• 한국자기공명학회논문지
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• 제18권1호
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• pp.36-40
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• 2014

Predicting secondary structure of protein through assigned backbone chemical shifts has been used widely because of its convenience and flexibility. In spite of its usefulness, chemical shift based analysis has some defects including isotopic shifts and solvent interaction. Here, it is shown that corrected chemical shift analysis for secondary structure of protein. It is included chemical shift correction through consideration of deuterium isotopic effect and calculate chemical shift index using probability-based methods. Enhanced method was applied successfully to one of the proteins from Mycobacterium tuberculosis. It is suggested that correction of chemical shift analysis could increase accuracy of secondary structure prediction of protein and small molecule in solution.

• 한국자기공명학회논문지
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• 제8권2호
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• pp.115-126
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• 2004

Four secondary metabolites from an unidentified tunicate were isolated by treatment with trichloroethyl chloroformate(TECF) or acetic anhydride in pyridine. Their structures were determined by an extensive NMR analysis and the configuration of diacetyl derivatives(3a, 4a) was assigned by comparing with NMR data of a similar compound. Three new naturally occurring compounds (1, 3, 4) showed potent brine shrimp lethality and antifungal effect against Candia albicans.

• International Journal of Naval Architecture and Ocean Engineering
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• 제5권2호
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• pp.313-323
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• 2013

Offshore floating structures have so-called moonpool in the centre area for the purpose of drilling, installation of subsea structures, recovery of Remotely-Operated Vehicle (ROV) and divers. However, this vertical opening has an effect on the operating performance of floating offshore structure in the vicinity of moonpool resonance frequency; piston mode and sloshing mode. Experimental study based on model test was carried out. Moonpool resonance of floating offshore structure on fixed condition and motion free condition were investigated. And, the effect of cofferdam which is representative inner structure inside moonpool was examined. Model test results showed that Molin's theoretical formula can predict moonpool resonance on fixed condition quite accurately. However, motion free condition has higher resonance frequency when it is compared with that of motion fixed. The installation of cofferdam moves resonance frequency to higher region and also generates secondary resonance at lower frequency. Furthermore, it was found that cofferdam was the cause of generating waves in the longitudinal direction when the vessel was in beam sea.

• Structural Engineering and Mechanics
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• 제42권5호
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• pp.677-699
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• 2012

This article studies the secondary resonances of a clamped-clamped microresonator under combined electrostatic and piezoelectric actuations. The electrostatic actuation is induced by applying the AC-DC voltage between the microbeam and the electrode plate that lies at the opposite side of the microbeam. The piezoelectric actuation is induced by applying the DC voltage between upper and lower sides of piezoelectric layer. It is assumed that the neutral axis of bending is stretched when the microbeam is deflected. The drift effect of piezoelectric layer (the phenomenon where there is a slow increase of the free strain after the application of a DC field) is neglected. The equations of motion are solved by using the multiple scale perturbation method. The system possesses a subharmonic resonance of order one-half and a superharmonic resonance of order two. It is shown that using the DC piezoelectric actuation, the sensitivity of AC-DC electrostatically actuated microresonator under subharmonic and superharmonic resonances may be tuned. In addition, it is shown that the tuning domain of the microbeam under combined electrostatic and piezoelectric actuations at subharmonic and superharmonic conditions is larger than the tuning domain of microbeam under only the electrostatic actuation.

• Structural Engineering and Mechanics
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• 제61권4호
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• pp.497-510
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• 2017

A framed structure may be composed of two sub-structures, which are linked by a hinged joint. One sub-structure is the primary system and the other is the secondary system. The primary system, which is subjected to the periodic external load, can give rise to an auto-parametric resonance of the second system. Considering the geometric-stiffness effect produced by the axially internal force, the element equation of motion is derived by the extended Hamilton's principle. The element equations are then assembled into the global non-homogeneous Mathieu-Hill equations. The Newmark's method is introduced to solve the time-history responses of the non-homogeneous Mathieu-Hill equations. The energy-growth exponent/coefficient (EGE/EGC) and a finite-time Lyapunov exponent (FLE) are proposed for determining the auto-parametric instability boundaries of the structural system. The auto-parametric instabilities are numerically analyzed for the two frames. The influence of relative stiffness between the primary and secondary systems on the auto-parametric instability boundaries is investigated. A phenomenon of the "auto-parametric internal resonance" (the auto-parametric resonance of the second system induced by a normal resonance of the primary system) is predicted through the two numerical examples. The risk of auto-parametric internal resonance is emphasized. An auto-parametric resonance experiment of a ${\Gamma}$-shaped frame is conducted for verifying the theoretical predictions and present calculation method.

• 한국자기공명학회논문지
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• 제10권1호
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• pp.96-104
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• 2006

The gene coding for APG8a (At4g21980), a protein from Arabidopsis thaliana, is involved in the autophagy process. The protein is an interesting candidate for structure determination by NMR spectroscopy. Toward this end, APG8a has been produced recombinantly in Escherichia coli and typical NMR experiments such as $^{15}N-HSQC$, HNCA, HN(CO)CA, CBCA(CO)NH, HCCH-TOCSY, HNCO were performed. The backbone resonances, HN, N, CA, CB, and C' were sequence-specifically assigned, and the secondary structures including 3 $\alpha$ helices and $4\beta$ strands were deduced based on the assignments. Due to the intrinsic flexibility or the effect of the denaturant, the backbone resonances were not fully observed. Since the structure calculation by NMR data was not possible, the 3-dimensional model was built based on the sequence homology, and compared with the NMR results. The overall structure of the model could explain and complement the NMR derived secondary structures.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 A
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• pp.266-267
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• 2006

A coupling capacitor voltage transformer (CCVT) is used in extra high voltage and ultra high voltage transmission systems to obtain the standard low voltage signal for protection and measurement. To obtain the high accuracy at the power system frequency, a tuning reactor is connected between a capacitor and a voltage transformer (VT). Thus, no distortion of the secondary voltage is generated when no fault occurs. However, when a fault occurs, the secondary voltage of the CCVT has some errors due to the transient components resulting from the fault. This paper proposes an algorithm for compensating the secondary voltage of the CCVT in the time domain. With the values of the secondary voltage of the CCVT, the secondary and the primary currents are obtained; then the voltage across the capacitor and the tuning reactoris calculated and then added to the measured secondary voltage. The proposed algorithm includes the effect of the non-linear characteristic of the VT and the influence of the ferro-resonance suppression circuit. Test results indicate that the algorithm can successfully compensate the distorted secondary voltage of the CCVT irrespective of the fault distance, the fault inception angle and the fault impedance.

• 대한기계학회논문집B
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• 제37권5호
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• pp.489-494
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• 2013

본 연구는 주기적인 강제 진동이 가해지는 액적의 모드 특성을 실험적으로 이해하는 것을 목적으로 하고 있다. 액적의 공진 주파수 예측을 수행하여 이론 및 실험적 해석을 통해 두 접근방법의 타당성을 파악하였으며, 초고속카메라를 사용하여 액적의 다양한 변형 특성-모드 형상, 분리, 미소 액적의 발생, 그리고 비틀림의 특성을 관찰하였다. 이론 해석 및 실험결과와의 비교에 있어 공진 주파수 값의 차이가 약 15% 이하라는 것이 도출되었으며 이러한 차이의 발생 원인으로 접촉선 마찰, 비선형벽 고착, 실험의 불확실성 등에 큰 영향을 받는 것으로 판단된다. 접촉선이 고정되어있을 경우와 작은 진폭 조건 하에서 액적의 모양은 대칭형상을 가졌으며, 공진 주파수에서의 로브의 크기는 주변부 주파수에서의 로브 크기보다 더 크게 된다는 점을 확인하였다.

• Structural Engineering and Mechanics
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• 제35권4호
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• pp.387-407
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• 2010

In this paper, using perturbation and Galerkin method, the response of a resonant viscoelastic microbeam to an electric actuation is obtained. The microbeam is under axial load and electrical load. It is assumed that midplane is stretched, when the beam is deflected. The equation of motion is derived using the Newton's second law. The viscoelastic model is taken to be the Kelvin-Voigt model. In the first section, the static deflection is obtained using the Galerkin method. Exact linear symmetric mode shape of a straight beam and its deflection function under constant transverse load are used as admissible functions. So, an analytical expression that describes the static deflection at all points is obtained. Comparing the result with previous research show that using deflection function as admissible function decreases the computation errors and previous calculations volume. In the second section, the response of a microbeam resonator system under primary and secondary resonance excitation has been obtained by analytical multiple scale perturbation method combined with the Galerkin method. It is shown, that a small amount of viscoelastic damping has an important effect and causes to decrease the maximum amplitude of response, and to shift the resonance frequency. Also, it shown, that an increase of the DC voltage, ratio of the air gap to the microbeam thickness, tensile axial load, would increase the effect of viscoelastic damping, and an increase of the compressive axial load would decrease the effect of viscoelastic damping.

• 한국소음진동공학회논문집
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• 제21권9호
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• pp.813-819
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• 2011

This paper predicted nonlinear dynamic responses of a cantilevered carbon nanotube(CNT) resonator incorporating the electrostatic forces and van der Waals interactions between the CNT cantilever and ground plane. The structural model of CNT includes geometric and inertial nonlinearities to investigate various phenomena of nonlinear responses of the CNT due to the electrostatic excitation. In order to solve this problem, we used Galerkin's approximation and the numerical integration techniques. As a result, the CNT nano-resonator shows the softening effect through saddle-node bifurcation near primary resonance frequency with increasing the applied AC and DC voltages. Also we can predict nonlinear secondary resonances such as superharmonic and subharmonic resonances. The superharmonic resonance of the nano-resonator is influenced by applied AC voltage. The period-doubling bifurcation leads to the subharmonic resonance which occurs when the nano-resonator is actuated by electrostatic forces as parametric excitation.