• Proceedings of the KSRS Conference
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• 2008.10a
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• pp.220-223
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• 2008

A camera system for the satellite application performs the mission of observation by measuring radiated light energy from the target on the earth. As a development stage of the system, the signal level analysis by estimating the number of electron collected in a pixel of an applied CCD is a basic tool for the performance analysis like SNR as well as the data path design of focal plane electronic. In this paper, two methods are presented for the calculation of the number of electrons for signal level analysis. One method is a quantitative assessment based on the CCD characteristics and design parameters of optical module of the system itself in which optical module works for concentrating the light energy onto the focal plane where CCD is located to convert light energy into electrical signal. The other method compares the design\ parameters of the system such as quantum efficiency, focal length and the aperture size of the optics in comparison with existing camera system in orbit. By this way, relative count of electrons to the existing camera system is estimated. The number of electrons, as signal level of the camera system, calculated by described methods is used to design input circuits of AD converter for interfacing the image signal coming from the CCD module in the focal plane electronics. This number is also used for the analysis of the signal level of the CCD output which is critical parameter to design data path between CCD and A/D converter. The FPE(Focal Plane Electronics) designer should decide whether the dividing-circuit is necessary or not between them from the analysis. If it is necessary, the optimized dividing factor of the level should be implemented. This paper describes the analysis of the electron count of a camera system for a satellite application and then of the signal level for the interface design between CCD and A/D converter using two methods. One is a quantitative assessment based on the design parameters of the camera system, the other method compares the design parameters in comparison with those of the existing camera system in orbit for relative counting of the electrons and the signal level estimation. Chapter 2 describes the radiometry of the camera system of a satellite application to show equations for electron counting, Chapter 3 describes a camera system briefly to explain the data flow of imagery information from CCD and Chapter 4 explains the two methods for the analysis of the number of electrons and the signal level. Then conclusion is made in chapter 5.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.35C no.10
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• pp.1-11
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• 1998

This paper presents a new implementation method of the pulsed NMR(nuclear magnetic resonance) apparatus, which contains a single coil in a magnet console, to detect a NMR signal. Applying an RF magnetic field of 5MHz to the magnet console which is designed to have Larmor frequency of 5MHz for hydrogen atom, the hydrogen NMR signal was obtained from the glycerin which was put in the magnet console as a sample. The DC magnetic field in the magnet console was implemented with a permanent magnet of 1168 gauss and the RF magnetic field was generated appling an RF signal with the frequency of 5MHz and the current magnitude of 8A to a coil of 5.73${\mu}$H. The magnitude of the NMR signal was maximum when the RF magnetic field was generated for 2.8 ${\mu}$sec, and the period of generating the RF magnetic field was designed to 100msec for detecting the NMR signal repeatedly. The NMR signal, radiated from the sample in the magnetic console, was appeared as an amplitude-modulated signal with a frequency equal to the Larmor frequency. The signal, induced in the coil, was amplified in the tx/rx separation circuit, preamplifier and intermediate amplifier by a factor of 20.7dB, 36dB and 40dB, respectively, and the signal was detected by a synchronous detection circuits, then the NMR signal was obtained.

• Journal of dental hygiene science
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• v.19 no.4
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• pp.254-260
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• 2019

Background: The primary aims of periodontal disease treatment is to remove dental plaque and calculus, the main causes of tooth loss, and restore periodontal tissue destroyed by inflammation. Periodontal disease treatment should also help maintain the alveolar bone, alleviate inflammation, and promote periodontal ligament cell proliferation, which is essential for tissue regeneration. Conventional antibiotics and anti-inflammatories have adverse side effects, especially during long-term use, so there is a need for adjunct treatment agents derived from natural products. The purpose of this study was to investigate whether the herbal flavone baicalein has the osteogenic activity under inflammatory conditions, and assess the involvement of osteoblast immediate early response 3 (IER3) expression. Methods: Human osteoblastic MG-63 cells were cultured with the pro-inflammatory cytokines tumor necrosis factor α and interleukin 1β in the presence and absence of baicalein. Proliferation was assessed using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide assay, and expression of IER3 mRNA was assessed using real-time polymerase chain reaction. The expression of IER3 protein levels and activation of associated signal transduction pathways were assessed using western blotting. Results: Baicalein increased IER3 mRNA and protein expression synergistically. In addition, baicalein reversed the suppression of cell proliferation, and the downregulation of osteogenic transcription factor runt-related transcription factor 2 and osterix induced by pro-inflammatory cytokines. Baicalein also upregulated the phosphorylation of c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK 1/2). The upregulation of IER3 by pro-inflammatory cytokines was blocked by pretreatment with inhibitors of AKT, p38, JNK, and ERK 1/2. Conclusion: Baicalein mitigates the deleterious responses of osteoblasts to pro-inflammatory cytokines. Further, IER3 enhanced the effect of baicalein via activation of AKT, p38, JNK, and ERK pathways.

• Journal of the Institute of Electronics and Information Engineers
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• v.54 no.4
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• pp.108-112
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• 2017

High-intensity-discharge lamps are widely utilized in outdoor and indoor lighting circumstances that need high luminance. In lighting applications for MHD lamps, the size of the lamp ballast circuit is an important factor and should be as small as possible. The electronic ballast for MHD lamps is superior to the electromagnetic(EM) ballast in that it saves energy, and has smaller volume and lighter weight. In this paper, highly efficient cost-effective and small sized electronic ballast for Metal Halide Lamp with high power factor using Digital Signal Processor are proposed. The proposed electronic ballast for MHD lamps combines a boost PFC converter with a half-bridge inverter, the algorithms of the power factor correction and ballast control were implemented using the TI's TMS320LF2406 CPU. Experimental results validate the ballast is also useful and reasonably suggested.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.2
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• pp.251-256
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• 2001

An error probability analysis is performed far a hybrid DS/SFH spread-spectrum system using minimum shift keying(MSK) modulation. The channel is assumed to be a Rayleigh fading channel with partial-band noise interference. Expressions are derived for the bit error rate(BER) in the context of Rician and Rayleigh fading channels, as a function of the average signal-to-noise ratio(SNR) $E_b/N_0$, the average signal-to- interference ratio(SJR) $E_b/N_J$, and channel parameters. As a result, in the fading channel with large Rician factor, K, which denotes the ratio of power of the direct and the diffused components, the partial-band interference is the worst case. On the other hand, in Rayleigh fading channel(K=0), the full-band interference($\rho$=1) brings the system to the worst case. Performance comparisons among various channels show that the factor K has much large effect on overall performance. For example, in conditions of $\rho$=0.1 and BER=$10^-2$, the system in Rician channel with K=10 requires more 1.9 dB SNR than that in AWGN channel, whereas it is less 5 dB SNR than that in the Rayleigh channel with K=0.

• Nutrition Research and Practice
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• v.8 no.5
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• pp.521-525
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• 2014

BACKGROUND/OBJECTIVES: Artemisinin (AT), an active compound in Arternisia annua, is well known as an anti-malaria drug. It is also known to have several effects including anti-oxidant, anti-inflammation, and anti-cancer activities. To date, the effect of AT on vascular disorders has not been studied. In this study, we investigated the effects of AT on the migration and proliferation of vascular smooth muscle cells (VSMC) stimulated by platelet-derived growth factor BB (PDGF-BB). MATERIALS/METHODS: Aortic smooth muscle cells were isolated from Sprague-Dawley rats. PDGF-BB stimulated VSMC migration was measured by the scratch wound healing assay and the Boyden chamber assay. Cell viability was determined by using an EZ-Cytox Cell Viability Assay Kit. The production of reactive oxygen species (ROS) in PDGF-BB stimulated VSMC was measured through $H_2DCF$-DA staining. We also determined the expression levels of signal proteins relevant to ROS, including measures of extracellular signal-regulated kinase (ERK) 1/2 measured by western blot analysis and matrix metalloproteinase (MMP) 9 measured by reverse transcription-polymerase chain reaction (RT-PCR). RESULTS: AT ($10{\mu}M$ and $30{\mu}M$) significantly reduced the proliferation and migration of PDGF-BB stimulated VSMC in a dose-dependent manner. The production of ROS, normally induced by PDGF-BB, is reduced by treatment with AT at both concentrations. PDGF-BB stimulated VSMC treated with AT ($10{\mu}M$ and $30{\mu}M$) have reduced phosphorylation of ERK1/2 and inhibited MMP9 expression compared to untreated PDGF-BB stimulated VSMC. CONCLUSIONS: We suggest, based on these results, that AT may exert an anti-atherosclerotic effect on PDGF-BB stimulated VSMCs by inhibiting their proliferation and migration through down-regulation of ERK1/2 and MMP9 phosphorylation.

• Biomedical Science Letters
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• v.12 no.3
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• pp.249-254
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• 2006

It has been reported that liver is a very important organ to xenotransplantation. Pig is known to be a most suitable species in transplantation of human organs. However, the physiological function of pig hepatocytes is not clear elucidated. Epidermal growth factor (EGF) is known to be a mitogen in various cell systems. Thus, we examined the effect of EGF on cell proliferation and its related signal cascades in primary cultured pig hepatocytes. EGF stimulates cell proliferation in a dose (>1ng/ml) dependent manner. EGF-induced increase of $[^3H]-thymidine$ incorporation was blocked by AG 1478 ($10^{-6}M$, an EGF receptor antagonist) genistein and herbymycin A (tyrosine kinase inhibitors, $10^{-6}M$), suggesting the role of activation and tyrosine phosphorylation of EGF receptor. In addition, EGF-induced increase of $[^3H]-thymidine$ incorporation was prevented by neomycin $(10^{-4}M)$, U73122 $(10^{-5}M)$ (phospholipase C [PLC] inhibitors), staurosporine ($(10^{-8}M)$, or bisindolylmaleimide I $(10^{-6}M)$ (protein kinase C [PKC] inhibitors), suggesting the role of PLC and PKC. Moreover, EGF-induced increase of $[^3H]-thymidine$ incorporation was blocked by PD 98059 (a p44/42 mitogen activated protein kinase [MAPK] inhibitor), SB 203580 (a p38 MAPK inhibitor), and SP 600125 (a JNK inhibitor). EGF increased the translocation of PKC from cytosol to membrane fraction and activated p42/44 MAPK, p38 MAPK and JNK. In conclusion, EGF stimulates cell proliferation via PKC and MAPK in cultured pig hepatocytes.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.15 no.3 s.96
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• pp.320-328
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• 2005

Last target of architectural acoustics is that people wish to convey voice effectively from the space adaptively in use purpose in building. But, how exactly through space sound (sound source) that wish to deliver from indoor can be passed method to do quantification and evaluate quantity of sound by method to serve indoor architectural acoustics estimation summer period and methods to estimate definition propose. This Study searches special quality of sound source about MLS signal that is occurred short-answer sound source (pistol sound source) and nondirectional speaker among indoor sound estimation method, and measure and analyzed reverberation time (RT60), definition (C80, D50) by regulation of each ISO 3382 in age place (classroom, hall, gymnasium). Analysis result and sound factor among could know that d of two sound sources converges in measurement error extent about reverberation time (RT60) of analysis incidental and sound factors and value shows change irregularly about sound factor of D50, C80, pistol sound source judged there is problem. Also, could know that problem is happened in deflection except reverberation time is in deflection analysis with wave that measure each in fixed distance in branch. Finally, when differ size of sound source and measure about change of sound pressure level in case measure sound pressure level giving difference about 10 dB, sound factor could know that there is no different effect.

• The Plant Pathology Journal
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• v.29 no.4
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• pp.364-373
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• 2013

It has been known that most regulation of pathogenicity factor (rpf ) genes in xanthomonads regulates virulence in response to the diffusible signal factor, DSF. Although many rpf genes have been functionally characterized, the function of rpfE is still unknown. We cloned the rpfE gene from a Xanthomonas oryzae pv. oryzae (Xoo) Korean race KACC10859 and generated mutant strains to elucidate the role of RpfE with respect to the rpf system. Through experiments using the rpfE-deficient mutant strain, we found that mutation in rpfE gene in Xoo reduced virulence, swarm motility, and production of virulence factors such as cellulase and extracellular polysaccharide. Disease progress by the rpfE-deficient mutant strain was significantly slowed compared to disease progress by the wild type and the number of the rpfE-deficient mutant strain was lower than that of the wild type in the early phase of infection in the inoculated rice leaf. The rpfE mutant strain was unable to utilize sucrose or xylose as carbon sources efficiently in culture. The mutation in rpfE, however, did not affect DSF synthesis. Our results suggest that the rpfE gene regulates the virulence of Xoo under different nutrient conditions without change of DSF production.

• Journal of Institute of Control, Robotics and Systems
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• v.19 no.6
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• pp.527-533
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• 2013

BCI (Brain-Computer Interface) is a system that transforms a subject's brain signal related to their intention into a control signal by classifying EEG (electroencephalograph) signals obtained during the imagination of movement of a subject's limbs. The BCI system allows us to control machines such as robot arms or wheelchairs only by imaging limbs. With the exact same experiment environment, activated brain regions of each subjects are totally different. In that case, a simple approach is to use as many channels as possible when measuring brain signals. However the problem is that using many channels also causes other problems. When applying a CSP (Common Spatial Pattern), which is an EEG extraction method, many channels cause an overfitting problem, and in addition there is difficulty using this technique for medical analysis. To overcome these problems, we suggest an optimal channel selection method using a BPSO (Binary Particle Swarm Optimization), BPSO with channel impact factor, and GA. This paper examined optimal selected channels among all channels using three optimization methods and compared the classification accuracy and the number of selected channels between BPSO, BPSO with channel impact factor, and GA by SVM (Support Vector Machine). The result showed that BPSO with channel impact factor selected 2 fewer channels and even improved accuracy by 10.17~11.34% compared with BPSO and GA.