• 대한간호학회지
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• 제25권2호
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• pp.295-315
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• 1995

This qualitative nursing research used a hermeneutic phenomenological approach to discover meaning in mid - aged women's experience of mastectomy. The ultimate aim of the inquiry was to discover the essence of mid-aged women's experience and promote understanding. The study was guided by Van Manen's method for doing research. The method of inquiry included. turning to phenomenon of interest ; inquiring and investigating experience as it was lived rather than as conceptualized ; reflecting and analyzing essential themes which characterize phenomenon : and describing phenomenon through art of writing and rewriting. Multiple strategies for data collecting were needed : in depth face-to-face interview ; analysis of women's writings ; artistic works : and analysis of examples of phenomenon in art, litera lure, and drama. Although the experience was different for all of the women interviewd, essential themes of experience emerged : Self-discovering of vicious disease, Divining punishment-unfortunate women, loss of self though the scar, a night-mare, change of life values and attitudes, rediscovering living alone, living through with fearing of death. Findings from artistic and creative inquiry further validated findings and meaning descovered. The study illuminated meaning and simultaneously validated the phenomenological research process. Essential themes for understanding women's experience, implications for education, research, and practice, direction and need for continuing inquiry were identified.

• 한국콘텐츠학회논문지
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• 제13권12호
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• pp.672-679
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• 2013

창의성은 문제인식과 해결방법으로 상상력을 통한 새로운 이미지의 사고능력과 표현이다. 이 연구는 신체움직임의 창의성이론을 탐구하고 창의성 요인을 분석하였다. 연구결과, 신체움직임의 창의성은 첫째, 움직임 자각 둘째, 신체움직임 디자인 셋째, 움직임의 발견, 넷째, 움직임활용이라는 단계가 필요하다. 자기지각과 자아개념을 통한 새로운 이미지의 활용은 문제인식과 해결기능에 대한 창의적인 향상을 가져온다. 결론적으로 신체움직임의 창의성은 상호작용에 의한 '제3의 힘'과 '흐름의 유연성'으로 신체움직임의 무한성을 의미한다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제7권7호
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• pp.1585-1609
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• 2013

Over recent years, enormous amounts of research in wireless sensor networks (WSNs) have been conducted, due to its multifarious applications such as in environmental monitoring, object tracking, disaster management, manufacturing, monitoring and control. In some of WSN applications dependent the energy-efficient and link reliability are demanded. Hence, this paper presents a routing protocol that considers these two criteria. We propose a new mechanism called Reliable Routing Scheme for Energy-Balanced (RRSEB) to reduce the packets dropped during the data communications. It is based on Swarm Intelligence (SI) using the Ant Colony Optimization (ACO) method. The RRSEB is a self-adaptive method to ensure the high routing reliability in WSNs, if the failures occur due to the movement of the sensor nodes or sensor node's energy depletion. This is done by introducing a new method to create alternative paths together with the data routing obtained during the path discovery stage. The goal of this operation is to update and offer new routing information in order to construct the multiple paths resulting in an increased reliability of the sensor network. From the simulation, we have seen that the proposed method shows better results in terms of packet delivery ratio and energy efficiency.

• 가정과삶의질연구
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• 제26권5호
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• pp.109-127
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• 2008

There are few studies on the characteristics of debtors in individual rehabilitation procedures, though research in this field is needed. The scarcity of research means that public policy and perception are being made with inadequate information and, to a certain extent, based on personal prejudices and misconceptions. The purpose of this study was to find out demographic, economic and psychological characteristics of debtors in individual rehabilitation procedures. For this study, an in-depth interview was used. The major findings were as follows : The focus of this study is debtors in individual rehabilitation procedures. They were all under 40 and received relatively high educations. Interestingly, they showed a high tendency to use debt and an inability to manage their money. They had short time horizons and imperfect self-control in consumption and borrowing decisions. Monthly income, expenditures, asset and debt of the debtors, and monthly payment to creditors were reported. There were a lot of reasons for their bankruptcy : business failure, job loss, the cost of raising children, and expenditures for entertainment causing them to file for individual rehabilitation procedures. One of the major conclusions of this study was the discovery that their psychological characteristics were nearly the same. The implications of the study suggest that financial education and counseling must consider psychological characteristics.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.557-557
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• 2012

Silicatein-${\alpha}$, the enzyme extracted from silica spicules in glass sponges, has been studied extensively in the way of chemistry from 1999, in which the pioneering work by Morse, D. E. - the discovery of the enzymatic hydrolysis in Silicatein-${\alpha}$ - was published. Since its reaction conditions are physiologically favored, synthesis of various materials, such as gallium oxide, zirconium oxide, and silicon oxide, was achieved without any hazardous wastes. Although some groups synthesized oxide films and particles, they have not achieved yet controlled morphogenesis in the reaction conditions mentioned above. With the knowledge of catalytic triad involved in hydrolysis of silicone alkoxide and oligomerization of silicic acid, we designed the novel peptide amphiphiles to not only form self-assembled structure, but also display similar activities to silicatein-${\alpha}$. Designed templates were able to self-assemble into left-handed helices for the peptide amphiphiles with L-form amino acid, catalyzing polycondensation of silicic acids onto the surface of them. It led to the formation of silica helices with 30-50 nm diameters. These results were characterized by various techniques, including SEM, TEM, and STEM. Given the situation that nano-bio-technology, the bio-applicable technology in nanometer scale, has been attracting considerable attention; this result could be applied to the latest applications in biotechnology, such as biosensors, lab-on-a-chip, biocompatible nanodevices.

• 정보처리학회논문지D
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• 제10D권2호
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• pp.277-282
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• 2003

웹으로부터 유용한 정보를 얻기 위한 연구는 현재 많이 진행되고 있다. 본 논문에서는 특히 웹 로그 데이터의 희소성에 대한 문제 해결과 이를 통한 웹 사용자의 군집화 방안에 대하여 연구하였다. MCMC 방법의 베이지안 추론에 의한 결측치 대체 기법을 이용하여 웹 데이터의 희소성을 제거하였고, 주성분에 의한 산점도를 통하여 형상지도의 차원을 결정한 자기 조직화지도를 이용하여 웹 사용자의 군집화를 수행하였다. 제안 기법은 기존의 방법들에 비해 모형의 정확도와 빠른 학습 시간을 제공하여 주었다. KDD Cup 데이터를 이용한 실험을 통하여 제안 방법에 대한 문제 해결 절차 및 성능 평가를 객관적으로 확인하였다.

• 영미문화
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• 제13권1호
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• pp.1-28
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• 2013

Edward Abbey is regarded as one of the most influential ecological or nature writers. He celebrates the American Southwestern desert, argues for wilderness preservation, and advocates politically-oriented environmental activism to defend wilderness. He, however, does not classify himself as a nature writer, but rather places himself in the tradition of a kind of autography. His books show his fascination with the delicate harmony of the desert, and at the same time his personal journey over the desert. That is, eco-centered, he keeps his journey into the heart of the desert. He finds the desert harsh, brutal, fatal, and most of all, indifferent. The desert reveals simplicity and mystery, silence and revelation, and emptiness and fulfillment. This mythical and paradoxical essence of the desert draws him into the place and inspires redemptive humility and beauty, which, in turn, peel off his old ego or self. During his journey, Abbey tries to immerge himself with the desert yet remains intact and individual. The desert serves for him as the bedrock which sustains him and offers an opportunity to gain a new whole perspective. Like a pocket hunter in the desert whom he characterizes himself, he sticks to the desert to dig out ground for his existence and survival. Pulling the energy and force of the desert into his soul, Abbey is free, or compelled to contemplate what is beyond the human. His experience in and of the desert leads to a discovery of self and initiates selfhood.

• BMB Reports
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• 제54권7호
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• pp.335-343
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• 2021

Cancer stem cells (CSCs) are a subpopulation of cancer that can self-renew and differentiate into large tumor masses. Evidence accumulated to date shows that CSCs affect tumor proliferation, recurrence, and resistance to chemotherapy. Recent studies have shown that, like stem cells, CSCs maintain cells with self-renewal capacity by means of asymmetric division and promote cell proliferation by means of symmetric division. This cell division is regulated by fate determinants, such as the NUMB protein, which recently has also been confirmed as a tumor suppressor. Loss of NUMB expression leads to uncontrolled proliferation and amplification of the CSC pool, which promotes the Notch signaling pathway and reduces the expression of the p53 protein. NUMB genes are alternatively spliced to produce six functionally distinct isoforms. An interesting recent discovery is that the protein NUMB isoform produced by alternative splicing of NUMB plays an important role in promoting carcinogenesis. In this review, we summarize the known functions of NUMB and NUMB isoforms related to the proliferation and generation of CSCs.

• 유통과학연구
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• 제17권3호
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• pp.107-116
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• 2019

Purpose - Why, why is it difficult to predict the appropriateness of self-employment, and what are the countermeasures and policy proposals to overcome. This study intends to further develop the field of statistical variables. It is necessary to overcome the limitation of existing proper scale research in Korea. We need to find statistical variables that can determine the appropriateness of self-employment in Korea. These efforts will be helpful in evaluating OECD countries and statistics and developing domestic economic indicators. Research design, data, and methodology - It is the discovery of statistical indicators and complementary indicators that have not been revealed in previous studies. Therefore, we sought to find new statistical parameters based on the statistics of the Korea National Statistical Office, the Bank of Korea, and overseas OECD statistics. (Proper Size of Adequacy) is defined as the specific gravity or number of the self-employed in Korea, which is shown as "Out Put" by statistical analysis of STATA panel statistical data. It is possible to further develop variables such as gross domestic product, gross national product, economic growth rate, unemployment rate, income tax rate, consumer price, tax level, exports, import amount, bill default I want to dig. Results - In addition to expanding economic indicators that can be explained by self-employment determinants, we have developed a variety of methods such as linear and non-linear (U-shaped, inverted U-shaped). It is the improvement of the self-employment determinants and the analysis method to estimate the appropriate scale. Conclusions - The proposed contents are reflected in self - employment appropriateness evaluation data and hope to help the government to select the policy support and to evaluate the government business after the policy support. These efforts are expected to be of great help to operators operating their own businesses, and to government and related institutional practitioners who support them. In this way, self-employment will be created in accordance with the Korean situation, where the happy life of all the people becomes the premise and the inclusive economic activities are guaranteed. It will improve the method of analyzing proper scale of small business owners and self-employed in Korea.

• BMB Reports
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• 제42권2호
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• pp.65-71
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• 2009

Autophagy, which is a process of self eating, has gained interest in the past decade due to its both beneficial and controversial roles in various biological phenomena. The discovery of autophagy genes (ATG) in yeast has led to focused research designed to elucidate the mechanism and regulation of this process. The role of autophagy in a variety of biological phenomena, including human disease, is still the subject of debate. However, recent findings suggest that autophagy is a highly regulated process with both beneficial and negative effects. Indeed, studies conducted using various model organisms have demonstrated that increased autophagy leads to an extended lifespan. Despite these findings, it is still unknown if all pathways leading to extended lifespan converge at the process of autophagy or not. Here, an overview of modern developments related to the process of autophagy, its regulation and the molecular machinery involved is presented. In addition, this review focuses on one of the beneficial aspects of autophagy, its role in lifespan regulation.