• 한국가금학회지
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• 제20권2호
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• pp.55-64
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• 1993

본 실험은 육용계 기초사료에 copper와 Vit. E＋Se을 첨가급여시 육계의 혈청 IgG수준과 증체량 및 질병 발생율과의 상관관계를 조사함으로써 가금의 영양과 면역반응에 관한 기초적인 정보를 얻고자 실시하였다. 닭의 혈청중 IgG함량을 처리별, 시기별로 RID test에 의해 측정한 후 이를 증체량 및 건강상태와 비교한 결과는 다음과 같다. 1. 대조구의 혈청중 IgG함량은 부화 직후에 최고치 (4.26mg/$m\ell$)를 나타내었으며 2주령까지 급격히 감소하여 최소치 (0.87mg/$m\ell$)를 유지하다가 그후에 점차적으로 증가하여, 7주령에는 2.48mg/$m\ell$의 수준을 보였다. 2. 혈청 IgG의 농도와 증체량과의 상관성은 사육전기에는 고도의 유의적인 부의 상관관계를 보였으며 3주령에서 가장 높은 상관계수(r＝-0.423)를 나타냈으며 사육후기에는 정의 상관관계를 나타내어 7주령시의 IgG농도와 3주령시 증체량간에는 r＝＋0.246의 상관계수를 보였다. (p＜0.01) 3. Cul5, Cu25와 ES2O군의 혈청 IgG수준은 2주령에서 대조군에 비하여 낮은 수준을 보이다가 3주령에는 급속히 상승한 반면에 대조군에서는 이와 같은 현상이 1주일 늦게 나타났다. 이는 Cu나 Vit. E와 Se을 혼합 첨가 급여할 경우에는 능동면역의 발달이 대조군보다 1주일 조기에 일어나는 것으로 판단된다. 4. Cu15와 Cu25의 증체량은 대조군보다 높은 수준을 나타내었다. 특히 4주령시 증체율은 대조군에 비하여 4.8%와 4.5%높았다. ES2O군의 증체효과는 없었으며 ES 40군은 대조군보다 유의적으로 낮은 증체유을 보였다. 5. Cul5, Cu25, ES2O, ES4O군은 대조군에 비하여 높은 건강 수준을 유지하였으며 폐사율은 각각 1.9%, 1.9%, 2.9%와 1.0%로써 대조군의 4.8%에 비하여 낮은 수준을 보여 질병에 대한 저항능력이 향상되었다.

• 한국식품영양과학회지
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• 제38권1호
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• pp.47-51
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• 2009

비타민 C 섭취 및 요가가 중년 여성의 총항산화능, 지질과 산화 및 혈중지질에 미치는 영향을 알아보기 위하여 B광역시 H구에 거주하는 중년여성을 대상으로 12주간 실험을 실시하였다. 요가 프로그램은 주 3회, 1일 60분, 운동 강도 RPE $13{\sim}15$로 실시하였다. 비타민 C는 1일 1 g을 섭취시켰다. 12주 후 총항산화능의 변화는 정상군 28.23%, 비타민 C군 30%, 요가군 26.58%, 비타민 C 섭취와 요가군은 43.66%가 증가하였으나 군간 유의적인 차이가 없었다. 지질과산화물가의 변화는 정상군 10%, 비타민 C군 -25%, 요가군은 -32.14%, 비타민 C 섭취와 요가군은 -33.87%로 정상군에 비해 프로그램군이 유의적으로 감소하였으나 프로그램군간의 유의적인 차이는 없었다. 혈중지질농도 변화는 모든군에서 유의적인 차이가 없어 요가 또는 비타민 C 섭취에 따른 지질개선효과를 관찰할 수 없었다. 이상의 결과를 통해 중년여성에게 비타민 C 섭취나 규칙적인 요가 프로그램은 지질과산화물가를 낮춤으로써 체내 산화적 스트레스를 개선하는 효과가 있는 것으로 생각된다.

• 한국식품영양학회지
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• 제6권1호
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• pp.31-36
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• 1993

Strawberry pulp was separated into serum and insoluble pulp by centrifugation and the serum was concentrated in vacuo to five folds at 55~58$^{\circ}C$ and 30~60mmHg. Concentrated strawberry pulp was prepared by mixing of concentrated serum and insoluble pulp. To evaluate the quality changes of straw-berry pulp, color, physicochemical and sensory properties were analyzed after concentration and during 18 weeks storage at -18'2. The results obtained from the study were as follows : during 18 weeks storage at - l8$^{\circ}C$, soluble solid, browning, reducing sugar content were increased and total anthocyanin, vitamin C, apparent viscosity were decreased. The result of sensory evaluation indicated that texture of concentrated pulp was inferior to that of control but flavor, color intensity and overall acceptance were not different from each other.

• Journal of Nutrition and Health
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• 제42권2호
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• pp.107-118
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• 2009

In patients with type 2 diabetes, oxidative stress could be increased by their metabolic changes. Elevated plasma homocysteine is considered as one of markers of enhanced oxidative stress. Due to oxidative stress, some complications like cardiovascular or renal diseases may develop in type 2 diabetes patients. Plasma homocysteine concentration may be increased if folate status were inadequate. Protective effects against oxidative stress may be diminished if the status of anti-oxidative nutrient as vitamin C was poor. It is, therefore, important to maintain adequate status of folate and vitamin C in type 2 diabetes patients. Thus, this study was performed to determine the effects of supplementation of folate and/or ascorbate on blood glycated hemoglobin ($HbA_{1c}$) level, serum concentrations of homocysteine and cholesterol, plasma oxidized low density-lipoprotein (LDL), concentration and plasma glutathione peroxidase (GSH-Px) activity in the patients with type 2 diabetes. A total of 92 type 2 diabetes patients participated voluntarily with written consents. They were divided into one of the four experimental groups; Control (C), Folate-supplemented (F), Ascorbate-supplemented (A), and Folate plus ascorbate-supplemented (FA). The subjects in C were taken placebo, those in F were supplemented 1 mg of folate, those in A received 1,000 mg of ascorbate, and those in FA were given 1 mg of folate plus 1,000 mg of ascorbate daily for 4 weeks. Supplementation of folate or ascorbate resulted to increase serum folate level or plasma ascorbate concentration apparently, respectively. Folate supplementation not ascorbate seemed to decrease plasma concentrations of homocysteine and oxidized LDL and reduce plasma GSH-Px activity. There might not be synergic effect of the supplementation of folate plus ascorbate. The results indicate that oxidative stress in the patients with type 2 diabetes may lower mainly by folate supplementation.

• 대한수의학회지
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• 제13권1호
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• pp.13-16
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• 1973

Sera obtained from 20 milk cows and 20 Korean cattle in group feeding and from 20 Korean cattle from different farmhouses were analyzed for the determination of carotenoid and vitamin A by Carr-Price reaction. The result obtained were as follows: 1. Carotenoid contents of sera from milk cows and Korean cattle in group feeding, and from Korean cattle from different farmhouses were in winter $394.7{\mu}g/100ml$, $157.8{\mu}g/100ml$ and $187.9{\mu}g/100ml$, respectively, and were in summer $735.3{\mu}g/100ml$, $728.2{\mu}g/100ml$ and $760.3{\mu}g/100ml$, respectively. 2. Vitamin A contents of sera from milk cows and Korean cattle in group feeding and from Korean cattle from different farmhouses were in winter 101.2 IU/100 ml, 88.9 IU/100 ml and 48.4 IU/100 ml, respectively, and were in summer 212.0 IU/100 ml, 208.7 IU/100 ml and 208.3 IU/100 ml respectively.

• 한국임상수의학회지
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• 제24권3호
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• pp.453-456
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• 2007

This report described an outbreak of blindness caused by hypovitaminosis A in Hanwoo (Korean native cattle) in Gyeongsangbukdo province, Korea. The diagnosis was based on clinical findings, analysis of diet, and concentration of vitamin A and carotene in serum and/or feedstuff. Thirty eight of 48 cows were found to be affected. The causative diet contained higher levels of crude protein, net energy and crude fat and lower level of total fiber and crude fiber. Surprisingly, vitamin A was not detected in the causative diet. Treatment of vitamin A to Hanwoo that had blindness did not induce further progress of the symptom. Furthermore, there were no additional diseases detected. Based on the observations described above, this case was diagnosed as hypovitiminosis A.

• Journal of Nutrition and Health
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• 제32권8호
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• pp.935-945
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• 1999

The factors affecting bone mineral density (BMD) of 103 rural women aged 30 to 76 years were investigated. Data for food and nutrient intake was obtained by 24-hour recall method. BMD of lumbar spine(L1-L4), femoral neck, ward's triangle and trochanter was measured by XR-series x-ray bone densitometer. Serum was collected and analyzed for total Ca, P and ionized Ca (Ca++)content. Relationship between the factors and BMDs was analyzed by Pearson's correlation coefficient(r) and multiple regression analysis. The results are summarized as follows. 50% of the subjects under 50 years of age($\leq$49 yr group) and 86.4% of the subjects from 50 up($\geq$50yr group) were classified as osteopenia or osteoporosis. Mean body weight, height and BMI were 153.1cm, 59.1kg and 25.0kg/$m^2$ in $\leq$49 yr group and 151.9cm, 55.9kg, and 24.2kg/$m^2$ in $\geq$50 yr group. BMDs of lumbar spines and femurs ranged from 0.84 to 1.05g/$m^2$ and from 0.67 to 1.16g/$m^2$ in $\leq$49 yr group, and ranged from 0.67 to 0.85kg/$m^2$ and from 0.68 to 0.44g/$m^2$ in $\geq$50 yr group, respectively. On the whole, the BMDs were reduced to 83.8 to 94.2% of peck bone mass in $\leq$49 yr group and 55.2 to 78.9% of those in $\geq$50 yr group. Mean daily intake of Ca was much less than the Korean RDA, \67.2% in $\leq$49 yr group and 62.3% in $\geq$50 yr group. The average concentration of total Ca, P and Ca++ in serum were within normal range in both age group. Both age and height were significantly related with BMD in both age group but the relationship tended to be stronger in $\geq$50 yr group than in $\leq$49 yr group. Body weight was also a potent determinant of BMD only in 50 yr group. In $\leq$49 yr group, total food intake was positively related with BMDs of ward's triangle, L1 and L2 and intake of cereals and grain products, sugars and sweets, milk and dairy products was positively related with BMDs measured in this study. On the contrary, intake of eggs, oil and fats were positively related with a few BMDs in 50 yr group. The BMDs were positively affected by intake of energy, protein, carbohydrate, Ca, P and Fe in $\leq$49 yr group and those of protein, fat Ca, P, vitamin B1, vitamin B2 and vitamin C in $\geq$50 yr group. It was noteworthy that serum Ca++ concentration was positively related with BMDs of lumbar spine in boty age groups. According to multiple regression analysis, the four factors, age, body weight, height and BMI additionally accounted for 21% of the variance in BMD of trochanter in $\leq$49 yr group and only two factors, age and C a intake accounted for 38% of that of femoral neck in $\geq$50 yr group. Further investigation is necessary to make sure of the relations between BMD and serum Ca++ level.

• 대한지역사회영양학회지
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• 제13권2호
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• pp.263-275
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• 2008

Impaired fasting glucose (IFG) is one of significant risk factors of developing diabetes. The persons with IFG are, thus, an important target group for primary prevention of diabetes. It is well known that plasma homocysteine concentration may be increased in poor folate nutritional status. Elevated level of plasma homocysteine is considered as a marker of enhanced oxidative stress. In addition, the protective effect against oxidative stress may be diminished in poor antioxidative nutrient status as vitamin C. It is, therefore, important to maintain adequate nutritional status of folate and vitamin C in the patients with type 2 diabetes or IFG. This study was performed to determine the effects of supplementation of folic acid or vitamin C on plasma concentrations of homocysteine, oxidized LDL, and lipids and on the activity of plasma anti-oxidative enzyme in patients with IFG. A total of 97 patients with IFG were participated voluntarily with written consents. They were divided into one of the four experimental groups; Control (C), Folatesupplemented (F), Ascorbate-supplemented (A), and Folate plus ascorbate-supplemented (FA). The subjects in C were taken placebo, those in F were supplemented 1 mg of folate, those in A were received 1,000 mg of vitamin C, and those in FA were given 1 mg of folate plus 1,000 mg of vitamin C daily for 4 weeks. No change in plasma concentrations of vitamin C, lipids, and oxidized LDL and the activity of GSH-Px were observed in vitamin C-supplemented group (A + FA) and folate-supplemented group (F + FA) compared to the placebo group (C + A). Only the folate-supplemented group (F + FA) had significantly increased average serum folate concentration and lowered plasma homocysteine concentration compared to the placebo group (C + A). Thus, it should be recommended the patients with IFG to increase folate intake through diets and, if it is not sufficient, to take folic acid supplements to prevent the development of complications induced by hyperhomocysteinemia as well as oxidative stress.

• Allergy, Asthma & Respiratory Disease
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• 제6권6호
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• pp.284-289
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• 2018

Purpose: Vitamin D plays an important role in calcium homeostasis and bone metabolism. It is associated with various diseases such as cardiovascular, immune, allergic and infectious disease. The aim of this study was to investigate the difference in clinical manifestations according to the concentration of vitamin D in mild bronchiolitis. Methods: We performed a retrospective review of medical records of patients with mild bronchiolitis from November 2016 to April 2017 in Daegu Fatima Hospital. Mild bronchiolitis was classified by the modified Tal's score method. Patients were divided into 2 groups according to a 25-hydroxyvitamin D level of 20 ng/mL. We analyzed the clinical characteristics and laboratory data from the 2 groups. Results: Of the 64 patients, 19 were included in the deficiency group and 45 in the normal group. Vitamin D levels were $11.7{\pm}4.9ng/mL$ in the deficiency group and $28.8{\pm}5.0ng/mL$ in the normal group. There were no differences in clinical features between both groups. However, the vitamin D deficiency group had significantly longer hospitalization than the normal group ($6.78{\pm}2.74$ days vs. $5.3{\pm}1.7$ days, P=0.045). In the deficiency group, the incidence of previous respiratory diseases was significantly higher (P=0.001). No significant difference in blood and respiratory virus tests was observed. Conclusion: Low vitamin D levels in mild bronchiolitis were associated with longer hospitalization and prior respiratory disease. Vitamin D may affect the course of mild bronchiolitis.

• 동아시아식생활학회지
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• 제10권6호
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• pp.495-506
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• 2000

The purpose of this study was to assess the nutritional status of iron and magnesium and the effect of von supplementation during 8 weeks(from 20 to 28 weeks of gestation) on serum iron and magnesium status of 31 pregnant women in Kyunsin area. The age, weight, and height of the subjects before pregnancy were investigated by questionnaires. At 20 and 28 weeks of gestation, data for food and nutrient intake were obtained by questionnaires and serum sample was obtained. According to the frequency of iron supplementation, subjects were divided into two groups(4$\geq$/wk) The mean iron supplementation of 5 $\geq$/wk group(63.mg/day) was significantly higher than 4$_2$ intakes were much less than the Korean RDA. Especially, calcium, iron and magnesium intakes showed half the levels compared with Korean RDA. At 28 weeks of gestation the serum total protein(p<0.001), albumin(p<0.01) and globulin(p<0.001) were significantly decreased. Total iron binding capacity(TIBC) was significantly increased(P<0.001), but serum ferritin(p<0.01) and magnesium(p<0.01) concentrations were significantly decreased. However, even 28 weeks of gestation 5$\geq$/wk group showed higher serum iron and ferritin concentration and lower TIBC than 4$\geq$/wk group. Therefore, iron supplementation should be conducted with concerning the mineral balance like magnesium.