• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.15 no.5
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• pp.387-395
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• 2022

PDRN (Polydeoxyribonucleotide) is a DNA-derived polymer that promotes self-renewal of damaged cells and tissues as a tissue regeneration active material. PDRN is a DNA fragment cut into small sizes by various physical or chemical methods. When administered to the body, PDRN binds and stimulates the adenosine A2A receptor on the surface of tissue cells to promote cell regeneration, accelerate wound healing, and reduce pain. Although PDRN is prepared from testis or semen of fish in most cass, PDRN extraction from various plants species was performed in the present study. Among 7 tested plant species, the highest DNA yield and purity was obtained form mugwort (Chrysanthemum coronarium, C.c), followed by broccoli (Brassica oleracea, B.o). Then, we evaluated the in vitro wound healing capacity of PDRNs prepared from these two selected plants. PDRN from C.c and B.o. significantly stimulated the wound healing process at ㎍/ml range. The present study suggests that PDRN from plant species can be an effective alternative to PDRN from marine organism.

• Polymer Science and Technology
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• v.25 no.2
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• pp.114-120
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• 2014

• Polymer Science and Technology
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• v.25 no.2
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• pp.121-127
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• 2014

• Polymer Science and Technology
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• v.25 no.2
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• pp.135-139
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• 2014

• The Korean Journal of Rehabilitation Nursing
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• v.14 no.2
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• pp.118-128
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• 2011

Purpose: The purpose of this study was to explore the experiences of bereavement for main family members who had made and followed DNR decision for their family members. Method: This qualitative study was based on a grounded theory, and used in-depth interview techniques with the bereaved 10 main family members who had been treated and died under DNR order. Results: The causal condition of the family member was 'Releasing', and the main consequent phenomenon were 'Blaming self and ruminating'. The contextual condition was 'The memory of the deceased'. The action/reaction strategy was 'Purifying'. The intervening condition was 'Supporting system', and the consequence was 'Acceptance'. The experience after bereavement of the family member on DNR decision were rational processes that purified themselves and healed the guilt feeling about the decision from reflective assessment and response about DNR decision. Based on this results, the substantive theory 'Reflective self healing' was derived. Conclusion: The main family members in following DNR decision are more likely to have unhealthy emotional condition than others in normal bereavement process. But they overcame the grief of bereavement through reflective self healing process.

• Journal of Sensor Science and Technology
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• v.32 no.4
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• pp.213-218
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• 2023

Triboelectric nanogenerators (TENGs) have emerged as a highly promising energy harvesting technology capable of harnessing mechanical energy from various environmental vibrations. Their versatility in material selection and efficient conversion of mechanical energy into electric energy make them particularly attractive. TENGs can serve as a valuable technology for self-powered sensor operation in preparation for the IoT era. Additionally, they demonstrate potential for diverse applications, including energy sources for implanted medical devices (IMDs), neural therapy, and wound healing. In this review, we summarize the potential use of this universally applicable triboelectric energy harvesting technology in the disinfection and blocking of pathogens. By integrating triboelectric energy harvesting technology into human clothing, masks, and other accessories, we propose the possibility of blocking pathogens, along with technologies for removing airborne or waterborne infectious agents. Through this, we suggest that triboelectric energy harvesting technology could be an efficient alternative to existing pathogen removal technologies in the future.

• Journal of Microbiology and Biotechnology
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• v.30 no.3
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• pp.404-416
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• 2020

Bacteria that are resistant to high temperatures and alkaline environments are essential for the biological repair of damaged concrete. Alkaliphilic and halotolerant Bacillus sp. AK13 was isolated from the rhizosphere of Miscanthus sacchariflorus. Unlike other tested Bacillus species, the AK13 strain grows at pH 13 and withstands 11% (w/v) NaCl. Growth of the AK13 strain at elevated pH without urea promoted calcium carbonate (CaCO₃) formation. Irregular vaterite-like CaCO₃ minerals that were tightly attached to cells were observed using field-emission scanning electron microscopy. Energy-dispersive X-ray spectrometry, confocal laser scanning microscopy, and X-ray diffraction analyses confirmed the presence of CaCO₃ around the cell. Isotope ration mass spectrometry analysis confirmed that the majority of CO₃^2- ions in the CaCO₃ were produced by cellular respiration rather than being derived from atmospheric carbon dioxide. The minerals produced from calcium acetate-added growth medium formed smaller crystals than those formed in calcium lactate-added medium. Strain AK13 appears to heal cracks on mortar specimens when applied as a pelletized spore powder. Alkaliphilic Bacillus sp. AK13 is a promising candidate for self-healing agents in concrete.

• Journal of Korea Game Society
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• v.7 no.1
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• pp.11-20
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• 2007

Functional Games, which have developed in Korea until now, is only for the healthy people's education. There are less functional games for neglected people, specially for the disturbed's healing. I define 'Green Contents' as contents which is helpful to both of nature and human, especially to the week, and also they are not developed only for the commercial aim. Functional Games for the disturbed's healing should be developed as' Green Contents.' If functional games for the disturbed's healing will be developed as aspects of technology and contents development, they will have more effects to people, and also people will need them more. For this study, I analyze art therapy, which is a normal treatment to give a social nature and self respect to the disturbed. Also I developed a functional game program for the disturbed's healing as based on psychoanalyst's theories and suggest it's Road-map. This study will be useful for the developer who want to develop this kinds of games afterwards, and various functional games for the disturbed's healing as Green Contents should be more developed in the near future.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.26 no.2
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• pp.62-66
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• 2016

In this study, it was investigated that characteristic of crack-self-healing of hot-pressed SiC. SiC ceramics was sintered with $Al_2O_3$ and $Y_2O_3$ sintering additive by hot press. Sintering was performed in hot-press furnace in flowing argon (Ar), holding for 3 hr under $1950^{\circ}C$ and 50 MPa. The sintered SiC was machined into 3-point bending strength specimen of $3{\times}4{\times}40mm$, and introduced pre-crack by Vickers indentation at 49.6 N. Specimens were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM), 3-point bending strength after heat treatment at $1200{\sim}1400^{\circ}C$ for 1~10 hr. The best crack-self-healing ability was achieved 770 MPa 3-point bending strength by heat treatment at $1300^{\circ}C$ for 5 hr.

• The KIPS Transactions:PartA
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• v.12A no.5 s.95
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• pp.395-404
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• 2005

There have been large concerns about survivability defined as the capability of a system to perform a mission-critical role, in a timely manner, in the presence of attacks, failures. In particular, One of the most important core technologies required for the design of the ITS(Intrusion Tolerance System) that performs continuously minimal essential services even when the computer system is partially compromised because of intrusions is the survivability one of In included the dependability analysis of a reliability and availability etc. quantitative dependability analysis of the In. In this Paper, we applied self-healing mechanism utilizing two factors of self-healing mechanism (fault model and system response), the core technology of autonomic computing to secure the protection power of the ITS and consisted of a state transition diagram of the ITS composed of a primary server and a backup server. We also defined the survivability, availability, and downtime cost of the ITS, and then performed studies on simulation experiments and two cases of vulnerability attack. Simulation results show that intrusion tolerance capability at the initial state is more important than coping capability at the attack state in terms of the dependability enhancement.