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The Study on Acute and Subacute Toxicity and Anti-Cancer Effects of cultivated wild ginseng Herbal acupuncture (정맥주입용(靜脈注入用) 산양산삼(山養山蔘) 증류약침(蒸溜藥鍼)의 급성(急性).아급성(亞急性) 독성실험(毒性實驗) 및 Sarcoma-180 항암효과(抗癌效果)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Kwon, Ki-Rok;Cho, A-La;Lee, Sun-Gu
    • Journal of Pharmacopuncture
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    • v.6 no.2
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    • pp.7-27
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    • 2003
  • Objective : The purpose of this study was to investigate acute and subacute toxicity and sarcoma-180 anti-cancer effects of herbal acupuncture with cultivated wild ginseng (distilled) in mice and rats. Method : Balb/c mice were injected intravenous with cultivated wild ginseng herbal acupuncture for $LD_{50}$ and acute toxicity test. Sprague-Dawley rats were injected intravenous with cultivated wild ginseng herbal acupuncture for subacute toxicity test. The cultivated wild ginseng herbal-acupuncture was injected at the tail vein of mice. Results : 1. In acute $LD_{50}$ toxicity test, there was no mortality thus unable to attain the value. 2. Examining the toxic response in the acute toxicity test, there was no sign of toxication. 3. In acute toxic test, running biochemical serum test couldn't yield any differences between the control and experiment groups. 4. In subacute toxicity test, there was no sign of toxication in the experimental groups and didn't show any changes in weight compared to the normal group. 5. In subacute toxicity test, biochemical serum test showed significant increase of Total albumin, Albumin, and Glucose in the experimental group I compared with the control group. Significant decrease of GOT, ALP, GPT, and Triglyceride were shown. In experiment group II, only Glucose showed significant increase compared with the control group. 6. Measuring survival rate for anti-cancer effects of Sarcoma-180 cancer cell line, all the experimental groups showed significant increase in survival rate. 7. Measuring NK cell activity rate, no significant difference was shown throughout the groups. 8. Measuring Interleukin-2 productivity rate, all the experimental groups didn't show significant difference. 9. For manifestation of cytokine mRNA, significant decrease of interleukin-10 was witnessed in the experimental group compared to the control group. Conclusion : According to the results, we can conclude cultivated wild ginseng herbal acupuncture caused negligible toxicity, and had anti-tumor effects in mice.

The Effects of the Total Patterns of Proprioceptive Neuromuscular Facilitation on Balance Improvement in Patients with Low back pain (고유수용성 신경근 촉진법 통합패턴이 요통환자의 균형에 미치는 영향)

  • Jung, Young-Jo;Bae, Sung-Soo
    • PNF and Movement
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    • v.5 no.2
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    • pp.73-88
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    • 2007
  • Purpose : The purpose of this study was to find out The effect of Low back pain on the total pattens of Proprioceptive neuromuscular facilitation(PNF). Methods : The subjects of the study were 62 low back pain patients. They were divided into two groups: 31 in the experimental group and 31 in the control group. the experimental group performed modalities and PNF total patterns three times for a week. the control group performed only modalities and ROM exercise three times for a week. Back muscle strength was measured by a back muscle strength measuring machine, the intensity of pain was measured by the Visual Analogue Scale (VAS), and the level of disability was measured by Oswestry low back pain disability index. Study measurements were compared before and after 6 weeks exercise program. The two groups of subjects were assessed by utilizing two different balance measurement: Static standing balance was measured by balance performance monitor (BPM) and Dynamic standing balance was measured by one leg standing(OLS). The scale for static standing balance was measured by using, sway area, sway path, max velocity. Results : The results of this study were as follow: 1) The score on visual analogue scale shows statistically significant increase on PNF group of post test(p<.05). 2) The score on Oswestry low back pain disability index. shows statistically significant decrease on PNF group of post test(p<.05). 3) The change sway area was statistically significant on pre-test and post-test(p<.05). 4) The change sway path was statistically significant on pre-test and post-test(p<.05). 5) The change max velocity was statistically significant on pre-test and post-test(p<.05). 6) The score on one leg standing shows statistically significant increase on PNF group of post test(p<.05). Conclusion : These results of this study indicated that Proprioceptive Neuromuscular Facilitation Total patterns which performed for six weeks had a statistically significant influence on low back pain. If the exercise for muscle strength is performed along with therapeutic stabilizing exercise, a better effect can be expected on low back pain. We hope that this study will provide a basic data for further research with a bigger group and on a long-term effect.

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Acute effect of self-myofascial release using a foam roller on the plantar fascia on hamstring and lumbar spine superficial back line flexibility

  • Do, Kwangsun;Kim, Jaeeun;Yim, Jongeun
    • Physical Therapy Rehabilitation Science
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    • v.7 no.1
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    • pp.35-40
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    • 2018
  • Objective: The purpose of this study was to investigate the immediate effect of applying self-myofascial release (SMR) to the plantar fascia using a foam roller on hamstring and lumbar spine superficial back line (SBL). Design: Randomized controlled trial. Methods: Thirty-one healthy adults agreed to the method and purpose of the study. Selection and exclusion criteria were screened, and baseline measurements for the Toe Touch test and passive straight leg raise (PSLR) test were obtained. The participants were then randomly assigned to the SMR group or the sham group. After group assignment, the SMR group rolled the surface of the foot from the heel to the metatarsal head using a foam roller for 5 minutes. The sham group received passive mobilization of the ankle joint in the supine position. Afterwards, the Toe Touch test and the passive straight leg-raise test were re-assessed. Results: In the SMR group, the Toe Touch test results showed significant improvement (p<0.05). Left and right PSLR test results showed a significant increase (p<0.05). In the sham group, there was no significant difference between pre and post-test results. The SMR group showed a significant difference in the PSLR test and Toe Touch test compared to the sham group (p<0.05). Conclusions: The results of this study showed that SMR on the plantar fascia was immediately effective for improving the flexibility of the SBL of the lumbar spine and hamstring.

The Effect of Therapeutic Ultrasound and Static Stretching of the Hamstring Muscle on Flexibility and Static Balance Ability (초음파 치료와 정적 스트레칭이 뒤넙다리근의 유연성과 정적균형에 미치는 영향)

  • Cho, Seung-bong;Park, Mi-young;Won, Ji-sun;Kim, Ye-lin;Hong, Joon-taek;Kim, Seong-ho
    • Journal of Korean Physical Therapy Science
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    • v.26 no.1
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    • pp.45-53
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    • 2019
  • Background: The purpose of present study was to examine the effect of ultrasound therapy and static stretching on hamstring length and balance. Design: Randomized Controlled Trial. Methods: A total of 30 adults in S college, Seongnam city, Gyeonggi-do, between the ages of 20-30 were randomly assigned to two groups. Group 1 (n=15) had ultrasound therapy, called US group. Group 2 (n=15) had static stretching, called SS group. Measurements were taken prior to starting the program and after completing the experiment using Finger to floor test and Active knee extension test to get the results of hamstring flexibility and the ability of static balance. Paired t-test was used to compare each group pre-test values to post-test values and to compare US post-test values to SS post-test values on PASW 18.0. Results: 1) Both hamstring SS group and US group had significant increase (p<.05) in Finger to floor test and Active knee extension test. 2) Dominant leg standing had significant change (p<.05) only in US group. 3) There was no significant difference between US group and SS group. Conclusion: Results showed that US group and SS group had an effect on changes in hamstring length (p<.05). However, they did not show a significant increase in static balance. Further effective studies on hamstring SS group and US group were needed based on this examination.

Effects of an odor or taste stimulus applied to an artificial teat on the suckling behavior of newborn dairy calves

  • Malidaki, Maria;Laska, Matthias
    • Journal of Animal Science and Technology
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    • v.60 no.4
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    • pp.16.1-16.11
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    • 2018
  • Background: In their first days of life, dairy calves in artificial rearing systems often have difficulty using an artificial teat for feeding. Methods: We examined the age at which calves are able to stand up voluntarily and suckle as well as their suckling behavior when presented with a plain dry teat versus a dry teat modified with a presumably attractive odor or taste substance. Single-housed newborn dairy calves (n = 51) were presented for ten consecutive days with a two-minute two-choice test, in which suckling time was recorded for 1) a plain (control) teat versus a glucose-coated teat (taste test) and 2) a plain teat versus a teat with a "Freshly Cut Grass" odor (odor test). Results: On average, the calves were able to stand up voluntarily and suckle from the second or third day of age on. The "Freshly Cut Grass" odor had no significant effect on their suckling behavior. In contrast, the calves showed a significant preference for suckling the glucose-coated teat and displayed a significantly longer total suckling time in the taste test compared to the odor test. There were no significant differences between sexes regarding suckling behavior. Conclusion: The results of the present study show that glucose had a significant effect on the calves' teat preference and significantly increased total suckling time with a dry artificial teat. As such, glucose may increase suckling motivation in non-efficient drinkers or ill calves with low motivation to suckle.

The change of the Pre-Post a maximal exercise on the Physiological Variable in the athletics children runners (소년체전 육상선수들의 최대 운동부하 전.후 혈중 생리적 변인 변화에 관한 연구)

  • Koo, Sung-Wan;Park, Han-Su
    • Journal of Korean Physical Therapy Science
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    • v.11 no.1
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    • pp.5-13
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    • 2004
  • The purpose of this study was to the Pre-Post maximal exercise for analyze the Physiological Variable(Lactate, LDH, Glucose) in the runners. The subjects were 12 volunteers 6 sprinters and 6 distance runners who agreed to intention of this study. Subjects performed until possible all-out trials. Blood samples were taken from a median cubital vein Pre-Post exercise and every rest 5min during the all-out trial. The results obtained were summarized as follow ; 1) Lactate of Pre-Post exercise in treadmill test showed no significant difference between sprinters and distance runners, but showed significant in sprinters and distance respectively 2) LDH of Pre-Post exercise in treadmill test showed no significant difference between sprinters and distance runners, and that showed no significant in sprinters and distance respectively 3) Glucose of Pre-Post exercise in treadmill test showed no significant difference between sprinters and distance runners, and showed no significant in distance, but showed significant in sprinters therefor, since the runners has an intermittent characteristic which includes a frequent momentary change, it needs the fitness training that being consisted of various training, in the training method, it needs the training process which is from the whole fitness to specific fitness to improve general physical ability.

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Nutrition knowledge and attitude analysis of elderly people for the development of nutrition education program (노년층의 영양교육 프로그램 개발을 위한 기초조사 : 영양지식 및 태도)

  • Lee, Jin-Mi;Yang, Il-Seon;Chae, In-Suk
    • Journal of the Korean Dietetic Association
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    • v.4 no.1
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    • pp.76-87
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    • 1998
  • The purpose of this study was to examine the nutrition knowledge and attitude of the elderly for developing nutrition education program. The nutrition knowledge test was consisted of nutrition, nutrients, weight control, food safety, and shopping tips by developing the table of specifications. The nutrition attitude test was comprised of seventeen questions for invention, self-efficacy, control, and outcome expectation. A total of 140 elderly living at home responded to both nutrition knowledge and attitude test. According to the results of nutrition knowledge test, the mean was 13.3 at the maximum 18 points and 51.4% respondents got more than 14 points. Significant differences were found with age (p<0.05, $x^2$=21.46), charge of income (p<0.05, $x^2$=8.86) and monthly expenses(p<0.05, $x^2$=22.95). The results of nutrition attitude test showed that the mean value of 40.89 points at the maximum 51 points and 58.6% of respondents rated more than 40.89 points. In exploring the relationship between the demographic variables(sex, age, educational level, and monthly expenses) and for attitude concepts, a significant correlation was found. Correlation among the knowledge for nutrition, nutrients, and the attitudes for nutrition was significant(p<0.05).

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The Effect of Singing Intervention for Women Elderly with Dysphagia Risk (연하장애 위험 여성노인의 노래중재 적용 효과)

  • Yun, Ok-Jong;Lee, Young-Hee
    • Korean Journal of Adult Nursing
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    • v.24 no.4
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    • pp.380-389
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    • 2012
  • Purpose: This study was conducted to describe the risk of dysphagia and to evaluate the effects of a singing intervention for women elderly in community. Methods: One-group pre test-post test design was used. The subjects were 29 women over the age of sixty and residing in a local area. A singing intervention consisted of breathing, vowel production and singing. The one hour intervention occurred once a week for eight weeks. The variables of dysphagia risk, a swallowing test, and nutritional status were measured. Analysis was done by paired t-test. Results: There was a significant decrease in the score of dysphagia risk (p<.001). There were significant increases in the swallowing test scores [modified water swallowing test (p=.032), food test (p=.001)]. There were no significant differences in nutritional status (triceps skin fold thickness, mid arm muscle circumference). Conclusion: The findings support that a singing intervention can be helpful in reducing the risk of dysphagia may improve deglutition for the women elderly. These results suggest that this study may contribute to the use of a singing intervention for women elders with dysphagia risk.

A Study of Dichotic Listening Using the TOEIC Listening Test

  • Lee, Myung-Sook;Cha, Kyung-Whan
    • Speech Sciences
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    • v.13 no.2
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    • pp.121-132
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    • 2006
  • The purpose of this research was to investigate dichotic listening, that is, whether the left and right ears have different functionalities in actual listening. Unlike previous studies, which used short words or a list of two or three numbers, these researchers investigated more comprehensive listening ability using the Toeic listening test. Sixty-three university students participated in this study. The subjects took three tests in total: one using only the right ear, another using the left ear, and the third using both. T-analysis of SPSS on the data revealed that there is a significant difference between the test results with only the right or left ear and the ones with both ears. So we cannot find right-ear priority in this study. We can see that in comprehensive listening, right hemisphere plays an important role as well as left hemisphere. When grouped according to language ability, test result of low group is the same as the total test result. However, in high group there is no significant difference between the test results with left ear and the results with both ears in high group. In mid group there is no significant difference between the test results with right ear and the results with both ears. The different functionalities of left and right ears and suggestions for future research are presented.

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Comparison of Effects of Nursing Process Reeducation according to Academic Credit Bank System Student Nurses' Clinical Experience - Expertise, Critical Thinking Disposition, Clinical Decision Making - (학점은행제 교육과정 간호사들의 임상경력에 따른 간호과정 재교육의 효과 비교 - 숙련성, 비판적사고 성향, 임상의사결정 능력을 중심으로 -)

  • Yi, Yeo-Jin
    • Journal of Korean Academy of Nursing Administration
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    • v.15 no.2
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    • pp.275-283
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    • 2009
  • Purpose: This study investigated the effects of reeducation of nursing process on nurses' expertise, critical thinking disposition, and clinical decision making. Methods: Data were collected from March to June, 2007. The subjects were 47 Academic Credit Bank System Student Nurses. They were taught 'nursing process' during 1 semester(15weeks). 47 nurses were divided into three groups according to clinical experience(under 3 years, 3 to under 5 years, 5 years or more). After 15 weeks, the effects of education were compared using a paired t-test between pre-test and post-test. Results: There was a significant difference in the 3 to under 5 years experienced nurses's expertise(t=-3.659, p=.004) between the pre-test and post-test. There was a significant difference in the 5 years or more experienced nurses's expertise(t=-5.781, p<.001) and critical thinking disposition(t=-3.345, p=.003) between the pre-test and post-test. There were no significant differences in clinical decision making(accuracy, proficiency, and confidence) of 3 groups. Conclusion: Reeducation of nursing process is a valuable teaching and an evaluation strategy for 5 years or more experienced nurses to improve expertise and critical thinking disposition. We need to develop continuing education program for improving nurses' clinical decision making.

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