• Journal of Ginseng Research
• /
• v.35 no.2
• /
• pp.149-154
• /
• 2011

In order to determine the efficacy of functional foods, objective measurement of the severity of atopic dermatitis (AD) after taking foods is important. The aim of this study was to conduct an objective evaluation of whether Korean red ginseng (KRG) might be helpful for improvement of skin condition and serum IgE in patients with AD. Thirty atopic patients (18 females and 12 males) participated in this study. Patients took KRG for 16 weeks. Bioengineering methods, including the corneometer and evaporimeter, were used at the start of the study and after 8 weeks and 16 weeks. In addition, we assessed serum IgE levels and the severity scoring of the atopic dermatitis (SCORAD) index. Transepidermal water loss and skin hydration showed significant improvement after 16 weeks. A significant decrease in the SCORAD index, as well as in serum IgE level, was observed after 16 weeks. Our results demonstrated that KRG may be helpful as a functional food for patients with AD.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.16 no.1
• /
• pp.179-190
• /
• 2003

Atopic dermatitis is a chronic, inflammatory skin disease characterized by intense pruritus and the course marked by exacerbation and remission. It has the characteristic symptoms of dry, itchy, scaly skin with cracks by typical distribution of lesions. Even though the etiology of atopic dermatitis is not fully understood, it is considered an allergic reaction whose onset is frequently and strongly associated with both hereditary and environmental factors. In the present clinical study, we studied the efficacy of internal herb-medicine, external herb medicine - ex. dermal oints, aqueous solutions, etc -, and steam therapy. The patient's SCORAD index was lowered 55.8 than before of which the SCORAD index was 74.8. On the basis of this study, it should be considered that the treatment of atopic dermatitis should be focused on the external therapy as steam therapy, dermal oint, a aqueous solution etc.

• The Journal of Pediatrics of Korean Medicine
• /
• v.23 no.3
• /
• pp.193-206
• /
• 2009

Objectives The purpose of this study is to evaluate the effects of Low Level Laser Therapy on Atopic dermatitis symptoms. Methods 19 patients (7 men, 12 women) were involved in this study. The intensity of SCORAD index (Erythema/darkening, Edema/papulation, Oozing/crust, Excoriation, Lichenification/prurigo, Dryness) and the symptom of SCORAD index (Pruritus) in two regions were measured. One region was treated by LLLT, the other region was not treated. Then a comparative study of index score of two regions was analyzed. Results After treatment, there were statistically significant differences in Edema/papulation, Excoriation (p<0.001), Oozing/crust (p<0.01), and Pruritus(p<0.05) index. Conclusions Based on the results, we concluded that LLLT is an effective in the treatment of atopic dermatitis. Also, further controlled studies with clinical cases of appropriate treatment time, wavelength, and intervals are needed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.27 no.3
• /
• pp.191-204
• /
• 2014

Objective : The purpose of this study is to investigate the effect of Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) for atopic dermatitis patients diagnosed as the febrile tendency. Method : This case study was done on 6 atopic patients with febrile tendency who have visited Korean Medicine Clinic from 2013.08.01. to 2014.04.30.. Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) was prescribed to all 6 patients and evaluated the symptom change through photographs and questionnaire. Objective SCORAD Index(OSI) was used to evaluate the objective symptom and VAS was used to evaluate the subjective change. Results & Conclusion : The Objective SCORAD index and VAS were decreased in all patients. The average OSI reduction score was 26.3. Most symptoms of 6 patients were improved. Gagamchengyoung-tang ($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) can be effective in patients who were diagnosed as febrile tendency.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.19 no.2
• /
• pp.223-232
• /
• 2006

Background : Many doctors are under a bias toward clinical severity in patients with atopic dermatitis. But the various studios show that atopic dermatitis may produce a range of impacts on the qualify of lift . Nevertheless there is much to be desired about the association between the quality of lift and atopic dermatitis in the department of Dermatology in Korean medicine. Objective : This study was conducted to investigate the impact of the atopic dermatitis on quality of life and explore prognostic factors that influence outcomes. Methods : 70 patients were recruited in this study rho write out more than 90% of Skindex-29 questionnaires. The function of total scores and three domain scores and SCORAD index was investigated and the correlation of each domain scores also . Result : The total scores, showed significant correlation with three domain scores in atopic dermatitis. The correlation of each three domain scores were significant. SCORAD index showed significant correlation with three domain scores and total scores. Conclusion : In this study atopic dermatitis efface of the quality of life in physical, social, and psychological factors. So we considered to the quality of life as well as clinical severity in patient with atopic dermatitis.

• The Journal of Pediatrics of Korean Medicine
• /
• v.21 no.3
• /
• pp.21-31
• /
• 2007

Objectives The purpose of this study is to investigate the clinical effect of Kami-chungsimyeunjatang on atopic dermatitis and to survey the general characteristics in children with atopic dermatitis. Methods 30 patients suffering from atopic dermatitis were treated with water extract of Kami-chungsimyeunjatang and the clinical evaluation were made by SCORAD index system before and after treatment. We also investigated some characteristics of improvements by using questionnaire. Results 1. Among 30 patients diagnosed as atopic dermatitis, 18 of the people were male(60%) and 12 of the people were female(40%). 2. Among 30 patients diagnosed as atopic dermatitis, 24 of them have family history of allergic disease(80%) and 18 of them have past history of allergic disease(60%). 3. The distribution of nursing method, 13 of them (44%) had powdered milk, 10(33%) of them had both breast milk and powdered milk, 7 of them (23%) had only breast milk. 4. 20 patients(67%) who have atopic dermatitis were less than 1 year old and 6 of them (20%) were between 1 or 2 years old. The initial lesion of 22(74%) of the patients were face and neck. 5. 9 patients(30%) of them answered that the symptoms are getting worse especially during the winter while 8 patients(25%)of them said summer. 6. The mean period of treatment value was $4.6{\pm}2.20$ months. 7. After treatment, there was statistically significant decrease(p<0.05) of extent, intensity, subjective symptoms and total SCORAD index score(p=0.001). 8. After treatment, 28(93%) of the patients were improved. Conclusions Considering the above results, we speculate that Kami-chungsimyeunjatang is effective in the treatment of atopic dermatitis, and further studies are needed with more clinical cases of hematological evaluation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.34 no.1
• /
• pp.66-88
• /
• 2021

Objectives : This study aims to report 3 cases of systemic atopic dermatitis improved by Korean medicine hospitalization care. Methods : Unlike outpatients, inpatients were supervised their lifestyle including dietary habits by physicians every morning and daily treated with acupuncture, herbal medicine including Bangpungtongseongsan-gagam, and Hwangryunhaedok-tang wet dressing therapy during all week. For dressing preparation, Hwangryunhaedok-tang was used to skin lesion except face. Mixed decoction of Lonicerae Flos and Forsythiae Fructus was used to facial lesion. Hwangryunhaedok-tang pharmacopuncture was injected to 2 patients. Western oral medicine and injection such as antihistamine or corticosteroids were prescribed by physician depending on each patient's condition. Symptoms were assessed with SCORAD index, IGA, and taking photos. Results : All patients showed the decrease in SCORAD index, IGA, skin lesion amelioration, and patient-subjective improvement. As time passes, dependence on western treatment also decreased and patients were able to endure pruritus without antihistamine injection during hospitalization. Conclusions : This study suggests that Korean medicine hospitalization care including acupuncture, herbal medicine, external therapy is effective for improving atopic dermatitis through decrease SCORAD index, IGA and ameliorating skin lesion.

• The Journal of Pediatrics of Korean Medicine
• /
• v.28 no.1
• /
• pp.1-6
• /
• 2014

Objectives This study aimed to evaluate the effects of atopic care program through observing atopic patients who have lived in atopic-free village located Geumsan of Chungnam province. Methods Seventeen children (boy 7, and girl 10) with atopic dermatitis had moved into atopic-free village of Geumsan, and they have been cared with atopic care program. Atopic dermatitis symptoms were measured every month using SCORAD (Scoring of Atopic Dermatitis) and EASI (Eczema Area and Severity Index) from March, 2012 to September, 2013. The changes of scores were analyzed using paired t-test. Results The median month of residence period was 19.9 months (range from 6 to 42 months). The atopic symptoms were significantly improved on SCORAD (p<0.01) and EASI (p<0.1) respectively. Conclusion Despite the limitation of the small number of study subjects, this study may provide the possibility of natural environment-based therapy for children with atopic dermatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.22 no.1
• /
• pp.219-236
• /
• 2009

Background : Recently the number of atopic dermatitis patients has increased, but the treatment of atopic dermatitis is not effective, and the recurrence rate of atopic dermatitis is high. Many patients are suffering from pruritus. A new standard treatment system is needed. Objective : This study investigated the effect of Oriental medicine program for atopic dermatitis patients during short term hospitalization. Method : 6 patients were admitted for short term hospitalization program. The program includes Acupuncture, herbal medicine, examination, education, cupping therapy, herbal dressing, exercise and etc. Everyday we evaluated the patients by Severity Scoring Atopic Dermatitis(SCORAD) index and took the photos of lesions, and the patients evaluated themselves by atopic dermatitis diary which consists of emotion, pruritus, sleep loss. Results : Admission duration was 7 to 14 days. The SCORAD scores of them were decreased. Most symptoms of 6 patients were improved. Especially herbal dressing was effective for severe oozing. Subjective scores of atopic dermatitis diary were reduced. Conclusion : We expect that the short term hospitalization program could be helpful for uncontrollable atopic dermatitis patients.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.24 no.1
• /
• pp.96-110
• /
• 2011

목적 : 본 임상시험을 통하여 혈열(血熱)형으로 변증된 아토피피부염의 한약 치료 후 임상 효능과 안전성을 관찰함으로써 아토피피부염에 대한 한약치료의 유용성을 평가하고자 한다. 방법 : 본 임상시험은 무작위배정, 이중맹검, 양성대조군, 평행 설계로 진행되었다. 자의에 의해 임상시험 동의서에 서명한 대상자 중 선정기준 및 제외기준에 부합된 36명의 대상자들에게 시험약과 양성대조약 과립제를 1일 3회(5.0g* 3회/ 1일) 4주간 복용하도록 하였다. 36명 중 31명의 환자가 4주간의 치료를 종료하였다(시호청간산 복용군: n = 16, 소풍산 복용군: n =15). 아토피피부염 증상을 평가하기 위해 Scoring atopic dermatitis (SCORAD) index와 Eczemaarea and severity index (EASI) 를 사용하여 시험 시작 전과 4주 후 시험 종료일에 환자들의 피부소견을 평가하였다. 아토피 피부염에 대한 한약치료의 안정성을 평가하기 위하여 치료 전후 혈중 AST, ALT, BUN, creatinine 변화를 검토하여 한약치료의 간/신독성 여부에 대해 조사하였다. 결과 및 결론: 두 군 모두에서 유의하게 SCORAD 점수와 EASI 점수가 감소하였으나 두 군 간의 차이는 유의하지 않았다. 부종/구진, 찰상 항목의 점수에는 두 군 간에 유의한 차이가 관찰되었다. 31명의 환자에게서 한약 치료 후 간장과 신장에 미치는 독성이 발견되지 않았으며 한약투여와 관련된 이상반응은 보고되지 않았다. 위의 결과로부터 시호청간산과 소풍산이 혈열형 아토피피부염에 대한 효과적이고 안전한 치료 방법이 될 수 있을 것으로 생각된다.