and between human discrimination and proposed discrimination. This analysis shows that the proposed discrimination needs improving. Future research should work to define the document type and improve the processing technique appropriate for each type.

• International Journal of Fluid Machinery and Systems
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• v.5 no.1
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• pp.38-48
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• 2012

One centrifugal compressor is applied for refrigeration and its working substance is R134a. The operating points obtained by using similar conversion at different rotation speeds are compared with the numerical results. They keep consistent with each other while the rotation speeds are lower, but the error between them will become large with the increasing of the rotation speed. Then the operating points are obtained when the working substance is air by using two similar conversion methods separately. Based on the comparison, it can be obtained that the result of keeping the specific volume ratio of inlet and outlet is more accurate than the result of maintaining Ma number. Then the test result is compared with the similarity result and the numerical result when the working substance is air. It is obtained that the similarity result is more consistent with the test result better than the numerical result and the trend of efficiency and pressure ratio change with the flow rate is consistent with the test result. In the process of similar conversion, the efficiency ${\eta}$ is no useful for similitude design and it has less influence on the conversion result.