• Title/Summary/Keyword: Seok(Xi.)

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An HPLC method for the determination of thioctic acid in raw material and tablets

  • Mai, Xuan-Lan;Ahn, GyeChan;Lee, SeokHan;Kang, Jong-Seong;Woo, Mi Hee;Na, Dong-Hee;Chun, In-Koo;Kim, Kyeong Ho
    • Analytical Science and Technology
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    • v.30 no.5
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    • pp.221-225
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    • 2017
  • Thioctic acid is a vitamin-like antioxidant which is prepared as tablets and injection. The Korean Pharmacopoeia (KP XI) contains monograph for the quality control of raw thioctic acid using ultra-violet visible spectrophotometry and its formulations using high performance liquid chromatography (HPLC). In British Pharmacopoeia 2013 (BP2013), another HPLC method is used for the assay test of thioctic acid material. For the international harmonization, we present an HPLC method for quantitation of thioctic acid in both raw material and tablets. Method validation was performed to determine linearity, precision, accuracy, system suitability, and robustness. The linearity of calibration curves in the desired concentration range was high ($r^2=0.9995$), while the RSDs for intra- and inter-day precision were 0.93 ~ 1.26 % and 1.40 ~ 1.76 %, respectively. Accuracies ranged from 98.13-100.00 %. Since the system suitability, intermediate-precision and robustness of the assay were satisfactory, this method will be a valuable addition to the Korean Pharmacopoeia (KP XI).

Principles of Coloration for Hoecha and Sucha Applied to Seok (석(舃)에 적용된 회차(繢次)와 수차(繡次)의 배색원칙)

  • Choi, Yeon-Woo
    • Journal of the Korean Society of Costume
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    • v.64 no.6
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    • pp.78-90
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    • 2014
  • This paper examines the way that the principles of coloration for Hoecha(繪次) and Sucha(繡次) were applied for shoe making in ancient China and Korea. Hoecha is the principle of drawing, and Sucha is the principle of embroidery. Hoecha and Sucha is the application principle of the five colors(五方色) from the five elements(五行: metal, wood, water, fire, and earth). Hoecha matchs a color with the opposite side color, and Sucha matchs a color with the beside color. A shoe consists of Sinul(body of shoe) and ornaments attached to it. According to the ratings of shoes, Hoecha and Sucha were differently applied for coloration of Sinul and its ornaments. In general, shoes were classified into Seok and Gu. For Seok, which was the high-ranked shoes, Hoecha was applied, while Sucha was applied to Gu, the low ranked shoe. As Hoecha was originally a principle of coloration for patterns on tops(jacket. 上衣), it was applied to the high ranked shoes i.e., Seok. Also, as Sucha was a principle of coloration for patterns on bottoms(skirt. 下裳), it was applied to the low ranked shoes i.e., Gu. Thus, black was decorated on red Seok, blue on white Seok, red on black Seok, yellow on hyeon(玄: a kind of black color) Seok, and white on blue Seok, all of which were applications of the principle of Hoecha. As the application of the principle of Hoecha to Seok was also done for red Seok for males and females in late Joseon, and red Seok for the crown prince in the period of the Korean Empire, black decorations were used for red Sinul. However, for blue Seok, worn by females in the period of the Korean Empire where Ming's systems prevailed, black decorations were used, which was an application of Sucha. Though there had been no discrimination between genders in the application of Hoecha and Sucha originally, the low ranked principle of coloration was applied to Seok for females.

China's Assertive Diplomacy and East Asian Security (중국의 공세적 대외행태와 동아시아 안보)

  • Han, Seok-Hee
    • Strategy21
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    • s.33
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    • pp.37-64
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    • 2014
  • The year 2010 has been regarded as a year of China's assertive diplomacy. A series of China's behavior--including China's critical reaction to the U.S. for its sales of weapons to Taiwan, the Dalai Lama's visit to President Obama, China's arbitrary designation of 'core interests' over the South China Sea, China's inordinate reactions to the sinking of the Cheonan and Yeonpyeong bombardment, and China's activities in the Senkaku/Diaoyu island areas--has served as the witnesses to China's assertive diplomacy in 2010. The major causes of China's assertive diplomacy can be summed up by three factors: potential power transition from U.S. to China; emerging China's nationalism; and the recession of the Tao Guang Yang Hui as a diplomatic principle. But a majority of Western sinologists claim that China's assertive diplomacy is defensive in terms of its character. China's neighboring states, however, perceive its assertive diplomacy as diplomatic threat. Due to these states' geographical proximity and capability gaps with China, these neighbors experience difficulties in coping with China's behavior. In particular, China's coercive economic diplomacy, in which China tends to manipulate the neighbors' economic dependency on China for its diplomatic leverage, is a case in point for China's assertive diplomacy. China's assertiveness seems to be continued even after the inauguration of Xi Jinping government. Although the Xi government's diplomatic rhetorics in "New Type of Great Power Relationship" and the "Convention for Neighboring States Policy" sound friendly and cooperative, its subsequent behavior, like unilateral announcement of Chinese Air Defense Identification Zone (CADIZ), does not conform with its rhetoric. Overall, China's assertiveness has been consolidated as a fashion of its diplomacy, and it is likely to continue in its relations with neighbors. As a neighboring state, the ROK should approach to it with more balanced attitude. In addition, it needs to find out a new diplomatic leverage to deal with China in accordance with its security environment, in which China plays a growing role.

Application of Risk-Informed Methods to In-Service Piping Inspection in Framatome Type Nuclear Power Plants (프라마톰형 원전의 배관 가동중검사에 리스크 정보를 활용한 기법 적용)

  • Kim, Jin-Hoi;Lee, Jeong-Seok;Yun, Eun-Sub
    • Journal of the Korean Society for Nondestructive Testing
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    • v.34 no.4
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    • pp.311-317
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    • 2014
  • The Pressurized water reactor owners group (PWROG) developed and applied a risk-informed in-service inspection (RI-ISI) program, as an alternative to the existing ASME Section XI' sampling inspection method. The RI-ISI programs enhance overall safety by focusing inspections of piping at high safety significance (HSS) locations where failure mechanisms are likely to be present. Additionally, the RI-ISI program can reduce nondestructive evaluation (NDE) exams, man-rem exposure for inspectors, and inspection time, among other benefits. The RI-ISI method of in-service piping inspection was applied to 3 units (KSNPs: Korea standard nuclear power plants) and is being deployed to the other units. In this paper, the results of RI-ISI for a Framatome type (France CPI) nuclear power plant are presented. It was concluded that application of RI-ISI to the plant could enhance and maintain plant safety, as well as provide the benefits of greater reliability.

A Study on the Academic Background of Gwae(卦氣) Theory of Yiology in Han(漢) Dynasty (한역(漢易) 괘기설(卦氣說)의 학술적 배경에 대한 연구)

  • Eun, Seok-Min
    • Journal of Korean Medical classics
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    • v.21 no.3
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    • pp.69-81
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    • 2008
  • Gwae(卦氣) theory was one of the main theoretical foundation of yiology in the Han(漢)-dynasty. It was based on the concept that the trigram or hexagram of the book of change corresponds to the seasonal point such as 24 solar terms in one year, so there was so much influence from astronomy and divination system of that time in the development of theoretical principle of Gwae(卦氣) theory. Since Han(漢) Dynasty, the theoretical method such as Gwae(卦氣) theory that correlates the astronomy and divination system with the book of change, had become one of the main academic thoughts throughout the entire history in China, and it was also like that in medicine. Nevertheless there still exists the skeptical sights that Gwae(卦氣) theory was not a part of orthodox yiology, that had been developed by Confucian scholar and had also been recognized as the right path to the study of the book of change. Nowadays because of the new opportunity such as the excavation of the ancient silk script, this kind of controversy has moved on its another step. With regard to this problem, this article will treat the current thoughts about the Gwae(卦氣) theory and think about the substantial basis of each point of view.

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The Writing of 'HyangYakJipSungBang(鄕藥集成方)' and Medical Exchanges between Korea and China during the 15th Century (15세기 "향약집성방(鄕藥集成方)"의 편찬 과정에 드러난 한중(韓中) 의학교류)

  • Kang, Yeon-Seok
    • The Journal of Korean Medicine
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    • v.29 no.4
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    • pp.213-217
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    • 2008
  • Since at least the late 12th century, medical herbs grown naturally or cultivated in Korea have been referred to as 'HyangYak'(鄕藥, $Xi\bar{a}ngY\grave{a}o$). Herbs from other countries are referred to as 'DangYak'(唐藥, $D\bar{a}ngY\grave{a}o$). Some senior historians claim medicines made solely from HyangYak are purely Korean, since they originated and were developed fully within Korea. However, these localized medicines became abundant as the result of exchanges between Korea and other countries. Originally published in 1433, 'HyangYakJipSungBang' is the authoritative result of earlier writings of medical books using HyangYak. Comprised of a total of 85 volumes, it was large in scale and divided into three main sections: 1) a detailed description of the 703 kinds of HyangYak, 2) explanations of the 10,706 different herbal formulae and 959 types of symptoms or diseases, and 3) descriptions of the 1,416 various acupuncture and moxibustion formulae. It's noted that 'HyangYakJipSungBang' was not written all at once. In the process of its writing, the number of formulae increased through medical exchanges between Korea and China during the 15th century.

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NF-${\kappa}B$ Inhibitory Activities of Phenolic and Lignan Components from the Stems of Acanthopanax divaricatus var. albeofructus

  • Sun, Ya Nan;Li, Wei;Song, Seok Bean;Yan, Xi Tao;Yang, Seo Young;Kim, Young Ho
    • Natural Product Sciences
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    • v.20 no.4
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    • pp.232-236
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    • 2014
  • Acanthopanax divaricatus var. albeofructus (ADA) is commonly ingested as a traditional medicine or as a component of a health drink in Korea. In this phytochemical study, nine phenolics (1 - 9) and three lignans (10 - 12) were isolated from the MeOH extract of the stems of ADA. Chemical structures were elucidated by comparing spectroscopic data with reported values. Nuclear factor kappa B ($NF-{\kappa}B$) inhibitory activity of the isolated compounds was evaluated using an $NF-{\kappa}B$ luciferase assay in HepG2 cells. Among them, compounds 1, 3 - 8, and 11 showed significant inhibitory effects on $TNF{\alpha}$-induced $NF-{\kappa}B$ transcriptional activity in a dosedependent manner, with $IC_{50}$ values ranging from 13.25 to $37.36{\mu}M$. Further studies on potential anti-inflammatory effects and the benefits of phenolic and lignan components from ADA are warranted.

Study on the Dielectric Characteristics of Gaseous Nitrogen for Designing a High Voltage Superconducting Fault Current Limiter

  • Heo, Jeong-Il;Hong, Jong-Gi;Nam, Seok-Ho;Kang, Hyoung-Ku
    • Progress in Superconductivity and Cryogenics
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    • v.14 no.2
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    • pp.28-31
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    • 2012
  • The study on the dielectric characteristics of gaseous insulation medium is important for designing current leads of superconducting machines using a sub-cooled liquid nitrogen ($LN_2$) cooling method. In a sub-cooled $LN_2$ cooling system, the temperature of gaseous insulation medium surrounding current leads varies from the temperature of coolant to 300 K according to the displacement between the electrode system and the surface of sub-cooled $LN_2$. In this paper, AC withstand voltage experiments on gaseous nitrogen according to temperature are conducted. Also, AC withstand voltage experiments on gaseous nitrogen according to pressure, size of electrode, and gap length between two electrodes are performed. It is found that there is a functional relation between the electrical breakdown voltage and the field utilization factor (${\xi}$). As a result, the empirical formula for estimating an electrical breakdown voltage is deduced by adopting the concept of field utilization factors. It is expected that the experimental results presented in this paper are helpful to design current leads for a high voltage superconducting apparatus such as a superconducting fault current limiter (SFCL) using a sub-cooled $LN_2$ cooling system.

A Study on Mingmen(命門) theory in the light of Zhijue(知覺) (명문학설(命門學說)에 대한 지각론(知覺論)적 해석)

  • Eun, Seok-Min
    • Journal of Korean Medical classics
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    • v.24 no.6
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    • pp.49-61
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    • 2011
  • The concept of Mingmen(命門) was originated from "Neijing(內經)" and "Nanjing(難經)", respectively meaning eye in "Neijing" and right kidney in "Nanjing". But the Mingmen theory had been developed on the basis of the concept of Mingmen in "Nanjing" thereafter, and it had been influenced by the Taoist alchemy in the process of explaining the relation between the concept of Xianghuo(相火) and Yuanqi(元氣). Out of this the Mingmen theory had been changed as a thing that comprises newly the concept of Huo(火), and consequentially the dispute about the arrangement between Mingmen and Xin(心) had been consistently progressed, because Xin is the center of Huo. And on the other hand, because Xin is also the center of mind, the influence of the state of Xin which is projected to Mingmen had also been discussed. Based on the facts like this, this study will discuss the possibility of the extension of the concept about the function of Mingmen. That is, this study will add up the concept of Mingmen in "Neijing" to the Mingmen theory so far, will add up the concept of Zhijue(知覺) to the Mingmen theory. The concept of Zhijue had been originated from the Neo-Confucianism in Song dynasty, and this study thinks, in the light of the concept of Zhijue, the concept of Mingmen could be viewed from a new perspective, that is, from a view of mind.

Development of ISI UT Auto Flaw Evaluation and Acceptance Module of Nuclear Power Plants (원전 ISI UT 자동 결함평가 및 판정 모듈 개발)

  • Park, Ik-Keun;Park, Un-Su;Kim, Hyun-Mook;Kim, Chung-Seok;Um, Byong-Guk;Lee, Jong-Po
    • Proceedings of the KSME Conference
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    • 2000.11a
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    • pp.212-218
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    • 2000
  • The importance and role of pre-/in-service inspection(PSI/ISI) for nuclear power plant(NPP) components are intimately related to plant design, safety, reliability, operation, etc. In this paper, for an effective and efficient management of large amounts of PSI/ISI data in NPPs, an intelligent database program(WS-IDPIN) for PSI/ISI data management of NPP was developed. WS-IDPIN program enables the prompt extraction of previously conducted PSI/ISI conditions and results so that the time-consuming data management, painstaking data processing and analysis in the past are avoided. Furthermore, development of ISI UT auto flaw evaluation and acceptance module based on ASME Code Sec. XI were presented. This module can be used for any angle beam examination from flat plate to spherical shapes as selected by the proper azimuthal angle. This program can be further developed as a unique PSI/ISI data management expert system.

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