• 대한정형외과학회지
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• 제56권3호
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• pp.215-223
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• 2021

목적: 소아 요골 원위부 골절은 가장 흔한 골절이면서 불안정 골절의 경우 정복 후에도 재전위 위험성이 높아 주의가 요망된다. 이러한 재전위에 영향을 미치는 요인들에 대하여 평가해 보고자 한다. 대상 및 방법: 2011년 2월부터 2018년 6월까지 완전 전위된 소아 요골 원위부 불안정 골절로 본원 외래에서 보존적 치료한 6세에서 14세까지의 환자들을 대상으로 후향적 연구를 하였다. 전체 대상 환자 44예 중 재전위된 환자들에서 연령, 성별, 석고 지표, 간격 지표, 3점 고정 지표, 골절면 경사도, 관절면에서 골절선까지 거리를 환산한 골절 높이 비, 요골-제2 중수골 각도 등을 측정하여 마지막 골유합 상태에서 남은 각형성의 정도로 결과를 평가하여 비교를 하였다. 결과: 평균 9.2도(0-32.8도) 각형성이 남았으며 범주 내의 결과를 기준으로 하여 10도 미만이 29예, 10도 이상이 15예로 확인되었다. 정복 후 재전위가 발생한 군과 대조군 사이에 평가된 요소들 중 석고 지표들은 두 군 간에 차이가 없었다. 연령, 성별에서도 군 간에 차이가 없었고, 골절면 경사도, 요골-제2 중수골 각도도 차이가 없었다. 관절면에서 골절선까지의 거리를 환산한 골절 높이 비가 가장 의미 있는 안정요소로 평가되었고(p=0.001) 척골 골절이 동반된 경우도 불안정한 요소로 평가되었다(p=0.019). 결론: 소아 요골 간단부 완전 전위 골절, 특히 요골 골간단-골간 이행부의 골절의 경우 불안정한 골절로 평가되므로 좀 더 주의가 필요하며 충분한 재형성을 기대하기 어려운 연령에서는 만족스러운 결과를 위하여 수술적 치료가 선호될 수 있다.

• Animal Bioscience
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• 제35권6호
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• pp.916-926
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• 2022

Objective: This study was conducted to evaluate the effects of medium chain triglycerides (MCT) with organic acids (OA) on growth performance, fecal score, blood profiles, intestinal morphology, and nutrient digestibility in weaning pigs. Methods: A total of 120 weaning pigs ([Yorkshire×Landrace]×Duroc) with an average body weight (BW) of 8.00±0.87 kg were assigned in five treatments considering sex and initial BW in 3 replications with 8 pigs per pen in a randomized complete block design. The experimental diets included a corn-soybean meal based basal diet with or without 0.1% or 0.2% MCT and 0.1% OA. The pigs were fed the diets for 5 weeks (phase 1, 0 to 2 weeks; phase 2, 3 to 5 weeks). A total of 15 barrows with an average BW of 12.48±0.37 kg were used to evaluate the nutrient digestibility by total collection method. The BW and feed intake were measured at the end of each phase. Blood samples and small intestine samples were collected at the end of each phase, too. Results: Supplementing 0.1% MCT with 0.1% OA showed greater BW for week 5 and average daily gain (ADG) for overall period than control diet. Supplementing 0.1% MCT increased (p<0.05) ADG and improved (p<0.05) gain:feed ratio for phase 1. Dietary MCT and OA did not affect the fecal score and blood concentration of cortisol, immunoglobulin G, tumor necrosis factor-α, interleukin-1β (IL-1β), IL-6, and IL-10 in weaning pigs. Pigs fed the diets with 0.1% MCT had greater (p<0.05) villus height of duodenum and ileum for phase 1. Also, pigs fed the diet with 0.1% OA showed greater (p<0.05) villus height and villus height to crypt depth ratio of duodenum for phase 2. There was no significant difference in nutrient digestibility and nitrogen retention of pigs. Conclusion: Addition of 0.1% MCT with 0.1% OA in weaning pig's diet improved growth performance partly by enhancing intestinal morphology in weaning pigs.

• Journal of Dental Anesthesia and Pain Medicine
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• 제23권1호
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• pp.29-37
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• 2023

Background: A high incidence (40-73%) of postoperative nausea and vomiting (PONV) has been reported following orthognathic surgery, and various risk factors have been associated with it. Identifying PONV risk factors based on initial onset time will help establish preventive measures. This study aimed to identify factors that are significantly related to PONV based on the initial onset time after orthognathic surgery. Methods: This study included 590 patients who underwent orthognathic surgery. Multivariate logistic regression analysis was performed to identify the risk factors that are significantly related to PONV. The objective variables were classified into three categories: no PONV, early PONV (initial onset time: 0-2 h after anesthesia), and late PONV (initial onset time: 2-24 h after anesthesia). The explanatory variables included relevant risk factors for PONV, as considered in previous studies. Results: Total intravenous anesthesia with propofol was a significant depressant factor for early PONV (adjusted odds ratio [aOR] = 0.340, 95% confidence interval [CI] = 0.209-0.555) and late PONV (aOR = 0.535, 95% CI = 0.352-0.814). The administration of a combination of intraoperative antiemetics (vs. no administration) significantly reduced the risk of early PONV (aOR = 0.464, 95% CI = 0.230-0.961). Female sex and young age were significant risk factors for late PONV (aOR = 1.492, 95% CI = 1.170-1.925 and unit aOR = 1.033, 95% CI = 1.010-1.057, respectively). Conclusion: We identified factors that are significantly related to PONV based on the initial onset time after orthognathic surgery. Total intravenous anesthesia with propofol significantly reduced the risk of PONV not only in the early period (0-2 h after anesthesia) but also in the late period (2-24 h after anesthesia).

• 대한통합의학회지
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• 제11권3호
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• pp.99-114
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• 2023

Purpose : The purpose of this study was to determine factors that affect the quality of life (QoL) of people with diabetes. We hope to provide a basis for intervention strategies for health promotion and related research among patients with diabetes in the field of physical therapy. Methods : We selected individuals diagnosed with diabetes who were aged 19 years or higher by using data from the 2019 Korean Health Panel survey and analyzed the results of 1,527 people. The influencing factors were sex, age, household income, marital status, age, education level, subjective health status, body mass index (BMI), smoking, drinking, regular exercise, experience of depression and anxiety, suicidal thoughts, stress, and frequency of walking (days/week). Frequency analysis, descriptive statistics, independent sample t-test, one-way analysis of variance, and multiple regression analysis were performed. Results : The EQ-5D score for QoL was .87 ± .12, with pain and discomfort being the most detrimental to the QoL of people with diabetes. In terms of patients characteristics, the QoL was lower among participants who were female, older, and separated/widowed/divorced; had an education level below middle school; had a poor subjective health status; were non-smokers and drinkers; and did not walk and exercise regularly, experienced a lot of stress, and experienced depression and anxiety; and had suicidal thoughts (p<.001). Being separated/bereaved/divorced; experiencing a lot of stress, depression, and anxiety; and having suicidal thoughts were negatively associated with QoL in people with diabetes (p<.01). On the other hand, age of 65 years or younger; graduation from high school, fair or better subjective health, regular exercise and alcohol consumption, and walking (days/week) were positively associated with QoL (p<.05). Conclusion : Regarding the QoL of patients with diabetes, intervention strategies should be formulated by considering general characteristics and disease-related characteristics. Among the various factors affecting QoL, the number of walking and regular exercise were found to be the factors that improved the QoL of patients with diabetes. These results can be used as a basis for the education and management of patients with diabetes in the field of physical therapy.

• Animal Bioscience
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• 제36권8호
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• pp.1228-1240
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• 2023

Objective: This experiment was conducted to evaluate the effects of different levels of dietary crude protein (CP) on growth performance, blood profiles, diarrhea incidence, nutrient digestibility, and odor emission in weaning pigs. Methods: A total of 240 weaning ([Yorkshire×Landrace]×Duroc) pigs (8.25±0.050 kg body weight [BW]) were assigned to six treatments based on sex and initial BW, with five replicates of eight pigs per pen in a randomized complete block design. Experimental diets with different crude protein levels for early and late weaning phases were as follows: i) CP16, corn-soybean-based diet containing 16%/15% CP; ii) CP17, corn-soybean-based diet containing 17%/16% CP; iii) CP18, corn-soybean-based diet containing 18%/17% CP; iv) CP19, corn-soybean-based diet containing 19%/18% CP; v) CP20, corn-soybean-based diet containing 20%/19% CP; and vi) CP21, corn-soybean-based diet containing 21%/20% CP. Results: In the early weaning period, average daily feed intake increased when the dietary CP level decreased (linear, p<0.05). During the entire experimental period, average daily gain and the gain to feed ratio decreased when the dietary CP level increased (linear, p<0.01). Additionally, a decrease in dietary CP level resulted in a linear increase in final BW (linear, p<0.05). In the early and late weaning periods, blood urea nitrogen (BUN) decreased when the dietary CP level decreased (linear, p<0.01). There were no significant differences in creatinine, glucose, total protein, triglyceride or insulin-like factor-1 levels over the experimental period. The concentrations of immunoglobulin A (IgA) and IgG were not significantly affected by dietary CP levels during the experimental period. In the early weaning period, fecal and urine N decreased when the dietary CP level decreased (linear, p<0.01). No differences in nutrient digestibility among the treatments during the early weaning period were found. Throughout the whole experimental period, when the dietary CP level decreased in the weaning pig diet, the diarrhea incidence decreased linearly (linear, p<0.01). Throughout the whole experimental period, when the dietary CP level decreased in the weaning pig diet, ammonia, amines and hydrogen sulfide decreased linearly (linear, p<0.01). Conclusion: Reducing dietary CP could decrease diarrhea incidence, the concentration of BUN in serum and odor emission in manure. Furthermore, it could improve N excretion in feces and urine and growth performance in weaning pigs.

• Journal of Veterinary Science
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• 제23권2호
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• pp.20.1-20.8
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• 2022

Background: Emergent and re-emergent canine tick-borne infections are attracting increasing attention worldwide. The rise in pet ownership and the close relationship between dogs and their owners are the most concerning factors because dogs may act as competent reservoirs for human tick-transmitted infectious agents. Objectives: This study contributes to the epidemiological surveillance of canine tick-transmitted infections with zoonotic risk in the Republic of Korea (ROK) by investigating the seroprevalence of the pathogens, Anaplasma spp., Borrelia burgdorferi, and Ehrlichia canis. Methods: Four hundred and thirty whole blood samples from domestic dogs were collected in seven metropolitan cities and nine provinces in the ROK and tested using SensPERT Ab test kits (VetAll Laboratories^®) to detect seroreactive animals. Results: The seroprevalence rates identified were 9.8% (42/430) for Anaplasma spp., 2.8% (12/430) for B. burgdorferi, and 1.4% (6/430) for E. canis. The risk factors evaluated in this study that could be associated with the development of a humoral immune response, such as sex, age, and history of tick exposure, were similar. There was only one exception for dogs seroreactive to Anaplasma spp., where the risk factor "tick exposure" was statistically significant (p = 0.047). Conclusions: This serological survey exhibited the widespread presence of Anaplasma spp., B. burgdorferi, and E. canis throughout the ROK. Hence, dogs may play a key role as the sentinel animals of multiple zoonotic infectious agents in the country.

• 한국노년학
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• 제27권2호
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• pp.371-392
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• 2007

이 연구의 목적은 노인인구에 대한 전국규모의 자료를 활용하여 노년기 결혼지위 점유와 건강의 관련성을 실증적으로 밝히는데 있다. 이 연구에서는 첫째, 사별노인과 유배우 노인의 신체 및 정신 건강, 사회관계망의 내용을 비교하였고, 둘째, 유배우노인과 사별노인 간의 건강격차가 사회관계망 특성에 의해 설명되는지를 검증하였다. 마지막으로, 사회관계망이 건강에 미치는 효과가 유배우/사별노인에서 어떠한 차이가 있는가를 살펴보았다. 한국보건사회연구원의 <2004년도 노인실태조사자료>를 분석한 결과, 결혼지위 점유에 따른 신체 및 정신건강 수준은 노인의 연령과 건강차원에 따라 그 양상이 상이하였다. 지각된 건강, 주요 만성질환 수에서는 노인의 결혼지위 점유에 따른 건강 격차가 크지 않았고, 관찰되는 차이는 성, 연령, 계층 등의 사회·인구학적 특성이 고려되자 감소하였다. 그런데 행복감 차원에서는 성과 연령을 비롯한 사회·인구학적 특성이 고려된 이후에도 유배우자는 사별자보다 행복감을 높게 지각하였다. 친한 친구/이웃 접촉, 친한 자녀접촉, 사회활동으로 요약되는 사회관계망의 특성이 신체 및 정신건강에 미치는 효과에서는 사별노인과 유배우 노인에서 차이가 있었다. 이는 사회관계망의 필요성이나 기능이 노인의 결혼지위에 따라 다름을 의미한다.

• 한국노년학
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• 제39권4호
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• pp.741-762
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• 2019

본 연구는 지역사회에 거주하는 노인 1인 가구의 노인영양지수(Nutrition Quotient for Elderly, NQ-E)를 파악하고, 영양 수준에 영향을 미치는 생활실태 특성을 규명함으로써 노인 1인 가구가 지역사회 내에서 건강한 노후를 영위할 수 있는 개입 방안을 고찰하고자 실시되었다. 조사 대상은 전국에 만 65세 이상 1인 단독가구 노인 1,970명을 편의표집방법으로 조사하였으며, 사회복지기관 25곳과의 조사 협조체계를 구축하고 독거노인생활관리사 385명이 설문조사 요원으로 참여하였다. 조사 결과 노인영양지수(NQ-E)는 평균 51.14점으로 '하' 등급'을 나타냈으며, 다중회귀분석의 설명력은 20.1%로 나타났다. 유의미한 변인으로는 여성인 경우, 연령이 낮을수록, 동부에 거주하는 경우, 주관적 건강상태가 좋은 경우, 복약 수가 적을수록, 비흡연자인 경우, 과음주가 아닌 경우, 경제상태 만족도가 좋은 경우, 식비 비중이 30% 이상인 경우, 무학이 아닌 경우, 가족 및 이웃과의 교류가 많을수록 노인영양지수(NQ-E)를 높이는 예측변인이 됨을 알 수 있었다. 본 연구결과를 근거로 향후 노인 1인 가구의 영양관리 및 향상을 위한 포괄적인 대책이 모색되어야 할 것이다.

• 대한영상의학회지
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• 제83권2호
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• pp.317-330
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• 2022

목적 본 연구는 신장종양 환자에서 시행한 고주파절제술 이후 신장 기능에 영향을 미치는 다양한 요소들에 대한 평가를 통해서 이들의 상관관계와 임상적 가치를 평가하기 위한 것이다. 대상과 방법 2010년 1월부터 2018년 12월까지 본원에서 ultrasonography, CT 유도하에 고주파절제술을 시행 받은 91명을 대상으로 선정하였다. 신기능을 평가하는 방법으로 시술 직전과 시술 이후 혈청 크레아티닌, 사구체 여과율을 측정하였다. 시술 전과 비교하여 혈청 크레아티닌 수치가 0.3 mg/dL 이상 증가하는 것을 유의미한 것으로 정하고, 이에 근거하여 두 그룹으로 분류하였다. 신장 기능 손상에 영향을 미치는 요소를 평가하기 위해서 다변수 로지스틱 회귀분석을 이용해서 그룹 간에 비교를 시행하였다. 결과 단일 신장, 3단계 이상의 만성 콩팥병, 요관 손상은 신장 기능 손상에서 통계적으로 유의한 의미가 있었다. 성별, 연령, 다른 암, 종양 크기, 위치, 성장 형태, 집합계와의 근접성 등은 통계적으로 유의하지 않았다. 신장 기능 수치의 시간에 따른 변화는 단일 신장, 3단계 이상의 만성 콩팥병, 요관 손상 유무에 따라서 통계적으로 유의하게 달랐다. 결론 고주파절제술 시행 전의 의학적 상태 중 단일 신장, 3단계 이상의 만성 콩팥병, 시술 이후 발생한 합병증 중 요관 손상은 시술 이후 발생하는 신장 기능 손상의 위험요소로 생각할 수 있다.

• Annals of Occupational and Environmental Medicine
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• 제35권
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• pp.22.1-22.9
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• 2023

Background: Shift work increases the risk of chronic diseases, including metabolic diseases. However, studies on the relationship between shift work and renal function are limited. The aim of this study was to investigate the association between shift work and a decreased glomerular filtration rate (GFR). Methods: Data were evaluated for 1,324,930 workers who visited the Korean Medical Institute from January 1, 2016 to December 31, 2020 and underwent a health checkup. Daytime workers were randomly extracted at a ratio of 1:4 after matching for age and sex. In total, 18,190 workers aged over 40 years were included in the analyses; these included 3,638 shift workers and 14,552 daytime workers. Participants were categorized into the shift work group when they underwent a specific health checkup for night shift work or indicated that they were shift workers in the questionnaire. The odds ratio was calculated using a conditional logistic regression to investigate the relevance of shift work for changes in GFR. Results: 35 workers in the shift group and 54 in the daytime group exhibited an estimated GFR (eGFR) value of < 60 mL/min/1.73m² (p < 0.01). The difference in eGFR values between two checkups differed significantly depending on the type of work (p < 0.01); the difference in the shift work group (-9.64 mL/min/1.73 m²) was larger than that in the daytime work group (-7.45 mL/min/1.73 m²). The odds ratio for eGFR reduction to < 60 mL/min/1.73 m² in the shift group versus the daytime group was 4.07 (95% confidence interval: 2.54-6.52), which was statistically significant. Conclusions: The results of this study suggest that eGFR decreases by a significantly larger value in shift workers than in daytime workers; thus, shift work could be a contributing factor for chronic kidney disease (CKD). Further prospective studies are necessary to validate this finding and identify measures to prevent CKD in shift workers.