• Bioinformatics and Biosystems
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• v.2 no.1
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• pp.17-23
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• 2007

Shot interfering RNA (siRNA) can be used to silence specific gene expression and have many potential therapeutic applications. However, how to design an effective siRNA is still not clear. Highly effective siRNA has sequence-specific properties which are low G/C content, low internal stability at the sense strand 3'-terminus, sense strand base bias(position 1 is G/C, position 19 is /AU). Recently, mRNA secondary structure playsan important role in RNAi. Target site of siRNA in high-ordered structure (i.e hairpin loop, multi loop) or base pair of many hydrogen bonds dramatically reduce function of siRNA mediated gene silencing. Possible off-target effects of siRNA is detecting from BLAST search.

• Design & Manufacturing
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• v.2 no.4
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• pp.37-43
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• 2008

Supplementary features in injection molded products, which are boss, rib and snap fit, are mainly located in the products. These features might make molding flow improper in injection processing and consequently give rise to some of molding troubles such as short shot and hesitation. The sink mark on boss parts is generated by the volumetric shrinkage that is caused by both the molding thickness and the closed boss height. The volumetric shrinkage is affected by packing pressure and its amount tends to decrease by increasing the packing pressure. The packing pressure can therefore increase flow rate to a boss part and causes the sink mark depth to increase. As the molding thickness and the closed boss height in the boss part can increase the part volume, these may yield bad solidifying and also extend the molding cycle. In this paper, both the injection molding test and the flow analysis were carried out to investigate the effect of sink marks generated in the boss part of injection molded products.

• Elastomers and Composites
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• v.51 no.4
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• pp.263-268
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• 2016

In the polymer shaping process that uses molds, the quality of the molded products is determined not only by the flow of the (molten) polymer but also by the air venting in the cavity. Inadequate air venting in the cavity can cause defects in the product, such as voids, short shot, or black streaks. As it is critical to consider the location and size of the vents for proper venting of the air in the cavity, a method that predicts the flow of air and material is required. The venting of air by the flow of rubber inside the cavity was simulated by using a multi-phase computational fluid dynamics method. Through computer simulation, the interface of rubber and air over time was predicted. Then, the velocity and pressure distribution of the venting air were observed. Our research proposes a fundamental method for analyzing the multi-phase flow of polymer materials and air inside the cavity of a mold.

• Journal of Digital Convergence
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• v.11 no.7
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• pp.297-304
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• 2013

This research explores the effect of TV news camerawork and viewers' involvement on memory of news through experiment. For this experimental research, 2 groups of subjects composed of university students were exposed to different types of TV news and responded to survey questions which were analysed by SPSS program. This research found that camerawork of TV news doesn't have an effect on short-term memory but on long-term memory. Though the fact viewers' involvement has a positive effect on shot-term and long-term memory was found, interactive effect of viewers' involvement and camerawork as an peripheral clue was not found.

• Transactions of the Korean Society of Automotive Engineers
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• v.11 no.5
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• pp.50-59
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• 2003

It was known that high pressure injection is an effective method to enhance thermal efficiency and decrease exhaust emissions in diesel engines. If injection pressure becomes ultra high, it is predicted that there may be a suitable injection pressure which the enhancement rate of spray characteristics is moderate. Also, there may be a limit injection pressure which spray characteristics is reversed and get worse. But these are unknown. To investigate a suitable injection pressure and a limit injection pressure, ultra high pressure injection equipment(UHPIE), which can realize the injection pressure of 3,200bar, was developed. UHPIE is a basic apparatus of single shot injection, and ultra high pressure was achieved by second stage rapid compression in short time. From the evaluation of UHPIE, a injection curve like a conventional diesel engine(jerk type) was realized. Also, it was proved that repetition of experiment was excellent. Therefore it was found that there was no problem to perform the study on the ultra high pressure injection with UHPIE. Consequently, the foundation of the study on ultra high pressure injection could be established.

• Korean Journal of Optics and Photonics
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• v.13 no.5
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• pp.435-441
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• 2002

In this paper, we propose an optimal 2-dimensional construction algorithm of a code family for a high-speed optical code division multiple access network. The optimal 2-D code family generated by search algorithm has better spectrum efficiency than previous codes, having relatively many code sets with short code length and the same or lower BER. Using the optimal 2-D code, OCDMA systems make it possible to utilize the spectrum more efficiently than WDM systems. The probability of bit error for high-speed OCDMA transmissions is calculated as a function of the number of users in the presence of receiver and shot noise(additive white Gaussian noise).

• Journal of Korea Multimedia Society
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• v.22 no.8
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• pp.874-886
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• 2019

To delve into the semantic gap problem of the automatic video summarization, we focused on an endogenous ERP responses at around 400ms and 600ms after the on-set of audio-visual stimulus. Our experiment included two factors: the topic exploration of experimental conditions (Topic Given vs. Topic Exploring) as a between-subject factor and the topic relevance of the shots (Topic-Relevant vs. Topic-Irrelevant) as a within-subject factor. For the Topic Given condition of 22 subjects, 6 short historical documentaries were shown with their video titles and written summaries, while in the Topic Exploring condition of 25 subjects, they were asked instead to explore topics of the same videos with no given information. EEG data were gathered while they were watching videos in real time. It was hypothesized that the cognitive activities to explore topics of videos while watching individual shots increase the amplitude of endogenous ERP at around 600 ms after the onset of topic relevant shots. The amplitude of endogenous ERP at around 400ms after the onset of topic-irrelevant shots was hypothesized to be lower in the Topic Given condition than that in the Topic Exploring condition. The repeated measure MANOVA test revealed that two hypotheses were acceptable.

• Journal of Broadcast Engineering
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• v.25 no.6
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• pp.861-869
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• 2020

We introduce the application that automatically makes several images stored in user's device into one video by using the different climax patterns appearing for each film genre. For the classification of the genre characteristics of movies, a climax pattern model style was created by analyzing the genre of domestic movie drama, action, horror and foreign movie drama, action, and horror. The climax pattern was characterized by the change in shot size, the length of the shot, and the frequency of insert use in a specific scene part of the movie, and the result was visualized. The model visualized by genre developed as a template using Firebase DB. Images stored in the user's device were selected and matched with the climax pattern model developed as a template for each genre. Although it is a short video, it is a feature of the proposed application that it can create an emotional story video that reflects the characteristics of the genre. Recently, platform operators such as YouTube and Naver are upgrading applications that automatically generate video using a picture or video taken by the user directly with a smartphone. However, applications that have genre characteristics like movies or include video-generation technology to show stories are still insufficient. It is predicted that the proposed automatic video editing has the potential to develop into a video editing application capable of transmitting emotions.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.9 no.6
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• pp.788-801
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• 1998

Meteor Burst Communication can provide effective and economical means of communication where long distance VHF NLOS data transmission is needed ; often ranges more than 1000 km. It has been, however, so far considered unsuitable for short distance application because of phenomenal decrease in burst durations, which leads to decreation of total duty rate of the system. This paper extensively analyzes characteristics of shot distance MB(Meteor Burst) path and shows the low duty rate may be improved by increasing burst rate through adapting antennal beam width to cover entire hot-spot region in the space and, by compensating effective burst length throughcutting down man-made noises introduced by antennal. Based on the analysis, we are developed a small-opening-cavity antennal, especially designed for short distance MB path. In operation, the antenna is to be buried under ground surface so as to improve directivity and reduces noise introduction. The antennal exhibits power gain of 3 dB with 90 degree beam width and thus enables to illuminate entire hot-spot regions with the elevation angle of 8-90 degree which is the case of transmission less than 100 km. Directivity horizontal to earth surface is suppressed to minimum which enables to cut man-made noises from near-by sources down to more than 3 dB from the level reported with conventional 4 element Yagi. A series of experiments performed on 100km MB paths have conformed that, with the antenna installed at receiving site, the burst rate and duration time have been noticed to increase by 10 and 20 percent respectively from the values obtained by conventional 4-element Yagi antennal under same testing condition.

• Tuberculosis and Respiratory Diseases
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• v.43 no.6
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• pp.852-861
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• 1996

Background : Many clinicians have experienced the difficulty of decision on termination of antituberculosis chemotherapy after the 6th month due to relapse of disease. There is still controversy in the effect of 2S(K)HRZ/4HRZ 6-month short course chemotherapy including pyrazinamide for 6 months in patiems with pulmonary tuberculosis. And there is no long term follow-up study of 6-month short course chemotherapy for pulmonary tuberculosis in korea. So we had performed the study to find the result of 6-month antituberculosis chemotherapy for 4 years. Method : We studied prospectively the effect of 2S(K)HRZ/4HRZ in one hundred-fifty patients with pulmonary tuberculosis and followed up fifty-nine patients for more than 1 year to 4 years after the completion of 6-month short course therapy. Results : 1) Out of one hundred-fifty patients, seventy-two patients(48%) completed the prescribed 6-month chemotherapy. Sixty-eight patients(45.3%) have experienced premature discontinuation and the most common cause of premature discontinuation was drop-out against advice(thirty-six patients, 24%). Ten patients(6.7%) were treated beyond the 6 months mainly due to irregular treatment. 2) Fifty-nine patients(81.9%) among seventy-two patients with completed treatment have been followed up for more than 1 year and 32 patients(44.4%) for more than 4 years. There was three relapse patients of whom two patients have experienced relapse of pulmonary tuberculosis within 1 year after the termination of chemotherapy. 3) Among one hundred-thirty-four patients who have been assessible for more than two months of chemotherapy, including the patients who experienced within 2 months, there were eighty-two patients(61.2%) who have experienced adverse reactions and the treatment regimen was changed only in thirteen patients(9.7%). The most frequent cause of adverse reactions was arthralgia and/or hyperuricemia, which had occurred in 33 patients(24.6%). Conclusion : In a university hospital in Korea, 6-month shot course chemotherapy of 2S(K)HRZ/4HRZ had unnegligible relapses and premature discontinuation. Therefore, change of the regimen might be carefully considered by drug susceptibility results. Close monitoring of patients, retrial of sputum exam and radiologic evaluation during treatment might be required in the endemic area of drug resistant strains like in Korea. Further study about the effect of 6-month short course chemotherapy including pyrazinamide for 6-month might be needed.