The objective of this study was to obtain acute (single) oral dose toxicity information on Lactobacillus-fermented Araliae Continentalis Radix aqueous extracts (fACR) in female and male ICR mice, as compared with Araliae Continentalis Radix aqueous extracts (ACR). After administering a single oral dose of fACR, no treatment-related mortalities were observed within 14 days after the end of treatment up to 2,000 mg/kg, the maximum dosage for rodents of both sexes; moreover, no fACR treatment-related changes in the body and organ weights, clinical signs, necropsy, and histopathological findings were detected in this experiment. In addition, no ACR 2,000 mg/kg treatment-related mortalities, clinical signs, body and organ weights, or gross and histopathological findings were observed, as compared with equal genders of vehicle control. The results obtained in this study suggest that fACR is non-toxic in mice and is, therefore, likely to be safe for clinical use. The LD50 and approximate LD in female mice and male mice, respectively, were considered after a single oral dose of fACR over 2,000 mg/kg, the maximum dosage for rodents. In addition, no specific targets or clinical signs were detected in the present study. ACR 2,000 mg/kg-treated mice also did not show any treatment-related mortalities, clinical signs, changes to body and organ weights, or gross and histopathological findings, as compared with equal genders of vehicle control.
A total of 582 gilts and barrows were analyzed to investigate the regressive relationships to slaughter weight (SW) of variables related to production efficiency and pork quality. Average initial weights and SW were 88.6 and 122.5 kg, respectively, for gilts and 88.7 and 121.4 kg, respectively, for barrows. Average daily gain and gain:feed ratio were not affected by SW. Backfat thickness, which was significantly greater (p<0.01) in barrows (23.3 mm) than in gilts (20.7 mm), increased with increasing SW (0.21 mm/kg; p<0.001). When the 4-notch carcass yield and quality grades were quantified according to an arbitrary 1 point-per-1 notch scale, the former, but not the latter, regressed on SW (-0.64/10 kg; p<0.01). The percent yield of the belly per total lean (overall mean=20.7%) increased with increasing SW (0.37%/10 kg; p<0.001), whereas in other cuts, the SW effect was negligible. The redness of the loin also increased with increasing SW (p<0.05), but other physicochemical characteristics were minimally influenced by SW. In sensory evaluation, effects of SW for fresh and cooked loin, ham, and belly were mostly considered insignificant in terms of quality, albeit statistically significant in several cases. However, positive regressions on SW (p<0.01) of the marbling and acceptability scores of fresh loin as well as the fat:lean ratio of fresh belly were noteworthy. Collectively, SW of approximately 125 kg was maximal for both sexes under the current carcass yield grading, in which 94 kg is the upper weight limit for grade A carcass. However, if the carcass weight limit of the grading was to be removed or broadened, the SW for gilts (but not that for barrows because of their excessive fat content at above 125-kg SW) could be increased to 135 kg or greater without compromising carcass quality.
Purpose: To analyze the ridge profile of the anterior maxilla using cone-beam computed tomography and to assess the clinical significance of the ridge profile by performing virtual implant placement. Methods: Thirty-two cone-beam computed tomography scans of anterior maxillae were included. For each tooth, a vertical line was made along the longitudinal axis, and 3 horizontal lines at 1-, 3-, and 5-mm levels below the labial bone crest were drawn perpendicularly to the vertical reference. At these levels, the thickness of the alveolar ridge (RT), and the labial (LT) and palatal bone plate (PT) were measured. Then, virtual implant placement using standard and tapered implants was performed. A generalized linear mixed model was used for statistical analysis. Results: The teeth were located labially based on the proportion of LT and PT with respect to RT. At the 1-mm level, the value of LT was between $1.0{\pm}0.4mm$ for central incisors and $1.3{\pm}0.6mm$ for canines. A large number of teeth had area(s) with less than 1-mm-thick labial bone between the 1- and 5-mm levels below the crest. The mean PT was generally thicker than the LT in all tooth types. The greatest mean value of labial concavity was observed for canines, compared to other tooth types. Men had a greater RT than did women, but had a comparable LT. Less apical fenestration was observed when tapered implants were used. Conclusions: Most teeth in the anterior maxilla had a thin labial bone plate, with no significant difference between sexes. Tapered implants may be advantageous for the anterior maxilla.
Lee, Hae Won;Jeong, Jae Mook;Yu, Hyo Jae;Hwang, Kang Seok;Oh, Si Eun;Song, Se Hyun
Korean Journal of Ichthyology
/
v.33
no.1
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pp.37-42
/
2021
This study sought to reveal spawning period and sex inversion of black seabream, Acanthopagrus schlegelii collected off the coast of Tongyeong, Korea. The monthly gonodosomatic index (GSI) showed the same pattern of between both sexes, and it was estimated that black seabream spawned once a year (between April and May). Histological examination revealed the transition from male to female sex, size of fork length bisexual gonad with ovarian (primary hermaphrodite; progress from male to female, MF) was seen at 20.5 to 39.6 cm and bisexual gonad with testicular (post hermaphrodite; female development and Male degeneration, FM) was seen at 26.4 to 50.2 cm. The egg diameters was in the range of 0.02 to 0.60 mm, with the smallest average egg diameter of 0.09 mm in February, the highest average egg diameters of 0.43 mm in August, and the range of fecundity was number of eggs 277,148 (33.9 cm) to 2,772,421 (34.1 cm).
This study sought to find out what the most ideal and appropriate native English speakers-Korean English teacher cooperative class model and the defining factors for organizing effective cooperative classes in the English education environment of our country. To achieve this goal, a total of 165 sixth graders of five elementary schools in Seoul were subject to the study. For about a month from April 1 to April 30, 2019, the survey and statistical analysis were conducted, including multiple return analysis, correlation analysis, cross analysis, and t/F verification. In summary, the results of the study are as follows. First, it was found that among the recognition of cooperative classes between native English speakers and Korean English teachers, it affected the defining factors in the order of class-related skills, task orientation, teaching-learning strategies, and motivation. Second, based on learner characteristics, the difference in perception of cooperative classes between native English speakers and Korean English teachers was verified, and the perception of native-Korean English teachers' cooperative classes was different depending on gender and the type of English cooperative classes currently participating, but the recognition of native-Korean English-Korean English cooperative classes, which were statistically significant, was not confirmed. Third, according to learner characteristics, the difference in the definition factors of the learner was verified and the difference between the sexes occurred, but the learner-defined factors according to the current type of English cooperative class did not occur. Also, there was no difference in the definition factors of scholars according to the type of English cooperative classes desired.
Objective: The objective of the present study was to investigate pork quality from Hereford${\times}$Berkshire female and intact male pigs reared outdoors in an alternative production system. Methods: Berkshire purebred sows were artificially inseminated, once in the fall and again in the spring of the following year, with semen from Hereford boars and managed free of antibiotics in an outdoor hoop structure until the last month of pregnancy, after which they were moved to a pasture-based unit of 0.8 hectares with individual lots with a farrowing hut, shade, and water ad libitum. Piglets were weaned at 4 weeks of age and housed in a deep-bedded hoop structure, grouped by sex. Animals were harvested at market weight of 125 kg, approximately 200 days of age. Hot carcass weight was collected at the time of the harvest. After 24 hours of refrigeration, carcass characteristics were measured. Longissimus dorsi samples collected from the right side loin. Loins were cut into 2.54-cm thick chops and were used to measure marbling score, color score, drip loss, and ultimate pH. Sensory panel tests were conducted as well at North Carolina State University. For pork characteristics and sensory panel data, trial and sex were included in the statistical model as fixed effects. Hot carcass weight was included in the model as a covariate for backfat thickness. Results: Neither the subjective nor the objective color scores displayed any differences between the boars and the gilts. No difference was found for pH and marbling score between trials or sexes. Gilts had a thicker backfat measurement at the last lumbar and a narrower longissimus muscle area measurement when compared to the boars. The only difference in the sensory characteristics was found between the trials for texture and moisture scores. Conclusion: Consumers were not able to detect boar taint under the condition of this study, which is that the intact males were reared outdoors. Additional trials would be necessary; however, based on the results of the present study, outdoor rearing can be suggested as a solution to the issue of boar taint.
Park, Sungho;Jeong, Harim;Kwon, Cheolwoo;Kim, Jonghwa;Yun, Ilsoo
The Journal of The Korea Institute of Intelligent Transport Systems
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v.18
no.4
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pp.31-43
/
2019
Take-overs occur in autonomous vehicles at levels 3 and 4 based on SAE. For safe take-over, it is necessary to set the time required for diverse drivers to complete take-over in various road conditions. In this study, take-over time and stabilization characteristics were measured to secure safety of take-over in autonomous vehicle. To this end, a virtual driving simulator was used to set up situations similar to those on real expressways. Fifty drivers with various sexes and ages participated in the experiment where changes in traffic volume and geometry were applied to measure change in takeover time and stabilization characteristics according to various road conditions. Experimental results show that the average take-over time was 2.3 seconds and the standard deviation was 0.1 second. As a result of analysis of stabilization characteristics, there was no difference in take-over stabilization time due to the difference of traffic volume, and there was a significant difference by curvature changes.
The purpose of this study was to evaluate the clinical significance of ultrasonographic classification of fatty liver in three grades. From June 2018 to April 2019, 1047 patients (818 males and 229 females) diagnosed as fatty liver among 3607 patients who underwent abdominal ultrasonography at Busan screening center. Ultrasonography was classified into three grades: Grade I (mild fatty liver), Grade II (moderate fatty liver), and Grade III (severe fatty liver) according to the degree of parenchyma texture, acoustic attenuation, Obesity index, hematological test, and metabolic syndrome. The average age of men in each sex increased with the increase of the fatty liver. Body mass index (BMI) and waist circumference were significantly increased in both men and women (p=.000). hematological analysis showed that AST, ALT, ${\gamma}-GTP$, TG, fasting blood sugar, and glycated hemoglobin were significantly different from each other (p<.05). In women, ALT, ${\gamma}-GTP$ and TG showed a significant difference with increasing fatty liver (p<.05). The prevalence of metabolic syndrome was significantly increased in both sexes as the grade of fatty liver increased (p=.000). Based on the results of this study, it is suggested that the use of ultrasound - guided fatty liver according to severity may be useful for the treatment and follow - up of fatty liver if the liver grade is divided in consideration of hematological variables and metabolic syndrome.
According to the OECD (2015) and UN (2017), Korea was classified as an immigration country. The designation as an immigration country means that net migration will remain positive and international migration is likely to affect population growth. KOSTAT (2011) used a model with more than 15 parameters to divide sexes, immigration and emigration based on the Wilson (2010) model, which takes into account population migration factors. Five years later, we assume the average of domestic net migration rate for the last five years and foreign government policy likely quota. However, both of these results were conservative estimates of international migration and provide different results than those used by the OECD and UN to classify an immigration country. In this paper, we proposed a stochastic projection on international migration using nonparametric model (FDM by Hyndman and Ullah (2007) and Coherent FDM by Hyndman et al. (2013)) that uses a functional data model for the international migration data of Korea from 2000-2017, noting the international migration such as immigration, emigration and net migration is non-linear and not linear. According to the result, immigration rate will be 1.098(male), 1.026(female) in 2018 and 1.228(male), 1.152(female) in 2025 per 1000 population, and the emigration rate will be 0.907(male), 0.879(female) in 2018 and 0.987(male), 0.959(female) in 2025 per 1000 population. Thus the net migration is expected to increase to 0.191(male), 0.148(female) in 2018 and 0.241(male), 0.192(female) in 2025 per 1000 population.
Kim, Seong Jin;Song, Je Seon;Kim, Ik-Hwan;Kim, Seong-Oh;Choi, Hyung-Jun
Journal of the korean academy of Pediatric Dentistry
/
v.48
no.3
/
pp.255-268
/
2021
The aim of this study was to investigate the relationships between the stages of calcification of various teeth and skeletal maturity stages among Korean subjects. The samples were derived from hand-wrist, panoramic radiographs, and lateral cephalograms of 743 subjects (359 males and 384 females) with ages ranging from 6 to 14 years. Calcification of seven permanent mandibular teeth on the left side were rated according to the system of Demirjian. To evaluate the stage of skeletal maturation, hand-wrist radiographs were analyzed by skeletal maturity indicators (SMI) system of Fishman and lateral cephalograms by cervical vertebral maturation (CVM) method of Baccetti. Statistically significant relationships were found between dental calcification and skeletal maturity stages according to Spearman rank-order correlation coefficients (r = 0.40-0.84, p < 0.001). The second molar showed the highest correlation and central incisor showed the lowest correlation for female and male subjects. For both sexes, canine stage G and second molar stage F were related to SMI 6 and CS 3. Because of the high correlation coefficients, this study suggests that tooth calcification stages from panoramic radiographs might be clinically useful as a maturity indicator of the pubertal growth period in Korean patients.
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