• Natural Product Sciences
• /
• v.21 no.3
• /
• pp.162-169
• /
• 2015

Hamamelis japonica (Hamamelidaceae), widely known as Japanese witch hazel, is a deciduous flowering shrub that produces compact clumps of yellow or orange-red flowers with long and thin petals. As a part of our ongoing search for phenolic constituents from this plant, eleven phenolic constituents including six flavonol glycosides, a chalcone glycoside, two coumaroyl flavonol glycosides and two galloylated compounds were isolated from the flowers. Their structures were elucidated as methyl gallate (1), myricitrin (2), hyperoside (3), isoquercitrin (4), quercitrin (5), spiraeoside (6), kaempferol 4'-O-β-glucopyranoside (7), chalcononaringenin 2'-O-β-glucopyranoside (8), trans-tiliroside (9), cis-tiliroside (10), and pentagalloyl-O-β-D-glucose (11), respectively. These structures of the compounds were identified on the basis of spectroscopic studies including the on-line LCNMR-MS and conventional NMR techniques. Particularly, directly coupled LC-NMR-MS afforded sufficient structural information rapidly to identify three flavonol glycosides (2 - 4) with the same molecular weight in an extract of Hamamelis japonica flowers without laborious fractionation and purification step. Cytotoxic effects of all the isolated phenolic compounds were evaluated on HCT116 human colon cancer cells, and pentagalloyl-O-β-D-glucose (11) was found to be significantly potent in inhibiting cancer cell growth.

• Korean Journal of Pharmacognosy
• /
• v.47 no.1
• /
• pp.49-54
• /
• 2016

In our search for natural products affecting blood circulation, the n-butanol fraction from whole plant of Glehnia littoralis Fr. Schm. (GLB) improved blood lipid parameters, and ameliorated obesity in high-fat-diet (HFD)-fed C57BL/6 mouse model. Hyperlipidemia was induced by high-fat-diet for 4 weeks, and then GLB was orally administrated with 400 mg/kg/day for 4 weeks. GLB-treated group showed that the gain in body weight was significantly attenuated, the levels of total cholesterol and triglyceride significantly lowered on blood chemical analysis, and significantly prolonged the mice bleeding time when compared with those of HFD control group. Concomitantly, phytochemical composition of GLB was investigated by HPLC-hyphenated spectroscopy, and two major phenolic compounds, rutin and chlorogenic acid were identified in the GLB. Taken together, these results indicate that GLB has cardiovascular protective effects and could be a natural medicine candidate for the prevention of cardiovascular disease.

• Journal of Korean society of Dental Hygiene
• /
• v.10 no.6
• /
• pp.1095-1105
• /
• 2010

Objectives : This paper is designed to help the public prevent their future dental caries, based on the studies of xylitol about it's efficacy and effectiveness, and its appropriate usage. Methods : This study of xylitol on the basis of existing research papers and literature is not only to learn about the mechanism of what xylitol acts, but also to search the effectiveness of incompleteness of xylitol-containing foods, bacterial infection between xylitol and mother-baby, and the side-effects of xylitol. Results : 1. Xylitol's continuous intake of teeth effects the decrease of calculus amount, cleanness of teeth, as well as the remineralization process. The xylitol effect varies depending on the weight of xylitol, which has no effect on root caries. 2. Mouth gargle solution is higher resistant against acids; recalcification is significantly reduced; and remineralization effect represents. 3. It is reported that regular consumption of xylitol by mothers just during two years after birth has significantly decreased the spread possibility of mutans streptococcei. 4. The reduction of dental caries by xylitol is happened by its restraining the growth of bacteria resource caries, with their presence in amount of uncontrolled growth. 5. When a small amount of eating xylitol is absorbed slowly into gastrointestinal tract, being followed by glucose metabolism in the liver, while its excessive amount of eating can cause gastrointestinal problems. Conclusion : Dental hygienists should be required to provide dental information to the public on the basis of academic knowledge. In situation that one is not yet sure of xylitol on solid and multifaceted researches, there must be needed more accurate and detailed reviews on the side-effects of xylitol and the overall impact on the oral environments.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.13 no.1
• /
• pp.141-146
• /
• 2018

The authors' author keywords are the most important elements that characterize the contents of the paper, By analyzing this in real time and providing it to users, It is possible to grasp research trends. Unstructured data of a journal created in a paper is constructed as a database, make use of this to make index data structure that can search in real time. In the index data structure, a thesis containing a specific keyword is searched, By extracting and clustering the author keywords, By presenting to the user a word cloud that can be displayed by size according to the weight, designed a method to visualize research trends. We also present the results of the research trend analysis of the keywords "virus" and "iris recognition" in the implemented system.

• Corrosion Science and Technology
• /
• v.9 no.5
• /
• pp.196-200
• /
• 2010

Recently porous metal has been used as supporting metal in planar type SOFC. In order to search optimum alloys for porous metal support and estimate the stability of metal-supported SOFC at high temperature, it is necessary to investigate the oxidation behaviors of porous material for metal support in comparison with dense material. Oxidation tests of porous and dense stainless steels were conducted at $600^{\circ}C$ and $800^{\circ}C$. Since the specific surface area of porous material is much larger than that of dense material, surface area should be considered in order to compare the oxidation rate of porous stainless steel with that of dense stainless steel. The specific surface area of porous body was measured using image analyzer. The weight gain of porous stainless steel was much greater than those of dense stainless steels due to its larger specific surface area. considering the specific surface area, the oxidation rate of porous stainless steel is likely to be the same as that of dense stainless steel with the same surface area. The change in chromium content in stainless steel during oxidation was also investigated. The experimental result in chromium content in stainless steel during oxidation corresponded with the calculated value. While the change in chromium content in dense stainless steel during oxidation is negligible, chromium content in porous stainless steel rapidly decreases with oxidation time due to its large specific surface area. The significant decrease in chromium content in porous stainless steel during oxidation may affect the oxidation resistance of porous stainless steel support and long term stability of metal-supported SOFC.

• Korean Journal of Weed Science
• /
• v.17 no.4
• /
• pp.375-381
• /
• 1997

When the rice straw mulched, the inhibition of weed growth was observed in the paddy field. If we use these allelopathic effect of decreased weed establishment, we can save labor, and protect environment. Aqueous extract of rice straw were bioassayed using water foxtail seeds to investigate chair effects on the germination and the growth, and to identify allelopathic compounds. The major results obtained were summarized as follows : Aqueous extract was fractioned by solvent, among various fractions, II-3, II-4 fractions inhibited the coleoptile and the radical of water foxtail, by 100%, respectively. There were fumaric acid and 4 unknown organic acids. Seven organic acids including fumaric acid inhibited the growth and germination of water foxtail in $10^{-2}$M solution. One of the most effective allelopathic compounds in rice straw was identified the unknown organic acid, as molecular weight 253, by GC/MS.

• Magazine of the Korean Society of Agricultural Engineers
• /
• v.29 no.4
• /
• pp.73-92
• /
• 1987

Formulation of the geometric optimization for truss structures based on the elasticity theory turn out to be the nonlinear programming problem which has to deal with the cross-sectional area of the member and the coordinates of its nodes simultaneously. A few techniques have been proposed and adopted for the analysis of this nonlinear programming problem for the time being. These techniques, however, bear some limitations on truss shapes, loading conditions and design criteria for the practical application to real structures. A generalized algorithm for the geometric optimization of the truss structures, which can eliminate the above mentioned limitations, is developed in this study. The algorithm proposed utilizes the two-levels technique. In the first level which consists of two phases, the cross-sectional area of the truss member is optimized by transforming the nonlinear problem into SUMT, and solving SUMT utilizing the modified Newton Raphson method. In the second level, which also consists of two phases the geometric shape is optimized utillzing the unindirectional search technique of the Powell method which make it possible to minimize only the objective functlon. The algorithm proposed in this study is numerically tested for several truss structures with various shapes, loading conditions and design criteria, and compared with the results of the other algorithms to examine its applicability and stability. The numerical comparisons show that the two- levels algorithm proposed in this study is safely applicable to any design criteria, and the convergency rate is relatively fast and stable compared with other iteration methods for the geometric optimization of truss structures. It was found for the result of the shape optimization in this study to be decreased greatly in the weight of truss structures in comparison with the shape optimization of the truss utilizing the algorithm proposed with the other area optimum method.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.19 no.6
• /
• pp.828-833
• /
• 2009

WWW which is an applicable massive set of document on the Web is a thesaurus of various information for users. However, Search engines spend a lot of time to retrieve necessary information and to filter out unnecessary information for user. In this paper, we propose the EFAM(the Extended Fuzzy AHP Method) model to manage the Web resource efficiently, and to make a decision in the problem of specific domain definitely. The EFAM model is concerned with the emotion analysis based on the domain corpus information, and it composed with systematic common concept grids by the knowledge of multiple experts. Therefore, The proposed the EFAM model can extract the documents by considering on the emotion criteria in the semantic context that is extracted concept from the corpus of specific domain and confirms that our model provides more efficient decision-making through an experiment than the conventional methods such as AHP and Fuzzy AHP which describe as a hierarchical structure elements about decision-making based on the alternatives, evaluation criteria, subjective attribute weight and fuzzy relation between concept and object.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.14 no.4
• /
• pp.875-885
• /
• 2010

CBR (Case-Based Reasoning) is a technique to infer the relationships between existing data and case data, and the method to calculate similarity and Euclidean distance is mostly frequently being used. However, since those methods compare all the existing and case data, it also has a demerit that it takes much time for data search and filtering. Therefore, to solve this problem, various researches have been conducted. This paper suggests the method of SE(Speed Euclidean-distance) calculation that utilizes the patterns discovered in the existing process of computing similarity and Euclidean distance. Because SE calculation applies the patterns and weight found during inputting new cases and enables fast data extraction and short operation time, it can enhance computing speed for temporal or spatial restrictions and eliminate unnecessary computing operation. Through this experiment, it has been found that the proposed method improves performance in various computer environments or processing rate more efficiently than the existing method that extracts data using similarity or Euclidean method does.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.18 no.6
• /
• pp.1294-1301
• /
• 2014

In this paper, separate probabilistic distribution models for voiced and unvoiced speech are estimated and utilized to improve speaker recognition performance. Also, in addition to the conventional mel-frequency cepstral coefficient, skewness, kurtosis, and harmonic-to-noise ratio are extracted and used for voiced speech intervals. Two kinds of scores for voiced and unvoiced speech are linearly fused with the optimal weight found by exhaustive search. The performance of the proposed speaker recognizer is compared with that of the conventional recognizer which uses mel-frequency cepstral coefficient and a unified probabilistic distribution function based on the Gassian mixture model. Experimental results show that the lower the number of Gaussian mixture, the greater the performance improvement by the proposed algorithm.