• Archives of Pharmacal Research
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• v.19 no.1
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• pp.77-78
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• 1996

• Archives of Pharmacal Research
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• v.27 no.10
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• pp.1034-1036
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• 2004

Four compounds were isolated from Salicornia herbacea by repeated column chromatography. Their structures were identified as ${\beta}$-sitosterol (1), stigmasterol (2), uracil (3), and isorhamnetin-3-O-${\beta}$-D-glucopyranoside (4) by spectral analysis and comparison with the published data.

• Archives of Pharmacal Research
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• v.10 no.2
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• pp.132-141
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• 1987

New triterpenoid saponins, ilexosides A, D, E, J, K and O have been isolated form the root of Ilex pubescens. Chemical and spectroscopic studies have established their structures as shown in formulae 1, 2, 8, 11, 3, 4 and 5.

• Archives of Pharmacal Research
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• v.10 no.2
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• pp.115-120
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• 1987

Methanol extract of Ilex pubescens roots prolonged bleeding time threefold, and inhibited the generation of malondialdehyde released during platelet aggregation inducted by thrombin. Through several purification procedures, its saponin, named ilexoside, was proved to be responsible for the antithrombotic activities of the plant. Ilexosides A, -D and -J and 24-carboxypomolic acid showed strong inhibitory activities on platelet aggregation induced by thrombin.

• Archives of Pharmacal Research
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• v.10 no.2
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• pp.121-131
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• 1987

Four triterpenoids were isolated from the roots of Ilex pubescens : two new triterpenoids named pubescenolic acid (I) and pubescenic acid (II), and two known triterpenoids ilexolic acid (III) and oleanolic acid (IV). Chemical and spectroscopic studies have established I and II as 20-epipomolic acid and 24-carboxypomolic acid, repectively.

• Archives of Pharmacal Research
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• v.8 no.4
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• pp.229-236
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• 1985

Oxidation of presenegenin dimethyl ester triacetate with chromium trioxide in acetic acid yielded two compounds, 11-ketone (IV) and 12-ketone (IV) derivatives. The latter was a main product. On mild alkaline hydrolysis, IV afforded 11-keto-presenegenin dimethyl ester (V), mp 232-$234^{\circ}$, $C_{32}H_{48}O_{8}$, whereas VI did 12-keto-presenegenin dimethyl ester 12, 27-hemiketal (VIII), mp 240-$242^{\circ}$, $C_{32}H_{50}O_{8}$.

• Archives of Pharmacal Research
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• v.3 no.2
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• pp.75-78
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• 1980

Potential antinumor activity of sixteen Korean medicinal plants was tested against leukemia SN 36, murine tomor model. Survival studies by measuring life span indicated that Morus alba (Moraceae), Verbascum phlomoides (Scrophulariaceae), Curcuma longa (Zingbieraceae), Torilis japonica (Umbelliferae), Bupleurum falcatum (Umbelliferae) and Codonopsis pilosula (Campanulaceae) exhibited significant antitumor activity with the dose-schedule employed in the experiment. Methanol (70%) extracts of Platycodon gradiflorum (Campanulaceae), Bupleurum longeradiatum (Umbelliferae) and Asiasarum sieboldii (Aristolochiaceae) showed rather potent toxicity.

• Archives of Pharmacal Research
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• v.3 no.2
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• pp.79-84
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• 1980

Eight species of the genus Angelica in Korea were examined for the activity of affecting drug metabolism and for the presence of coumarins. The results showed that various parts, especially roots and fruits of Angelica plants had strong effects on drug metabolism and that they contained various derivatives of coumarins.

• Archives of Pharmacal Research
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• v.11 no.2
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• pp.159-162
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• 1988

From the root bark of Acanithopanax koreanum, two polyacetylene compounds and one lignan compound were isolated and identified as falcarinon, falcarindiol and ariensin. Furthermore the steam bark also afforded methyl n-hexacosanoate, methyl linoleate and coniferin.

• Archives of Pharmacal Research
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• v.6 no.1
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• pp.29-33
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• 1983

From the roots of Pandia siamensis, D-mannitol, a mixture of .betha.-sitosterol and campesterol, oleanolic acid acetate, oleanolic acid-3-.alpha.-L-arabino side and mesembryanthemoidigenic acid as a sapogenin were isolated and characterized.