• Journal of the Society of Naval Architects of Korea
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• v.61 no.1
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• pp.1-7
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• 2024

Underwater sound speed is an important analysis parameter on an estimation of the underwater radiated noise (URN) emitted from vessels. This paper aims to present an underwater sound speed measurement procedure using a cross-correlation of time-domain acoustic signals and validate the procedure through an experiment in a reverberant water tank. For the purpose, time-domain acoustic signals transmitted by a Gaussian pulse excitation from an acoustic projector have been measured at 20 hydrophone positions in the reverberant water tank. Then, the sound speed in water has been calculated by a linear regression using 190 cross-correlation cases of distances and time lags between the received signals and the result has been compared with those estimated by the existing empirical formulae. From the result, it is regarded that the presented experimental procedure to measure an underwater sound speed is reliably applicable if the time resolution is sufficiently high in the measurement.

• Journal of Advanced Navigation Technology
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• v.19 no.1
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• pp.15-21
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• 2015

WA-DGNSS is a system to service for users using a satellite which received correction data from ground station that calculates the relative errors of the tracked GNSS signals and sends to a satellite. Users are guaranteed the reliability of the GNSS signal and the accuracy of positioning. ICAO recommends the application of WA-DGNSS for the airplane taking off and landing process. In this paper, we suggests methods to verify of the pre-developed WA-DGNSS reference software constituting modules and an integration test process refer to the RTCA DO-278 which is a document for the development process of an aeronautics software. Also, we statistically verified the reference software test through our methods. And then, we confirmed to performance the function of the reference software properly.

• Korean Journal of Agricultural Science
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• v.46 no.1
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• pp.183-194
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• 2019

Adulteration of argan oil with some other cheaper oils with similar chemical compositions has resulted in increasing demands for authenticity assurance and quality control. Fast and simple analytical techniques are thus needed for authenticity analysis of high-priced argan oil. Raman spectroscopy is a potent technique and has been extensively used for quality control and safety determination for food products In this study, Raman spectroscopy in combination with a net analyte signal (NAS)-based methodology, i.e., hybrid linear analysis method developed by Goicoechea and Olivieri in 1999 (HLA/GO), was used to predict the different concentrations of olive oil (0 - 20%) added to argan oil. Raman spectra of 90 samples were collected in a spectral range of $400-400cm^{-1}$, and calibration and validation sets were designed to evaluate the performance of the multivariate method. The results revealed a high coefficient of determination ($R^2$) value of 0.98 and a low root-mean-square error (RMSE) value of 0.41% for the calibration set, and an $R^2$ of 0.97 and RMSE of 0.36% for the validation set. Additionally, the figures of merit such as sensitivity, selectivity, limit of detection, and limit of quantification were used for further validation. The high $R^2$ and low RMSE values validate the detection ability and accuracy of the developed method and demonstrate its potential for quantitative determination of oil adulteration.

• The Korean Journal of Applied Statistics
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• v.19 no.2
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• pp.319-330
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• 2006

A signal in real world usually composes of multiple signals having different scales of frequencies. For example sun-spot data is fluctuated over 11 year and 85 year. Economic data is supposed to be compound of seasonal component, cyclic component and long-term trend. Decomposition of the signal is one of the main topics in time series analysis. However when the signal is subject to nonstationarity, traditional time series analysis such as spectral analysis is not suitable. Huang et. at(1998) proposed data-adaptive method called empirical mode decomposition (EMD) . Due to its robustness to nonstationarity, EMD has been applied to various fields. Huang et. at, however, have not considered denoising when data is contaminated by error. In this paper we propose efficient denoising method utilizing cross-validation.

• International Journal of Highway Engineering
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• v.20 no.3
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• pp.85-92
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• 2018

PURPOSES : In this study, analyze the characteristics of IOC indicator 'threshold' which is needed when evaluating the traffic signal operation status with ESPRESSO in various grade road traffic environment of Seoul metropolitan city and derive suggested value to use in field practice. METHODS : Using the computerized database program (Postgresql), we extracted data with regional characteristics (Arterial, Collector road) and temporal characteristics (peak hour, non-peak hour). Analysis of variance and Duncan's validation were performed using statistical analysis program (SPSS) to confirm whether the extracted data contains statistical significance. RESULTS : The analysis period of the main and secondary arterial roads was confirmed to be suitable from 14 days to 60 days. For the arterial, it is suggested to use 20 km/h as the critical speed for PM peak hour and weekly non peak hour. It is suggested to use 25 km/h as the critical speed for AM peak hour and night non peak hour. As for the collector road, it is suggested to use 20 km/h as the critical speed for PM peak hour and weekly non peak hour. It is suggested to use 30 km/h as the critical speed for AM peak hour and night non peak hour. CONCLUSIONS : It is meaningful from a methodological point of view that it is possible to make a reasonable comparative analysis on the signal intersection pre-post analysis when the signal operation DB is renewed by breaking the existing traffic signal operation evaluation method.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7421-7426
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• 2013

Background: Colorectal cancer is the fourth most common cancer worldwide and the second leading cause of cancer-related death. FOLFOX is the most common regimen used in the first-line chemotherapy in advanced colorectal cancer, but only half of the patients respond to this regimen and we have almost no clue in predicting resistance in such first-line application. Methods: To explore the potential molecular biomarkers predicting the resistance of FOLFOX regimen as the first-line treatment in advanced colorectal cancer, we screened microRNAs in serum samples from drug-responsive and drug-resistant patients by microarrays. Then differential microRNA expression was further validated in an independent population by reverse transcription and quantitative real-time PCR. Results: 62 microRNAs expressing differentially with fold-change >2 were screened out by microarray analysis. Among them, 5 (miR-221, miR-222, miR-122, miR-19a, miR-144) were chosen for further validation in an independent population (N=72). Our results indicated serum miR-19a to be significantly up-regulated in resistance-phase serum (p=0.009). The ROC curve analysis showed that the sensitivity of serum miR-19a to discriminate the resistant patients from the response ones was 66.7%, and the specificity was 63.9% when the AUC was 0.679. We additionally observed serum miR-19a had a complementary value for cancer embryonic antigen (CEA). Stratified analysis further revealed that serum miR-19a predicted both intrinsic and acquired drug resistance. Conclusions: Our findings confirmed aberrant expression of serum miR-19a in FOLFOX chemotherapy resistance patients, suggesting serum miR-19a could be a potential molecular biomarker for predicting and monitoring resistance to first-line FOLFOX chemotherapy regimens in advanced colorectal cancer patients.

• Journal of Biomedical Engineering Research
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• v.41 no.5
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• pp.185-194
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• 2020

Arrhythmia is basically diagnosed with the electrocardiogram (ECG) signal, however, ECG is difficult to measure and it requires expert help in analyzing the signal. On the other hand, the radial pulse can be measured with easy and uncomplicated way in daily life, and could be suitable bio-signal for the recent untact paradigm and extensible signal for diagnosis of Korean medicine based on pulse pattern. In this study, we developed an irregular radial pulse detection algorithm based on a learning model and considered its applicability as arrhythmia screening. A total of 1432 pulse waves including irregular pulse data were used in the experiment. Three data sets were prepared with minimal preprocessing to avoid the heuristic feature extraction. As classification algorithms, elastic net logistic regression, random forest, and extreme gradient boosting were applied to each data set and the irregular pulse detection performances were estimated using area under the receiver operating characteristic curve based on a 10-fold cross-validation. The extreme gradient boosting method showed the superior performance than others and found that the classification accuracy reached 99.7%. The results confirmed that the proposed algorithm could be used for arrhythmia screening. To make a fusion technology integrating western and Korean medicine, arrhythmia subtype classification from the perspective of Korean medicine will be needed for future research.

• Radiation Oncology Journal
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• v.34 no.1
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• pp.64-75
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• 2016

Purpose: In order to evaluate the relationship between the dose to the liver parenchyma and focal liver reaction (FLR) after stereotactic ablative body radiotherapy (SABR), we suggest a novel method using a three-dimensional dose distribution and change in signal intensity of gadoxetate disodium-gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) hepatobiliary phase images. Materials and Methods: In our method, change of the signal intensity between the pretreatment and follow-up hepatobiliary phase images of Gd-EOB-DTPA-enhanced MRI was calculated and then threshold dose (TD) for developing FLR was obtained from correlation of dose with the change of the signal intensity. For validation of the method, TDs for six patients, who had been treated for liver cancer with SABR with 45-60 Gy in 3 fractions, were calculated using the method, and we evaluated concordance between volume enclosed by isodose of TD by the method and volume identified as FLR by a physician. Results: The dose to normal liver was correlated with change in signal intensity between pretreatment and follow-up MRI with a median $R^2$ of 0.935 (range, 0.748 to 0.985). The median TD by the method was 23.5 Gy (range, 18.3 to 39.4 Gy). The median value of concordance was 84.5% (range, 44.7% to 95.9%). Conclusion: Our method is capable of providing a quantitative evaluation of the relationship between dose and intensity changes on follow-up MRI, as well as determining individual TD for developing FLR. We expect our method to provide better information about the individual relationship between dose and FLR in radiotherapy for liver cancer.

• Journal of the Institute of Convergence Signal Processing
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• v.23 no.2
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• pp.62-69
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• 2022

An electrocardiogram (ECG) is one of the most important biosignals, and in particular, continuous ECG monitoring is very important in patients with arrhythmia. There are many different types of arrhythmia (sinus node, sinus tachycardia, atrial premature beat (APB), and ventricular fibrillation) depending on the cause, and continuous ECG monitoring during daily life is very important for early diagnosis of arrhythmias and setting treatment directions. The ECG signal of arrhythmia patients is very unstable, and it is difficult to detect the R-peak point, which is a key feature for automatic arrhythmias detection. In this study, we develped a continuous measuring Holter ECG monitoring device and software for analysis and confirmed the utility of R-peak of the ECG signal with MIT-BIH arrhythmia database. In future studies, it needs the validation of algorithms and clinical data for morphological classification and prediction of arrhythmias due to various etiologies.

• Smart Structures and Systems
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• v.11 no.5
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• pp.477-496
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• 2013

Due to their cost-effectiveness and ease of installation, wireless smart sensors (WSS) have received considerable recent attention for structural health monitoring of civil infrastructure. Though various wireless smart sensor networks (WSSN) have been successfully implemented for full-scale structural health monitoring (SHM) applications, monitoring of low-level ambient strain still remains a challenging problem for WSS due to A/D converter (ADC) resolution, inherent circuit noise, and the need for automatic operation. In this paper, the design and validation of high-precision strain sensor board for the Imote2 WSS platform and its application to SHM of a cable-stayed bridge are presented. By accurate and automated balancing of the Wheatstone bridge, signal amplification of up to 2507-times can be obtained, while keeping signal mean close to the center of the ADC span, which allows utilization of the full span of the ADC. For better applicability to SHM for real-world structures, temperature compensation and shunt calibration are also implemented. Moreover, the sensor board has been designed to accommodate a friction-type magnet strain sensor, in addition to traditional foil-type strain gages, facilitating fast and easy deployment. The wireless strain sensor board performance is verified through both laboratory-scale tests and deployment on a full-scale cable-stayed bridge.