• 한국의료질향상학회지
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• 제27권1호
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• pp.20-25
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• 2021

Purpose: The ability to access clinical trials for cancer treatment is important. This study investigated whether regional differences exist in oncologic clinical trial protocols conducted in South Korea. Methods: Records of all approved oncologic clinical trials conducted in 2019 were downloaded from the Republic of Korea Ministry of Food and Drug Safety. The study covered Seoul, the capital area, other metropolitan cities, and provincial areas. Descriptive statistics summarized the distribution patterns of clinical trials by region. Results: A total of 202 oncologic clinical trials were conducted in 63 institutions in 2019. Of these protocols, 186 (92%) were available in Seoul, 120 (59%) in the capital area, 64 (32%) in metropolitan cities, and 66 (33%) in provincial areas. More regional differences in protocol availability were observed in domestic trials, investigator-initiated trials, phase 1 and 2 trials, and smaller-scale trials. Conclusion: Most oncologic clinical trials were conducted in medical institutions located in Seoul, with the rest conducted in the capital area, metropolitan cities, and provincial areas. The findings reveal clear differences in protocol availability between Seoul and the other regions. Measures designed to improve geographical access to oncologic clinical trials may be needed given their growing importance in cancer treatment.

• 한국환경보건학회지
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• 제25권3호
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• pp.51-57
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• 1999

This study was carried out to investigate the concentrations of Ni, Cr and Cu, to analyze the correlations among those, and between concentrations and traffic volumes by type of car in roadside ambient air at Chongro-, Chungkechon- and Kangnam terminal- area in Seoul from October 1st to October 31st in 1997. The results were as follows ; 1. The means of concentrations of Ni in roadside ambient air were 34.1, 25.1 and 23.6 ng/m$^3$ at Chungkechon, Kangnam terminal and Chongro area, respectively. The highest concentrations of Ni by time were 26.8 in the evening, 45.5 in the evening and 49.4 ng/m$^3$ in the forenoon at Chongro, Chungkechon and Kangnam terminal area, respectively. 2. The means of concentrations of Cr in road side ambient air were 97.7, 80.1 and 70.9 ng/m$^3$ at Chong, Chungkechon and Kangnam terminal area, respectively. The highest concentrations of Cu by time were 205.3 in the evening, 114.4 in the evening and 92.3 ng/m$^3$ in the forenoon at Chongro, Chungkechon and Kangnam terminal area, respectively. 4. The tendencies of concentrations of Ni and Cr by time were similar to each other. Especially, at Kangnam terminal area, correlation coefficients between concentrations of Ni and Cr and the traffic volume of bus were high(r=0.997,0.975). 5. The tendency of concentration of Cu and the traffic volume of passenger car at each area were high(r=0.832, 0.968) 6. Correlation coefficients between Cu and Zn, and between Ni and Cr were 0.762 and 0.842, respectively. This means that the possibility of co-existence of Cu-Zn or Ni-Cr is very high.

• 한국콘텐츠학회논문지
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• 제16권7호
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• pp.348-358
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• 2016

본 연구에서는 수도권 인구를 분석하여 도시 성장주기 변화를 밝히고, 각 권역별 특성을 파악해보고자 한다. 이를 위해 최근 일본에서 활발히 연구되고 있는 도시 성장주기 방법론인 ROXY 지수를 적용하였다. 분석결과, 중부지역, 남부지역, 수도권 전체적인 측면에서는 집중화 가속단계로 옮겨가려 하고 있으며, 교외화 단계에서 새로운 단계인 도심회귀로 전환될 가능성이 높은 것으로 나타났다. 또한, 교외지역인 북부지역과 동부지역에서는 현재 탈중심화 가속단계로 진행되었고 앞으로 탈집중화 감속단계로 전환될 것으로 예측되었다. 이를 통한 시사점으로는 수도권에서도 도시순환주기의 변화방향과 속도를 연계해 지역정비에 관한 정책대응을 실시하는 것이 필요할 것으로 판단된다. 본 연구의 결과는 향후 장기적인 수도권의 성장 및 쇠퇴를 가늠해 볼 수 있는 기초자료로 활용될 수 있을 것이다.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
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• pp.426-429
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• 2007

One of the widely used applications of remote sensing studies is environmental change detection and biodiversity conservation. The study area Hustai Mountain is situated in the transition zone between the Siberian taiga forest and Central Mongolian arid steppe. Hustai National Park carries out one of several reintroduction programs of takhi (wild horse or Equus ferus przewalskii) from various zoos in the world and it represents one of a few textbook examples of successful reintroduction of an animal extinct in the wild. In this paper we describe the results of an analysis on the change of remaining forest area over the 7-year period since Hustai Mountain was designated as a protected area for reintroduction to wild horses. Today the forested area covers approximately 5% of the Hustai National Park, mostly the north-facing slopes above 1400 m altitude. Birch (Betula platyphylla) and aspen (Populus tremula) trees are predominant in the forest. We used Landsat ETM+ images from two different years and multi temporal MODIS NDVI data. Land types were determined by supervised classification methods (Maximum Likelihood algorithm) verified with ground-truthing data and the Land Change Modeler (LCM) which was developed by Clark Labs. Forested area was classified into three different land types, namely the forest land, mountain meadow and mountain steppe. The study results illustrate that the remaining birch forest has rapidly changed to fragmented forest land and to open areas. Underlying causes for such a rapid change during the 15-year period may be manifold. However, the responsible factors appear to be the drying off and outbreak of forest pest species (such as gypsy moth or Lymantria dispar) in the area.

• Elastomers and Composites
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• 제49권4호
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• pp.275-283
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• 2014

건축용 접착제로 활용되고 있는 부틸고무는 주로 시트의 형태로 사용된다. 본 연구에서는 컴퓨터 해석을 통해 부틸고무 시트 압출용 다이를 설계하였다. 압출용 다이의 내부는 크게 매니폴드와 랜드로 나뉜다. 매니폴드는 다이중앙에서 유입되는 재료가 폭 방향으로 흐름이 이루어 지도록 하는 역할을 한다. 랜드는 재료가 흐름 방향으로 균일하게 흐르게 하여 균일한 두께의 시트가 성형되도록 한다. 다이는 매니폴드와 랜드 외에도 아일랜드를 설치하여 흐름의 안정을 주도록 하는 경우가 많다. 본 연구에서는 컴퓨터 해석을 통하여 다이에서 매니폴드의 각도와 길이, 랜드 길이 그리고 아일랜드를 설계 변수로 하여 다이 출구에서 다이 폭 방향으로 균일한 흐름이 형성되도록 하는 최적의 다이형상을 연구하였다.

• The Korean Journal of Ecology
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• 제26권3호
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• pp.91-96
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• 2003

집비둘기 Columba livia 깃털의 중금속 농도를 파악하기 위하여 서울시에 서식하는 집비둘기를 서식지 환경에 따라 공단, 상업, 공원 및 주거지역으로 나누어 각 지역에 서식하는 개체들을 채집, 중금속 농도를 측정하였다. 깃털 중 철(Fe)의 농도는 공원지역에서, 망간(Mn)은 공업지역과 공원지역에서, 구리(Cu)는 공원지역에서 다른 지역에 비해 월등히 높게 나타났으며, 각 원소별로 지역간에 유의차가 존재하였다(ANOVA, p<0.05). 또한 아연(Zn)은 도심상업지역에서, 납(Pb)은 공업지역에서, 카드뮴(Cd)은 주거지역이 다른지역에 비해 약간 높았지만 지역별로 유의적인 차이가 나타나지 않았다. 간에서의 중금속농도와 깃털에서의 중금속농도와의 상관관계는 구리(r²=0.983, p<0.01)와 카드뮴(r²=0.632, p<0.01)에서 고도의 유의차가 나타났지만, 다른 원소에서는 유의성이 나타나지 않았다.

• 대한원격탐사학회지
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• 제35권4호
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• pp.517-534
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• 2019

In abrupt fire disturbances, high quality images suitable for wildfire damage assessment can be difficult to acquire. Quantifying wildfire burn area and severity are essential measures for quick short-term disaster response and efficient long-term disaster restoration. Planetscope (PS) imagery offers 3 m spatial and daily temporal resolution, which can overcome the spatio-temporal resolution tradeoff of conventional satellites, albeit at the cost of spectral resolution. This study investigated the potential of augmenting PS imagery by integrating the spectral information from Sentinel-2 (S2) differenced Normalized Burn Ratio (dNBR) to PS differenced Normalized Difference Vegetation Index (dNDVI) using histogram matching,specifically for wildfire burn area and severity assessment of the Okgye wildfire which occurred on April 4th, 2019. Due to the difficulty in acquiring reference data, the results of the study were compared to the wildfire burn area reported by Ministry of the Interior and Safety. The burn area estimates from this study demonstrated that the histogram-matched (HM) PS dNDVI image produced more accurate burn area estimates and more descriptive burn severity intervals in contrast to conventional methods using S2. The HM PS dNDVI image returned an error of only 0.691% whereas the S2 dNDVI and dNBR images overestimated the wildfire burn area by 5.32% and 106%, respectively. These improvements using PS were largely due to the higher spatial resolution, allowing for the detection of sparsely distributed patches of land and narrow roads, which were indistinguishable using S2 dNBR. In addition, the integration of spectral information from S2 in the PS image resolved saturation effects in areas of low and high burn severity.

• The Korean Journal of Ecology
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• 제1권2호
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• pp.66-71
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• 1977

The growth of red and black pines in Muan, Seochen, Gapyeong and Kochang areas was compared by means of the growth of annual ring width and stem analysis to study the process of damages caused by pine needle gall midge. Red pine forest of Seocheon area began to suffer by pine needle gall midge from 1961 and the damage was to becoming severe from 1967. The damage became so intense tha tmany forests are withering to death from spring of 1975. Black pine forest also began to suffer from 1973. Red pine forest of Muan area was supposed to be suffered from 1973. Red pine forest of Kochang area suffered by pine needle gall midge from 1967. It seems that the damage became severe from 1973 and that black pine forest was also badly damaged from that time. Red pine forest of the control plot, Gapyeong area, began to suffer from 1967 and it also became intense from 1973. Although the areas of Seocheon, Muan, Kochang, and Gapyeong are different from each other in terms of locality and the infitration period of pine needle gall equally from 1967 due to mass development of population or other factors and the damage became more intense from 1973. Black pine forest was also badly damaged from that time. Black pine seems to be stronger in insect resistant than red pine. This can be justified by the fact that it began to suffer belatedly in each area and the degree of damage is moderate. The damage of Seocheon area is the severest following Kochang. Muan area is relatively moderate but the forest becoming decrease in growth.

• Imaging Science in Dentistry
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• 제37권3호
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• pp.133-138
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• 2007

Purpose: The purpose of this study was to evaluate the morphologic features of posterior edentulous mandible for Korean patients using cross-sectional CT images. Materials and Methods: Computed tomographic cross-sectional views taken in 2004 and 2005 at Seoul National University Dental Hospital were analyzed by an oral and maxillofacial radiologist. Four indices were measured to meet the purpose of this study: 1) the horizontal distance between the alveolar crest and mandibular canal (Type), 2) the angle of the mandibular long axis (Angle), 3) the bucco-lingual location of mandibular canal, and 4) the depth of the submandibular fossa. The averages and standard deviations of the measurements were compared according to the location (the first and second molar area) and sex of the patients. Results: Statistically significant difference was found in Type, Angle, and submandibular fossa depth between the first and second molar area (p<0.05). However, there was no significant difference between men and women in any of the measured indices. Most of the mandibular canals were located in lingual side of posterior mandible. Conclusion: More care should be taken when an implant is installed on the mandibular second molar area.

• 한국표면공학회지
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• 제38권4호
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• pp.163-166
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• 2005

Carbon nanotube-copper composite structures were fabricated using composite plating method and their field emission characteristics were investigated. Multi-walled carbon nanotubes (MWNTs) synthesized by chemical vapor deposition were used in the present study. It was revealed that turn-on field was about $3.0\;V/{\mu}m$ with the current density of $0.1\;{\mu}A/cm^2.$ We observed relatively uniform emission characteristics as well as stable emission current Carbon nanotube-copper composite plating method is efficient and it has no intrinsic limit on the deposition area. Moreover, it gives strong adhesion between emitters and an electrode. Therefore, we recommend that carbon nanotube-copper composite plating method can be applied to fabricate electron field emitters for large area FEDs and large area vacuum lighting sources.