• The Journal of Korean Physical Therapy
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• v.22 no.3
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• pp.71-77
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• 2010

Purpose: To determine whether upregulation of inducible nitric oxide synthase (iNOS) transcription and translation is related to radicular pain in a model of lumbar disc herniation. Also, to investigate the temporal changes of mRNA expression of iNOS and the identity of iNOS and transient receptor potential vanilloid (TRPV) 1 channel expression cells in dorsal root ganglion (DRG) of a model of lumbar disc herniation. Methods: A lumbar disc herniated rat model was developed by implantation of the autologous nucleus pulposus, harvested from the coccygeal vertebra of each tail, on the left L5 nerve root just proximal to the DRG. Rats were tested for mechanical allodynia of the plantar surface of both hind paws 2 days before surgery and 1, 5, 10, 20 and 30 days postoperatively. Reverse transcription polymerase chain reaction (RT-PCR) was used to follow iNOS mRNA expression. To stain iNOS and TRPV1 in DRG, an immunohistochemical study was done 10 days after surgery. Results: A significant drop in mechanical withdrawal threshold on the ipsilateral and contralateral hind paws was observed 1 day after surgery and was prolonged to 30 days in rats with lumbar disc herniation. The expression of mRNA for iNOS peaked at postoperative day 10 on both sides of the DRG. iNOS-positive sensory neurons in the DRG varied in size from large to small diameter cells. A majority of small and intermediate sensory neurons were TRPV1-positive cells. Double immunofluorescence staining for TRPV1 and iNOS revealed that most intermediate TRPV1-positive sensory neurons co-localized with iNOS-positive neurons. Conclusion: Nucleus pulposus-induced mechanical allodynia can be generated without mechanical compression. This pain is related to temporal changes in expression of iNOS mRNA in the DRG. Co-localization of TRPV1 and iNOS in intermediate neurons of the DRG is correlated with pain modality and intensity.

• Journal of East-West Nursing Research
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• v.2 no.1
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• pp.22-36
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• 1997

Functional recovery of cerebrovascular accident (CVA) patients were studied by examining functional independence measure (FIM) to evaluate the functional state of the patients at admission to and at discharge from the hospital and its relationship with the family support. Study subjects consisted of 129 CVA patients, who were admitted and received rehabilitation treatment at K Medical Center of Oriental Medicine from August 3 to December 18, 1997. The results were as follows: 1) Total FIM score was $72.37{\pm}25.16$ at admission and $101.67{\pm}22.13$ at discharge. The difference of average score was 29.30, which was statistically significant by paired t-test. 2) The largest difference between FIM scores at admission and at clischarge was observed in items of walking and wheel-chair riding, and the smallest clifference in items of social interaction. 3) The recovery was faster with motor function than with cognitive function, because the difference of FIM scores at admission and at discharge was much larger with motor function. 4) Recovery was better in groups under age 49 than in groups above age 70. Functional recorvery was prominent especially in groups with normal sensory state and speech functions, and groups without urinary incontinence. Recovery was less significantly in patients with paraplegic patients hospitalized longer than 2 months, patients with family all the time, and patients with CVA over 11 days. 5) We could not find any relationship between functional recovery and family support. FIM scores were lower in groups of old age(r=-0.325), long stayed in hospital (r=-0.426), and long period of time after the onset of disease(r= -0.339) with a reciprocal correlation between FIM scores and these parameters. 6) Stepwise multiple regression analysis was done to evaluate factors to affect the recovery from CVA. FIM score at admission could explain 51.2 % of the functional recovery. Important factors were periods of hospitalization, state of sensory function, age, and education (listed in decreasing order of importance). In total, they could explain 64.89% of the functional recovery. These results indicate that functional recovery of CVA patients, who were admitted to oriental medicine hospital for rehabilitation treatment, could be estimated by measuring FIM scores. Recovery was significantly better at discharge from the hospital than at admission and motor function recovery rate was much faster than that of cognitive function. 2. Recommendation Based on these results, we recommend following further studies. 1) Comparative study of recovery of motor function and of sensory function would be necessary by measuring FIM scores once a week to evaluate the recovery of CVA patients. 2) It would be interesting to see whether there is any difference of functional recovery between patients treated with either western medicine or oriental medicine. 3) Psychological factors affecting the recovery of CVA patients need to be studied.

• The Journal of Korean Academy of Sensory Integration
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• v.1 no.1
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• pp.17-23
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• 2003

Objective : The purpose of this study is to identify the developmental characteristics of sensory integration according to age and sex distinction using COMPS for school-aged children and to provide the preparatory data for standardization appropriate for our social and cultural environment. Methods : The COMPS was administered to 40 normal children in the first grade of elementary school by 4 occupational therapists. Results : By comparison between age groups, 6 and 7 year olds performed similarly and statistically in all items. Between males and females, there was no significant difference in performance of all items Conclusion : Findings from the study suggested that the performance of the COMPS by children followed developmental trends. The COMPS is easy to administer to groups and beneficial to discriminate children with motor problems, and it should be standardized.

• Journal of Korean Physical Therapy Science
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• v.8 no.1
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• pp.799-811
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• 2001

The purpose of this study was to examine the effects of sensory integration therapy (SIT) on gross motor development and respiratory function of cerebral palsy children. The design of this study was one-group pre-and post-test design. Subjects of the study were arbitrarily chosen based on predetermined selection criteria among the cerebral palsy children who were treated as out-patients at one rehabilitation hospital in Kyunggi-do. The study was conducted between early April and late July in 2000. Twelve children were in the experimental group. A five-step SIT program was devised from a combination of SIT programs suggested by Ayres(1985) and Fink(1989), and an author-designed SIT program for cerebral palsy children. The experimental group was subjected to 20 to 30 minutes of SIT per session, two sessions a week for ten-week period. Collected data were statistically analyzed by SPSS PC for Wilcoxon signed rank test, and paired t-test. The results were as follows: 1. In gross motor development, post-experimental gross motor scores were higher compared to pre-experimental scores with statistical significance. 2. In respiratory function, post-experimental forced capacity vital scores were higher compared to pre-experimental scores with statistical significance. In conclusion, SIT was found to be effective in gross motor development and respiratory function. But, for the more effectiveness of SIT on gross motor development and respiratory function, further studies employing longer-time experiments are recommended.

• Archives of Plastic Surgery
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• v.47 no.6
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• pp.559-566
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• 2020

Background Infraorbital nerve dysfunction is commonly reported after zygomaticomaxillary complex fractures. We evaluated sensory changes in four designated areas (eyelid, nose, zygoma, and lip) innervated by the infraorbital nerve. This evaluation was conducted using the static two-point discrimination test and the vibration threshold test. We assessed the diagnostic significance of the blink reflex in patients with infraorbital nerve dysfunction. Methods This study included 18 patients, all of whom complained of some degree of infraorbital nerve dysfunction preoperatively. A visual analog scale, the infraorbital blink reflex, static two-point discrimination, and the vibration threshold were assessed preoperatively, at 1 month postoperatively (T1), and at a final follow-up that took place at least 4 months postoperatively (T4). The results were analyzed using a multilevel generalized linear mixed model. Results Scores on the visual analog scale significantly improved at T1 and T4. The infraorbital blink reflex significantly improved at T4. Visual analog scale scores improved more rapidly than the infraorbital blink reflex. Two-point discrimination significantly improved in all areas at T4, and the vibration perception threshold significantly improved in the eyelid at T4. Conclusions Recovery of the infraorbital blink reflex reflected the recovery of infraorbital nerve dysfunction. We also determined that the lip tended to recover later than the other areas innervated by the infraorbital nerve.

• Journal of Preventive Medicine and Public Health
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• v.46 no.sup1
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• pp.50-54
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• 2013

Out-of-home mobility is necessary for accessing commodities, making use of neighborhood facilities, and participation in meaningful social, cultural, and physical activities. Mobility also promotes healthy aging as it relates to the basic human need of physical movement. Mobility is typically assessed either with standardized performance-based tests or with self-reports of perceived difficulty in carrying out specific mobility tasks. Mobility declines with increasing age, and the most complex and demanding tasks are affected first. Sometimes people cope with declining functional capacity by making changes in their way or frequency of doing these tasks, thus avoiding facing manifest difficulties. From the physiological point of view, walking is an integrated result of the functioning of the musculoskeletal, cardio-respiratory, sensory and neural systems. Studies have shown that interventions aiming to increase muscle strength will also improve mobility. Physical activity counseling, an educational intervention aiming to increase physical activity, may also prevent mobility decline among older people. Sensory deficits, such as poor vision and hearing may increase the risk of mobility decline. Consequently, rehabilitation of sensory functions may prevent falls and decline in mobility. To promote mobility, it is not enough to target only individuals because environmental barriers to mobility may also accelerate mobility decline among older people. Communities need to promote the accessibility of physical environments while also trying to minimize negative or stereotypic attitudes toward the physical activity of older people.

• PNF and Movement
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• v.17 no.1
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• pp.19-29
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• 2019

Purpose: This study was an investigation of the effects of the bridge exercise with the sensory feedback of combined abdominal drawing-in on transverse abdominal and balance in patients with stroke. Methods: Forty subjects were randomly assigned into two groups. Subjects in the bridge exercise group (BG, n = 20) or feedback drawing-in bridge exercise group (FDBG, n = 20) were studied for 30 minutes each, twice daily, for four weeks. Outcomes were measured using affected weight distribution (AWD), anterior limit of stability (ALOS), posterior limit of stability (PLOS), timed up-and-go test (TUG), the Berg balance scale (BBS), and transverse abdominis thickness (TRA) before and after the four-week intervention period. Results: There were significant effects in the FDBG pre-intervention and post-intervention in AWD, ALOS, PLOS, TUG, BBS, and TRA. Conclusion: The results of this study suggest that the bridge exercise with sensory feedback combined with abdominal drawing-in could be beneficial for patients with stroke in terms of transverse abdominal and balance.

• The Korean Journal of Rehabilitation Nursing
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• v.11 no.2
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• pp.67-73
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• 2008

Purpose: The purpose of this study was to review and identify the meaning and components of the concept, Frailty. Method: We conducted literature review of studies that concluded the word of 'frail' or 'frailty between 1980 and 2008, and used MEDLINE, CINAHL database to select the articles. Results: Frailty is defined as a concept with multidomains, which are physical, cognitive, psychological, social. Critical characteristics of Frailty include multidominal deficiency, combined accumulation, diminished ability to keep up the independence of daily living, states beyond one's reserve capacity, dynamic relativity, proximity to adverse health outcome, aggregated symptoms. Frailty is caused by decreased physical activity, loss of sensory function, Chronic symptoms or signs, relationship with Caregiver, social isolation. Moreover, Frail elderly is at risk of falls and institutionalization. Conclusion: Frailty is very useful concept, because it has the potential to identify the elderly population at risk of adverse health outcomes. Based on this results, the appropriate tool for screening Korean Frail elderly and Nursing intervention for them needs to be developed.

• The Journal of Korean Physical Therapy
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• v.14 no.4
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• pp.20-27
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• 2002

A role for ATP in nociception and pain induction was proposed. ATP-gated P2X ion channel receptors are localized throughout the nervous system and have been identified on neurons which participate in conduction of nociceptive information from the periphery to central nervous system. We consider the role of ATP as a peripheral activator of nociceptive sensory neuron via ATP-gated ion channels.

• Journal of Haehwa Medicine
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• v.17 no.1
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• pp.129-136
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• 2008

This study was performed to investigate the cause, symptom, treatment of carpal tunnel syndrome through Western medicine and Dong-Eui-Bo-Kham(東醫寶鑑). Results & conclusions 1. Carpal tunnel syndrome is a common peripheral nerve entrapment syndrome that is characterixed by pain, numbness, sensory disturbance along the dsitribution of the meridian nerve in hand 2. Treatment of carpal tunnel syndrome have included wrist immobilization, anti-inflammatory drug, local injection of steroid, nerve block and surgical decompression. 3. Carpal tunnel syndrome seems to be similar with numbness(痺證). The causes were usually pathogenic Wind, Cold, Dampness. 4．Acupuncture, herbal medicine, herbal acupuncture were used for treatment of carpal tunnel syndrome. We considered that more study to find various and effective methods oriental medicine for carpal tunnel syndrome should be made.