• Natural Product Sciences
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• v.17 no.4
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• pp.367-371
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• 2011

Effects of the extract and fractions from Parasenecio pseudotaimingasa on rat lens aldose reductase (AR) inhibition have been investigated. Among them, the n-BuOH fraction was exhibited good inhibitory potencies ($IC_{50}$ value 1.42 ${\mu}g/ml$). Phytochemical constituents were isolated from the n-BuOH fraction by open column chromatography. Their structures were elucidated as luteolin-7-O-rutinoside (1) and luteolin-7-Oglucoside (2) on the basis of spectroscopic analysis. Compounds 1 and 2 exhibited strong AR inhibitory activity, with $IC_{50}$ values of 2.37 and 1.05 ${\mu}M$, respectively. This is the first report on the isolation of compounds 1 and 2 from P. pseudotaimingasa. These results suggest that P. pseudotaimingasa could be a useful material in the development of a novel AR inhibitory agent against diabetic complications.

• Korean Journal of Plant Taxonomy
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• v.53 no.3
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• pp.201-212
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• 2023

Parasenecio pentaphylla, a new species of the genus Parasenecio from Mt. Ilwol-san, Ilwol-myeon, Yeongyang-gun, Gyeongsangbuk-do, Korea, is described and illustrated here. In Korea, this species has been recognized as P. adenostyloides, known to be a Japanese endemic species. However, it is clearly distinguished from P. adenostyloides by its involucre shape, the number of phyllaries, the number of florets per capitulum, and the ratio of the tube length to the throat length. A molecular phylogenetic analysis using the Internal Transcribed Spacer region also clearly indicated that P. pentaphyllaria was genetically distinct from P. adenostyloides. Therefore, it is recognized as an independent species, different from P. adenostyloides. The specific epithet "pentaphyllaria" was given based on its characteristic of having five phyllaries.