• Title/Summary/Keyword: Sex/gender differences

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Effect of gender on the pharmacokinetics and metabolite formation of sulfamethazine in the rabbit (토끼의 성차가 sulfamethazine의 약동학 및 대사산물 생성에 미치는 영향)

  • Yun, Hyo-in;Park, Il-hyun
    • Korean Journal of Veterinary Research
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    • v.32 no.1
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    • pp.35-39
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    • 1992
  • SMZ is one of the most widely used antibacterial agents in veterinary medicine. It is also used as a growth promotant in many species of domestic animals There are marked species differences in its metabolism and pharmacokinetics. However, its pharmacokinetic and metabolism in rabbits. which are ragarded not only as good laboratorty animals hut also as good economical animals in its own, are lacking. Sex-differences in drug metabolism are well recognized in wide range of animal species including rats. Males are known to he more active than females. It is also know that there are Significant differences in the direction of metabolic pathways. But recently, female goats are reported to be more active in the metabolie capacity of SMZ than the other sex by Dutch researchers at Utrecht. Therefore, it is not easy to make general conclusicn of having higher SMZ metal-die capacity in the male compared to the opposite sex in every animal species. In this regard, the study on metabolic pattern of SMZ in rabbits, which are regarded as hervivorous, is of interest because the dietary habbits of rabbit are comparable to thai of goal, NEW Zealand White rabbits of each sex were given SMZ(35mg/kg) as a bolus injection into the marginalean, vein in order to study its pharmacokinetic profiles(using plasma) anc metabolic pattem(24h urine) as specified in the methods anc materials. 1. In the rabbit, the major metabolic pathway of SMZ was the acetylation(the formation of $N_4AcSMZ$). There were hydroxylation pathways(50HSMZ, $6CH_2OHSMZ$) as well, in the metabolism of SMZ in the rabbit, but minor pathways. 2. No sex differences in the metabolic direction of SMZ and its metabolites formation were found from the urinary excreted metabolites of SMZ out of 24h collected urine. 3. The concentration-time curves of SMZ(35mg/kg, iv) in the plasma compartment were fitted to a one-compartment open model when using a computer program(NONLIN). There was also no difference in the pharmacokinetic pattem of SMZ between two sexes. 4. The emergence of $N_4AcSMZ$ metabolized from SMZ was very fast in the plasma of the rabbit The elimination of $N_4AcSMZ$ was prolonged as compared to that of the parent drug Vie found no sex difference in the elimination pattern of $N_4AcSMZ$ in the rabbit.

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Effects of Oral-Administered 17α-Methyltestosterone and Estradiol-17β for Sex Reversal of Hybrid Sturgeon, Bester Juvenile (베스테르 철갑상어 치어 성전환을 위한 17α-methyltestosterone과 estradiol-17β 경구투여 효과)

  • Kwon, O-Nam;Adachi, Shinji
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.6
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    • pp.585-590
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    • 2009
  • The purpose of this study was to examine the effects of oral-administered sex hormone for hybrid sturgeon, bester juvenile. The bester juveniles (2 months after hatching) were received a diet containing various doses of $17\alpha$-methyltestosterone (MT) or estradiol-$17\beta$ ($E_2$) for 6 months. Somatic growth of bester sturgeon juvenile did not show significant differences between experimental and control groups (27.9-30.5 cm; 125.1-161.7 g), although survival percentages showed a decreasing tendency in MT-treated animals. By histological examination, germ cells were recorded as smooth type in MT-treated fish and uneven type of germinal epithelium in $E_2$-treated animals. Their sex ratios were 5:4:1 (male: female: undifferentiation) in control and low dose of MT-treated fish (1 mg/kg), and 9:1:0 in fish treated with high dose of MT (10 mg/kg), whereas the ratios were reversed by both low and high doses of $E_2$ treatment, recorded as 2:8:0. Gonadal areas were not significantly differed in all trials (424,600.4 - 1,039,656.3 ${\mu}m^2$). Total number of germ cells, number of germ cells per gonadal areas and number of germ cells per area were significantly higher to 144.7-148.7 cells/section, 374.0-408.5 $cells/mm^2$ and 1,599.5-1,670.9 $cells/mm^2$ in $E_2$ treatment than those of others (30.4-63.9 cells/section, 148.4-226.9 $cells/mm^2$ and 850.0-1,050.6 $cells/mm^2$), respectively. And somatic growth according to their gender was not significantly differed between male and female.

Basic Research on Sexuality Education for Adolescents (청소년의 성교육을 위한 기초연구)

  • 문인자;조옥희;김효심
    • Journal of Korean Home Economics Education Association
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    • v.9 no.1
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    • pp.145-159
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    • 1997
  • The purpose of this study is to survey middle school students’s awareness of sexuality and relationships with the opposite sex. The students need to have at their disposal basic resources on sexuality education and an established and systematic curriculum. To achieve this result, questionaires were distributed to 640 students who were chosen randomly in three middle schools in Seung-ju Goon and Goo-rye Goon in Chonnam area, 573 questionaries were used for the final analysis. The results were as follows: In the area of awareness of sexuality, male students regarded sex more positively than female students. It also showed that 19.9% or male students and 17.6% of female students were not aware of their virginity. Male students said they felt sexual impulses most when they saw naked women, and secondly, by sex magazines. This indicates students are motivated mostly by outside influences. There is a considerable gap in the degree of sexual knowledge between male and female according to their school year and father’s family education level. However, little difference is seen according to student’s family circumstance, father’s education level. However, little difference is seen according to student’s family circumstance, father’s job, and student’s religion and vise versa. School restrictions were so severs that 48.2% of boys and 47.1% of girls said that schools paid little attention to their needs. The school restricted rather than permitted relationships with opposite sex. Most of the students revealed a dissatisfaction with the school sexuality education program. Because of confucianism, Korean society has a negative attitude towards sexual activity including sexual education in the schools. 56.8% of male students and 81.4% of females students wanted female teachers to be their sexuality education teachers or advisors rather than male teachers, and 44.8% of male students and 51.2% of females students wanted to receive sexuality education in their Home Economics classes. Materials for sexuality education were considered most effective through videos and audio-visuals. As a result, this survey showed that there appeared to be a great need for a sound, effective, and sensitive sexuality education curriculum in the middle schools for teenagers. It should be conducted in such a way that the teenagers will learn about their sexual needs, their gender differences, and understand and know how to conduct themselves in today’s society sexually.

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Gender Differences in the Conception of Love, Sexual Attitudes, land Mate Conditions of Unmarried Men and Women (미혼남녀의 사랑과 성에 대한 태도 및 배우자 선택 조건)

  • 김경신
    • Journal of the Korean Home Economics Association
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    • v.35 no.3
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    • pp.15-30
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    • 1997
  • The purposes of this article were three folds; to find general trends of the conception of love, sexual attitudes and mate conditions of unmarried men and women, to investigate relationships among them and to analyze the effect of significant variables influencing mate conditions. The samples were the 164 unmarried men and 235 unmarried women living in Kwang-ju. Major findings were as follows; 1) Unmarried men revealed higher concern in commitment of love and they were more liberal in sexual attitudes than women. Women desired higher level of mate conditions than men compared with themselves. 2) Women's conception of love was more related to their sexual attitudes and homogeneous mate conditions than men. Men's sexual attitudes were related to their homogeneous mate conditions, while those of women were related to interactional mate conditions. 3) Men's external mate conditions were affected by job, and internal mate conditions were affected by passion of love and sex role attitude. Men's homogeneous mate conditions were affected by attitude of premarital sexual experience, intimacy of love and conception of sexuality, and those of women's were affected by passion of love and age. Men's interactional mate conditions were affected by sex role attitude, job and education. Therefore unmarried men and women's conception of love and sexual attitudes were associated with homogeneous and interactional mate conditions.

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The Influences of Family Demographics and Children's Emotional Reactions on the Emotional Expressiveness of Korean Parents (가족의 인구학적 변인과 아동의 정서적 반응이 부모의 정서 표현성에 미치는 영향)

  • Song, Ha-Na
    • Journal of the Korean Home Economics Association
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    • v.44 no.1 s.215
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    • pp.75-85
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    • 2006
  • Emotional expressiveness is a pathway by which parents affect the emotional competence of their children. This study examined how the emotional expressiveness of parents is influenced by the emotional reactions of their children and demographic characteristics within a family context. Data for the present study were from 200 parents in 100 two-parent families who completed self-report questionnaires for emotional expressiveness, children's emotional reactions to stressful situations, and demographics. In preliminary analyses, mothers expressed emotions more frequently than fathers did, and mothers with high expressiveness of positive emotions were more educated and had higher family income. Although fathers' emotional expressiveness was closely related to mothers' expressiveness, none of the demographic factors were related to fathers' expressiveness. When all predictors were considered in hierarchical multiple regressions, family income was the significant predictor for mothers' positive expressiveness, whereas mothers' negative expressiveness were explained by children's emotional reactions, mother education, child sex, the number of siblings, fathers' education, and mothers' time spent with children. When controlled for mothers' expressiveness, fathers' time spent with children was the only significant predictor for fathers' negative expressiveness. The results of this study suggested that parents' emotional expressiveness varied with socioeconomic status. The discussion also examines the gender differences between mothers and fathers in emotional expressiveness, and their relations to children's sex.

Erythrocyte Sedimentation Rate: Its Determinants and Relationship with Risk Factors Involved in Ischemic Stroke

  • Kaur, Kirandeep;Kaur, Amandeep;Kaur, Anupam
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.1
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    • pp.1-8
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    • 2022
  • Erythrocyte sedimentation rate (ESR) evaluation is a useful tool for monitoring disease activity in various inflammatory and non-inflammatory conditions. ESR is known to be influenced by a multitude of confounding factors. The present study aimed to assess the possible determinants of the ESR and its relationship with various risk factors involved in ischemic stroke. ESR and other hematological and biochemical parameters were investigated in 163 ischemic stroke patients (107 males and 56 females) selected based on imaging techniques including magnetic resonance imaging (MRI) or computed tomography (CT) scans. Statistical analysis was performed using the SPSS 16.0 software. Linear regression analysis showed a significant inverse relationship of hemoglobin (Hb) and hematocrit or packed cell volume (PCV) (P<0.001 for females; P<0.01 for males) with the ESR. It was observed that the red blood cell (RBC) count was not strongly correlated with the ESR (P<0.05 for both males and females). It was also observed that sex significantly affected the variables determining the ESR levels, whereas age had no effect. Gender differences were also observed with respect to Hb, RBC, PCV, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and ESR. The possible determinants of higher ESR levels in ischemic stroke may be sex, Hb, hematocrit, and RBC count, but the role of other clinical and laboratory parameters cannot be underestimated.

Evaluations of Apparel Advertising, Fashion Involvement, and Social Attitudes (의류광고에 대한 평가, 유행몰입 및 사회적 태도에 관한 연구)

  • 김효경
    • Journal of the Korean Home Economics Association
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    • v.30 no.3
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    • pp.33-43
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    • 1992
  • The objective of this study were to (1) investigate the relationship between evaluations of apparel advertising, fashion involvement, and social attitudes, (2) examine how evaluation of apparel advertising, fashion involvement, and social attitudes vary according to gender, and (3) investigate the possible differences in purchase attitudes toward the advertised apparels according to gender and advertisement slogan. Questionnaire for evaluations of apparel advertising was comprised of four sections; apparel advertising acceptance, evaluation of advertisement slogan, purchase attitude toward the advertised apparels, and perception of effective media for apparel advertising. For evaluation of advertisement slogan, 5 sets of apparel advertisements were selected. Each set had two advertisements; one advertisement contained an image-oriented slogan, while the other had a quality-oriented slogan. "The Social Attitude Scale' by Kerlinger and 'Fashion Involvement Index' by Tigert, Ring & King were used. All the items were selected on the Cronbach's alpha reliability. The subjects were 217 college male and famale students in Seoul; 60 were asked about purchase attitude toward the image-oriented slogan, 60 purchase attitude toward the quality-oriented slogan, and 97 all the items included in evaluation of the two slogans. The data were analyzed using Pearson's correlation coefficient, X2-test, t-test, two-way ANOVA, and multiple regression analysis. The results of the study were the followings. 1. Fashion involvement had positive relationship with apparel advertising acceptance. The higher the level of conservative attitude males had, the more positive attitude they had in fashion involvement and apparel advertising acceptance. Subjects high in conservative attitude, fashion involvement, and apparel advertising acceptance. Subjects high in conservative attitude, fashion involvement, and apparel advertising acceptance had more positive in purchase of the advertised apparels. 2. Females high in apparel advertising acceptance were more favorable toward image-oriented advertisements. 3. Fashion involvement and apparel advertising acceptance were significantly higher in females than in males. Liberal attitude was significantly higher in males than in females. Evaluation of advertisement slogan did not differ according to gender. 4. Males perceived 'TV' was the most effective media for apparel advertising while females perceived 'display' was the most effective. 5. No significant interactions between advertisement slogan and gender were found in purchase attitude of the advertising apparels. 6. Apparel advertising acceptance was influenced by fashion involvement, social attitude, and sex. The explanatory power of the three variables was 17%.

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Motivations of Parenthood & Perceptions of Low Fertility according to Sex and Generations (성별과 세대에 따른 부모됨의 동기 및 저출산 현상에 대한 인식)

  • Ahn, Eun-Jin;Choi, Hyo-Jin;Yoo, Gye-Sook
    • Journal of Families and Better Life
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    • v.25 no.6
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    • pp.1-13
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    • 2007
  • The purpose of this study is to examine the college students' and married adults' perceptions of the current low fertility and their motivations of parenthood. It also verifies the gender differences in the numbers of planned children between male and female college students. The sample population included 100 unmarried undergraduate students and 100 married adults. The measurements included in the questionnaire were based on recommendations from the literature review. The major findings of this study are as follows: Women reported higher levels of traditional-normal and altruistic-emotional motivations of parenthood than men did. College students reported higher levels of motivations of parenthood to strengthen biological family ties than married adults did, while adults reported higher levels of martial bond-strengthening, traditional-normal, and gene-preservative motivations of parenthood than students did. College students attributed the current low fertility to the tight labor market and high costs of childbirth and rearing while married adults attributed to gender-discriminating traditional family norms, increasing infertility, and poor conditions of pregnancy and childbirth. Female and adult respondents took the social problems caused by the current low fertility more seriously than their counterparts did.

Association Between Socioeconomic Status and Obesity in Adults: Evidence From the 2001 to 2009 Korea National Health and Nutrition Examination Survey

  • Kim, Jihye;Sharma, Shreela V.;Park, Sung Kyun
    • Journal of Preventive Medicine and Public Health
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    • v.47 no.2
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    • pp.94-103
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    • 2014
  • Objectives: The present study examined relationships between socioeconomic status (SES) and obesity and body mass index (BMI) as well as the effects of health-related behavioral and psychological factors on the relationships. Methods: A cross-sectional population-based study was conducted on Korean adults aged 20 to 79 years using data from the 2001, 2005, and 2007 to 2009 Korea National Health and Nutrition Examination Survey. Multivariate logistic and linear regression models were used to estimate odds ratios of obesity and mean differences in BMI, respectively, across SES levels after controlling for health-related behavioral and psychological factors. Results: We observed significant gender-specific relationships of SES with obesity and BMI after adjusting for all covariates. In men, income, but not education, showed a slightly positive association with BMI (p<0.05 in 2001 and 2005). In women, education, but not income, was inversely associated with both obesity and BMI (p<0.0001 in all datasets). These relationships were attenuated with adjusting for health-related behavioral factors, not for psychological factors. Conclusions: Results confirmed gender-specific disparities in the associations of SES with obesity and BMI among adult Korean population. Focusing on intervention for health-related behaviors may be effective to reduce social inequalities in obesity.

The Influence of Health Status and Working Condition on the Absence of Adult Workers: Focusing on Gender Differences (성인 근로자의 질병 결근에 미치는 영향요인: 성별차이를 중심으로)

  • Lee, Mi-Kyoung;Lim, So-Hee
    • Korean Journal of Occupational Health Nursing
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    • v.29 no.4
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    • pp.273-287
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    • 2020
  • Purpose: This descriptive correlation study was conducted to investigate factors affecting the absence of adult workers according to their gender. Methods: Secondary data analysis was carried out using data from the fifth Korean Working Conditions Survey. Data on respondents' demographic characteristics, working conditions, health status, and absence were analyzed; a descriptive analysis, χ2-test, t-test, and logistic regression analysis were carried out. Results: The factors that had the greatest impact on male workers' absence from work were service workers (2.74 times; B=.99), having more than 53 hours of work per week (1.17 times; B=.52), and when subjective health conditions were not satisfied (2.27 times; B=.82), whereas the factors that affected female workers' absence the most were a monthly income of 3 million won or more (2.74 times; B=1.34), a weekly work time of 53 hours (2.02 times; B=.71), and having a fewer number of sleep disorders (B=-.36). Conclusion: This study suggests that not only the national interest should be considered in investigating the factors affecting absence but also the enterprise. Systematic support for the health care of workers is also needed.