• The Journal of Korean Society for School & Community Health Education
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• v.13 no.2
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• pp.77-91
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• 2012

배경 및 목적: 성병 감염, 조기 성경험, 다수의 성관계 파트너 등과 같은 위험 성행동은 여성의 건강 전반을 위협하는 결과를 초래할 수 있다. 하지만, 이러한 심각성에 비하여, 미국의 청소년기 및 청년기 여성의 위험 성행동을 소수인종 집단별 특성을 고려한 연구는 부족한 실정이다. 그러므로 본 연구는 미국 소수인종 여성 청소년의 위험 성행동에 대한 실태를 조사하고자 한다. 방법: 본 연구는 2차 자료 분석의 결과물로써, 원자료인 미국의 National Longitudinal Study of Adolescent Health (Add Health)의 1기 (1995년)와 3기 (2001년)의 자료 중 여성 청소년의 자료를 바탕으로 분석되었다. 다양한 위험 성행동을 인종별로 분석함과 더불어 본 연구의 특징은 종단적 성병 감염 행태를 인종별로 분석한 점이다. 결과: 본 연구는 소수인종 여성의 위험 성행동에 관한 핵심적인 결과를 제시한다. 성병 감염, 조기 성경험, 다수의 성관계 파트너 등과 같은 위험 성행동의 분포는 흑인과 아시아계 여성이 타인종의 여성에 비하여 높은 위험해 쳐해 있는 것으로 나타났다. 본 연구의 흑인 여성들은 전반적인 성행동을 망라하여 고위험군으로 분류되고 있다. 아시아계 여성 역시 고위험 군으로 분류되는데, 특히, 청소년기에 성병에 한번 감염된 경험이 있는 아시아계 여성은 가장 위험한 성병 감염 행태를 보이고 있는 것으로 나타났다. 결론: 본 연구의 결과는 소수인종 여성의 위험 성행동이 백인보다 전반적으로 높은 편으로 나타나지만, 적절한 보건의료 서비스에서는 소외되는 현실을 지적하고 있다. 이러한 인종별 성건강의 불균형 문제해소를 위하여 청소년들에게 인종적 특성과 서비스 접근성의 고려가 절실히 필요하다고 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3305-3308
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• 2013

Background: The role of inflammation in prostate diseases is suggested by the presence of inflammatory cells within the prostate in benign prostatic hyperplasia (BPH) and prostate cancer (PCa) patients. In addition, bacterial and viral infection may lead to chronic and recurrent inflammation of the prostate. The human papillomaviruses (HPVs) are a family of sexually transmitted viruses which have been implicated in the aetiology of cervical cancer and several other malignancies. This study evaluated the frequency of HPV infection in individuals with prostatic disease in Iran. Materials and Methods: The study included formalin fixed paraffin- embedded tissue samples of 196 primary prostate cases, including 29 PCa and 167 BPH samples. HPV DNA was purified and amplified through MY09/MY11 and GP5+/GP6+ primers with nested PCR. All patients were interviewed using a questionnaire to collect demographic information. Results: Nested PCR showed that HPV DNA was found in 17.2 percent of PCa samples and 4.8 percent of BPH samples (not significant). Conclusions: Our data do not support a significant role of HPV infection in prostatic disease in Iranian patients, but demographic data indicated a probable association between presence of HPV DNA and risk of inflammation in prostate tissue which might lead to prostate carcinoma. Further studies are required to elucidate any roles of HPV infection in prostatic disease.

• Child Health Nursing Research
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• v.8 no.3
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• pp.313-321
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• 2002

We would like to suggest the guideline of use of materials of sexual education for adolescent in school by examining the status of use of materials and by evaluating the video materials frequently used. Survey was done by enquetes on status of use of materials of sexual education from school nurses in 190 primary, 44 middle and 50 high schools in Seoul, Kyonggi-do and Kangwon-do from August 1999 to February 2000. The frequently used 84 videotapes were evaluated on their contents. As for the status of use, 99.3% of subjected schools possessed the materials for sexual education. Decision of purchase was determined according to the review of contents (92.6%). Information about materials was received by the advertisement in newspapers or broadcasting (46.1%) or recommendation of peer teacher (32.4%). Videotape was most frequently used (64.1%) rather than books or CD. Teachers concerns on the materials were the educational content according to developmental stage of students (41.9%), content provoking interest (33.5%) and concrete guide for teacher (10.6%). As for the evaluation of the contents of videotapes, a subject of education was not described out of 46.6%. Videotape producer were mostly the Government-affiliated institutes or non-profit organizations (86.8%). The year of production was indicated from 41.7%. Running time range of 21-30 minutes was highest (55.9%). The price was marked in only one videotape. Subjects of contents were general sexual education (34.5%), sexual violence or sexual harassment (21.4%), pregnancy and contraception (14.2%) and AIDS and sexually transmitted diseases (8.3%) and dating and adolescent change (4. 8%), and etc (11.9 %). According to above results, we suggested that materials for sexual education should be completed with a description on the subjected group, summary of content, information on the tape producer, year of production, running time and sale price.

• Parasites, Hosts and Diseases
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• v.57 no.1
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• pp.21-25
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• 2019

Trichomoniasis is the most common curable sexually-transmitted infection. Most Trichomonas vaginalis-infected men are asymptomatic and can remain undiagnosed and untreated, and this has been thought to result in chronic persistent prostatic infection. Chronic inflammation is regarded as the major factor in the pathogenesis and progression of benign prostatic hyperplasia (BPH) and prostatic cancer (PCa). The aim of this study is to identify seropositivity to T. vaginalis in men with prostate tumors (BPH or PCa) visited to Hanyang University Hospital. A total of 183 men were enrolled between October 2013 and November 2014. They consisted of 139 with BPH (mean age: $64.0{\pm}0.07$) and 44 with prostate cancer (mean age: $73.3{\pm}0.18$). We carried out ELISA to identify the seropositivity to T. vaginalis. Mixed lysate antigen extracted from 8 strains of T. vaginalis was used in the ELISA. Also 58 male outpatients visited to Health Promotion Center in Hanyang University Hospital were evaluated for comparing group. As a results, seropositivity to T. vaginalis in patients with prostatic diseases was 19.7% (BPH: 18.7%, PCa: 22.7%) and it was significantly higher than the 1.7% of the comparing healthy group (P=0.001). Therefore, prostatic tumor showed higher seropositivity against T. vaginalis than normal men. As far as we know, this is the first report about seroprevalence in prostatic tumor in Korea.

• The Journal of Korean Society for School & Community Health Education
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• v.22 no.1
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• pp.37-53
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• 2021

Background and objectives: Human papillomavirus (HPV) is the most common sexually transmitted infection globally and is responsible for multiple clinical outcomes, including genital warts and cervical, anal, and oropharyngeal cancers. Despite the well established burden of HPV on both men and women, vaccine uptake among men is critically low in Korea. A preliminary step to combat this issue is to target parents of male adolescents. In the present study, we aimed to assess any change observed in parents' HPV knowledge and attitudes towards male HPV and subsequent willingness to vaccinate their sons following an HPV educational intervention. Methods: On November 14, 2020, a one-time HPV educational session was conducted and parents (n=136) completed self-administered pre-/post-test questionnaires that included previously validated survey items. Paired t-tests were used to evaluate change in HPV-related knowledge, attitudes and intent for HPV vaccination. Results: Following the intervention, participants reported increased scores in HPV and vaccine related knowledge by approximately 4 and 1.5 points, respectively (p<.001). Parents scored higher on perceived benefits of the vaccine, perceived social influence on vaccination decision and perceived severity of diseases caused by HPV infections, whereas lower scores were observed for perceived harm of the vaccine, and difficulties communicating with their sons about sex and HPV vaccination. Following the intervention, those without the intent to vaccinate their sons significantly decreased and those who intended to vaccinate their sons though not in the next six months significantly increased (χ2=33.045, p<.001) Conclusion: Our educational intervention resulted in an increase in HPV-related knowledge with a positive impact on parents' attitudes toward male HPV vaccination. We expect that this study can serve as a pivotal reference to promote the unexplored issue of HPV vaccination among male adolescents in Korea.

• Parasites, Hosts and Diseases
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• v.62 no.3
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• pp.270-280
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• 2024

Trichomoniasis is caused by a sexually transmitted flagellate protozoan parasite Trichomonas vaginalis. T. vaginalis-derived secretory products (TvSP) contain lipid mediators such as leukotriene B₄ (LTB₄) and various cysteinyl leukotrienes (CysLTs) which included LTC₄, LTD₄, and LTE₄. However, the signaling mechanisms by which T. vaginalis-induced CysLTs stimulate interleukin (IL)-8 production in human mast cells remain unclear. In this study, we investigated these mechanisms in human mast cells (HMC-1). Stimulation with TvSP resulted in increased intracellular reactive oxygen species (ROS) generation and NADPH oxidase 2 (NOX2) activation compared to unstimulated cells. Pre-treatment with NOX2 inhibitors such as diphenyleneiodonium chloride (DPI) or apocynin significantly reduced ROS production in TvSP-stimulated HMC-1 cells. Additionally, TvSP stimulation increased NOX2 protein expression and the translocation of p47^phox from the cytosol to the membrane. Pretreatment of HMC-1 cells with PI3K or PKC inhibitors reduced TvSP-induced p47^phox translocation and ROS generation. Furthermore, NOX2 inhibitors or NOX2 siRNA prevented CREB phosphorylation and IL-8 gene expression or protein secretion induced by TvSP. Pretreatment with a CysLTR antagonist significantly inhibited TvSP-induced ROS production, CREB phosphorylation, and IL-8 production. These results indicate that CysLT-mediated activation of NOX2 plays a crucial role in ROS-dependent IL-8 production in human mast cells stimulated by T. vaginalis-secreted CysLTs. These findings enhance our understanding of the inflammatory response in trichomoniasis and may inform the development of targeted therapies to mitigate this response.

• Korean Journal of Health Education and Promotion
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• v.19 no.3
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• pp.51-72
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• 2002

This research was conducted to understand and analyze the health-related behaviors of middle school students and get fundamental research data essential to provide efficient student guidance and public health service at school. The interview using Youth Risk Behavior Surveillance System(YRBSS). Translation and modification for Korean students of the YRBS. The Korean version of YRBS(Youth Risk Behavior Surveillance System) that translation and modification for Korean students of the YRBS developed by the Centers for Disease Control and Prevention(CDC)was used to assessment to health-related behaviors of youth. The interviewees were 1040 enrolled students at middle school in Daegu metropolitan city. YRBSS monitors six categories of priority health behaviors among youth and young adults behaviors that contribute to unintentional and intentional injuries; tobacco use; alcohol and other drug use, sexual behaviors that contribute to unintended pregnancy and sexually transmitted diseases(STDs)(including human immunodeficiency virus infection); unhealthy dietary behaviors; and physical activity. The result shows that over 30% of students rarely or never used safety belt and almost students were rarely or never wore a bicycle helmet. During the 12 months preceding the survey, 21.9% female students had felt so sad or hopeless almost every day for $\geq$ 2weeks in a row that they stopped doing some usually activities 20.5% of male middle school students have ever tried cigarette smoking. 26.2% of male students and 27.2% do female students had had over one drinks of alcohol during their lifetime(lifetime alcohol use). 47% of male students had had over one drinks of alcohol on $\geq$ 1 of the 30 days preceding the survey(current alcohol use). Over one half of female student were thought they were overweight. These results suggest that some risk behaviors be very prevalent in a korean middle school students and priority health-risk behaviors, which contribute to the leading cause of mortality and morbidity among youth and adult, often are establish during middle school age, extend into adulthood, are interrelated. Among both children and adults, the leading causes of death are closely linked to these behaviors. Among adults, chronic diseases such as cardiovascular disease, cancer, and diabetes are the national leading killers. Practicing healthy behaviors, such as eating low-fat, high-fruit-and-vegetable diets, getting regular physical activity, and refraining from tobacco use, would prevent many premature deaths. Because health-related behaviors are usually established in childhood, positive choices need to be promoted before damaging behaviors are initiated or become ingrained.

• Journal of the Korean Society of School Health
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• v.16 no.2
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• pp.45-55
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• 2003

This study was focused on comparing the knowledge, attitudes and experiences in sex and the needs for sex education of nursing students and non-nursing students. The subjects of this study were 403 female students who attended 4 universities in Busan. The data was collected from November 2002 to December, and analyzed by frequency, percentage, mean, standard variance, t-test and Chi-square. The results were as follows: 1. The mean score of sex knowledge of the nursing students was 13.29 and the non-nursing students's was 11.11. There was a difference(p=0.000) between nursing and non-nursing students in sex knowledge. 2. The mean score of sex attitude of nursing and non-nursing students was 25.64, 26.65 respectively. There was no statistical difference. 3. 61.8% of the nursing students and 62.3% of the non-nursing students had experienced a relation with the opposite sex. Kissing experience was 59.9%, 61.8% and masturbation was 9.5%, 9.2% respectively. Sexual intercourse was 5.3%, 11.9% and contraception was 1.9%, 8.2% respectively. Among these experiences, sexual intercourse and contraception experience rate were different(p=0.017, p=0.002 respectively) between nursing and non-nursing students. 4. Of 19 sexual education contents, only 'the dignity of life' showed a difference. That is, more nursing students(92.9%) wanted to know about 'the dignity of life' than non-nursing students(85.7%). Among the respcndent's needs on the sexual education contents, 'Contraception' was rated first and followed by 'Sex psychology of men and women', 'Pregnancy', 'Prevention of sexual crime' and 'Sexually transmitted diseases'. Most of the respcndents(95.8%) wanted sex education introduced in the :first year of university, and presented as a special class. Specifically, 50.0% of the students wanted the education to be more realistic and systemic. With the above results, when university faculties are sexual educating to university students, they have to aware of the difference of target students. And they need to stress more realistic and specific aspect of sexual education learning rather than theoretical teaching.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5287-5291
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• 2013

The human papilloma virus (HPV) causes skin and mucous membrane infections. It crosses from one person to another by skin-to-skin contact, such as sexual contact. There are more than 100 types of HPV that can influence different parts of the body. Some types of HPV can cause cancer (such as cervical or anal cancer) and others can cause warts (such as genital or plantar warts). HPV infection is one of the most common sexually transmitted infections (STIs) in Iran and around the world. Considerable molecular evidence suggests a role for human papilloma virus (HPV) in the pathogenesis of carcinoma. Epidemiological studies on human papilloma viruses (HPVs) infections in general population are critical for the performing of health policy guidelines for developing the strategies to hinder the primary and secondary different cancer. In different parts of Iran, there is a lack of population-based studies to determine the prevalence of HPV in the general population. The aim of this population-based study was therefore to report the prevalence ratse of HPV types among Iranian patients. To study the risk of human papilloma virus (HPV) infection, we managed a retrospective study in Kerman province, southeast of Iran. For this purpose, 410 patients tested for the presence of HPV DNA using PCR and INNo-Lipa assays. HPV DNA was detected in 108 out of 410 patients (26.34%), while it was not detected in any of the control group samples. Patients included 23 (21.1%) males and 86 (78.8%) females. HPV type 6 was the most common (49%) followed by HPV type 16 (10.1%), and also HPV type11 (9.2%). The prevalence of HPV in Iran is comparable to those reported in other regions of the world. In a similar manner, it seems that HPV types 6, 16 and11 are the most common types in Kerman. Additional studies on larger group of patients, particularly in those with pre-invasive forms of disease, are needed to explain the roles of different HPV types in this location of Iran.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.5
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• pp.3333-3343
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• 2015

The purpose of this study is to investigate factors related to substance use focusing on the sexual experiences and risky sexual behaviors among Korean adolescents. This study conducted with a secondary data analysis using the Seventh Korea Youth Risk Behavior Web-based Survey 2011 in South Korea. The study participants selected 75,643 Korean adolescents who were recruited anonymously through national web-based survey. Data were analyzed using descriptive statistics, rao-Scott ${\chi}^2$, and logistic regressions considering complex samples. Results indicated that substance use was significantly associated with sexual experiences such as sexual intercourse with the opposite sex (adjusted OR=5.691; 95% CI=4.223-7.670), sexual intercourse with the same sex (adjusted OR=21.180; 95% CI=14.704-30.507) and risky sexual behaviors such as sexual assaults (adjusted OR=9.936; 95% CI=7.217-13.680), date rape (adjusted OR=16.979; 95% CI=11.648-24.751), sexual intercourse after drinking (adjusted OR=6.564; 95% CI=3.986-10.810), unexpected pregnancies (adjusted OR=18.628; 95% CI=8.476-40.936), and sexually transmitted diseases (adjusted OR=21.872; 95% CI=13.920-34.367) in Korean adolescents. Findings of this study show that adolescents who use substances are more likely to engage in risky sexual behaviors. Therefore, intervention program should be designed to consider both substance use and sexual problems and to include the effective approaches at the family and school level.