• 한국버섯학회지
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• 제17권4호
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• pp.211-217
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• 2019

최근 ICT기반 스마트팜이 급속도로 증가추세이다. 버섯의 생육환경요인은 온도, 습도, CO₂, 광이 주 요인이지만 그동안 온도 위주의 자동제어가 사용되어왔다. 큰느타리버섯의 생육환경 조절은 온도는 자동제어하지만 가습과 환기는 경험을 기준으로 한 타이머 사용을 하고 있었다. 이에 본 연구에서는 온도, 습도, 환기까지 자동제어를 통해 큰느타리버섯의 1세대 스마트팜 모델을 설정하기 위한 시험을 진행하였다. 환경제어시스템 및 모니터링 장비를 설치 한 후 기존의 방법으로 재배하고 있는 상태에서 생육실의 조건과 자실체의 생육조사를 실시하였으며 그 결과를 소개하고자 한다. A농가의 경우 온도는 약 17℃에서 발이시키고 자실체 생육기에는 약 16도로 관리하였다. 습도는 초기 95%로 유지하다가 초발이 이후에는 가습을 하지 않는 경향이었다. CO₂ 관리는 센서도 없었으며 갓과 대의 모양을 보면서 관행적으로 환기하고 있었고 700 ppm에서 최고 2,500 ppm까지 유지하는 경향이었다. 이 농가의 자실체 품질은 평균 개체중 125 g, 대굵기 53 mm, 대길이/대굵기 비율은 1.8, 갓직경/대굵기 1.25 수준으로 A등급(특품)~B등급(상품) 사이에 해당하였다. B농가의 경우는 온도는 약 19~17℃에서 발이시키고 자실체 생육기에는 약 17℃로 관리하였고 생육후기에는 13~15℃였다. 습도는 83~95%로 육안관찰하면서 관행적으로 조절하는 경향이었다. CO₂ 관리는 센서는 있었으나 제어는 하지 않았고 갓과 대의 모양을 보면서 관행적으로 환기하고 있었고 640 ppm에서 최고 4,500 ppm까지 유지하는 경향이었다. 이 농가의 자실체 형태는 평균 개체중 102 g, 대굵기 48 mm, 대길이/대굵기 비율은 2.2, 갓직경/대굵기 1.2 수준이었다. 이러한 결과는 환경조건 특히 CO₂ 농도에 따라 큰느타리버섯의 품질이 결정됨을 알 수 있었으며 A농가의 환경조절 방법을 개선하면서 DB화하면 정밀한 스마트팜 모델로 적용할 수 있을 것으로 기대된다.

• 한국소음진동공학회논문집
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• 제25권1호
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• pp.48-57
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• 2015

제 4세대 원자로로 개발되고 있는 소듐냉각고속로는 냉각재로 사용되는 소듐의 물과 공기에 의한 반응을 방지하기 위하여 원자로 헤드의 개방 없이 회전 구동만을 이용하여 핵연료 교환을 수행한다. 따라서 핵연료 교환을 위해서는 노심과 상부내부구조물 사이의 공간에 원자로 헤드의 회전 구동을 방해하는 장애물의 존재 여부를 확인하는 검사가 반드시 선행되어야 하는데, 소듐의 불투명성으로 인해 통상적인 광학 장비를 사용한 검사방법으로는 장애물의 확인이 어렵고, 초음파를 이용한 검사방법이 적용되어야 한다. 이 연구에서는 불투명한 소듐 중에서 노심과 상부내부구조물 사이의 장애물 존재 여부를 확인하기 위하여 판형 웨이브가이드 초음파 센서를 적용한 원격주사 검사기법을 개발하였다. 웨이브가이드 센서는 원자로헤드 상부의 저온 구간에 초음파 트랜스듀서를 설치하고 길이가 긴 웨이브가이드를 사용하여 노심 상부의 고온 고방사능 소듐 내부로 초음파를 전파시키기 때문에, 고온 고방사능에 의한 손상 없이 장시간 적용이 가능한 장점을 가지고 있다. 먼저, 수평 방향으로 초음파를 방사시킬 수 있는 10 m 길이의 수평 빔 웨이브가이드 센서를 설계 제작하였고, 제작된 센서의 특성 분석을 위한 빔 프로파일 측정 및 기초 실험을 수행하여 방사되는 초음파의 빔 폭과 전파 거리를 평가하였다. 또한, 실제 장애물로 작용할 수 있는 부품들의 형상인 원형 목표물에 대한 원격탐지 성능시험을 수행하여 개발된 원격주사 기술의 유용성을 평가하였다.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2007년도 추계 종합학술대회 논문집
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• pp.560-564
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• 2007

한국기초과학지원연구원(KBSI, Korea Basic Science Institute)에서는 국내 유일의 초고전압투과전자현미경(HVEM, High Voltage Electron Microscopy)을 비롯하여 3 대의 일반 전자현미경을 보유하고 있다. 전자현미경을 통하여 관찰된 이미지는 각 단계별로 tilting 되어 저장된 이미지로서 관찰자에게 보다 나은 관찰 환경의 구성을 위해 3D로의 reconstruction은 필수 과정이라고 할 수 있겠다. 이 과정 중 카메라 중심에서 벋어난 부분의 왜곡을 warping 기법을 통하여 최대한 감소시킨다. 이런 이미지 전처리 과정과 이를 바탕으로 3D로의 reconstruction과정은 고성능 컴퓨터의 수반을 기본으로 하는데 이 과정을 다수의 grid node PC들이 빠른 시간에 분담하여 처리하게 된다. Grid node PC들의 역할은 소유자가 서로 다른 다양한 컴퓨팅 자원의 효과적인 공유를 목적으로 하며, 시스템의 구축에 필요한 역할 스케줄링, 자원 관리, 보안, 성능 측정 및 상태 모니터링 등의 문제를 해결하기 위한 사용되고 있다. 일반 개인이 사용하기 힘들었던 고성능 PC의 역할을 Grid node PC들이 수행하고 이 기반위에 워핑 기법을 통한 이미지 전처리는 보다 실제 관찰 대상에 가까운 형태로의 재구성이 가능할 수 있는 바탕이 된다. 워핑 전처리를 통한 Grid node PC기반의 전자현미경 볼륨 랜더링 시스템의 구축은 관찰자에게 보다 편리하며 빠른 실험 환경을 제공하여 줄 수 있고, 이해하기 쉽고 실제 모습에 가까운 형태의 실험 결과물을 접할 수 있게 된다.

• 지적과 국토정보
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• 제47권1호
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• pp.161-178
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• 2017

한국 국토의 60% 이상을 차지하고 있는 산림지역에 대한 개발과 이용의 수요가 증가하고 있지만, 개발사업의 허가는 산림생태계의 보전보다는 국토 이용 중심의 평가로 이루어지고 있다. 대규모 산림지역을 평가할 경우 산림의 구조를 중심으로 분석하기 때문에 산림 내부의 변화를 관찰하고 분석하는데 한계가 있다. 따라서 본 연구에서는 충청남도 식생군락의 현존식생도와 FRAGSTATS 4.2를 이용하여 경관지수를 산출하고 식생 모자이크를 분석해 보았다. 식생 군락은 주요 자생 수종을 중심으로 대표군락과 세부군락으로 구분하였고, 군락별 차이를 분석하기 위해 분포면적(CA), 분포면적비율(PLAND), 패치개수(NP) 등의 10가지 경관지수가 선택되었다. 충청남도 식생의 대표군락과 세부군락은 소나무군락, 상수리나무군락 및 소나무와 참나무류 수종의 조합이 우세하게 나타났으며, 소나무군락의 면적이 상당히 높게 나타났다. 소나무군락과 참나무류군락의 경쟁의 경우, 대표군락의 경우 소나무군락이 전체 분포면적은 3배 가량 넓으나 작은 패치로 나뉘어져 모자이크화 정도는 참나무류 군락이 작은 것으로 판단되었다. 세부군락의 경우에는 소나무 중심의 군락에서는 소나무-신갈나무군락이, 상수리나무 중심 군락에서는 상수리나무군락이, 굴참나무 중심의 군락에서는 굴참나무-소나무군락이, 신갈나무 중심의 군락에서는 신갈나무군락이, 곰솔 중심의 군락에서는 곰솔군락이, 졸참나무 중심의 군락에서는 졸참나무-상수리나무군락이 넓은 분포면적과 동시에 모자이크화도 심한 것으로 나타났다. 전체적인 모자이크화 양상은 수치로 표현될 수 있어 모니터링 단계에서 문제가 있는 식생군락을 판별할 때 유용할 것으로 판단되었다. 모자이크화의 원인과 천이의 방향성 예측을 통한 관리 방안 마련을 위해서는 각 군락의 생태적인 특성에 대한 연구가 추가적으로 필요할 것으로 판단되었다.

• 한국환경생태학회지
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• 제27권6호
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• pp.676-689
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• 2013

본 연구는 강원도 원주시에 도심지를 통과하는 원주천과 외곽의 국가하천인 섬강 전 구간을 조사하여 비오톱유형화를 통해 하천 자연생태 현황을 파악하고, 야생조류 출현위치를 파악하여 비오톱과 야생조류 출현현황의 관계를 분석하였다. 비오톱유형은 규모, 형태, 경관에 따라 중분류하였으며, 수문, 물리환경, 식생에 따라 소분류하였다. 또한 하천공간, 물리환경, 식생, 토지이용에 따라 비오톱유형을 세분류하였으며, 조사 결과 섬강은 21개 유형, 원주천은 19개 유형으로 분류하였다. 야생조류는 2008년 1월과 5월에 조사를 시행하였으며, 각 조류의 출현위치를 표기하여 야생조류 출현지점의 비오톱 속성을 파악하였다. 야생조류 출현 현황은 섬강 전 구간에서 봄철 31종 795개체, 겨울철 49종 4,348개체이었고, 원주천에서는 봄철 34종 427개체, 겨울철 33종 3,442개체이었다. 섬강은 산지형 하천 중 합수부 퇴적지 자연하천 지역에 겨울철 26종 547개체, 봄철 12종 72개체이었으며, 농촌형 하천 중 퇴적지 및 습지식생이 넓게 형성된 자연하천 지역에 겨울철 34종 1,412개체, 봄철 24종 341개체이었다. 이에 농촌형 하천은 하폭이 넓고 유속이 느리며, 다양한 비오톱유형이 있어 야생조류 서식에 양호한 것으로 판단되었다. 본 연구에서는 조사와 표현이 힘든 선형 하천구간에 정밀 비오톱 조사와 유형화를 통해 하천 전체 현황을 파악하였으며, 야생조류 출현현황을 조사하여 생물서식처 복원, 생태하천 조성, 하천정비 등의 기초자료로 활용되며, 원주시 도심 생물다양성 증진을 위한 자료로 활용 가능하다. 또한 하천은 강우에 의해 비오톱 속성이 빈번하게 변경되므로 지속적인 모니터링을 통해 하천생태계가 유지될 수 있도록 관리해야 할 것이다.

• 생태와환경
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• 제39권2호통권116호
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• pp.271-283
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• 2006

섬 지역의 초기 담수과정에 있는 상수원 저수지 (절곡저수지)에서 수색 악화와 여과지 폐색의 원인을 분석하기 위해 2005년 8월에 식물플랑크톤을 포함한 다각적인 수환경 조사를 수행하였다. 저수지의 형태는 단순하였고, 평균 수심은 5.5 m로서, 상류에서 얕고 댐 부근에서 가장 깊었다. 환경요인 중에서 수평적 또는 수직적 차이가 큰 인자는 DO, Chl-a이었고,가장 작은 인자는 수온이었다. 수중 투명도는 0.6 ${\sim}$ 0.9 m범위(평균값 0.7 m)이었고, 탁도의 평균값은 9.3 NTU (8.0 ${\sim}$ l2.1 NTU범위)이었다. 후명도와 탁도의 증감요인은 생물 또는 비생물의 복한적인 영향으로 달 수 있었고 공간적인 차이도 탄영되었다. 수색이 탁한 것은 무기입자의 증가와 식물플랑크톤치 과대증식 영향이 주된 원인이었고, 여과지 폐색은 저수지로부터 식물플랑크톤의 과잉 공급에 의한 문제점이었다. 저수지 내 chlorophyll-a농도의 범위와 평균값은 상층에서 31.6 ${\sim}$ 258.9 ${\mu}g\;L^{-1}$, 123.6 ${\mu}g\;L^{-1}$, 저층에서 17.0 ${\sim}$ 37.4 ${\sim}$, 26.5 ${\sim}$이었다. Chlorophyll-a의 증가는 담수적조의 대발생 영향이었고, 주종은 와편모조류 Peridinium bipes f. occultatum이었다. Peridinium의 분포는 chlorophyll-a농도와 밀접한 관련성이 있었다. 담수적조의 현존량은 상류지역에서 $8.5\;{\times}\;10^3\;cell\;mL^L{-1}$로서 많았고, 댐부근의 하류지역($4.4\;{\times}\;10^2\;cell\;mL^L{-1}$)으로 갈수록 감소하는 양상을 보였다. 또한, 담수적조의 원인종으로 규조류 Synedra acus와 남조류 Microcystis aeruginosa도 소량관찰되었다. 저수지의 수질 부영양화 현상은 기존 경사사면형 농경지를 기반으로 조성되었으므로 저층으로부터 풍부한 영양환경을 내재하고 있었고, 담수 초기에 발생할 수 있는 가능성을 포함하고 있었다. 또한 유입수량의 부족과 현재 수질개선을 위해 적용하고 있는 수중폭기시설등의 물리적인 영향도 직 ${\cdot}$ 간접적으로 작용하였을 것으로 추정되었다 따라서 향후 이에 대한 중장기적인 모니터링이 필요하였고 유역과 저수지의 통합적인 수질관리계획 이 요구되었다.

• 한국전통조경학회지
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• 제32권2호
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• pp.68-81
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• 2014

본 연구는 제주시 한림읍 소재 명월대와 명월숲의 생태문화경관적 특성 파악과 가치 발굴을 목적으로 시도되었다. 이를 위해 이곳의 장소성을 밝히고 명월대와 명월숲의 경관특성을 조명하는 한편 지속가능한 활용과 보존을 위한 관리방안을 제시하였다. 본 연구의 주요 결과는 다음과 같다. 명월성과 명월포구는 예로부터 군사요새이자, 명월 수류촌은 서부 제주지역 행정의 중심지인 한림읍 명월지역의 위상을 보여줄 뿐 아니라 명월지역에 존재했던 월계정사와 우학당은 교육문화의 본산으로, 교육 중심지 명월리의 장소성을 대변한다. 명월대는 조선시대 선비들이 시와 풍월을 즐기고, 장기와 바둑을 두던 유풍이 남아있는 음풍농월의 현장이자 제주도의 대표적인 유교 문화경관이다. 현재의 명월대 유구는 일제강점기인 1931년 홍종시(洪鍾時)를 중심으로 한 명월청년회 주도로 이루어진 정비사업의 결과이다. 사각형-팔각형-원형 등 3단으로 구성된 명월대의 석축 구성은 유교사상의 천인합일사상을 바탕으로, 중앙의 팔각은 천원지방(天圓地方)의 의미를 부여한 것으로 보인다. 한편 명월대교와 명월교는 모두 초기에는 홍예교로 석축된 것으로 추정되며 명월교는 제주에 남아있는 유일한 홍예교로 근대문화유산적 가치가 있다. 명월숲의 식물상은 총 97분류군(taxa)이 확인되었으며, '식물구계학적 특정식물종의 분류군 및 등급기준'에 준하면 IV등급에는 가는쇠고사리, III등급에 호랑가시나무, 후추등, 까마귀쪽나무, 멀구슬나무, 산유자나무, 노랑하늘타리, 아욱메풀, 아왜나무 등 8분류군으로 나타났다. 반면에 귀화식물은 제주도에만 이입된 솔잎미나리를 비롯하여 14분류군이 확인되었다. 명월숲에는 팽나무 41주와 푸조나무 30주, 산유자나무 2주, 소나무, 동백나무, 멀구슬나무, 호랑가시나무 각각 1주 등 도합 77그루의 수목이 군락을 이루고 있다. 조사된 자료를 근거로 명월대와 명월숲의 보존관리방안은 다음과 같다. 명월대와 명월교 그리고 명월숲을 하나의 통합 영역으로 한 보존관리가 필수적이다. 명월교는 제주도내에서는 찾아보기 어려운 홍예교로 수준 높은 석공예물로 장기적인 보존방안이 마련되어야 할 것이다. 한편 교량노후화로 인해 사고위험에 노출되고, 안전진단이 요구되는 명월대교는 정밀안전진단 결과에 따른 대책이 요구된다. 재시공시 초건 시의 모습인 2수문의 완벽한 홍예교로 건립하여 명월대와 함께 향후 대표적 지역 명소로 보존 및 활용해야 할 것을 건의한다. 또한 조사결과에 근거한 종조성으로 볼 때 현재 제주특별자치도 기념물 제19호 '명월 팽나무군락'의 명칭은 '명월 팽나무-푸조나무군락'으로 재고되어야 할 것이다. 그리고 팽나무와 푸조나무 구분 없이 이루어진 일련번호 체계는 개선되어야 하며 노거수목 및 특정식물종이나 귀화종에 대해서는 생육상태에 대한 주기적인 모니터링이 요구된다.

• 한국식품영양과학회지
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• 제34권2호
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• pp.202-208
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• 2005

본 연구에서는 청소년기 남녀 중학생의 건강과 관련된 임상 증상에 따른 식습관, 영양지식, 영양태도를 알아보기 위하여 조사를 실시하였다. 좋지 않은 건강상태를 나타내는 임상증상 중 자주 생긴다고 답한 항목이 1개 이하인 경우를 건강군, 2개 이상의 항목에서 자주 생긴다고 답한 경우를 비건강군으로 분류하여 각 조사 항목을 비교 분석한 결과를 요약하면 다음과 같다. 전체 대상자들(524명)의 평균 연령은 14.0세였으며, 신장은 남학생 162.0 cm, 여학생 157.2 cm였고, 체중은 남학생 53.4 kg, 여 학생 49.4 kg으로 신장과 체중 모두 남학생이 높았다. 신장과 체중으로부터 산출한 체질량지수(BMI)는 남학생 20.3 kg/$m^2$, 여학생 20.0 kg/$m^2$로 모두 정상 범위에 속하였다. 건강군(289명)과 비건강군(235명)의 평균 연령, 체중, 신장, 체질량지수는 유의적인 차이를 보이지 않았다. 체형 인식, 만족도, 체중조절 시도여부를 비교한 결과 본인의 체형에 대한 인식은 건강군과 비건강군 간에서 유의적인 차이를 보이지 않았으나, 체형만족도에서는 유의적인 차이를 보여 본인의 체형에 만족하지 않는다는 비율이 건강군 여자의 33.1%에 비하여 비건강군 여자는 46.2%로 높게 나타났다(p<0.05). 지난 1년간의 체중조절 시도 여부에 대하여서도 비건강군 여자의 59.5%가 체중을 감소시키기 위하여 노력하였다고 답하여 건강군 여자의 38.5%에 비하여 유의적으로 높았다(p<0.01). 남학생의 경우에는 체형만족도와 체중 조절 경험에 있어서 두 군간 유의한 차이를 보이지 않았다. 영양지식과 영양태도 점수를 비교한 결과 건강군과 비건강군간에 유의적인 차이를 보이지 않았다. 끼니별 식사빈도를 조사한 결과 여자의 경우 아침식사를 주4회 이하로 하는 경우가 건강군은 30.7%였으나, 비건강군의 경우 44.0%로 높았다(p<0.05). 저녁 식사는 주 4회 이하의 식사를 하는 경우가 건강군은 10.7%인 반면, 비건강군은 18.8%로 아침 과 저녁 식사 모두 여자 비건강군의 결식률이 유의적으로 높게 나타났다(p<0.01).외식빈도는 남자의 경우 주 3회 이상에서 비건강군이 56.5%로 건강군의 42.7%보다 유의적으로 높았으며, 간식빈도는 여자의 경우 건강군에 비하여 비건강군이 유의적으로 높았다(p<0.05).식사의 구성을 조사한 결과 유의적인 차이를 보이지는 않았으나 비건강군이 건강군에 비하여 세 끼 식사의 구성이 불량하다고 답한 비율이 높은 경향을 나타내었다. 본 연구 결과를 통하여 건강의 이상 여부를 반영하는 임상증상의 빈도가 높은 청소년기 남녀 중학생의 경우 아침과 저녁의 결식빈도 및 외식과 간식의 빈도가 높았고, 아침식사의 질과 체형만족도가 낮은 것으로 나타나 청소년의 건강과 식습관 및 체형만족도가 상호 관련성이 높은 것으로 나타났다. 따라서 본 연구 결과는 성장기 청소년의 건강 유지를 위하여 바람직한 식습관의 중요성을 재인식할 수 있었으며, 올바른 식습관 확립을 위한 영양교육의 중요성이 재확인되었다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.