• Journal of Biomedical Engineering Research
• /
• v.18 no.2
• /
• pp.187-196
• /
• 1997

The three-dimensional flow analysis using the finite volume method is presented to compare the steady flow characteristics of blood with those of blood substitutes such as water and aqueous polymer solution in an idealized double branching model. The model is used to simlllate the region of the abdominal aorta near the celiac and superior mesenteric branches. Apparent viscosities of blood and the aqueous Separan solution are represented as a function of shear rate by the Carreau model, Water and aqueoiu Separan AP-273 500wppm solution are frequently used as blood substitutes in vitro experiments. Water is a typical Newtonian fluid and blood and Separan solution are non-Newtonian fluids. Flow phenomena such as velocity distribution, pressure variation and wall shear stress distribution of water, blood and polymer solution are quite different due to differences of the rheological characteristics of fluids. Flow phenomena of polymer solution are qualitatively similar to those of blood but the phenomena of water are quite different from those of blood and polymer solution. It is recommended that a lion-Newtonian fluid which exhibits very similar rheological behavior to blood be used in vitro experiments. A non-Newtonian fluid whose rheological characteristics are very similar to those of blood should be used to obtain the meaninylll hemodynamic data for blood flow in vitro experiment and by numerical analysis

• Journal of the Korean Geotechnical Society
• /
• v.22 no.11
• /
• pp.75-87
• /
• 2006

A series of calibration chamber tests are performed to investigate the spatial distribution of the excess porewater pressure due to piezocone penetration into overconsolidated clays. It was observed that the excess porewater pressure increases monotonically from the piezocone surface to the outer boundary of the shear zone and then decreases logarithmically, approaching zero at the outer boundary of the plastic zone. It was also found that the size of the shear zone decreases from approximately 2.2 to 1.5 times the cone radius with increasing OCR, while the plastic radius is about 11 times the piezocone radius, regardless of the OCR. Based on the modified Cam clay model and the cylindrical cavity expansion theory, the expressions to predict the Initial porewater pressure at the piezocone were developed, considering the effects of the strain rate and stress anisotropy. The method of predicting the spatial distribution of excess porewater pressure proposed in this study was verified by comparing it with the porewater pressure measured in overconsolidated specimens in the calibration chamber.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.7
• /
• pp.305-314
• /
• 2018

The steel-plate concrete composite beam is composed of a steel plate, concrete and a shear connector to combine the two inhomogeneous materials. In general, the steel plate is assembled by welding an existing composite beam. In this study, a new steel-plate concrete composite (SPCC) beam was developed to reduce the size of the shear connector and improve its workability. The SPCC beam was composed of folded steel plates and concrete, without any shear connector. The folded steel plate was assembled with high strength bolts instead of welding. To improve the workability in field construction, a hat-shaped cap was attached in the junction with the slab. Monotonic two-point load testing was conducted under displacement control mode. The flexural strength of the SPCC beam specimen was calculated to be 76% of that of the complete composite beam by using the plastic stress distribution method and strain compatibility method. The cap acted as the stud and accessory. The synthesis rate could be increased by controlling the gap of the cap, and the bending performance could be evaluated by using the strain fitting method considering the synthesis rate of the SPCC beam.

• Korea-Australia Rheology Journal
• /
• v.21 no.4
• /
• pp.269-280
• /
• 2009

The drop formation dynamics of a shear thinning, elastic, yield stress ($\tau_o$) fluid (Carbopol 980 (poly(acrylic acid)) dispersions) in silicone oil has been investigated in a flow-focusing microfluidic channel. The rheological character of each solution investigated varied from Netwonian-like through to highly non-Newtonian and was varied by changing the degree of neutralization along the poly (acrylic acid) backbone. We have observed that the drop size of these non-Newtonian fluids (regardless of the degree of neutralisation) showed bimodal behaviour. At first we observed increases in drop size with increasing viscosity ratio (viscosity ratio=viscosity of dispersed phase (DP)/viscosity of continuous phase (CP)) at low flowrates of the continuous phases, and thereafter, decreasing drop sizes as the flow rate of the CP increases past a critical value. Only at the onset of pinching and during the high extensional deformation during pinch-off of a drop are any differences in the non-Newtonian characteristics of these fluids, that is extents of shear thinning, elasticity and yield stress ($\tau_o$), apparent. Changes in these break-off dynamics resulted in the observed differences in the number and size distribution of secondary drops during pinch-off for both fluid classes, Newtonian-like and non-Newtonian fluids. In the case of the Newtonian-like drops, a secondary drop was generated by the onset of necking and breakup at both ends of the filament, akin to end-pinching behavior. This pinch-off behavior was observed to be unaffected by changes in viscosity ratio, over the range explored. Meanwhile, in the case of the non-Newtonian solutions, discrete differences in behaviour were observed, believed to be attributable to each of the non-Newtonian properties of shear thinning, elasticity and yield stress. The presence of a yield stress ($\tau_o$), when coupled with slow flow rates or low viscosities of the CP, reduced the drop size compared to the Newtonian-like Carbopol dispersions of much lower viscosity. The presence of shear thinning resulted in a rapid necking event post onset, a decrease in primary droplet size and, in some cases, an increase in the rate of drop production. The presence of elasticity during the extensional flow imposed by the necking event allowed for the extended maintenance of the filament, as observed previously for dilute solutions of linear polymers during drop break-up.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.12 no.1
• /
• pp.102-111
• /
• 2000

A numerical model which simulates the simultaneous heat and mass transfer within a vertical tube GAX absorber was developed. The ammonia vapor and the solution liquid are in counter-current flow, and the hydronic fluid flows counter to the solution liquid. The film thickness and the velocity distribution of the liquid film were obtained by matching the shear stress at the liquid-vapor interface. Two-dimensional diffusion and energy equations were solved in the liquid film to give the temperature and concentration, and a modified Colburn-Drew analysis was used for the vapor phase to determine the heat and mass fluxes at the liquid-vapor interface. The model was applied to a GAX absorber to investigate the absorption rates, temperature and concentration profiles, and mass flow rates of liquid and vapor phases. It was shown that the mass flux of water was negligible compared with that of ammonia except the region near the liquid inlet. Ammonia absorption rate increases rapidly near the liquid inlet and decrease slowly. Both the absorption rate of ammonia vapor and the desorption rate of water near the liquid inlet increase as the vapor mass flow rate increases, but the mass fluxes of the ammonia and the water near the liquid outlet decrease as the mass flow rate of the vapor increases.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2001.04a
• /
• pp.1016-1020
• /
• 2001

The spinning is a very effective manufacturing technology for short production runs in a variety of sizes and shapes, because it can form the cross-section or tubular parts various shapes. However extensive experimental and analytical research has not been carried out. In this study, and fundamental experiment was conducted to improve productivity with process parameter such as tool path, angle of roller holder(a), feed rate(v) and corner radius of forming roller(Rr). These factors were selected as variables in the experiment because they were most likely expected to have and effect on spring back. The clearance was controlled in order to achieve the precision product which is comparable to deep drawing one. And also thickness and diameter distribution of a multistage cup obtained by shear spinning process were observed and compared with those of a commercial product produced by conventional deep drawing.

• Journal of Microbiology and Biotechnology
• /
• v.31 no.6
• /
• pp.890-901
• /
• 2021

The 11α-hydroxylation of canrenone can be catalyzed by Aspergillus ochraceus in bioreactors, where the geometry of the impeller greatly influences the biotransformation. In this study, the effects of the blade number and impeller diameter of a Rushton turbine on the 11α-hydroxylation of canrenone were considered. The results of fermentation experiments using a 50 mm four-blade impeller showed that 3.40% and 11.43% increases in the conversion ratio were achieved by increasing the blade number and impeller diameter, respectively. However, with an impeller diameter of 60 mm, the conversion ratio with a six-blade impeller was 14.42% lower than that with a four-blade impeller. Data from cold model experiments with a large-diameter six-blade impeller indicated that the serious leakage of inclusions and a 22.08% enzyme activity retention led to a low conversion ratio. Numerical simulations suggested that there was good gas distribution and high fluid flow velocity when the fluid was stirred by large-diameter impellers, resulting in a high dissolved oxygen content and good bulk circulation, which positively affected hyphal growth and metabolism. However, a large-diameter six-blade impeller created overly high shear compared to a large-diameter four-blade impeller, thereby decreasing the conversion ratio. The average shear rates of the former and latter cases were 43.25 s^-1 and 35.31 s^-1, respectively. We therefore concluded that appropriate shear should be applied in the 11α-hydroxylation of canrenone. Overall, this study provides basic data for the scaled-up production of 11α-hydroxycanrenone.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2004.10a
• /
• pp.54-57
• /
• 2004

Almost all injection molds have multi-cavity runner for mass production, which are designed with geometrically balanced runner system in order to minimize filling imbalance between cavity to cavity during processing. However, even though geometrically balanced runner is used, filling imbalances have sometimes been observed. These filling imbalances have historically been considered as result of uneven mold temperature and mold deflection, but it actually results from non-symmetrically shear, pressure, temperature distribution within melt material as it flows through the runner system. Filling imbalance could be decreased by modifying processing conditions that are related to shear, pressure, temperature such as injection rate, mold temperature, injection pressure, melt temperature. In this study, a series of experiment was conducted using Taguchi method to determine which processing condition influence as the primary cause of filling imbalance in geometrically balanced runner system. As a result of experiments, this paper could present an optimal processing condition to minimize variable that brings about filling imbalance geometrically balanced runner system

• Journal of Powder Materials
• /
• v.13 no.2 s.55
• /
• pp.124-128
• /
• 2006

In recent years, equal channel angular pressing (ECAP) has been the subject of intensive study due to its capability of producing fully dense samples having a ultrafine grain size. In this paper, the ECAP process was applied to metallic powders in order to achieve both powder consolidation and grain refinement. In the ECAP process for solid and powder metals, knowledge of the internal stress, strain and strain rate distribution is fundamental to the determination of the optimum process conditions for a given material. The properties of the ECAP processed solid and powder materials are strongly dependent on the shear plastic deformation behavior during ECAP, which is controlled mainly by die geometry, material properties, and process conditions. In this study, we investigated the consolidation, plastic deformation and microstructure evolution behaviour of the powder compact during ECAP.

• Journal of Biomedical Engineering Research
• /
• v.17 no.1
• /
• pp.49-60
• /
• 1996

An experimental investigation was performed under steady flow condition to assess hydrodynamic performance of floating-type monoleaflet polymer valves (MLPV) withdifferent leaflet thickness. The St. Jude Medical valve (SJMV) was also used for comparison test. Pressure drops of MLPVS are larger than those for other types of polymer valves and mechanical valves. Furthermore, the thicker is the leaflet thickness of the polymer valve, the larger are the corresponding pressure drop. The velocity profiles for MLPs reveal a large reversed flow region downward to the valve position. The maximum wall shear stresses of MLPVS at a flow rate of $30{\ell}$/min are in the range 50-130 dyn/$cm^2$, and the corresponding maximum Reynolds shear stresses are in the range of 100-500 dyn/$cm^2$, respectively, which are beyond the allowable limit clinically. In contrast, floating-type monoleaflet polymer valves show better hydrodynamic performance in leakage volume. From the designing point of view, it may be concluded that the optimum thickness of leaflet for better hydrodynamic performance is one of the Important parameters.