• Archives of Pharmacal Research
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• v.22 no.6
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• pp.614-618
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• 1999

A reversed-phase high-performace liquid chromatographic method was developed to determine the optical purity of metoprolol enantiomers. The enantiomers were converted to diastereomeric derivatives using (-)-menthyl chloroformate reagent. Separation of the enantiomers as diastereomers was achieved by reversed-phase HPLC within 30 min using Inertsil C8 column. This method allowed determination of 0.05% of either enantiomer in the presence of its stereoisomer and method validation showed adequate linearity over the required range. Owing to the reaction condition during the derivatization with (-)-menthyl chloroformate, the possibility of racemization had to be established. Different ratios of (S)-(-)-metoprolol and (R)-(+)-metoprolol were prepared. Enantiomeric separation of these mixtures took place on a chiralcel OD column or, after derivatization with (-)-menthyl chloroformate, on a C8 column. The results form the these two independent separation systems were compared with trace racemization and were in very good agreement. No racemization was found during the experiment.

• Membrane Journal
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• v.31 no.6
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• pp.426-433
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• 2021

In this study, a novel material polyketone (PK) was chosen and PK micro/nano fiber membranes were fabricated via electrospinning method under various conditions. After that, the potential application in oil-water separation was thoroughly investigated. The surface of microfiber membrane formed under high humidity especially became much rougher than that formed under low humidity. When salt was added to the spinning solution, the diameter of fibers was reduced up to 90% and the nanofiber membranes could be formed. The oil/water emulsions were prepared and separated under gravity condition using the manufactured rPK-LNC and PK-H membranes. The separation characteristics was evaluated by measuring total organic carbon (TOC) and turbidity. Meanwhile, the changes in the physical properties of fiber membranes under various conditions and with or without salt, as well as the changes in oil water separation characteristics were also studied.

• Aerospace Engineering and Technology
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• v.2 no.2
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• pp.83-88
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• 2003

Satellite mounted on the launch vehicles experiences several environmental heating, such as direct solar flux, Earth IR, Albedo, and free molecular heating during faring jettison-separation launch stage. So, the most outer payload box of satellite is under the worst hot condition. The thermal governing equation is reduced into 1st order ordinary differential equation and analytic solution is acquired if payload box is assumed as a single lumped mass. Applying the analytic solution, we can predict the temperature increase of payload box experienced the worst hot condition, easily.

• Journal of Korean Society of Water and Wastewater
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• v.8 no.1
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• pp.27-33
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• 1994

With the rapid industrialization, an ever-increasing quantity and kind of new organic compounds pose environmental problems due to their toxicity and physiological effect. However, research on the biodegradation of these compounds under anaerobic condition is very limited inspite of its efficiency and economical advantage. In this research, the pH effect on the ring cleavage of phenol under anaerobic condition was investigated, and the theory of phase separation was applied to the degradation of phenol for investigating the role of acidogenic bacteria. Results, obtained from biochemical methane potential(BMP) assay for 15.5 days of incubation, showed that acidic condition was more desirable for phenol degradation than alkaline condition. By both unacclimated methanogenic granular sludge and two mixed cultures, phenol was completely removed within six weeks of incubation with a gas conversion rate of over 86% of theoretical one. However, phenol was not degraded by unacclimated acidogenic culture, and thus it is considered as a syntrophic substrate. In case of phase separated biochemical methane potential(PSBMP) assay, in which acidogenic and methanogenic culture were seeded separately and consecutively, those that had been subjected to normal acidogens for 3 to 4 weeks showed higher gas production than those seeded with sterile or frozen culture.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.3
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• pp.331-337
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• 2014

Purpose: This is a comparative experimental study on the amount of phoria by the removal time of binocular fusion. In this study, three tests were used for phoria test like Howell test, Thorington test and developed 3D polarizing test. Methods: In this study, it was considered the removal time of binocular fusion for measuring phoria. The three methods were used for measuring quantity of phoria: Howell test, Thorington test and developed 3D Polarizing test. The measurements progressed quickly to avoid eye-strain. So we designed the test charts for marking 3D display modules and the apparatus inserted lenses, like Maddox lens and prism, which are compatible with three phoria tests. The phoria at the moment separation was measured when the binocular fusion was broken through the apparatus and the that at the stable separation was measured when activity of the separated two images like indicated box and figure on horizontal axis stopped. Results: There were statistically significant difference between quantity of phoria at moment separation and that at stable separation. Amount of phoria at moment separation was relatively larger than amount of that at stable separation. In result in exophoria, the quantity of phoria at moment separation was higher than that at stable separation, and in phoria measured by developed 3D polarizing test, it shows the similar results at two condition. Conclusions: For exophoria, the amount of phoria at moment separation of binocular fusion was relatively larger than that at stable separation. The amount of difference between phoria values at moment separation and that at stable separation was alike among three phoria tests. Usually in working, there is no distinction between moment separation and stable separation. But there were definitely the difference between two ways to separate binocular fusion. Therefore, it is need for writing on prescription test name for measuring phoria and condition of separation of binocular fusion.

• Membrane Journal
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• v.13 no.4
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• pp.219-228
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• 2003

This study was carried to investigate the effect of humic acid and kaloin which cause the turbidity and organic substance component for optimization of drinking water treatment process using the membrane separation. Also we were ovserved the optimum operating condition which flux was stabilized, while specific resistance value in membrane was minimized. As the result, the membrane separation was operated at low specific resistance value with the increase of the pressure. And then, cake load decreased by high velocity with the increase of the linear velocity, and the tendency in which specific resistance value and flux increased. Therefore, we confirmed the optimum operating condition as pressure $2.0 kgf/cm^2,$ 0.92 m/sec linear velocity.

• Journal of Ocean Engineering and Technology
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• v.24 no.4
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• pp.13-22
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• 2010

While a caisson used for breakwater is carried by a floating dock, accompanying stability problem by its existing motions in the dock is quite important and should be pre-checked against sea environmental condition. In the stability analysis, the acceleration, velocity, angle of roll and pitch motions are important to calculate frictional force and separation force. If separation force becomes bigger than frictional force, serious collision may be occurred between caisson and floating dock. In this study, stability evaluation during the transportation of a caisson on floating dock for breakwater was performed by using a commercial program, HydroD and CHARM3D/HARP.

• Hwankyungkyoyuk
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• v.14 no.1
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• pp.19-31
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• 2001

This study examined the effect of environmental alteration and prompts on recycling behavior. An A-B-BC with a control condition design was employed. Subjects in this study were college students, professors, and employees at a university building. After a baseline phase, environmental alteration was I effect in the next phase and both environmental alteration and prompts were in effect in the final phase for the control condition. The environmental alteration consisted of providing four separation containers for the paper cups, cans recyclable paper, and the disposable on each floor in the building. The prompts consisted of providing the information about the importance of environmental preservation and how to separate the materials in the appropriate containers using an information board and pamphlets. The dependent variables were (1) the number of cans collected in can container, (2) the number of paper cups collected in cup container, (3) the rate of correct separation of cans, (4) the rate of correct separation of paper cups, and (5) the weight of disposable. The rates of correct separations of cans and paper cups were obtained by calculating the percentage of thenumber of recyclable cans and paper cups in the corresponding containers. The results indicated that environmental alteration had positive effects on all the dependent variables. Also, when the prompts were added to the environmental alteration, the incremental effect of the prompts was demonstrated. The implications and limitations of theses findings were discussed and the direction of future studies was also proposed.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.33 no.8
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• pp.42-49
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• 2005

A new blockage correction method has been developed for the wall interference correction of closed test-section subsonic wind tunnels based on the nonlinear relationship between separation blockage and separation drag. This method can be applied continuously from the linear lift-slope region to the highly nonlinear post-stall region by on-line processing. The present method was validated by comparing the results with a classical method based on the test results of a bluff body and a measured-boundary-condition method. It was shown that the present method is in good agreement with the measured-boundary-condition method, enabling better wall corrections than the bluff body method in both near-stall and post-stall regions.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.77.1-77.1
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• 2016

We investigate the properties and detection conditions for the planetary caustic perturbation of close-separation planets. To find the properties of the planetary caustic perturbation, we construct deviation maps by subtracting the single-lensing magnification of the lens star from the planetary lensing magnification for various lensing parameters. We find that each deviation area of the positive and negative perturbations disappears at the same normalized source radius according to a given deviation threshold regardless of mass ratio but disappears at a different normalized source radius according to the separation. We also estimate the upper limit of the normalized source radius to detect the planetary caustic perturbation. We find simple relations between the upper limit of the normalized source radius and the lensing parameters. From the relations, we obtain an analytic condition for the detection limit of the planet, and which show that we can sufficiently discover a planet with the mass of sub-Earth for typical microlensing events. Therefore, we expect to add the number of low-mass planets in the next-generation microlensing experiments and conclude that our detection condition of the planet can be used as a important criteria for maximal planet detections considering the source type and the photometric accuracy.