• Journal of Veterinary Science
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• 제23권3호
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• pp.43.1-43.14
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• 2022

Background: Cataracts are the leading cause of impaired vision or blindness in dogs. There are many antioxidants that can prevent cataract progression, but whether they are clinically effective in dogs has not been established. Objectives: To analyze the delaying or preventing effect of oral antioxidants on canine senile cataracts through retrospective analysis. Methods: Medical records of dogs from January 1, 2015 to July 10, 2020 were reviewed. Dogs that were 8 yr of age or older with senile cataracts were included in this study. The dogs were divided into two treatment groups (dogs administered with Ocu-GLO supplement and dogs administered with Meni-One Eye R/C supplement) and a control group (dogs that were not administered any supplement). Dogs with incipient and immature cataracts were included in this study. Altogether, 112 dogs (156 eyes) with incipient cataracts and 60 dogs (77 eyes) with immature cataracts were included. The period of time that cataracts progressed from incipient to immature, and from immature to mature was recorded for each dog. Results: There was no significant delaying effect on the progression of incipient cataracts. However, both Ocu-GLO (hazard ratio = 0.265, p = 0.026) and Meni-One (hazard ratio = 0.246, p = 0.005) significantly delayed the progression of immature cataracts compared to the control group. Conclusions: Although there was no significant delaying effect of oral antioxidants on incipient cataract progression, antioxidants could be used to delay the progression of senile immature cataract.

• Journal of Acupuncture Research
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• 제23권3호
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• pp.117-127
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• 2006

Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disease associated with aging in the human population. This disease is characterized by the following 4 structural changes : Atrophy of the Cortex, Parasympathetic, and other neural cells, the existence of Neurofibrillary tangles (NFTs), and the accumulation of Senile plaques. NFTs and Senile plaques is known to be the index of this disease. Senile plaques disturbs the neutro transmission and depletes of Acetylcholine. So, Recovery of Acetylcholine is the primal objective for treating Alzheimer's disease. So, Inhibiting the activity of Acetylcholine Esterase (AChE), which causes the hydrolysus of acetylcholine into choline and acetate, can be seen as a key role for treating Alzheimer's disease. Increasing body of evidence has been demonstrated that Bee Venom Acupuncture (BV) could compete with complex protein involving in multiple step of $NF-_{\kappa}B$ activation and exert the anti-inflammatory potential of combined inhibition of the prostanoid and nitric oxide synthesis systems by inhibition of IKK and $NF-_{\kappa}B$. BV dose-dependently attenuated Scopolamine-induced Acetylcholine esterase activities in cerebral cortex and hippocampus of the mice brain. This study therefore suggests that BV acupuncture method may be useful for prevention of development or progression of AD.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1988년도 한국자동제어학술회의논문집(국제학술편); 한국전력공사연수원, 서울; 21-22 Oct. 1988
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• pp.885-890
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• 1988

This is a successive study of the development and application of an electronic safeguard system for elderly men (senile dementia patients) who wander without purpose because of declined mental capability, while retaining their physical ability. The new safeguard system is designed with some additional functions on the basis of the previously developed system. Firstly, alarms are designed not to disturb other patients at night, so that informations about doors from which the patients go out may be transmitted to helpers individually by radio paging system. Secondly, the system hardware can be set up anywhere without laying particular signal transmission cables, provided that there exist AC power distribution lines for the utilization as a transmission line of signals to alarm indicators. Thirdly, it is possible to have a grasp of the whole states of the safeguard systems at the center of operation by monitoring the operational state of each system with a necessary data acquisition according to its instruction through telecommunication network. Thus, each safeguard system can be economically supplied to the special nursing homes and the helpers are ensured more released from physical and psychological burdens so that they can devote themselves to the care of senile elderly men, thereby improving their patients' comfort and human dignity.

• 대한간호학회지
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• 제29권4호
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• pp.766-779
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• 1999

The purpose of this study was to investigate the relationship between the burden on families who live with an elderly person suffering from senile dementia, and the degree of their depression. There were 400 participants in this study, staying in the Seoul and Kyonggi areas from August 1, 1997 to February 28, 1998. Among the group, 100 participants took care of their patient at home, and another 300 participants left 100 patient at a day-care center, 100 sanatorium for senile dementia(asylum for helpless elderly people), 100 an infirmary for elderly people. Eventually 242 subjects out of the 400 were selected for the data analysis. The Zarit (1980) tool was employed to measure the degree of burden and Zung's(1965) “Self-Rating Depression Scale” was employed for the data analysis. The data was analyzed, and the percentage, t-test, ANOVA and Person's Correlation Coefficient were calculated. The results are as follows : 1. The average degree of burden that care-giving families felt was 49.13, which is somewhat high. 2. The average degree of depression that care -giving families felt was 51.95, which is relatively high. 3. The degree of burden was directly affected by the relation with the patient(F＝2.48, P＜.05), and the socio-economic status of the family(F＝5.17, P＜.05). Its also affected by the patient's educational status(F＝2.17, P＜.05). 4. The degree of depression of the family was significantly dependent on sex(t＝-2.05, P＜.05), age (F＝2.99, P＜.05), the relationship with the patient(F＝3.65, P＜.01), socio-economic status (F＝7.74, P＜.001), occupation(t＝2.82, P＜.01), health status(F＝4.42, P＜.01), and the place of residence(F＝4.30, P＜.01), The patient characteristics was significantly dependent on his/her educational status(F＝3.85, P＜.01), the period of suffering from senile dementia(F＝2.47, P＜.05), and smoking habit(F＝6.17, P＜.001). 5. The relationship between the degree of burden and that of depression reads r＝0.43, which is statistically positive correlation in the high significant level. Upon analyzing the entire summation, most care-givers for elderly patients suffering from senile dementia lack time in caring for themselves. They also experience chronic fatigue and mental discomfort caused by the isolation from society, curtailment of certain activities, a sense of responsibility for their patients, and limits of their endurance in taking care of their patients over time. In conclusion, this study emphasizes the necessity for the following propositions : 1. In order to measure the degree of burden that Korean care-giving families undergo, a new tool must be developed on the basis of Korean culture. 2. An educational program based on the demands that care-giving families undergo must be developed, and its clinical effect also has to be examined.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1996년도 제48차 추계 학술대회 연제집
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• pp.251-252
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• 1996

• Animal Systematics, Evolution and Diversity
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• 제17권1호
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• pp.91-113
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• 2001

한국산 산호충류의 분류학적 연구의 일환으로 1968년부터 2000년까지 삼면해역과 인근 도서지방에서 채집되어진 해변말미잘류 중 중근아족과 창사아족을 동정 및 분류하였다. 그 결과 8과 10속 11종이 밝혀졌으며, 이 중 유사말미잘(Isanthus capensis), 빛말미잘 (Actinostola carlgreni), 풍선말미잘 (Stomphia cuccinea), 호리병말미잘 (Parasicyonis actinostoloides) 및 섬유세닐말미잘 (Metridium senile)의 5종은 한국미기록종으로 밝혀졌다.

• The Journal of Korean Physical Therapy
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• 제15권2호
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• pp.111-122
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• 2003

The purpose of this study was to investigate the influence on sympathetic nerve system of interferential current therapy(ICT). The subjects were consisted of 20 senile patients, 10 males and 10 females with an average age of 71 years old. And systolic and diastolic blood pressure, temperature, heart rate, and respiratory were tested. The results were as follows: 1) Systolic and diastolic blood pressure were observed a statistical significance between before and during stimulation(p < .05). 2) Temperature was observed a statistical significance between before and during, and before and after 10 minutes stimulation(p < .05). 3) Heart rate and respiratory were not statistical significance(p > .05). These results are imply that electrical stimulation is directly or indirectly influence on sympathetic nerve system.

• 보험의학회지
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• 제20권
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• pp.70-77
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• 2001

Some characteristics of depression in the aged were elucidated. Compared with the previous thoughts, much more attention was given to the biological aspects of depression. However, we have to face up to and solve a variety of enigmas about depression in the aged people. They are:locations and underlying mechanisms in the cerebrum responsible for depression;relationship of senile depression to the presenile one;possible difference(s) between depression with and without psychotic features;possible neurotransmitter differences between senile and presenile depressions. New insights into these areas could bring some lights in the under standing and treatment of depresseion in the aged.

• 한국주거학회논문집
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• 제15권1호
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• pp.141-152
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• 2004

Most elderly victims of senile dementia in Korea are cared for at home. This creates hardship for their families. Recent research suggests that the physical environment can affect the treatment of dementia. In light of these findings, a prudent approach to the design of the housing environment of family with dementia sufferers is advisable. This study aims to determine the design factors that need to be considered for the housing environment of dementia, particularly for those suffering from Alzheimer's or Cerebrovascular dementia. For this study, and in-depth qualitative investigation method was employed. Principal caregivers were interviewed using various investigative tools, including objective measures, structured and non-structured questionnaires. The investigation results suggest that the need for housing environment improvement varies with the severity and type of dementia. The housing needs in this study, is expected to promote a focus on improved design management for the environment and housing of dementia and their families. The results also suggest the establishment of a welfare policy for senile dementia victims and their families.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제6권11호
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• pp.97-106
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• 2000

The purpose of this study is to suggest the architectural planning data on the senile dementia facilities. The elderly with senile dementia can be medically classified into many types. And their activity pattern is so different from each other. And so, the space for them is differently designed according to their activity. The method of space design for the elderly with alzheimer type and the elderly with cerebro vascular type is suggested in this thesis.