• Proceedings of the KSR Conference
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• 2009.05b
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• pp.483-488
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• 2009

When a train enters into the tunnel with high speed, a compression wave generated inside the tunnel has been studied as a one-dimensional phenomenon. However, one-dimensional approach can't analyze 3-dimensional flow effect in the vicinity of the train body. In this research, so as to overcome this weak point, a prediction method of the wavefront of a compression wave using steady state solution has been used for the parametric study considering 3-dimensional effects of the interactions between trains and tunnels. The effective hood shapes were deduced in both cases of the train's entry into the tunnel on the single track and on a side of the double track. As a result, in case of the train's entry on a side of the double track, the increase of compression wave value propagated to the tunnel inside have appeared compared with the train's entry on the single track. Also, a horizontally convex elliptic hood shape is more effective at the train's entry on a side of the double track for the purpose of a decrease of wavefront gradient of a compression wave.

• Journal of the Korean Society of Mechanical Technology
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• v.20 no.6
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• pp.901-905
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• 2018

The objective of this study is to investigate the effect of torque variation on stress distributions in A-IMS module with both side tubular shaft yoke by numerically. In order to achieve this, the torque value was increased from 10Nm to 40Nm, and the results of this work were confirmed in terms of Von-mises Stress and the displacement characteristics. As the torque in module assembly was increased, the stress in tubular shaft york and splined shaft york was increased linearly. The indentation due to the steel ball was occurred in over $40N{\cdot}m$ torque which is over the yield strength condition. The largest displacement occurred in the tubular shaft yoke 1, however, it does not exceed the yield strength and is supposed to be restored due to the elasticity. Therefore, it was concluded that there is no problem for the manufacturing of A-IMS with both side tubular shaft yoke.

• Journal of Digestive Cancer Research
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• v.1 no.2
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• pp.100-103
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• 2013

A 79-year-old man was diagnosed with gastrointestinal stromal tumor (GIST) of the gastric cardia. We performed proximal subtotal gastrectomy and started imatinib therapy as adjuvant treatment after surgery. Whole body skin rash with urticaria was onset on 10 days after imatinib treatment, and the patient decided to stop imatinib because of side effect. After 3 months, PET CT revealed GIST was recurred at spleen and abdominal lymph nodes, abdominal wall. The patient was then restarted on imatinib therapy. On follow-up imaging studies, the tumor almost disappeared, but both pleural effusion and pericardial effusion were found. In this paper, we describe a case of clinical course and side effects in recurred GIST after adjuvant imatinib mesylate treatment.

• Physical Therapy Korea
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• v.25 no.2
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• pp.13-21
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• 2018

Background: After a stroke, the patient may have abnormal muscle tone due to abnormal alignment. Physical therapists have used stretching, neural mobilization other methods to treat patients after stroke. In addition, joint mobilization is also used to stimulation in pathway of cervical segmental region and to normal cervical spine alignment. Objects: The purpose of this study was to determine whether Maitland cervical spine mobilization has an immediate effect on muscle tone and stiffness of upper extremity. Methods: Thirty subjects were divided into a experimental group ($n_1=10$), a placebo group ($n_2=10$), and a control group ($n_3=10$). The Maitland cervical spine mobilization was applied in the supine position. Immediately after the intervention, muscle tone and stiffness of biceps brachii, brachioradialis, deltoid, and pectoralis major were measured using Myoton(R)PRO. In the placebo group, sham mobilization was applied to the fifth and sixth cervical vertebra, and the control group was instructed to control breathing. Results: In the experimental group, significant differences were found in muscle tone and stiffness of biceps brachii and brachioradialis in comparison with the affected side and the non-affected side before the intervention (p<.05), whereas there was no significant difference after the intervention (p>.05). Muscle tone of biceps brachii on the non-affected side and pectoralis major on the affected side was significantly decreased before and after the intervention (p<.05). The placebo and control group showed no changes on the non-affected and affected side, and no significant differences were detected before and after the intervention. All the groups revealed no significant differences in muscle tone and stiffness of upper extremity before and after the intervention. Conclusion: This study suggests that the application of Maitland cervical spine mobilization enhanced muscle tone of upper extremity on the involved side symmetrically, and influenced a decrease in muscle tone.

• The korean journal of orthodontics
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• v.22 no.2 s.37
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• pp.297-308
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• 1992

The effect of orthodontic force on the collagenase and phosphatase activities of the adjacent alveolar bone was evaluated. Maxillary canines of male cats were treated orthodontically with closed coil spring so as to exert about 80g force. Sixteen cats were equally divided into one control group and seven experimental groups (12 hrs, 24 hrs, 36 hrs, 2 days, 3 days, 5 days and 7 days after orthodontic treatment). After sacrificing all animals on experimental intervals, collagenase, acid phosphatase (ACP) and alkaline phosphatase (ALP) activities were determined in the pressure and tension sides of alveolar bones. ACP activities increased in both the pressure and tension sides, but significantly increased in the pressure side continuously. ALP activities increased in the tension side at early stage (1-2 days after treatment), but changed small amount in the pressure side. Collagenase activities increased in the pressure side, especially at late stage (5-7 days after treatment). These results suggest that (1) orthodontic fore force increases the ACP, ALP and collagenase activities generally and (2) activities of ACP and collagenase increase in the pressure side, but that of ALP in the tension side and (3) activities of ACP and ALP increase at early stage, but that of collagenase at late stage after orthodontic treatment. Therefore it is shown that there are time differences in the formation and destruction of organic and inorganic components in the bone metabolism of alveolus with application of the orthodontic forces.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.3
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• pp.57-65
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• 2015

PURPOSE: The purpose of this study was to investigate the effect of balance training on different support surface (affected and non-affected sides) on the balance and gait function of chronic stroke patients. METHODS: The patients were randomly assigned to 1 of 4 groups. Group 1 received balance training on the stable surface, group 2 received balance training on the unstable surface, group 3 received balance training on different support surface (affected side: stable surface, non-affected side: unstable surface), and group 4 received balance training on different support surface (affected side: unstable, non-affected side: stable). Twelve sessions (30 min/d, 3 times/wk for 4 wk) were applied. There were assessed before and after the intervention with Balancia, functional reach test (FRT), lateral reach test (LRT), timed up-and-go (TUG), and 10-meter walking test (10MWT). RESULTS: After the training, all of the groups improved significantly than before training in Balancia, FRT, LRT, TUG, and 10MWT. There were significantly variable in sway distance, FRT, LRT, TUG, and 10MWT among the 4 groups. Post hoc analysis revealed that the group 3 had significantly higher results than other 3 groups in sway distance, and FRT, LRT, TUG, and 10MWT. CONCLUSION: Balance training on different support surface (affected side: stable surface, non-affected side: unstable surface) could facilitate a stronger beneficial effect on balance and walking ability than other balance trainings on different support surface in patients with stroke.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.4
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• pp.945-949
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• 2005

The objective of this study is to investigate the inhibitor effects of an traditional oriental herb, Sophora flavescens on the pancreatic & cardiac side effects of chemotherapy were studied by using Bl6-BL6 melanoma-injected C57BL6 mouse tumor model. In this study, the effects of an traditional oriental herb, Sophora flavescens, on the side effects of chemotherapy were studied using B16 melanoma-injected C57BL6 mouse tumor model. Anticancer drugs widely used in clinical situation. Sophora flavescen has significant effect on the reduction of the side effects of chemotherapy. Water extract of Sophora flavescens significantly inhibited cisplatin-induced increase of amylase (AMY) which is a good indicator of pancreatic toxicity. Sophora flavescens extract does not decrease the anti-tumor activity of cisplatin showing that it can selectively inhibit side effects of anticancer drugs preserving beneficial effect. Theses results suggest a possibility that Sophora flavescens extract can be used for cancer patients for the reduction of the side effects and improving the quality of life during chemotherapy of cancer patients.

• The Korean Journal of Food And Nutrition
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• v.29 no.2
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• pp.275-282
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• 2016

Recently, increased caffeine intake has led to an increase in caffeine addiction and withdrawal symptoms. Coffee is surreptitiously consumed in as an additive to milk and caramel. There are few studies on how coffee affects the health of modern people. The purpose of this study is to determine the efficacy and side effects of coffee by awareness of coffee consumption patterns among college students, who are the principal consumers. A survey was conducted from May 11 to 17, 2015 and 302 questionnaires were analyzed. The respondents were 140 men (46.4%) and 162 women (53.6%). In terms of coffee additives, 151 (50.0%) respondents chose 'americano' and 111 (36.8%) 'variation'. The frequency of coffee intake and sleep time for college students was negatively correlated, with the correlation coefficient of -0.145 and significance probability of 0.019. The group that was 'positively' aware of the principal ingredients of coffee had a higher level of academic training than those with 'negative' awareness (p=0.000). Women recognized a larger number of side effects than men: 1.99 and 1.36, respectively, on average (p=0.001). 'Time for consumption' had statistically significant effects on the side effects of coffee consumption: consumption before/after lunch, before/after supper and before going to bed led to 0.4 times (p=0.048) and 0.3 times (p=0.023) more side effects, respectively, than consuming coffee after getting up and before/ after breakfast. Excessive caffeine intake through coffee led to limited sleep time and poorer learning concentration. The guidelines for proper coffee consumption should be created to help students consume coffee properly so that it will not affect sleep, learning concentration or adversely affect health.

• Journal of Ocean Engineering and Technology
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• v.31 no.4
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• pp.266-273
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• 2017

In recent years, LNG bunkering terminals are needed to supply LNG as fuel to meet the emission requirements of the International Maritime Organization (IMO). A floating LNG bunkering terminal (FLBT) is one of the most cost-effective and environmentally friendly LNG bunkering systems for storing LNG and transferring it directly to an LNG fuel vessel. The FLBT maintains its position using mooring systems such as spread mooring and turret mooring. The loads on the vessel and mooring lines must be carefully determined to maintain their positions within the operable area. In this study, the wind loads acting in several side-by-side arrangements on the FLBT and LNG-BS were estimated using wind tunnel tests in the Force Technology, and the shielding effect due to the presence of ships upstream was evaluated. In addition, the empirical formulations proposed by Fujiwara et al. (2012) were used to estimate the wind force coefficients acting on the FLBT and those results were compared with experimental results.

• Journal of the Korean Wood Science and Technology
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• v.26 no.4
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• pp.6-12
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• 1998

Test results of domestic softwood lumber were presented to examine the notch effect of beams and compare to present AIJ(Architecture Institute of Japan) formula in notched wood member especially positioned in bottom side (tension side) of a beam. Notched lumber was tested under following condition : each specimen supported simply, and subjected to third-point loading at points of 1/3 of the span length. Notch was located opposite side to loading direction and notch depth were 1/6, 1/4, 1/3 of beam depth. Deflection and load were measured by digital dial guage each in 25kgf increment. Bending test results were as follows; Mpro/Mmax range (proportional and maxium bending moment ratio in notched beam) was 0.5 - 0.65. It was considered that maxium bending moment was about 1.5 times to proportional bending moment in notched beam and showed same tendency in the test result of ordinary wood specimens. AU standard formula for the tension side notch, Mmat = 0.6 ${\times}$ (Zo $\sigma$), the constant 0.6 was suitble for notch ratio(notch depth to beam depth) 1/6, but this ratio for 1/4, and 1/3 was not. So it is preferable to accept smaller value than 0.6 for notch ratio more than 1/3. These experiment results showed critical effect in tension side notched wood beam especially in greater than notch ratio 1.3 of wood beam. From the above results, it is recommened to revise design formula adoptable to domestic wood constructon member with tension side notched member.