• Title/Summary/Keyword: Segmental Method

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Long-term Prognostic Factors in Pediatric Focal Segmental Glomerulosclerosis (소아 국소성 분절성 사구체 경화증에서의 장기예후인자 분석)

  • Kim Eun A;Lee Young-Mock;Kim Ji Hong;Lee Jae Seung;Kim Pyung-Kil;Jung Hyun Joo
    • Childhood Kidney Diseases
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    • v.5 no.2
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    • pp.125-135
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    • 2001
  • Purpose : Efforts to predict long-term outcome of focal segmental glomerulosclerosis(FSCS) have been made but have yielded conflicting results. Reports are rare especially in Pediatric patients. In this study, we reviewed the predictable prognostic factors in patients of FSGS Method : Fifty children who diagnosed as biopsy-proven FSGS at department of pediatrics at Yonsei university were studied retrospectively. Based on medical records, response to treatment and pathologic slides, we compared normal renal function group and decreased renal function group, assessed the factors affecting renal survival and progression to renal failure. Results : The mean age at onset was 8 1/12 years, sex ratio was 2.3 : 1, and the mean duration of follow-up was 7 1/12 years. The overall renal survival rate was $34\%$ at 5 years, $8\%$ at 10 years Five-year survival rate was $74\%$ in normal renal function group and $27\%$ in decreased renal function group. Between the two groups, there were no significant differences in age at onset, sex ratio, amount of proteinuria, incidence of hematuria and hypertension, mesangial hypercellularity. Decreased renal function group showed higher serum creatinine level, poor response to treatment, higher percent of glomeruli with sclerosis, moderate to severe tubulointerstitial change and vascular change(P<0.05). The prognostic factors of renal survival rate were same as above and incidence of hypertension also affected renal survival( P<0.05). The progression rate to renal failure did not show statistically significant factor. Conclusion : We reviewed the factors affecting long-term outcome of FSGS. Serum creatinine level, steroid responsiveness, and the degree of glomerulosclerosis were significant prognostic factors. (J Korean Soc Pediatr Nephrol 2001 ;5 : 125-35)

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The Effects of Programmed Dietary System of a Mixture of Natural Supplements on the Composition, Serum Lipids and the Leptin Levels (천연 소재 조성물의 3.3.3 System Diet Program이 각 단계별 신체조성, 혈청 지질 개선 효과 및 Leptin 수준에 미치는 영향에 관한 연구)

  • 이성희;조재민;이민숙;조병남;주상섭;조양희;김경탁;진동규;노숙령
    • Korean Journal of Community Nutrition
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    • v.8 no.3
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    • pp.356-367
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    • 2003
  • This study was to investigate the effects of a silk peptide, and prune and raspberry mixture on the body fat, serum lipid composition and fat distribution in Korean women during the time they received these supplements. During the 4 month period of this research (June to October, 2002), 75 women (average age 22.9 yr) were selected as subjects. Their nutrient intake was investigated by use of a questionnaire and the 24-hour recall method. Antropometric assessments of the subjects were investigated by using the SBIA Method (Segmental Bioimpedance Assay, Inbody 3.0). The results were as follows: their mean body weight was 59.3 kg, their mean body height was 161.7 cm and their mean Basal Metabolic Indices (BMI) was 22.7. The status of their dietary fiber intake significantly increased (p < 0.05) after use of the supplements. Their body fat significantly decreased following the $3^{rd}$ stage of supplementation (p < 0.05), and their percent of body fat signiflcantly decreased after supplementation (p < 0.05). Their triceps and suprailiac circumference significantly decreased following the $3^{rd}$ stage of supplementation (p < 0.05). Their waist circumferences and waist-hip ratios (WHR) significantly decreased after both the $2^{nd}$and $3^{rd}$ stage of supplementation (p < 0.05). Their total cholesterol significantly decreased following the $3^{rd}$ stage of supplementation, as compared to their baseline results and those obtained following the 1$^{st}$ stage of supplementation (p < 0.05). Their LDL-cholesterol and LDL / HDL ratios significantly decreased following the $3^{rd}$ stage of supplementation, as compared to their baseline results and those obtained following the 1$^{st}$ stage of supplementation (p < 0.05). Their 4-HNE and total antioxidant statuses significantly decreased following the $2^{nd}$ and $3^{rd}$stage of supplementation, as compared to their baseline results and those obtained following the $1^{st}$ stage of supplementation (p <0.05). Their $2^{nd}$ stage supplementation results were significantly negatively correlated with their triceps measurements and WHR (p < 0.05). Their $3^{rd}$stage supplementation results were significantly negatively correlated with their anterior thigh measurements (p < 0.05). The above results show that prune, raspberry, silk peptide and dietary fiber supplementation to a routine diet improves body fat distribution, total cholesterol, and triglyceride levels. The decrease of abdominal fat and WHR were especially noteworthy. This implies a decrease of risk factors. (Korean J Community Nutrition 8(3) : 356~367, 2003)003)

A Study on Site Repeat Visit and Purchase Decision-Making of On-line Consumer using Two-Stage Mixture Regression Analysis - Focus on Internet Shopping Mall - (2단계 Mixture Model을 이용한 온라인 소비 자의 방문행동특성이 사이트 재방문과 구매에 미치는 영향에 관한 연구 - 온라인 쇼핑몰을 중심으로 -)

  • Lee, Young-Seung
    • Journal of Global Scholars of Marketing Science
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    • v.13
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    • pp.135-158
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    • 2004
  • On-line consumers have some visit behavior characteristics when they visit internet-shopping mall between visit-stage and purchase-stage. Therefore, information of on-line consumers have influenced on internet-shopping mall's profitabilities at site manager's perspectives. For examples, Are any on-line consumers continuous visiting under any situations? Or are any on-line consumers purchased on any specific internet-shopping mall? Expecially in this paper, researcher tried to understand visit behavioral characteristics of on-line consumers using two-stage mixture regression analysis. Throughout this process, it could be proposed method, which could be reinforced competitiveness of internet-shopping mall by segmental decision-making method. Additionally, it is expected that visit behavioral characteristics' information could be supplied strategic implications between visit-stage and purchase-stage Throughout empirical test it could be proved two-stage decision-making process, which decision-making process of on-line consumers would be processed visit-stage and purchase-stage. In this study, researcher proposed suitable response strategy after understanding visiting behavioral characteristics of on-line consumers. This paper has some academical contributions, which visit behavioral characteristics of on-line consumers could be grasped the meaning by site stickiness and navigation pattern.

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Tone Quality Improvement Algorithm using Intelligent Estimation of Noise Pattern (잡음 패턴의 지능적 추정을 통한 음질 개선 알고리즘)

  • Seo, Joung-Kook;Cha, Hyung-Tai
    • Journal of the Korean Institute of Intelligent Systems
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    • v.15 no.2
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    • pp.230-235
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    • 2005
  • In this paper, we propose an algorithm that improves a tone quality of a noisy audio signal in order to enhance a performance of perceptual filter using intelligent estimation of noise pattern from a band degraded by additive noise. The proposed method doesn't use the estimated noise which is obtained from silent range. Instead new estimated noise according to the power of signal and effect of noise variation is considered for each frame. So the noisy audio signal is enhanced by the method which controls a estimation of noise Pattern effectively in a noise corruption band. To show the performance of the proposed algorithm, various input signals which had a different signal-to-noise ratio(SNR) such as $5\cal{dB},\;10\cal{dB},\;15\cal{dB}\;and\;20\cal{dB}$ were used to test the proposed algorithm. we carry out SSNR and NMR of objective measurement and MOS test of subjective measurement. An approximate improvement of $7.4\cal{dB},\;6.8\cal{dB},\;5.7\cal{dB},\;5.1\cal{dB}$ in SSNR and $15.7\cal{dB},\;15.5\cal{dB},\;15.2\cal{dB},\;14.8\cal{dB}$ in NMR is achieved with the input signals, respectively. And we confirm the enhancement of tone quality in terms of mean opinion score(MOS) test which is result of subjective measurement.

Analysis on Bond Characteristics of Reinforcements for UHPC Hybrid Cable-Stayed Bridge Deck Joints (초고성능 콘크리트 하이브리드 사장교 바닥판 접합부 철근의 부착 성능에 대한 해석)

  • Seonwoo, Yoon Ho;Park, Sung Kyun;Kwahk, Im Jong;Yoon, Young Soo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.3A
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    • pp.207-214
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    • 2011
  • Ultra High Performance Concrete (UHPC), which is characterized by its high strength and advanced ductile behavior that is much superior to those of convention concrete, is a useful material to make thinner and longer bridges. The precast segmental construction method utilizing UHPC has been mainly studied because cast-in-place UHPC is very difficult and complicate to be achieved. As a part of those research, the structural performance evaluation of different types of joint connection method for hybrid cable-stayed bridge utilizing UHPC by using nonlinear analyses is performed in this study. The bond stress at joint is obtained by section force analyses for a 600 m cable-stayed bridge deck, and compared with the required bond stress at joint. Analysis results show that the U Type connection and straight type connection resist the highest ultimate load and bond strength, respectively. In addition, all considered joint connection systems satisfy the bond performances at joint required in the final stage of cable-stayed bridge utilizing UHPC.

Clamp and Sew Technique without Distal Perfusion for the Management of Traumatic Descending Thoracic Aortic Rupture (외상성 흉부 하행 대동맥 파열에서 원위부 관류 없이 시행한 겸자 봉합술)

  • Seok, Yang-Ki;Lee, Jong-Tae;Kim, Gun-Jik;Park, Il;Cho, Joon-Yong
    • Journal of Chest Surgery
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    • v.40 no.8
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    • pp.558-563
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    • 2007
  • Background: Traumatic aortic rupture is a highly fatal condition in which a patient's outcome is strongly affected by other associated injuries. Selection of the appropriate surgical timing and the management plan is important. Material and Method: The medical records of the 15 traumatic descending thoracic aortic rupture patients who underwent the clamp & sew technique were retrospectively reviewed and checked for the presence of associated injuries and the postoperative course. Result: The hospital mortality was 6.07% (one patient). This patient died intra-operatively and the cause of the death was delayed hemoperitoneum. The mean operative time and aortic clamp time were $231{\pm}53.1$ and $13.1{\pm}5.3$ minutes, respectively. One patient complained the bowel obstructive symptoms at postoperative 10 days. We found the mechanical bowel obstruction on computed tomography of the abdomen, and segmental bowel resection was done. Conclusion: Although several surgical strategies may be appropriate for managing traumatic aortic rupture, the clamp & sew technique is a safe and effective method for the treatment of traumatic aortic injury.

Case Study on Fracture Type of Wooden Crib Wall (목재 Crib wall의 파괴유형에 대한 사례연구)

  • Shin, Changgun;Paik, Moonyeol;Hong, Cheolhwa;Bae, Wooseok
    • Journal of the Korean GEO-environmental Society
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    • v.14 no.7
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    • pp.39-50
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    • 2013
  • Crib wall is one of the segmental grid retaining walls using headers and stretchers to establish the framework of the wall. In this method, grids formed by the intersection of headers and stretchers are generally filled with the gravel to maintain the weight of the wall. Therefore, the construction can be carried out with higher speed and much economically when compared with the concrete retaining wall. Furthermore, it has high drain capacity, and environmentally friendly aspects also have been pointed out because the possibility of the planting at the front of the wall. However, in the wooden crib wall method, the relative movement between the individual headers and stretchers was generally recognized, and stress redistribution in the gravel filling was also observed when subjected to the external loading and self-weight of filling. In this study, it was analyzed fracture types and causes of wooden crib wall through detailed investigation and analysis of a large crib wall construction site. As a results, it occurred the damage in the members of 5.7% in a total of 2,315 locations and the damage of header occurred in the members of a header 80.2%. The 65.7% of the damaged header are concentrated in the lower part of crib wall. Therefore, it was analyzed the differences of fracture types and causes of wooden crib wall depending on the installation position and the kinds of members. It is considered basically the members of various forms of distortion and the grain affecting.

Standard Index Development for Comparing the Glomerular Number (사구체 수의 증감을 비교할 수 잇는 기준 개발)

  • Kim, Yong-Jin;Lee, Chi-Eun;Lee, Kook-Joo;Choi, Young-Ho;Hong, Jung-Suk
    • Journal of Yeungnam Medical Science
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    • v.18 no.1
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    • pp.85-93
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    • 2001
  • Background: The number of glomerulus has been considered one of the etiologic factors especially for focal segmental glomerulosclerosis. However, glomeruli are too many to calculate them correctly. Although the fractionator method has became convinced, in which they used selected sections, not whole kidney sections, with same intervals, it is also very hard to get good results. Because it is still very time-consuming and laborous work which leads to make big observers' biases. Methods and Materials: We designed the index for glomerular number to estimate the tendency of increase or decrease of the number of it in different kidneys and which was evaluated by other conventional methods including fractionator method. Index was based upon the theory by Nyengaard; "the number of glomerulus correlates with the weight of kidney, which is positively correlated with body weight". Calculating formula is the number of glomeruli/surface areas of cortices, which contain calculated glomeruli multiplies by kidney weight/body weight. Results: We applied this index to kidneys of FGS/Kist mouse and those of RFM/Nga mouse. The former is spontaneous glomerulosclerosis model with heavy protein uria and renal failure and the latter is the mother side of FGS/Kist mouse but has no glomerular disease or protein uria. The number of glomerulus of FGS/Kist mouse was decreased by 30% to those of RFM/Nga mouse. Conclusion: This index was useful and reliable for estimating the relative glomerular number between two groups.

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Finite Element Analysis of Ultra High Performance Fiber Reinforced Concrete 50M Composite Box Girder (초고강도 섬유보강 콘크리트 50M 합성 박스거더의 유한요소해석)

  • Makhbal, Tsas-Orgilmaa;Kim, Do-Hyun;Han, Sang-Mook
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.6 no.2
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    • pp.100-107
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    • 2018
  • The material and geometrical nonlinear finite elment analysis of UHPFRC 50M composite box girder was carried out. Constitute law in tension and compressive region of UHPFRC and HPC were modeled based on specimen test. The accuracy of nonlinear FEM analysis was verified by the experimental result of UHPFRC 50M composite girder. The UHPFRC 50M segmental composite box girder which has 1.5% steel fiber of volume fraction, 135MPa compressive strength and 18MPa tensile strength was tested. The post-tensioned UHPFRC composite girder consisted of three segment UHPFRC U-girder and High Strength Concrete reinforced slab. The parts of UHPFRC girder were modeled by 8nodes hexahedron elements and reinforcement bars and tendons were built by 2nodes linear elements by Midas FEA software. The constitutive laws of concrete materials were selected Multi-linear model both of tension and compression function under total strain crack model, which was included in classifying of smeared crack model. The nonlinearity of reinforcement elements and tendon was simulated by Von Mises criteria. The nonlinear static analysis was applied by incremental-iteration method with convergence criteria of Newton-Raphson. The validation of numerical analysis was verified by comparison with experimental result and numerical analysis result of load-deflection response, neutral axis coordinate change, and cracking pattern of girder. The load-deflection response was fitted very well with comparison to the experimental result. The finite element analysis is seen to satisfactorily predict flexural behavioral responses of post-tensioned, reinforced UHPFRC composite box girder.

Knee Joint Sparing Tumor Resection in 4years-Old Patient with Osteosarcoma - A Case Report - (4세 소아 대퇴골 골육종의 슬관절 보존형 절제 및 재건술 - 증례 보고 -)

  • Cho, Wan-Hyung;Cho, Sang-Hyun;Won, Ho-Hyun;Jeon, Dae-Geun
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.157-162
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    • 2008
  • Nowadays, most of the malignant bone tumor patient underwent limb salvage operation, however, reconstructive options for skeletally immature group are still controversial. There are three necessary conditions of most ideal reconstructive method in treating the skeletally immature children. As the epiphyseal plate sacrification is usually inevitable in malignant bone tumor around knee joint, ideal reconstructive technique would be as follows; 1)minimal or no damage to theadjacent epiphyseal plate, 2) maintaining mobile joint, 3) index procedure does not disturb subsequent operation such as lengthening. Segmental resection and reconstruction using autogenous pasteurized graft was done for 4 years old meta-diaphyseal osteosarcoma of femur. At 6 months from index operation, plain radiograph showed pasteurized bone resorption and loosening of fixation devise. To overcome the complication, we used allograft reconstruction by impacting the proximal host bone to the fluted portion of allobone. Three months later, proximal bone union was observed and patient showed good functional outcome.

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