• Journal of Chest Surgery
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• v.23 no.6
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• pp.1204-1212
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• 1990

Recent social and medical developments have significantly changed both the concept of death and the criteria for its pronouncement. Instead of considering. the heart as central to the determination for death, it is now prevalent to use death of the brain as adequate for death regardless of cardiac function in most western countries. But the brain death theory is not yet legally accepted despite growing public interest in our country due mainly to customary and moral reasons. Subsequently heart transplantation, which necessitates the concept of brain death, still remains a possible surgical entity in the future. As a part of endeavor the evaluate social atmosphere for the legal acceptance of the concept of brain death and the availability of potential heart donors, a four-page questionnaire on brain death and cardiac transplantation was given to the sophomore students of a medical college in Seoul[n=116, group I] and their family members[n=83, group II ]. The groups were chosen under the assumptions that they lacked sophisticated medical knowledge but had general medical interest so reliable data could be obtained. The majority of respondents in both group I and II thought that they knew the concept of brain death[group I 99.1%, group II 93.3%] and the definition of heart transplantation[group I 94%, group II 67.6%] at least to some extent, but only a small proportion of them was proven to have correct knowledge: brain death[74.4%, group II 39. 8%], heart transplantation[group I 31.9%, group II 30.1%]. Most respondents answered in the affirmative for the legal approval of brain death[group I 87.8%, group Il 97.9%]. The possibility of medical usage of brain dead organs was the biggest reason for brain death[group I 52.9%, group Il 47.9%]. Ninety-one percent of group I and 89.1 percent of group II responded that they were willing to give permission for donating the heart of brain-dead family members. Fifty-nine percent of group I and 51.9 percent of group II wanted their own heart donated. These results suggest, despite some inherent sampling limitations, that favorable responses to brain death and heart transplantation can be obtained among the general public if they are properly informed.

• Journal of the Korean Chemical Society
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• v.30 no.5
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• pp.483-487
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• 1986

The synthesis of $\beta-damascone$ (I), an odoriferous natural product, was investigated from 2,2,6-trimethylcyclohexanone (II); (II) was ethynylated by the action of monoacetylide anion prepared from acetylene and sec-butyllithium at -78${\circ}C$, to give an ethynylcarbinol(III), which was isomerized to an acetylcyclohexene(IV) by refluxing in aqueous oxalic or formic acid. (IV) was treated with sec-butyllithium, the enolate was reacted with freshly dried acetaldehyde, and the resultant $\beta-hydroxyketone$ (V) was dehydrated by TsOH to ${\beta}$-damascone, trans-2,6,6-trimethyl-1-crotonyl-1-cyclohexene(I).

• Journal of The Korean Astronomical Society
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• v.34 no.3
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• pp.167-179
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• 2001

A molecular line survey towards the UC H II region G34.3+0.15 from 155.3 to 165.3GHz has been conducted with the TRAO 14-m radio telescope. Combined with our previous observations from 84.7 to 115.6GHz and 123.5 to 155.3GHz (Paper I), the spectral coverage of this survey in G34.3+0.15 now runs from 85 to 165 GHz. From these latest observations, a total of 18 lines from 6 species were detected. These include four new lines corresponding to ${\Delta}$J = 0, ${\Delta}$K = 1 transitions of the $CH_3OH$ E-type species, and two new lines corresponding to transitions from $SO_2$ and $HC_3N$. These 6 new lines are $CH_3OH$[1(1) - 1(0)E], $CH_3OH$[2(1) - 2(0)E], $CH_3OH$[3(1) - 3(0)E], $CH_3OH$[4(1) - 4(0)E], $SO_2$[14(1, 13) -14(0, 14)] and $HC_3N$[18 -17]. We applied a rotation diagram analysis to derive rotation temperatures and column densities from the methanol transitions detected, and combined with NRAO 12-m data from Slysh et al. 1999. Applying a two-component fit, we find a cold component with temperature 13-16K and column density $3.3-3.4 {\times} 10^{14} cm^{-2}$, and a hot component with temperature 64 - 83K and column density $9.3{\times}10^{14} - 9.7 {\times} 10^{14} cm^{-2}$. On the other hand, applying just a one-component fit yields temperatures in the 47 -62 K range and column densities from $7.5-1.1 {\times} 10^{15} cm^{-2}$.

• Journal of Oral Medicine and Pain
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• v.13 no.1
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• pp.13-21
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• 1988

The author studied the vertical height of tooth crown and the amounts of alveolar bone resorption with age. All 84 subjects(44 male, 40female) who visited Dental hospital of Wonkwang University with no history of sever periodontal disease and no experience of periodontal surgery. 84 subject were divided into 3 groups by age, that is, group I(28-32yrs), group II(38-42yrs), and group III(48-52yrs). Informal radiogram with bite wing film(horizontal angulation : $0^{\circ}$, vertical angulation : $+5^{\circ}~+10^{\circ}$) were taken on premolar and molar area. The distances from cusp tip to cementoenamel junction (vertical height of tooth crown) and from cementoenamel junction alveolar crest(amount of alveolar bone resorption) were measured, and then recorded data from 946 teeth were statistically analysed. This study was undertaken to obtain the data for age estimation by the changes of tooth crown height and alveolar bone resorption in the point of forensic odontology. The obtained results were as follows : 1. The average crown height of mandibular right 1st. molar was 7.1mm in group I, 6.7mm in group II, and 6.6mm group III, and the average amount of alveolar bone resorption on mandibular right 1st. molar were 1.8mm in group I, 2.5mm in group II, and 3.0mm in group III. Ratio of tooth crown height to amount of alveolar bone resorption was 4.0:1 in groupI, 2.7:1 in group II, and 2.2:1 in group III, the ratio was decreased with age. 2. In comparison with upper teeth and lower teeth in ipsilateral side, the average value of tooth crown height and amount of alveolar bone resorption were slightly higher in upper arch than those in lower arch, but there was not a statistically significant difference. 3. The ratio of height of tooth crown to amount of alveolar bone resorption was decreased with age, and which depended mainly upon the change of amount of alveolar bone resorption rather than the change of tooth crown height.

• Journal of Oral Medicine and Pain
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• v.24 no.4
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• pp.467-477
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• 1999

Personality characteristics of orofacial pain patients was analyzed psychologically by means of the SCL-90-R. 36 TMD patients, 20 burning mouth syndrome(BMS) patients, 31 trigeminal neuralgia(TN) patients, 20 control I and 28 control II were subjected at Orofacial pain clinic, Department of Oral Medicine and Health Promotion Center, Pusan National University Hospital during the period from 1998 to 1999. The obtained results were as follows: 1. Mean values of T-scores on 9 basic scales in all the groups were within normal range. 2. The T-scores of SOM, O-C, ANX and HOS in TMD patient group were significantly higher than those in control I group, but there was no significant difference in all scales between TMD patient group and control II group. 3. The T-scores of SOM in BMS patient group was significantly higher than those in control I group, but there was no significant difference in all scales between BMS patient group and control II group. 4. The T-scores of SOM in TN patient group was significantly higher than those in control II group. 5. As compared with present and absent of the history of systemic diseases, there was no significant difference of the scales in TMD, BMS and TN patient groups but the T-scores of the patient groups with the history of systemic diseases tended to higher than those of the patient group without the history of systemic diseases. 6. As compared with acute and chronic groups, the T-scores of O-C, I-S, PAR, PSY in chronic BMS patient group were significantly higher than those in acute BMS patient.

• Journal of The Korean Society of Clinical Toxicology
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• v.1 no.1
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• pp.27-33
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• 2003

Purpose: According as the accessibility about drugs becomes various, the occurrence of drug intoxication is increasing. Since report that doxylamine causes rhabdomyolysis often, drug-induced rhabdomyolysis is one of the most important complications in patients with drug intoxication. Acute renal failure (ARF)'s availability is important to the management in rhabdomyolysis, but report about rhabdomyolysis or ARF occurrence for whole intoxicated drugs is lacking up to now. Methods: This research did to 61 patient who had rhabdomyolysis of drug intoxication. First, object patients were divided into two gruops: doxylamine-ingested (Group I) vs non-doxylamine ingested (Group II). And then we analyzed on the early patient's clinical events and laboratory data. We used ROC curve to recognize'the early clinical factors that could forecast ARF appearance among these patients in addition. Results: Almost rhabdomyolysis was happened by doxylamine in drug intoxication ($55.7\%$). However, as compared to group II, group I showed better clinical course, lesser ARF occurrence and hemodialysis requirement. In group II, time was longer in hospital reaching from intoxication, the ARF occurrence rate was higher ($52.6\%$). Analyzing the ROC curve to useful initial factors, they were creatinine, uric acid and interval time from ingestion to hospital. These cut-off values were 1.44 mg/dL, 6.8 mg/dL and 5 hrs. Sensitivity for ARF estimate was $100\%$, specificity $69-98\%$. Conclusion: Compared to group II, Doxylamine-ingested group showed good clinical course. Creatinine, uric acid, interval time from ingestion to hospital aided in ARF estimate in drug-induced rhabdomyolysis.

• The Journal of the Korean dental association
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• v.49 no.4
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• pp.219-226
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• 2011

Snoring and obstructive sleep apnea (OSA) are common sleep disordered breathing conditions. Habitual snoring is caused by a vibration of soft tissue of upper airway while breath in sleeping, and obstructive sleep apnea is caused by the repeated obstructions of airflow for a sleeping, specially airflow of pharynx. Researchers have shown that snoring is the most important symptom connected with the obstructive sleep apnea syndrome The treatment is directed toward improving the air flow by various surgical and nonsurgical methods. The current surgical procedures used are uvulopalatopharyngoplasty(UPPP), orthognathic surgery, nasal cavity surgery. Among the nonsurgical methods there are nasal continuous positive air pressure(CPAP), pharmacologic therapy. weight loss in obese patient, oral appliance(sleep splint). Sleep splint brings the mandible forward in order to increase upper airway volume and prevents total upper airway collapse during sleep. However, the precise mechanism of action is not yet completely understood, especially aerodynamic factor. The aim of this study evaluated the effect of conservative treatment of snoring and OSAS by sleep splint through measured aerodynamic change by an aerophone II. We measured a airflow, sound pressure level, duration, mean power from overall airflow by aerophone II mask. The results indicated that on a positive correlation between a decrease in maximum airflow rate and a decrease in maximum sound pressure level, on a negative correlation between a decrease in maximum airflow rate and a increase in duration.

• Asian Journal of Turfgrass Science
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• v.24 no.2
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• pp.117-124
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• 2010

Turfgrass survival and ocurrence of brown patch disease during summer season were investigated the forty six cultivars of cool season grasses in 6 species, popularly used in golf courses in Korea. Ocurrence of brown patch disease was evaluated two times in July. The percentage of turfgrass survival was investigated on Aug. 20 and on Sep. 20 in 2010. There were significant difference for the percentage of turfgrass survival and brown patch disease occurrence among cultivars. Brown patch disease caused by Rhizoctonia spp. and Pythium aphanidermatum with rDNA ITS were showed most susceptible in creeping bentgrass (Agrostis palustris Huds) cultivars and chewings fescue (Festuca rubra var. commutata Gaud) cultivars. The percentage of turfgrass survival during August to September was showed lower creeping bentgrass cultivars and chewings fescue cultivars than another cultivars. Among of 20 cultivars in Kentucky bluegrass (Poa pratensis L.) species were showed highest survival in cultivars of "Nuglade", "Cabernet", "Midnight II" and "Beyond". 6 cultivars of Tall fescue (Festuca arundinacea Schreb) were showed highest survival in cultivars of "Double sentry", "Inferno", and cultivars of "Accent II" in Perennial ryegrass (Lolium parenne L.) species.

• Archives of Reconstructive Microsurgery
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• v.15 no.1
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• pp.10-16
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• 2006

We retrospectively evaluated our results of replantations of distal digital amputations and analyzed the factors deterrent to the survival of replanted digits. From January 2004 to 2005 June, we performed 101 cases of replantations following complete amputations at or distal to interphalangeal joint level. The study included 98 patients with a mean age of 35.6 years (range 1 to 63 years). Amputation level correlated to zone I (distal to the lunula)in 47 cases and zone II (lunula to distal interphalangeal joint) in 54 cases according to Yamano's classification. According to the mechanism of amputation, 24 cases (22.9%) suffered from guillotine type injury, 27 cases (27.1 %) from avulsion type injury and 50 cases (50%) from crush type injury. In all cases, a single arterial anastomosis was performed. Venous anastomosis on either volar or dorsal side was performed in 12 cases of amputation in zone II. Salvage procedure for venous drainage was performed in 98 cases. The mean duration of salvage procedures was 5.9 days (ranging from 4 to 14 days). Successful replantation was achieved in 96 cases (95.1%), which included 93.7% cases in zone I amputations and 96.3% cases in zone II amputations. A single venous anastomosis was performed in 12 cases of amputation in zone II. All of them survived completely. Among the 5 cases that failed to survive, 3 cases were related with avulsion injury in zone I. Initial mechanism of injury determines the survival rate of amputated parts as it is directly related with the status of vessels and soft tissues. Meticulous precaution during the salvage procedure may affect the overall survival rate of distal digital replantations.

• Journal of Microbiology and Biotechnology
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• v.18 no.1
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• pp.95-103
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• 2008

Mushrooms are regarded as one of the well-known foods and biopharmaceutical materials with a great deal of interest. Polysaccharide ${\beta}$-glucan is the major component of mushrooms that displays various biological activities such as antidiabetic, anticancer, and antihyperlipidemic effects. In this study, we compared the immunostimulatory potency of polysaccharide fractions, prepared from liquid culture of pine-mushroom Tricholoma matsutake, with a potent immunogen lipopolysaccharide (LPS), and their molecular mechanisms on the functional activation of macrophages. We found that fraction II (TMF-II) was able to comparably upregulate or highly enhance the phenotypic functions of macrophages such NO production and cytokine (IL-$1{\beta}$, IL-6, IL-12, and TNF-${\alpha}$) expression, to LPS. TMF-II triggered the phosphorylation of $I{\kappa}B{\alpha}$, a critical step for NF-${\kappa}B$ activation and translocation. Of the upstream signaling enzymes tested, Src and Akt were thought to be the responsible upstream signaling components in induction of NO production, although TMF-II strongly upregulated the phosphorylation of all MAPK pathways. Therefore, our data suggest that T. matsutake-derived ${\beta}$-glucan may exert its immunostimulating activities with similar potency to LPS via activation of multiple signaling pathways linked to NF-${\kappa}B$ activation.