• Title/Summary/Keyword: Separation failure

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A Study on Trauma Experiences among Korean Adults based on Conditional probability of PTSD symptoms (PTSD 증상의 조건비율에 근거한 한국 성인의 트라우마 경험에 관한 연구)

  • Kim, Ji-Yun;Lee, Dong-Hun;Kim, Si-Hyeong
    • Korean Journal of Culture and Social Issue
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    • v.24 no.3
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    • pp.365-383
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    • 2018
  • In this study, to search for events that cause high levels of PTSD symptoms, traumatic events are classified into 'criterion events' that meet DSM-IV-TR criteria and 'life stresssful events', conditional probability of PTSD was confirmed. From a sample of 1,000 adults residing in South Korea, 998 statistically relevant samples were extracted. Criterion events include cases of 'sexual harassment before age 16', 'sightings of other accidents', 'rape before 16', 'domestic violence before 16', 'disaster', 'traffic accidents', 'other accidents'. Life stressful events appeared to be 'legal arrest or detention(person and family)', 'parental separation or divorce', 'failure or despair causing serious stress', 'extreme conflict with family or frequent quarrels'. Among the demographic characteristics, age, marital status, religion were found to affect PTSD symptoms. The implications and limitations of these results are discussed.

Anti-Menopausal Effect of Heat-Killed Bifidobacterium breve HDB7040 via Estrogen Receptor-Selective Modulation in MCF-7 Cells and Ovariectomized Rats

  • Hyeon Jeong Kim;Kyung Min Kim;Min-Kyu Yun;Duseong Kim;Johann Sohn;Ji-Won Song;Seunghun Lee
    • Journal of Microbiology and Biotechnology
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    • v.34 no.8
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    • pp.1580-1591
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    • 2024
  • Menopause is induced by spontaneous ovarian failure and leads to life quality deterioration with various irritating symptoms. Hormonal treatment can alleviate these symptoms, but long-term treatment is closely associated with breast and uterine cancer, and stroke. Therefore, developing alternative therapies with novel anti-menopausal substances and improved safety is needed. In our study, heat-killed Bifidobacterium breve HDB7040 significantly promoted MCF-7 cell proliferation in a dose-dependent manner under estrogen-free conditions, similar to 17β-estradiol. This strain also triggered ESR2 expression, but not ESR1, in MCF-7 cells. Moreover, administrating HDB7040 to ovariectomized (OVX) Sprague-Dawley (SD) female rats reduced estrogen deficiency-induced weight gain, fat mass, blood triglyceride, and total cholesterol levels. It also recovered collapsed trabecular microstructure by improving trabecular morphometric parameters (bone mineral density, bone volume per tissue volume, trabecular number, and trabecular separation) and decreasing blood alkaline phosphatase levels with no significant changes in uterine size and blood estradiol. HDB7040 also significantly regulated the expression of Tff1, Pgr, and Esr2, but not Esr1 in uteri of OVX rats. Heat-killed B. breve HDB7040 exerts an anti-menopausal effect via the specific regulation of ERβ in vitro and in vivo, suggesting its potential as a novel substance for improving and treating menopausal syndrome.

Errors in the Winter Temperature Response to ENSO over North America in Seasonal Forecast Models

  • Seon Tae Kim;Yun-Young Lee;Ji-Hyun Oh;A-Young Lim
    • Journal of Climate Change Research
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    • v.34 no.20
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    • pp.8257-8271
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    • 2021
  • This study presents the ability of seasonal forecast models to represent the observed midlatitude teleconnection associated with El Niño-Southern Oscillation (ENSO) events over the North American region for the winter months of December, January, and February. Further, the impacts of the associated errors on regional forecast performance for winter temperatures are evaluated, with a focus on 1-month-lead-time forecasts. In most models, there exists a strong linear relationship of temperature anomalies with ENSO, and, thus, a clear anomaly sign separation between both ENSO phases persists throughout the winter, whereas linear relationships are weak in observations. This leads to a difference in the temperature forecast performance between the two ENSO phases. Forecast verification scores show that the winter-season warming events during El Niño in northern North America are more correctly forecast in the models than the cooling events during La Niña and that the winter-season cooling events during El Niño in southern North America are also more correctly forecast in the models than warming events during La Niña. One possible reason for this result is that the remote atmospheric teleconnection pattern in the models is almost linear or symmetric between the El Niño and La Niña phases. The strong linear atmospheric teleconnection appears to be associated with the models' failure in simulating the westward shift of the tropical Pacific Ocean rainfall response for the La Niña phase as compared with that for the El Niño phase, which is attributed to the warmer central tropical Pacific in the models. This study highlights that understanding how the predictive performance of climate models varies according to El Niño or La Niña phases is very important when utilizing predictive information from seasonal forecast models.

Identification of Bovine Pregnancy-Specific Whey Proteins using Two-Dimensional Gel Electrophoresis

  • Han, Rong-Xun;Choi, Su-Min;Kim, Myung-Youn;Quan, Yan Shi;Kim, Baek-Chul;Diao, Yun Fei;Koqani, Reza;Park, Chang-Sik;Jin, Dong-Il
    • Reproductive and Developmental Biology
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    • v.32 no.4
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    • pp.255-261
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    • 2008
  • The early diagnosis of bovine pregnancy is an essential component of successful reproductive planning on farms, because lack of bovine pregnancy over the long term results in reproductive failure and low milk yield-the latter of which is a special concern on dairy farms. This study was designed to identify early pregnancy-specific whey proteins in bovine, by comparing milk samples collected from cattle during pregnancy (Days 30 and 50) and from non-pregnant cattle. In this study, differentially expressed proteins in five pregnant and five non-pregnant Holstein dairy cattle were investigated and compared, using proteomics analysis. The first dimension was applied to a pH $3.0{\sim}10.0$ strip, by loading a 2-mg milk protein sample. After the second-dimension separation was performed, the gels were stained with colloidal Coomassie brilliant blue. The stained gels were scanned and the images were analyzed, to detect variations in protein spots between non-pregnant and pregnant cattle milk protein spots, using ImageMaster, this was followed by analysis with MALDI TOF-MS. Analysis of the 2-DE gel image resulted in a total of approximately $500{\sim}600$ protein spots, of which 12 spots were differentially expressed, six spots were up-regulated, and four spots were down-regulated; two spots were identified as pregnancy-specific proteins. These proteins were identified as lactoferrin, NA-DH dehydrogenase subunit 2, albumin, serum albumin precursor and transferrin. Our results via 2-D PAGE analysis revealed composite profiles of several milk proteins related to early bovine pregnancy, implying the possible use of these milk proteins in the early detection of bovine pregnancy.

The Stability Analysis of Near Parallel Tunnels Pillar at Multi-layered Soil with Shallow Depth by Numerical Analysis (수치해석에 의한 저토피 다층지반에서 근접 병설터널 필라의 안정성 분석)

  • Lim, Hyungmin;Son, Kwangrok
    • Journal of the Korean GEO-environmental Society
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    • v.15 no.1
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    • pp.53-62
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    • 2014
  • In Korea, in general, separation distance between existing parallel tunnels was set at two to five times as distant as the diameter of the tunnels according to ground conditions. Recently, however, actual applicability of closely spaced parallel tunnels whose distance between tunnel centers was shorter than the diameter has increased due to environmental damages resulting from massive cutting, restriction in purchase of required land, and maintenance of linear continuity. In particular, when the pillar width of tunnel decreases, the safety of pillars affects behaviors of the tunnel and therefore the need for diverse relevant studies has emerged. However, research so far has been largely confined to analysis of behavior characteristics of pillars, or parameters affecting design, and actually applicable and quantitative data have not been presented. Accordingly, in order to present a stability evaluation method which may maximally reflect construction conditions of spots, this study reflected topographical and stratigraphic characteristics of the portal part with the highest closeness between the tunnels, simulated multi-layer conditions with rock mass and complete weathering, and assessed the degree of effect the stability of pillars had on the entire tunnels through numerical analysis according to changes in pillar width by ground strength. This study also presented composite analysis result on ground surface settlement rates, interference volume rates, and average strength to stress and a formula, which may be applicable to actual work, to evaluate safety rates of closely spaced parallel tunnel pillars and minimum pillar width by ground strength based on failure criteria by Hoek-Brown (1980).

A Study for Lifespan Prediction of Expansion by Temperature Status (온도상태에 따른 신축관 이음의 수명예측에 관한 연구)

  • Oh, Jung-Soo;Lee, Bong-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.10
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    • pp.424-429
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    • 2018
  • In this study, an expansion joint that is susceptible to waterhammer was tested for its vibration durability. The operation data for the hydraulic actuator was the expansion length of the expansion joint when the waterhammer occurred. In the case of the vibration durability test, the internal temperature status of the expansion joint was assumed to be a stress factor and a lifespan prediction model was assumed to follow the Arrhenius model. A test was carried out by increasing the internal temperature status at $30^{\circ}C$, $50^{\circ}C$, and $65^{\circ}C$. By a linear transformation of the lifespan data for each temperature, a constant value and activation energy coefficient was induced for the Arrhenius equation and verified by comparing the value of a lifetime prediction model with the experimental value at $85^{\circ}C$. The failure modes of the ongoing or finished test were leakage, bellows separation, and internal deformation. In the future, a composite lifespan prediction model, including two more stress factors, will be developed.

An Experimental Study on the Flexural Behavior of RC Beams Strengthened with High-Strength Bars(1) (고장력 인장봉으로 보강된 RC보의 휨거동에 관한 실험적 연구(1))

  • Shin, Kyung-Jae;Kwak, Myong-Keun;Heo, Byung-Wook;Na, Jung-Min;Oh, Young-Suk
    • Journal of the Korea Concrete Institute
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    • v.18 no.4 s.94
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    • pp.527-534
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    • 2006
  • This paper outlines a new strengthening technique for concrete beams using externally unbended high-strength bars. The advantages of proposed method lie in speed and simplicity of construction compared to the alternative strengthening method. Externally unbended reinforcement retains many of the advantages over external unbended prestressed tendons. It eliminates time consuming stressing operations. Clearance requirements around anchorages are reduced as access is not required for prestressing jacks. Test results of eight specimens on reinforced concrete beams using different reinforcement materials such as carbon fiber sheet, steel plate and high-tension bar are reported. The beam strengthened by carbon fiber sheet showed a brittle failure mode due to the separation of fiber. As a result of draped profile of external bar, the maximum strength of the beam were increased by up to 212 percent and the deflections were reduced by up to 65 percent. Test results show that the beams reinforced with high-tension bar are superior to reference specimens, especially for the strength and deformation capacity.

A Study on Mechanical Interfacial Properties of Copper-plated Carbon Fibers/Epoxy Resin Composites (구리도금된 탄소섬유/에폭시 수지 복합재료의 기계적 계면 특성에 관한 연구)

  • Hong, Myung-Sun;Bae, Kyong-Min;Choi, Woong-Ki;Lee, Hae-Seong;Park, Soo-Jin;An, Kay-Hyeok;Kim, Byung-Joo
    • Applied Chemistry for Engineering
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    • v.23 no.3
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    • pp.313-319
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    • 2012
  • In this work, the electroplating of copper was introduced on PAN-based carbon fibers for the enhancement of mechanical interfacial strength of carbon fibers-reinforced composites. The surface properties of carbon fibers were determined by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and contact angle measurements. Its mechanical interfacial properties of the composites were studied by interlaminar shear strength (ILSS) and critical stress intensity factor ($K_{IC}$). From the results, it was found that the mechanical interfacial properties of Cu-plated carbon fibers-reinforced composites (Cu-CFRPs) enhanced with increasing the Cu plating time, Cu content and COOH group up to Cu-CFRP-30. However, the mechanical interfacial properties of the Cu-CFRPs decreased dramatically in the excessively Cu-plated CFRPs sample. In conclusion, the presence of Cu particles on carbon fiber surfaces can be a key factor to determine the mechanical interfacial properties of the Cu-CFRPs, but the excessive Cu content can lead the failure due to the interfacial separation between fibers and matrices in this system.

An Experimental Study on Reinforcement Method for Reuse of Onshore Wind Turbine Spread Footing Foundations (육상풍력터빈 확대기초의 재사용을 위한 보강방법에 관한 실험적 연구)

  • Song, Sung Hoon;Jeong, Youn Ju;Park, Min Su;Kim, Jeong Soo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.41 no.1
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    • pp.1-11
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    • 2021
  • In order to reuse existing onshore turbine foundations, it is important to redesign and reinforce the existing foundations according to the upgraded tower diameter and turbine load. In the present study, a slab extension reinforcement method and structure details of an anchorage part were examined in consideration of the reuse of spread footings, which are the most widely used foundation type in onshore wind turbine foundations. Experiments were conducted to evaluate the load resistance performance of a reinforced spread footing according to structure details of an anchorage part. The results showed that (1) the strength of an anchorage part could be increased by more than 30 % by adding reinforcement bars in the anchorage part, (2) pile-sleeves attached to an anchor ring contributed to an increase in rotational stiffness by preventing shear slip behavior between the anchor ring and the concrete, and (3) slab connectors contributed to an increase in the strength and deformation capacity by preventing the separation of new and old concrete slabs.

Study of Structural Stability and Seismic Performances of 4-Way Sway Prevention Brace (4방향흔들림방지버팀대의 구조 안정성 및 내진 성능 연구)

  • O, Soo Un;Lee, Hang Jun;Choa, Sung Hoon
    • Journal of the Society of Disaster Information
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    • v.18 no.3
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    • pp.646-659
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    • 2022
  • Purpose: In this study, we developed a 4-way sway prevention brace that efficiently reduces the installation area and has excellent stability and seismic performance compared to the conventionl sway prevention brace used in existing firefighting facilities. The performance and reliability of the developed 4-way way prevention brace were analyzed by the tensile, compression tests and seismic tests. Method: As the static test, 4-way sway prevention braces were installed on the horizontal and vertical pipes to perform the tensile and compression tests based on the KFI certification standard and the maximum movement was measured at the rated load. As a dynamic test, 4-way sway prevention braces were installed in the pipes filled with water, and the test response spectrum to the input excitation wave were measured through the acceleration sensors. After the seismic tests, separation, failure, and local deformation of the pipes, and 4-way sway prevention braces were not observed. Result: The results of the tensile and compression tests indicated that the maximum movement of the pipe during tension and compression was 50% to 70% or less compared to the certification values, indicating that the performances of the 4-way sway prevention braces were very excellent. The results of the the seismic tests indicated that the test response spectrum of the 4-way sway prevention braces is within the required response spectrum. Conclusion: In this study, it was found that the 4-way sway prevention braces satisfied the KFI certification standard and were superior compared to the existing sway prevention brace in terms of the stability, cost, and installation area.