• Applied Chemistry for Engineering
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• 제10권5호
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• pp.743-747
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• 1999

The component polymer was modified to enable the formation of intermolecular hydrogen bonding in the immiscibile polystyrene(PS)/polymethacrylate(PMA) blends. The mole percentages of hydroxystyrene of the poly(styrene-co-4-hydroxystyrene) copolymer(modified polystyrene, MPS) were controlled to 7%, 10% and 18%, respectively. MPS was used with PMA to study the variation of the miscibility in blends. PMA which had such different length of side chain as methyl, butyl, hexyl and ethylhexyl, respectively, was selected to study the effect of side chain length on the formation of intermolecular hydrogen bonding. As the hydroxyl content of MPS increased, the formation of intermolecular hydrogen bonding increased. The length of side chain of PMA had enormous effect on the miscibility of blend as confirmed from the result of cloud point measurement. As the length of side chain increased, the formation and the strength of intermolecular hydrogen bonding decreased severely due to the steric effect and the increased chain mobility.

• Bulletin of the Korean Chemical Society
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• 제23권5호
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• pp.688-692
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• 2002

The aminomethylation of phenols with para-substituents by the Mannich reaction has successfully been accomplished to produce the Mannich bases 2-6. The compounds 7-8 have also been synthesized in order to identify the effect of the side arms and t he macrocycle in the complex formation. Protonation constants and stability constants of the double armed diaza-18-crown-6 ethers 2-7 with metal ions have been determined by potentiometric method at 25 $^{\circ}C$ in 95 % methanol solution. Under a basic condition (pH > 8.0), the double-armed crown ethers 2-6 revealed stronger interaction with divalent metal ions than the simple diazacrown ether 1. The stability constants with these metal ions were Co 2+ < Ni2+ < Cu2+ > Zn 2+ in increasing order, which are in accordance with the order of the Williams-Irving series. The stability constants with alkali earth metal ions were Ca 2+ < Sr 2+ < Ba 2+ in increasing order, which may be explained by the concept of size effect. It is noteworthy that the hosts 2-6, which have phenolic side arms and a macrocycle, bind stronger with metal ions than the hosts 1 and 7. On the other hand, the host 8, which has phenolic side arms with a pyperazine ring,provided comparable stability constants to those with the host 3. These facts demonstrate that phenolic side arms play a more important role than the azacrown ether ring in the process of making a complex with metal ions especially in a basic condition. In particular, the log KML values for complexation of divalent metal ions with the hosts 2-6 had the sequence, i.e., 2 (R=OCH3) < 3 (R=CH3) < 4 (R=H) < 5 (R=Cl) < 6 (R=CF3). The stability constants of the hosts 5 and 6 containing an electron-withdrawing group are larger than those of the hosts 2 and 3 containing an electron-donating group. This substituent effect is attributed to the solvent effect in which the aryl oxide with an electron-donating group has a tendency to be tied strongly with protic solvents.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제21권2호
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• pp.63-71
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• 2010

Objectives : The aim of this study was to investigate the effect of the clinical and demographic variables such as body weight, dosage, family history of attention-deficit hyperactivity disorder (ADHD), and psychiatric co-morbidity on the side-effects of OROS-Methylphenidate (OROS-MPH), and to evaluate the relationship between drug response and side effect severity. Methods : A total of 144 children (ages 6-18) with diagnosed ADHD were treated with OROS-MPH. Children were examined at baseline and after 1, 3, 6, 9, and 12 weeks of each treatment condition. The stimulant drug side effect rating scale (SERS), pulse rate, systolic blood pressure, diastolic blood pressure, and electrocardiogram (ECG) were evaluated to assess side effect profiles. Changes in these parameters from baseline were examined and analyzed. Results : Anorexia (30.95%) and insomnia (13.10%) were the most commonly reported side effects during this study. Insomnia and loss of appetite score increased at one week follow-up, but was sustained or decreased as treatment progressed. Small but significant increases in pulse rate and diastolic blood pressure were observed during treatment ; however, no clinically meaningful changes in ECG parameters were noted during the study. Low body weight, high dosage of OROS-MPH, and family history of ADHD were associated with cardiovascular side effect. In contrast, there was no significant relationship between OROS-MPH treatment response and the severity of side effect and no difference resulted between the responder and non-responder groups with respect to OROS-MPH dosage in the 12 weeks of follow-up. Conclusion : To the best of our knowledge, this study is the first Korean study to investigate comprehensive side effect profiles and their correlates in OROS-MPH treatment for ADHD children. OROS-MPH was well tolerated with no clinically significant side effects during the treatment period. In conclusion, low body weight, high dosage of OROSMPH, and family history of ADHD could be used as predictive factors in increasing pulse rate and blood pressure.

• Journal of the Korean Geographical Society
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• 제43권1호
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• pp.71-86
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• 2008

The ambiguity of spatial language can be a source of communication problems. For instance, the 'the opposite side' in a sentence such as 'where is the opposite side of building X' can mean more than one direction. Research interests are focused on the directions of a spatial language 'the opposite side'. This study also explored the effect of geometric properties such as reference object's shape and distance from the reference object and spatial reference frame in the comprehension of 'the opposite side'. The assessment tasks used consisted of rating how appropriate the sentence 'where is the opposite side of building X' was to describe a series of pictures. The results of experiment suggest that 'the opposite side' means in most cases more than one direction simultaneously. Changing spatial reference frame has significant effects on individuals' rating of the tasks. However, while reference object's shape (prolonged building) has a consistent effect of the ratings given, the distance from the reference object (shortened road width) has limited influence in comprehending the tasks.

• International Journal of High-Rise Buildings
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• 제11권4호
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• pp.241-263
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• 2022

The conventional wind and twisted-wind effect on aerodynamic properties of neighboring buildings arranged in side-by-side and tandem systems at 2B and 5B spacings are systematically investigated by large eddy simulation. Different physical interactions between different wind profiles and neighboring buildings will be deeply understood. The neighboring-building system under two different types of wind profiles, i.e., conventional wind profile (CWP), twisted wind profiles (TWP) with the maximum twisted angle of 30°, is used to evaluate the variation of physical mechanism between wind and buildings. Aerodynamic characteristics including mean and RMS pressure coefficient, and velocity field were systematically analyzed and compared between different scenario. It was found that the distribution of mean pressure, root-mean-square x velocity and the streamline of wind flow for TWP greatly deviated from CWP, and the effect of TWP on the downstream building, was drastically different from that of CWP, such as the size of vortexes after the lower stream building being bigger when exposed to TWP, and the mean pressure distribution on the building surfaces are also different. Moreover, evidence of buildings arranged in side-by-side and tandem configurations having interchangeable properties under TWP was also discovered, that two buildings being arranged side-by-side exposed to TWP could be identified as being arranged in tandem with a different wind twist angle, or vice versa.

• The Journal of Pediatrics of Korean Medicine
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• 제28권4호
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• pp.96-107
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• 2014

Objectives The purpose of this study is to understand what caregivers think advantageous and disadvantageous regarding Acupoint sticking Dog-days. Also, to know whether Acupoint sticking in Dog-days affect vital signs, and to investigate if occurrence of side effects are related to application duration, sweat, or compliance to precautionary measures. Methods Survey has been handed out to parents of the children who took Acupoint sticking in Dog-days. 10 days after the first dose was administered, survey was performed to examine any side effect occurrences, characteristics of sweat, duration of application, parents' thought about this therapy. Also, vital signs were checked before the first dose, and 10 days after to see any differences in vital signs in regards to this therapy. Results Preferable opinions about Acupoint sticking in Dog-days are 'convenient than herbal medications' (76.5%), 'less reluctance of child' (47.1%), 'reasonable price' (20.6%), 'good effectiveness' (17.6%), 'less side effect' (14.7%), 'no worry about agrochemicals or heavy metals uptake' (11.8%). Downsides were 'difficult to admit to hospital right on the Dog-days' (73.5%), 'no conspicuous effectiveness' (11.8%), 'expensive' (5.9%), 'reluctance of child' (2.9%). Vital sign differences were minimal when examined before and after Acupoint sticking in Dog-days. Side effects occurred 5 times in 34 cases, and they were erythema, itchiness, and hot sensation. There were no scars or blisters reported. All 5 cases were resolved without any interventions within 3 days. Conclusions Acupoint sticking in Dog-days doesn't affect vital signs. Severe side effect is rare, reported side effects were relatively mild, suggesting that it may be safe and well-tolerated. 'Convenience' (76.5%) is biggest advantage of Acupoint sticking in Dog-days and 'less reluctance of child' is also big advantage of Acupoint sticking in Dog-days. 'Difficulty to admit to hospital right on the Dog-days' (73.5%) is biggest disadvantage of Acupoint sticking in Dog-days.

• Transactions of Materials Processing
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• 제15권8호
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• pp.556-561
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• 2006

Most of auto-body members are composed of stamping parts. These parts have the non-uniform thickness and plastic work hardening distribution during the forming process. This paper is concerned with the side impact analysis of the ULSAB-AVC model according to the US-SINCAP in order to compare the crashworthiness between the model with and without considering the forming effect. The forming effect is ca]ciliated by one-step forming analysis for several members. The crashworthiness is investigated by comparing the deformed shape of the cabin room the energy absorption characteristics and the intrusion velocity of a car. The result of the crash analysis demonstrates that the crash mode, the load-carrying capacity and energy absorption can be affected by the forming effect. It is noted that the design of an autobody should be carried out considering the forming effect for accurate assessment of crashworthiness.

• KDI Journal of Economic Policy
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• 제37권1호
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• pp.19-44
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• 2015

This paper examines the effect of the global financial crisis on corporate investment in Korea. Specifically, the crisis was considered to have possibly constrained firm-level investment as the negative shock to the credit supply dramatically unfolded. As Duchin et al. (2010) demonstrated, if a negative supply-side shock is evident during a crisis period, larger cash holdings before the crisis will lead to fewer constraints to corporate investment, or vice versa. In order to investigate the supply-side effect of the crisis, we use firm-level financial data, including firms listed on the Korean stock market as well as small and medium-sized enterprises. We find that corporate investment declined significantly after the crisis, even if we control for factors associated with the demand side, such as contemporaneous capital productivity and cash flow. More importantly, the decline is positively and significantly related to cash holdings before the crisis, implying the negative effect of a credit supply shock. Small and medium enterprises experienced relatively sharp investment declines compared to those of larger firms, and the relationship between pre-crisis cash amounts and the degree of investment decline is greater than that in large firms. Additionally, we examine whether the negative effect persists up to the present, finding evidence that the cash-investment relationship continues in small and medium-sized enterprises.

• Journal of Acupuncture Research
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• 제19권4호
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• pp.27-41
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• 2002

Objective : The purpose of this study is to compare the effect of two other groups(Group A and B) which were treated with two other auricular acupuncture therapy to quit smoking. Methods : Seventy three high-school students were devided in two groups. Group A was treated with auricular acupuncture therapy by burying a needle in one side ear. Group B was not only treated with auricular acupuncture therapy by burying a needle in one side ear, but also treated with venesection on the other side ear. The effects of auricular acupuncture therapy to quit smoking were evaluated at two weeks and six months after the therapy. Results : Group A's score to quit smoking after the auricular acupuncture therapy was higher than Group B's score. Conclusions : Treating with auricular acupuncture therapy by burying a needle in one side ear and venesection on the other side, was effective neither on decreasing the amount of smoking nor on decreasing the desire to smoke compared with the only needle burying treatment.

• Journal of Ocean Engineering and Technology
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• 제15권3호
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• pp.75-80
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• 2001

The elastic plastic fracture toughness of this material is evaluated by the an unloading compliance method according to the ASTM E813-97 and E1152-97 method on the smooth and side groove 1CT specimens. The effect of smooth and side groove is studied on the material tearing modulus and characterizes the crack tip field under the plane stress and strain. SG-365 steel is observed that J-R curve and Tmat value decrease as 0%, 20%, 30%, and 40%. The 40% side grooved specimen is very useful in estimation of the $J_IC$. Because it is much easier than the smooth specimen to the onset of the ductile tearing by the R curve method. Besides. it improves the accuracy of toughness values, decreases the scattering the them and tunneling and shear lip by the side groove. Applicability of tearing modulus($T_J$ proposed by paris et al as instability panameter for this material is investigated.