• 한국컴퓨터정보학회논문지
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• 제22권10호
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• pp.151-157
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• 2017

In the case of uploading privacy information of an information owner in the Internet, the information owner may want to deliver the privacy information itself or remove such information from the search list in order to prevent third parties from accessing the privacy information of the information owner. Such a right to be forgotten may collide with the freedom of expression of a third party. The right to be forgotten, which originates from the self-determination right on privacy information based on Article 10 and 17 of the Constitution and the freedom of expression, which is based on Article 21 thereof are all relative basic rights and are both limited by Item 2 under Article 37 of the same law, which is the general limitation provision for the basic rights. Therefore, when the right to be forgotten and the freedom of expression collides, it is not possible to give priority to one of the those unilaterally. It depends on the nature of the case at hand to find a natural balance for the harmonious solution for both parties. The criteria can be the sensitivity to the privacy of the information owner caused by the disclose of the privacy information, the public benefits such information may serve, the social common good that could be expected by the disclosure of the privacy information and the damages suffered in terms of the personal interest caused by the disclosure of the information, in a comprehensive manner.

• Molecules and Cells
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• 제40권1호
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• pp.54-65
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• 2017

Although cancer/testis antigen DDX53 confers anti-cancer drug-resistance, the effect of DDX53 on cancer stem cell-like properties and autophagy remains unknown. MDA-MB-231 ($CD133^+$) cells showed higher expression of DDX53, SOX-2, NANOG and MDR1 than MDA-MB-231 ($CD133^-$). DDX53 increased in vitro self-renewal activity of MCF-7 while decreasing expression of DDX53 by siRNA lowered in vitro self-renewal activity of MDA-MB-231. DDX53 showed an interaction with EGFR and binding to the promoter sequences of EGFR. DDX53 induced resistance to anti-cancer drugs in MCF-7 cells while decreased expression of DDX53 by siRNA increased the sensitivity of MDA-MB-231 to anti-cancer drugs. Negative regulators of DDX53, such as miR-200b and miR-217, increased the sensitivity of MDA-MB-231 to anti-cancer drugs. MDA-MB-231 showed higher expression of autophagy marker proteins such as ATG-5, $pBeclin1^{Ser15}$ and LC-3I/II compared with MCF-7. DDX53 regulated the expression of marker proteins of autophagy in MCF-7 and MDA-MB-231 cells. miR-200b and miR-217 negatively regulated the expression of autophagy marker proteins. Chromatin immunoprecipitation assays showed the direct regulation of ATG-5. The decreased expression of ATG-5 by siRNA increased the sensitivity to anti-cancer drugs in MDA-MB-231 cells. In conclusion, DDX53 promotes stem cell-like properties, autophagy, and confers resistance to anti-cancer drugs in breast cancer cells.

• 식물조직배양학회지
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• 제25권4호
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• pp.237-243
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• 1998

야생종 토마토의 자가불화합성에 관여하는 S RNase유전자의 조직특이적 발현 양상을 조사하기 위하여 $\textrm{S}_{11}$ 및 $\textrm{S}_{12}$ allele에 속하는 RNase 유전자의 Promoter영역에 대한 염기 서열을 비교 분석한 결과, 전사개시점에서 상류측으로 350-500bp사이에서 양쪽 allele의 Promoter간에 상동성을 나타내는 3부분과 direct repeat sequence를 발견하였다. Promoter영역에서 이러한 부분이 S RNase 유전자가 화주특이적으로 발현하는데 영향을 줄 것으로 예상하고, 이들 영역을 중심으로 6종류의 deletion fragment를 만들어 GUS 유전자에 연결하여, 토마토의 생식조직에 microprojectile bombardment를 수행하였다. 그 결과 토마토 자가불화합성에 관여하는 S RNase 유전자의 promoter는 TATA box를 포함한 127 bP만으로도 화주조직 특이적 발현을 조절할 수 있었다. 또한 S RNase 유전자의 promoter영역내에는 토마토 화변, 자방과 심피조직들에서 negative 혹은 positive로 유전자의 발현을 유도하는 부분이 발견되었다.

• 대한간호학회지
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• 제36권6호
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• pp.1076-1084
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• 2006

Purpose: The purpose of this study was to evaluate a cognitive behavioral anger management intervention in order to increase self-consciousness and decrease anger among Korean military men, Methods: A quasi-experimental design was used for this study. Ninety two soldiers were screened for unhealthy anger expression using a questionnaire. Among them, 26 soldiers who showed unhealthy anger expression were selected for this study. They were matched by rank and assigned to either a treatment or control group. The treatment group received the intervention three consecutive times, once a week and for 120 minutes per session. Participants were assessed before and after the intervention for anger (the State-Trait Anger Scale) and self-consciousness (Self-consciousness Scale). Data was analyzed using descriptive statistics, $x^2-test$, Mann-Whitney test, and Wilcox on signed rank test. Results: There was no statistically significant decrease in anger or increase in self-consciousness between the two groups following treatment. However, there was a significant increase in private self-consciousness in the treatment group after the intervention(p=.006). Conclusion: The cognitive behavioral anger management program improves private self-consciousness in soldiers. However, Additional research is needed to explore whether long-term intervention is more effective for anger control in the military setting. The findings from this study suggest that more attention should be given to mental health care for Korean soldiers.

• 복식문화연구
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• 제24권6호
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• pp.886-902
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• 2016

This study investigated multidimensional body image, self-esteem, clothing benefits sought, and Body Image After Breast Cancer (BIABC) within surgical subgroups among breast cancer survivors. The study applied the questionnaire survey method and the main research was conducted through an online survey. The respondents included 207 breast cancer survivors between the ages of 30 and 59, each of whom received the Multidimensional Body-Self Relations Questionnaire (MBSRQ). Self-esteem, clothing benefits sought, examination, and demographic variables were measured using a 5-point Likert scale. The main results of this study are outlined below. For clothing benefit sought, six factors were formulated-pursuit of self-expression/social approval, function/health, compensation, femininity, fashion, and camouflage-and BIABC was defined by the four factors of body stigma/vulnerability, transparency, limitation and cancer concern. While MBSRQ and self-esteem did not show a statistically significant difference between groups differentiated by the surgical methods experienced, those who underwent mastectomies scored slightly lower than members of the other groups. Moreover, the reconstruction after mastectomy group showed the highest mean on self-expression/social approval, compensation, femininity and entire clothing benefits sought, followed by the lumpectomy group and mastectomy group. The lumpectomy group was found to have more positive BIABC than the mastectomy group. In particular, the mastectomy group showed a lower body stigma/vulnerability mean than the other groups. This study is meaningful in that it improves our understanding of the body image of breast cancer survivors and provides basic knowledge for developing products and marketing strategies for breast cancer survivors as consumers.

• 복식
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• 제32권
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• pp.183-200
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• 1997

The purpose of this study was to find out the mutual relations of self-efficacy proximity of cosmetic to self and proximity of clothing to self. The researcher used the scale of Sherer Mercadante Maddux Rrentice-Dunn Jacobs and Rogers(1982) for a general and social self-efficacy. The scale of Ryckman Roddins Thorton and Cantrell(1982) for a physical self-efficacy. The researcher corrected and supplemented the tools on the basis of Sontag(1987)'s scale for proximity of clothing to self. The researcher developed proximity of cos-metic to self. The subjects of this study were 172 girl students in the university. The research was analyzed by MANOVA Scheff post hoc test and Cronback a. The Results of this study were as follows: 1. The person who had a higher self-efficacy was higher in the hoy and skin-carve in the sub-causes of proximity of cosmetic to self. There was no difference in social-confidence self-satisfaction and disguise. 2. The person who had a higher self-efficacy was high in the self-expression and the physi-cal satisfaction in the sub-causes of proximity of clothing to self. There was no difference in the joy self-consciousness the consciousness of others and the novelity. 3. The person who had a higher proximity of cosmetic to self was higher in the joy, self-ex-pression and self-consciousness of others and the novelity. There was no difference in the physical satisfaction.

• BMB Reports
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• 제48권3호
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• pp.127-128
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• 2015

Tumor metastasis involves circulating and tumor-initiating capacities of metastatic cancer cells. Hepatic TM4SF5 promotes EMT for malignant growth and migration. Hepatocellular carcinoma (HCC) biomarkers remain unexplored for metastatic potential throughout metastasis. Here, novel TM4SF5/CD44 interaction-mediated self-renewal and circulating tumor cell (CTC) capacities were mechanistically explored. TM4SF5-dependent sphere growth was correlated with $CD133^+$, $CD24^-$, ALDH activity, and a physical association between CD44 and TM4SF5. The TM4SF5/CD44 interaction activated c-Src/STAT3/ Twist1/ B mi1 signaling for spheroid formation, while disturbing the interaction, expression, or activity of any component in this signaling pathway inhibited spheroid formation. In serial xenografts of less than 5,000 cells/injection, TM4SF5-positive tumors exhibited locally-increased CD44 expression, suggesting tumor cell differentiation. TM4SF5-positive cells were identified circulating in blood 4 to 6 weeks after orthotopic liver-injection. Anti-TM4SF reagents blocked their metastasis to distal intestinal organs. Altogether, our results provide evidence that TM4SF5 promotes self-renewal and CTC properties supported by $CD133^+/TM4SF5^+/CD44^+^{(TM4SF5-bound)}/ALDH^+/CD24^-$ markers during HCC metastasis.

• 한국산업정보학회논문지
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• 제25권3호
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• pp.83-97
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• 2020

일관된 온/오프 아이덴티티 관리를 통해 양방향 커뮤니케이션을 강화하고 상호작용을 촉진하는 SNS의 본질과는 다르게 타인의 의견을 일방적으로 수용하는 수동적인 이용행태가 강화되고 있으며 표현의 자유를 즐기기 위해 페이스북을 익명 또는 가명으로 사용하는 사람들이 증가하는 경향을 보인다. 이처럼 변형적으로 나타나는 이용행태를 설명하기 위해 본 연구는 자존감, 실명사용, 의사표현과 같은 심리적·행태적 변인을 포함한 통합모형을 제시하고자 하였다. 연구결과 자존감이 실명사용과 자기노출에 영향을 주는 것으로 나타났으며, 실명사용자가 자신에 대해 더 많은 정보를 노출함에 따라 관계에 대한 만족도와 지속이용의도가 증가하는 결과를 보였다.

• 한국간호교육학회지
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• 제16권1호
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• pp.33-42
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• 2010

Purpose: The purpose of this study was to ascertain the degree of students' educational satisfaction according to their Problem-based learning strategy. Method: The subjects were 277 nursing students in C College. A questionnaire modified by researchers was used and analyzed by the SPSS WIN 12.0 program. Result: This study showed that there's a positive relationship between the level of students' educational satisfaction and their learning strategies, including collaborative, self-directed, self-expression and time management strategies. Those who were in the second year and those who have considered temporary absence from school and/or change of academic courses used the least learning strategies and showed the lowest level of educational satisfaction. The top three learning strategies influencing educational satisfaction were time management, collaborative strategies and self-directed strategies respectively. Self-expression strategy was not statistically significant as an influencing factor on educational satisfaction. Conclusion: The more learning strategies that are used, the higher the level of educational satisfaction as a whole. Further studies on how to increase student's educational satisfaction and a way to advance in learning strategies are recommended.

• 복식문화연구
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• 제7권4호
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• pp.139-154
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• 1999

The objectives of this study were to find relationships between ego identity and clothing benefits, and to examine the influence of ego identity, clothing attributes evaluation, and demographic variables on clothing benefits. The subjects were 405 college students(male : 164, female : 241) in Seoul. Six factors of clothing benefit derived by factor analysis : fashion, comfort, social recognition, self-expression, recognized brand, and economy. Males with higher goal-directedness of ego identity had less interest in the benefits of social recognition and recognized brand. The higher the uniqueness of ego identity females had, the higher the social recognition and the lower the comfort. Social recognition of males was influenced by self-acceptance(-), style, and fastener(R²=17.7%). and recognized brand influenced by parents\` education, goal-directedness(-), and allowance(R²=27.5%). Fashion of females was influenced by style, allowance(-), and goal-directedness(-)(R²=18.7%), comfort unfluenced by uniqueness(-), size, and allowance(-)(R²=14.6%), and self-expression influenced by style, allowance, fastener, and interpersonal relation(R²=28.0%). The present findings mean that allowance and ego identity such as goal-directedness, self-acceptance, interpersonal relation were meaningful variables that affect clothing benefits.