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Multiple Relationships Between Impairment, Activity and Participation-based Clinical Outcome Measures in 200 Low Back Pain

  • Chanhee Park
    • Physical Therapy Korea
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    • v.30 no.2
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    • pp.136-143
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    • 2023
  • Background: The International Classification of Functioning, Disability and Health (ICF) model, created by the World Health Organization, provides a theoretical framework that can be applied in the diagnosis and treatment of various disorders. Objects: Our research purposed to ascertain the relationship between structure/function, activity, and participation domain variables of the ICF and pain, pain-associated disability, activities of daily living (ADL), and quality of life in patients with chronic low back pain (LBP). Methods: Two-hundred patients with chronic LBP (mean age: 35.5 ± 8.8 years, females, n = 40) were recruited from hospital and community settings. We evaluated the body structure/function domain variable using the Numeric Pain Rating Scale (NPRS) and Roland-Morris disability (RMD) questionnaire. To evaluate the activity domain variable, we used the Oswestry Disability Index (ODI) and Quebec Back Pain Disability Scale (QBDS). For clinical outcome measures, we used Short-form 12 (SF-12). Pearson's correlation coefficient was used to ascertain the relationships among the variables (p < 0.05). All the participants with LBP received 30 minutes of conventional physical therapy 3 days/week for 4 weeks. Results: There were significant correlations between the body structure/function domain (NPRS and RMD questionnaire), activity domain (ODI and QBDS), and participation domain variables (SF-12), rending from pre-intervention (r = -0.723 to 0.783) and postintervention (r = -0.742 to 0.757, p < 0.05). Conclusion: The identification of a significant difference between these domain variables point to important relationships between pain, disability, performance of ADL, and quality in participants with LBP.

Prolonged Exposure to Lipopolysaccharide Induces NLRP3-Independent Maturation and Secretion of Interleukin (IL)-1β in Macrophages

  • Hong, Sujeong;Yu, Je-Wook
    • Journal of Microbiology and Biotechnology
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    • v.28 no.1
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    • pp.115-121
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    • 2018
  • Upon sensing of microbial infections or endogenous danger signals in macrophages, inflammasome signaling plays a significant role in triggering inflammatory responses via producing interleukin (IL)-$1{\beta}$. Recent studies revealed that active caspase-1, a product of the inflammasome complex, causes maturation of inactive pro-IL-$1{\beta}$ into the active form. However, the underlying mechanism by which this leaderless cytokine is secreted into the extracellular space remains to be elucidated. In this study, we demonstrated that prolonged lipopolysaccharide (LPS) treatment to macrophages could trigger the unexpected maturation and extracellular release of IL-$1{\beta}$ through a nucleotide-binding oligomerization domain-like receptor family, pyrin domain-containing 3 (NLRP3)-independent manner. Short-term treatment (less than 6 h) of LPS induced robust production of the IL-$1{\beta}$ precursor form inside cells but did not promote the maturation and secretion of IL-$1{\beta}$ in bone marrow-derived macrophages or peritoneal macrophages. Instead, prolonged LPS treatment (more than 12 h) led to a significant release of matured IL-$1{\beta}$ with no robust indication of caspase-1 activation. Intriguingly, this LPS-triggered secretion of IL-$1{\beta}$ was also observed in NLRP3-deficient macrophages. In addition, this unexpected IL-$1{\beta}$ release was only partially impaired by a caspase-1 and NLRP3 inflammasome inhibitor. Collectively, our results propose that prolonged exposure to LPS is able to drive the maturation and secretion of IL-$1{\beta}$ in an NLRP3 inflammasome-independent manner.

Comparison of Ovariectomy and Ovariohysterectomy in Terms of Postoperative Pain Behavior and Surgical Stress in Dogs (개에서 난소자궁절제술과 난소절제술 후 나타나는 통증 행동과 스트레스 반응의 비교)

  • Lee, Scott-S.;Lee, Seung-Yong;Park, Se-Jin;Kim, Young-Ki;Seok, Seong-Hoon;Hwang, Jae-Min;Lee, Hee-Chun;Yeon, Seong-Chan
    • Journal of Veterinary Clinics
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    • v.30 no.3
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    • pp.166-171
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    • 2013
  • This study was conducted to evaluate the clinical relevance and effectiveness of ovariectomy (OVE) and ovariohysterectomy (OVH) in terms of postoperative pain behavior and surgical stress. Thirteen healthy intact mongrel purpose-bred female dogs were used in this study. OVE was performed in six dogs whereas OVH was performed in seven dogs. Prior to, 1, 2, 4, 6, 12, and 24 h after surgery, pain assessment was performed by using the Short form of Composite Measure Pain Scale (CMPS-SF) and blood analysis for the determination of glucose, creatine kinase (CK), and cortisol were done. Also, surgical time, duration of anesthesia, and incision length were compared between two groups. As a result, OVH group as opposed to OVE group showed significantly longer in surgical time, duration of anesthesia, and incision length. Also, based on the two-way ANOVA test, the CMPS-SF had significant differences (p < 0.05) between two groups, with the OVE dogs having lower values at 1, 2, 4, and 6 h postoperatively. In addition, in terms of CK, the value at 1, 2, 4, 6, and 12 h were significantly (p < 0.05) increased from the baseline value for the OVH group. However, as for CK in OVE group, the values at 4, 6, and 12 h were significantly increased from the baseline value. As for blood glucose, a significant (p < 0.05) increase from the baseline was shown at 1 h postoperatively in OVH group and no significant increase was shown in OVE group. In terms of serum cortisol level, the values at the 1 and 2 h were significantly (p < 0.05) increased from the baseline value for both groups. In conclusion, our study has shown that OVE can be considered as a superior choice in terms of sterilization technique in female dogs, considering shorter incision length, surgical time, duration of anesthesia along with lower pain and surgical stress response than OVH.

Evaluation of Cognitive Functions, Depression, Life Satisfaction among the Elderly Receiving Visiting Nursing Services (방문간호 대상 노인의 인지기능, 우울 및 생활만족도 평가)

  • Won, Jong-Soon;Kim, Kye-Ha
    • Journal of Korean Academy of Nursing
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    • v.38 no.1
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    • pp.1-10
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    • 2008
  • Purpose: The purpose of this study was to examine cognitive functions, depression, and life satisfaction among the elderly receiving visiting nursing services. Methods: The subjects of this study consisted of 221 elderly individuals who were receiving visiting nursing services from a public health center located in Gyeonggi-do. The Mini-mental State Examination Korea version (MMSE-K), Geriatric Depression Scale-short form-Korea version (GDS-K), and Life Satisfaction Scale were utilized to determine cognitive functions, depression, and life satisfaction, Collected data was analyzed by the SPSS PC Win 12,0 program. Results: The prevalence of cognitive impairment (MMSE-K$\leq$24) was 86.4%, and the proportion of severe depression (GDS-K$\leq$10) was 22,6%, Older age, lower education, and low income were associated with cognitive impairment, and low education, no religion, and low income were associated with depression. Cognitive function negatively correlated with depression. Life satisfaction level was fairly low and was not associated with any variables. Conclusion: The high prevalence of cognitive impairment and low life satisfaction status were determined among low-income elderly who were registered at a visiting health care center. Thus, in the future at visiting health care services, efficient and various programs for the elderly should be tried, to improve cognitive functions and reduce depression. Additionally, consistent evaluation studies for those programs will be required.

A Study on Korean Man's Head Ornaments in the Joseon Dynasty - Focusing on Pungjam and Kwanja - (조선시대 남자(男子)의 수식(首飾) 연구(II) - 풍잠(風簪)과 관자(貫子)를 중심(中心)으로 -)

  • Chang, Sook-Whan
    • Journal of the Korea Fashion and Costume Design Association
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    • v.12 no.2
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    • pp.1-20
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    • 2010
  • This thesis is about "manggon" that holds down man's top knot hair and its accessaries "pungjam", "kwanja". manggon was seen first time in the mural of Donwhang kae won chon bo during T'ang period (713-756). The "Tu Aek Ra" manggon shown in this mural would be the origin and beginning of maggon's usage. Also the "Sha" that was placed on top of the hair for decoration purpose is believed to be a former form of "manggon" Before the short hair cut was enforced, wearing the "kwan"(head gear) was considered as an impotant etiguette. Thus the head gear was treasured and the manggon which was the most essential piece to cover down the hair before to put on the head gear was regarded as the most important piece. However, since the manggon was tied very tightly around the forehead, manggon caused some sickness. From my private collections of man's head gears and ornament, 121 items were selected and used for analysis and the followings were found: 1. Pungjam was divided into 8 categories according to its shape and a research was made on its unique structural characteristic on each categories. 2. Kwanja's material and design that were used are all in accordance to the historical recordings.

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Nexus between Indian Economic Growth and Financial Development: A Non-Linear ARDL Approach

  • KUMAR, Kundan;PARAMANIK, Rajendra Narayan
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.6
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    • pp.109-116
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    • 2020
  • The study examines the nexus between financial development and economic growth in India during Q1: 1996 to Q3: 2018. This study employs time-series data of real GDP and ratio of broad money to GDP as a proxy for economic and financial development, respectively. The data are obtained from RBI database on the Indian economy. All variables are seasonally adjusted using X12-arima technique and expressed in natural logarithm form. Non-linear Autoregressive Distributed Lag (NARDL) bound test has been used to check for cointegrating relationship of these two variables. Empirical findings suggest that, unlike in the short run, in the long run financial development does impact economic growth positively. Further, a symmetric effect of positive and negative components of financial development is found for the Indian economy, whereas the effect of control variable like exchange rate and trade openness is in consonance with common economic intuition. Exchange rate is in consonance with intuitive economic logic that a fall in exchange rate makes exports cheaper and increases the quantity of export, which improves the balance of payment and leads to a rise in aggregate demand, hence improves economic growth. This paper contributes to the existing literature on India by breaking down financial indicator into positive and negative components to examine the finance-growth relationship.

A High-Isolation MIMO Antenna with Dual-Port Structure for 5G Mobile Phones

  • Yang, Hyung-kyu;Lee, Won-Woo;Rhee, Byung-Ho
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.4
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    • pp.1458-1470
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    • 2018
  • In this letter, a new dual-port Multiple-Input Multiple-Output (MIMO) antenna is introduced which has two independent signal feeding ports in a single antenna element to achieve smaller antenna volumes for the 5G mobile applications. The dual-port structure is implemented by adding a cross coupled semi-loop (CCSL) antenna as the secondary radiator to the ground short of inverted-F antenna (IFA). It is found that the port to port isolation is not deteriorated when an IFA and CCSL is combined to form a dual-port structure. The isolation property of the proposed antenna is compared with a polarization diversity based dual-port antenna proposed in the literature [9]. The operating frequency range is 3.3-4.0 GHz which is suitable for places where $4{\times}4$ MIMO systems are supposed to be deployed such as in China, EU, Korea and Japan at the band ${\times}$ (3.3 - 3.8GHz. The measured 6-dB impedance bandwidths of the proposed antennas are larger than 700 MHz with isolation between the feeding ports higher than 18 dB [1-2]. The simulation and measurement results show that the proposed antenna concept is a very promising alternative for 5G mobile applications.

A Case Study on a Woman's Shrounds in Middle of the 16th Century -Based on the Excavation of the Mrs. Moon's Grave in Andong Kyunbuk- (16세기 중엽 여성 염습의의 일례 -경북 안동시 정상동 일선문씨 분묘 출토복식을 중심으로-)

  • 이은주
    • Journal of the Korean Society of Costume
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    • v.48
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    • pp.151-168
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    • 1999
  • A Study on a Woman's Shrouds in Middle of the 16 Century based on the excavation of the Mrs. Moon's grave in Andong is reported in this paper. As a result of the study the followings are obtained: 1. From the architecture and costume in the Mrs. Moon's grave we can conclude that Confucian funeral rites were already established in Andong region of the 16th century. 2. The articles used for funeral rites can be classified as Bujangpum(副葬品) Chikwanjeku(治棺諸具) Bokongpoom(補空品), and Yumsupku(斂솝具) and costumes for the death wrapping can be especially classified as Yumsupeui(斂섭衣) 3. Total 63 remains were excavated from the Mrs. Moon's grave. Among them 3 Chikwanjeku 19 Daeryumku(大斂具) 12 Soryumku(小斂具) and 29 Supku(섭具) Yumsup procedure was performed with great care Shrouds were the casual cloths and only Sangbok were made for the ritual Several Sooeui were found. 4. Pricedyak characteristics of Yumsup include unusual direction of wrap the meaning of Boolryu and unusual Chingsoo of used clothes. 5. There were 41 costumes in : Coats were Sangbok and Jangot upper cloths were long jacket and short jacket Danjukori Jeoksam and Hansam Each of the trousers and the skirts were two different kinds by the form The pair of Hangjeon socks shoes and a cap found in this grave were also studied.

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Routing in Vehicular Ad Hoc Networks: Issues and Protocols

  • Shrestha, Raj K.;Moh, Sang-Man;Chung, Il-Yong
    • Korea Multimedia Society
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    • v.12 no.4
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    • pp.28-40
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    • 2008
  • Vehicular ad hoc networks (VANETs) are a practical application class of wireless ad hoc networks, which consist of moving vehicles equipped with radio communication capabilities that collaborate to form a temporary network. This paper addresses issues and protocols of multihop routing in such emerging networks in the context of safety and infotainment applications. Due to the highly dynamic mobility of vehicles, frequent link breakage and short connection time are inevitable and, thus, the routing is a challenging task and interest for many researchers and industrial community. The frequent and dynamic change of topology makes the topology-based routing unreliable but the position-based routing more effective. The position-based routing consists of the location service which maps a node id to a geo-graphical position and the forwarding scheme which selects the next hop based on geo-graphical information of the node, its neighbors and the destination. The routing techniques are further categorized into geographical forwarding, trajectory forwarding and opportunistic forwarding based on the forwarding scheme. In this paper, we first present the distinguished properties of VANETs and the challenges and intractable issues posed in designing the routing protocols, followed by the comprehensive survey of existing routing protocols. Then, the different routing protocols designed for VANETs are compared in terms of characteristics, performance and application domains.

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Apraxia of Phonation: a Case Report (발성실행증 사례연구)

  • Kwon, Mi-Seon;Na, Duk-L;Kim, Hyang-Hee;Jung, Jin-Sang
    • Speech Sciences
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    • v.12 no.2
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    • pp.101-108
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    • 2005
  • Apraxia of phonation (AOP) has often been described as a feature of apraxia of speech or of severe non-fluent type of aphasia. Pure AOP is rare and, to our knowledge, only two cases have been reported. Brain lesion sites of the reported cases were not those sites known to be responsible for apraxia of speech. This study presents a case of AOP which resulted from the secondary stroke in the left corona radiata immediately following the first stroke in the left temporoparietal lobe. A 61-year old right-handed man shwoed a global type of aphasia after the first cerebral infarction, but was able to generate spontaneously some short fragments of speech. On the day after the first infarction, he suffered from the secondary infarction, leaving him a complete loss of voluntary phonation. He did not showed any significant change in language functions. Several occurrences of involuntary phonation were observed upon laughing or crying. He was also able to cough unintentionally. A vidoe-stroboscopic examination failed to reveal any evidence of structural and functional impairment in larynx. Although this case is not of pure form of AOP, AOP appeared after the secondary stroke without significant changes of language impairment since the first stroke. Therefore, AOP may be a consequence of the brain lesion from the secondary stroke even though we cannot rule out the possibility of an additive effect of the secondary to the first stroke.

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