• Genomics & Informatics
• /
• v.20 no.4
• /
• pp.43.1-43.18
• /
• 2022

Atropa belladonna is a valuable medicinal plant and a commercial source of tropane alkaloids, which are frequently utilized in therapeutic practice. In this study, bioinformatic methodologies were used to examine the pattern of coding sequences and the factors that might influence codon usage bias in the chloroplast genome of Atropa belladonna and other nightshade genomes. The chloroplast engineering being a promising field in modern biotechnology, the characterization of chloroplast genome is very important. The results revealed that the chloroplast genomes of Nicotiana tabacum, Solanum lycopersicum, Capsicum frutescens, Datura stramonium, Lyciumbarbarum, Solanum melongena, and Solanum tuberosum exhibited comparable codon usage patterns. In these chloroplast genomes, we observed a weak codon usage bias. According to the correspondence analysis, the genesis of the codon use bias in these chloroplast genes might be explained by natural selection, directed mutational pressure, and other factors. GC12 and GC3S were shown to have no meaningful relationship. Further research revealed that natural selection primarily shaped the codon usage in A. belladonna and other nightshade genomes for translational efficiency. The sequencing properties of these chloroplast genomes were also investigated by investing the occurrences of palindromes and inverted repeats, which would be useful for future research on medicinal plants.

• Journal of the Korean Statistical Society
• /
• v.27 no.4
• /
• pp.397-405
• /
• 1998

We develop parametric bootstrap model selection criteria in an example to fit a random sample to either a general normal distribution or a normal distribution with prespecified mean. We apply the bootstrap methods in two ways; one considers the direct substitution of estimated parameter for the unknown parameter, and the other focuses on the bias correction. These bootstrap model selection criteria are compared with AIC. We illustrate that all the selection rules reduce to the one sample t-test, where the cutoff points converge to some certain points as the sample size increases.

• Proceedings of the Korean Institute of Intelligent Systems Conference
• /
• 2004.10a
• /
• pp.313-316
• /
• 2004

Model selection is the process that sets up the regularization parameter in the support vector machine or regularization network by using the external methods such as general cross validation or L-curve criterion. This paper suggests that the regularization parameter can be obtained simultaneously within the learning process of neural networks without resort to separate selection methods. In this paper, extended kernel method is introduced. The relationship between regularization parameter and the bias term in the extended kernel is established. Experimental results show the effectiveness of the new model selection method.

• 월간산업보건
• /
• s.74
• /
• pp.26-31
• /
• 1994

• The Journal of Fisheries Business Administration
• /
• v.40 no.3
• /
• pp.147-167
• /
• 2009

The objective of this study is to analyze the determinants of at-home laver consumption expenditures using the data from a survey of households implemented in 2009. It happened that non-response ratios of monthly expenditures on dry laver and flavored laver among sampled households are 18.8% and 25.6%. Accordingly, this study tries to analyze the determinants affecting at-home laver consumption expenditures by using type II tobit model, one of sample selection models, to deal with sample selection bias caused from non-response data. Analysis results show the age variable positively affects expenditures on dry laver but negatively contributes to expenditures on flavored laver. In addition, the household size, the household's income, the degree of preference for laver have positive relationships with both expenditures. Household size elasticity and income elasticity of the expenditure on dry laver are estimated as 0.220 and 0.251. In the case of flavored laver, these elasticities are estimated as 0.484 and 0.261. Such analysis results can provide information on division of the at-home laver consumption market into groups with high willingness to expense and implementation of detailed marketing strategies to increase at-home laver consumption. The methodology of this study can be applied to consumer preference analysis on other marine products and other analyses on sample with non-response data in the fishery research.

• Journal of Korean Society of Rural Planning
• /
• v.27 no.4
• /
• pp.1-12
• /
• 2021

The purpose of this study is to analyze the effect of crop diversification on farm households' agricultural income. Abundant literature have explored the determinants and efficient strategies for crop diversification. Yet, there is a paucity of research studies that empirically test the effectiveness of crop diversification as a profitable farm management strategy. Utilizing the 2015 Agricultural Census, this study adopts a quasi-experimental research design to compare the outcomes between farm households that opted for crop diversification and farm households that did not engage in such a strategy. In doing so, this study applies the Heckman Selection Model and the decomposition technique to address the problem of selection bias and to identify the causal effect. Our empirical results show that farms that implement diversification are more likely to earn higher agricultural income than non-diversified farms, although the difference would not be much substantial. This study concludes with several policy proposals to stabilize agricultural income in conjunction with crop diversification.

• Journal of the Korean Data and Information Science Society
• /
• v.28 no.5
• /
• pp.1077-1085
• /
• 2017

In this study, we have found the major factors which affect Korean women's wage analysing the data provided by 2015 Korea Labor Panel Survey (KLIPS). In general, wage data is difficult to analyze because random sampling is infeasible. Heckman sample selection model is the most widely used method for analysing the data with sample selection. Heckman proposed two kinds of selection models: the one is the model with maximum likelihood method and the other is the Heckman two stage model. Heckman two stage model is known to be robust to the normal assumption of bivariate error terms. Recently, Marchenko and Genton (2012) proposed the Heckman selectiont model which generalizes the Heckman two stage model and concluded that Heckman selection-t model is more robust to the error assumptions. Employing the two models, we carried out the analysis of the data and we compared those results.

• Journal of Korea Water Resources Association
• /
• v.53 no.4
• /
• pp.249-258
• /
• 2020

Many climate studies have used the general circulation models (GCMs) for climate change, which can be currently available more than sixty GCMs as part of the Assessment Report (AR5). There are several types of uncertainty in climate studies using GCMs. Various studies are currently being conducted to reduce the uncertainty associated with GCMs, and the bias correction method used to reduce the difference between the simulated and the observed rainfall. Therefore, this study mainly considered climate change scenarios from nine GCMs, and then quantile mapping methods were applied to correct biases in climate change scenarios for each station during the historical period (1970-2005). Moreover, the monthly rainfall for the future period (2011-2100) is obtained from the RCP 4.5 scenario. Based on the bias-corrected rainfall, the standard deviation and the inter-quartile range (IQR) from the first to third quartiles were estimated. For 2071-2100, the uncertainty for the selection of GCMs is larger than that for the selection of bias correction methods and vice versa for 2011-2040. Therefore, this study showed that the selection of GCMs and the bias correction methods can affect the result for the future climate projection.

• Parasites, Hosts and Diseases
• /
• v.53 no.6
• /
• pp.689-697
• /
• 2015

The tapeworm Taenia solium is an important human zoonotic parasite that causes great economic loss and also endangers public health. At present, an effective vaccine that will prevent infection and chemotherapy without any side effect remains to be developed. In this study, codon usage patterns in the T. solium genome were examined through 8,484 protein-coding genes. Neutrality analysis showed that T. solium had a narrow GC distribution, and a significant correlation was observed between GC12 and GC3. Examination of an NC (ENC vs GC3s)-plot showed a few genes on or close to the expected curve, but the majority of points with low-ENC (the effective number of codons) values were detected below the expected curve, suggesting that mutational bias plays a major role in shaping codon usage. The Parity Rule 2 plot (PR2) analysis showed that GC and AT were not used proportionally. We also identified 26 optimal codons in the T. solium genome, all of which ended with either a G or C residue. These optimal codons in the T. solium genome are likely consistent with tRNAs that are highly expressed in the cell, suggesting that mutational and translational selection forces are probably driving factors of codon usage bias in the T. solium genome.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.10
• /
• pp.169-178
• /
• 2019

This study examined the influence and role of college students' career preference type on the decision-making process of career selection, and also analyzed the effect on the confession bias in the process. The data was collected from June 20th to July 9th, 2017. The case analysis method was used for three times over 20 days by interviewing university students in the metropolitan area. The results of the analysis of the data from the study participants show that there are differences in the degree of individuals regardless of the preferred occupation type and career aptitude, but mostly there is a bias toward career and career. Confirmed biased thinking is a phenomenon that is shaped by the psychological and environmental factors of the research participants and that they try to fit themselves into a framework that reflects social awareness. The implication of this study is that the preference type affects the selection of the major, and that confirmation bias is a hindrance to proper employment and a job search. The preference for the individual job type should be properly established. Environment and opportunity should be provided.