• Title/Summary/Keyword: Screening Hypothesis

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Review of Screening Procedure as Statistical Hypothesis Testing (통계적 가설검정으로서의 선별검사절차의 검토)

  • 권혁무;이민구;김상부;홍성훈
    • Journal of Korean Society for Quality Management
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    • v.26 no.2
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    • pp.39-50
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    • 1998
  • A screening procedure, where one or more correlated variables are used for screeing, is reviewed from the point of statistical hypothesis testing. Without assuming a specific probability model for the joint distribution of the performance and screening variables, some principles are provided to establish the best screeing region. A, pp.ication examples are provided for two cases; ⅰ) the case where the performance variable is dichotomous and ⅱ) the case where the performance variable is continuous. In case ⅰ), a normal model is assumed for the conditional distribution of the screening variable given the performance variable. In case ⅱ), the performance and screening variables are assumed to be jointly normally distributed.

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Effect of Nursing Intervention on the Knowledge, Health Beliefs, Self Efficacy and Rescreening Compliance of Cervical Cancer Screening Clients (검진유도 간호중재가 검진대상자의 자궁경부암 지식, 건강신념, 자기효능 및 재검진이행율에 미치는 효과)

  • Kim, Mi-Hyang;Choi, Soon-Hee
    • Women's Health Nursing
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    • v.13 no.3
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    • pp.157-164
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    • 2007
  • Purpose: This study was done to determine the effect of nursing interventions on the knowledge of cervical cancer, and health beliefs, self efficacy and rate of rescreening compliance. Method: This was a nonequivalent control group pretest-posttest design. The subjects were 93 women who had experienced cervical cancer screening in S city and were randomly assigned to the experimental or control group. Intervention tools were a screening record pocket book, phone-coach. and watching a video(17mins). The data was collected from April to December, 2003 and analyzed using an $X^2-test$. t-test and ANCOVA. Results: The 1st hypothesis, "The Posttest know ledge score of the experimental group will be significantly higher than that of the control group" was supported(F=11.16, p= .001). The 2nd hypothesis, "The Posttest health belief score of the experimental group will be significantly higher than that of the control group" was not supported(F=3.38, p= .069). The 3rd hypothesis, "The Posttest self efficacy score of the experimental group will be significantly higher than that of the control group" was supported(F=4.36, p= .040). The 4th hypothesis, "The Rescreening compliance rate of the experimental group after the nursing intervention will be significantly higher than that of the control group" was supported($X^2=3.45$, p= .050). Conclusion: This nursing intervention was effective in increasing the knowledge of cervical cancer, and self efficacy percentage of rescreening compliance. Therefore I think this intervention can be used for promoting the rescreening compliance of women.

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The Differentiating Effects of Job Seekers' Spec on Actual Employment: Focusing on Screening Hypothesis and Dual Labor Market Theory (구직자의 취업스펙이 실제취업에 미치는 영향에 대한 탐색적 연구: 선별이론 및 이중노동시장이론을 중심으로)

  • Jisung Park;Chiho Ok
    • Asia-Pacific Journal of Business
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    • v.13 no.4
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    • pp.11-24
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    • 2022
  • Purpose - The purpose of this study was to examine how job seekers' spec influence their actual employment especially focusing on the differentiating effects of applicants' specs depending on whether general or decent job employment. Design/methodology/approach - This study conducted analyses on 54,443 samples that incorporated data from the Graduates Occupational Mobility Survey for three years (2017-2019) collected by the Korea Employment Information Service. The linear probability model and logit model were used to examine the research questions. Findings - The results analyzed with the hierarchical regression model showed that most job seekers' specs were statistically significant in predicting employment status. Interestingly, there is a difference between the factors predicting employment for a general job and a decent job. This study suggests academic and practical implications for future research in the selection/ recruitment field by clarifying the critical factors to influence applicants' employment. Research implications or Originality The results of this study follow the screening hypothesis which explains that the applicants' specs have significant impacts on actual employment. Also, the dual labor market theory, which explains that applicants' specs differently affect actual employment between general and decent jobs, was reaffirmed.

Comparision of medical care utilization between newly detected hypertensive patients and known hypertensive patients (정기건강진단으로 밝혀진 고혈압환자의 의료이용에 관한 연구)

  • Cheon, Byung-Yool
    • Journal of Preventive Medicine and Public Health
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    • v.21 no.1 s.23
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    • pp.47-60
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    • 1988
  • The monthly ambulatory treatment days in newly detected hypertension group and known hypertension group were analyzed. The population was identified through the records of screening examination given by Korea Medical Insurance Corporation during the period from April to July, 1986. From the records of screening examination, 11,614 hypertensive patients were identified. By random sampling,959 patients were selected : among them, 544 fell under the category of known hypertension group and the other 415 fell under the newly detected hypertension group. The monthly ambulatory treatment days of these patients during the period from the April, 1985 to September, 1987 were analyzed in order to compare the exents of medical care utilization as well as to define and analyze the determinants responsible for the ambulatory treatment days between the two groups. The following results were obtained. 1) In the known hypertension group, no statistically significant changes in the ambulatory treatment days was observed after, in comparision to before, the screening examination. However, in the newly detected hypertension group the medical care utilization increased after the screening examination because of hypertension. 2) The ambulatory treatment days for hypertension of the known hypertension was statistically significant and higher than that of the newly detected hypertension group after screening examination. 3) There was no statistically significant change in the ambulatory treatment days in association with diseases other than hypertension in either group before and after the screening examination. 4) There was no statistically significant variable responsible for ambulatory treatment days in the known hypertension group. However, the income was a statistically significant variable in the newly detected hypertension group. 5) After the screening examination, the variables determining the ambulatory treatment days were the age of the patient and the diastolic blood pressure in the known hypertension group. These variables responsible for 2.02% of the total ambulatory treatment days. In the newly detected hypertension group, the income was a statistically significant variable which was responsible for 2.10% of total ambulatory treatment days. The above results satisfied the hypothesis that there would be no significant changes in the ambulatory treatment days before and after the screening examination in the known hypertension group. Also the hypothesis that there would be no significant change in the exents of medical care utilization for the diseases other than hypertension before and after the screening examination in either group was satisfied Also the medical care utilization was significantly higher in the known hypertension group than the newly detected hypertension group after the screening examination. This finding satisfied the hypothesis. This study was limited by the lack of considering fully the variables reponsible for the clinical symptoms of hypertension as well as for the individual characteristics. Thus, the result of this study are not fully adequate to define the determinants responsible for the exents of medical care utilization. In the future studies on medical rare utilization, additional variables should be considered.

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A Study on the Evaluation Methods of IRDS for Screening the Industrial Design Proposals (IRDS 시스템에 의한 디자인 컨셉트의 평가방법 연구)

  • 우흥룡
    • Archives of design research
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    • v.20
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    • pp.51-58
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    • 1997
  • This paper aims to aid a practical evaluation for screening out the design proposais under applying the IRDS system, which is developed a computer aided industrial design system as a computer application system. In this study, the author adopted 3 evaluation methods with criteria which have quantitative and qualitative attributes : the Intuitive Evaluation Methods(X), the Accumulative Evaluation Method(Y), the Benchmarking Evaluation Methods(Z). The results show that the 3 Methods have reciprocal relationships under reliability(r=0.0001). In analysis on the properties of the evaluation methods, the Evaluation Method (X) shows rapidity especially, the Evaluation Method (Y); relativity, the Evaluation Method(Z); importance respectively. The correlation analysis between the evaluation methods makes the null hypothesis denying, then we could adapt the research hypothesis. Therefore the correlation between them has positive relationship, and it shows thicker than the result of the 1st study.

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Interpretation of Quality Statistics Using Sampling Error (샘플링오차에 의한 품질통계 모형의 해석)

  • Choi, Sung-Woon
    • Journal of the Korea Safety Management & Science
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    • v.10 no.2
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    • pp.205-210
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    • 2008
  • The research interprets the principles of sampling error design for quality statistics models such as hypothesis test, interval estimation, control charts and acceptance sampling. Introducing the proper discussions of the design of significance level according to the use of hypothesis test, then it presents two methods to interpret significance by Neyman-Pearson and Fisher. Second point of the study proposes the design of confidence level for interval estimation by Bayesian confidence set, frequentist confidential set and fiducial interval. Third, the content also indicates the design of type I error and type II error considering both productivity and customer claim for control chart. Finally, the study reflects the design of producer's risk with operating charistictics curve, screening and switch rules for the purpose of purchasing and subcontraction.

가족배경이 자녀의 성격형성에 미치는 영향에 관한 연구 -자녀의 수 및 성 구성을 중심으로-

  • Choe, Jeong
    • Korea journal of population studies
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    • v.7 no.1
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    • pp.78-123
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    • 1984
  • This study is attempting to examine the possible determinants of the rise of the sex ratio at birth from 106 to 110 in past decade in Taiwan. The basic hypothesis for the sudden rise of the sex ratio at birth is due to a combination of prenatal sex determination and abortion. The reasoning for this hypothesis involves three types of considerations - motivation, norm, and access. The theory is evaluated by analyzing data from birth registration and a large and representative sampie of Taiwanese wives of childbearing age. The empirical data seem to support the theoretical preposition and the basic hypothesis that the rise of the sex ratio at birth in Taiwan is due to a combination of prenatal sex determination and abortion. There is striking evidence of son-preference in the rise of the sex ratio at birth in higher birth order. In 1990 the sex ratio was 119 for third births and 128 for fourth and fifth births compared to the expected 106. Also, the 1991 KAP data indicated that women who have only daughters but no any son are more likely to make prenatal sex screening and terminate their pregnancies in male live births at higher birth order. Obviously, genetic diagnosis through chorionic villus sampling which was available in recent years was misused for prenatal sex determination and sex selective abortion.

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Sex Preference and Sex Ratio at Birth: the Case of Taiwan (대만의 남아선호와 출생시 성비의 불균형)

  • Chang, Ming-cheng
    • Korea journal of population studies
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    • v.17 no.2
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    • pp.98-115
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    • 1994
  • This study is attempting to examine the possible determinants of the rise of the sex ratio at birth from 106 to 110 in past decade in Taiwan. The basic hypothesis for the sudden rise of the sex ratio at birth is due to a combination of prenatal sex determination and abortion. The reasoning for this hypothesis involves three types of considerations - motivation, norm, and access. The theory is evaluated by analyzing data from birth registration and a large and representative sampie of Taiwanese wives of childbearing age. The empirical data seem to support the theoretical preposition and the basic hypothesis that the rise of the sex ratio at birth in Taiwan is due to a combination of prenatal sex determination and abortion. There is striking evidence of son-preference in the rise of the sex ratio at birth in higher birth order. In 1990 the sex ratio was 119 for third births and 128 for fourth and fifth births compared to the expected 106. Also, the 1991 KAP data indicated that women who have only daughters but no any son are more likely to make prenatal sex screening and terminate their pregnancies in male live births at higher birth order. Obviously, genetic diagnosis through chorionic villus sampling which was available in recent years was misused for prenatal sex determination and sex selective abortion.

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Pharmacophore Modeling and Molecular Dynamics Simulation to Find the Potent Leads for Aurora Kinase B

  • Sakkiah, Sugunadevi;Thangapandian, Sundarapandian;Kim, Yong-Seong;Lee, Keun-Woo
    • Bulletin of the Korean Chemical Society
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    • v.33 no.3
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    • pp.869-880
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    • 2012
  • Identification of the selective chemical features for Aurora-B inhibitors gained much attraction in drug discovery for the treatment of cancer. Hence to identify the Aurora-B critical features various techniques were utilized such as pharmacophore generation, virtual screening, homology modeling, molecular dynamics, and docking. Top ten hypotheses were generated for Aurora-B and Aurora-A. Among ten hypotheses, HypoB1 and HypoA1 were selected as a best hypothesis for Aurora-B and Aurora-A based on cluster analysis and ranking score, respectively. Test set result revealed that ring aromatic (RA) group in HypoB1 plays an essential role in differentiates Aurora-B from Aurora-A inhibitors. Hence, HypoB1 used as 3D query in virtual screening of databases and the hits were sorted out by applying drug-like properties and molecular docking. The molecular docking result revealed that 15 hits have shown strong hydrogen bond interactions with Ala157, Glu155, and Lys106. Hence, we proposed that HypoB1 might be a reasonable hypothesis to retrieve the structurally diverse and selective leads from various databases to inhibit Aurora-B.

Future of Toxicology and Role of Asian Chemical Safety Network

  • Kaminuma, Tsuguchika
    • Toxicological Research
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    • v.17
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    • pp.241-249
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    • 2001
  • Toxicology is under challenge from several new trends in science and technology, namely computer, the Internet, genome projects, genomic technologies, and combinatorial chemistry. These new trends will drastically change research style of toxicology. In addition to conventional uni cellular tests and animal tests using rodents, computer simulation, DNA chips (microarrays), in vivo tests using simple model organisms such as nematodesor flies become important routine screening tests. How to arrange these tests in tiers will become a new problem. Endocrine disruptors hypothesis is a good example for this kind of futuristic approach. Computer, particularly the Internet, is also enabling toxicologists and regulatory experts to collaborate more closely. The IPCS (International Program for Chemical Safety) which is ajoint project of WHO, ILO and UNEP, is a well-known international collaborative research for chemical risk assessments. The GINC project of IPCS is an effort to utilize the Internet for such collaborations. Some efforts were also made to establish regional collaboration network in East Asia under this project.

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